Initial assessment of immigrant patients in primary care
Aten Primaria. 2024 Feb 27;56(7):102896. doi: 10.1016/j.aprim.2024.102896. Online ahead of print.ABSTRACTThe clinical interview of immigrant patients requires cultural competence to ensure good understanding and correct communication, in addition to collecting specific information that differs from that of native patients, such as origin and migratory route or cultural identity. Screening for latent tuberculosis infection is recommended in certain cases and screening for other infections, both cosmopolitan with a higher prevalence in migrants (HIV, syphilis, hepatitis B and C) and imported (Chagas, intestinal parasites, st...
Source: Atencion Primaria - February 28, 2024 Category: Primary Care Authors: Mar ía Ángeles González Martínez Mar ía Jesús Castaño Suero Marta Guerrero Mu ñoz Agust ín Francisco Rossetti Ethel Sequeira Aymar Carme Roca Saumell Source Type: research

Initial assessment of immigrant patients in primary care
Aten Primaria. 2024 Feb 27;56(7):102896. doi: 10.1016/j.aprim.2024.102896. Online ahead of print.ABSTRACTThe clinical interview of immigrant patients requires cultural competence to ensure good understanding and correct communication, in addition to collecting specific information that differs from that of native patients, such as origin and migratory route or cultural identity. Screening for latent tuberculosis infection is recommended in certain cases and screening for other infections, both cosmopolitan with a higher prevalence in migrants (HIV, syphilis, hepatitis B and C) and imported (Chagas, intestinal parasites, st...
Source: Atencion Primaria - February 28, 2024 Category: Primary Care Authors: Mar ía Ángeles González Martínez Mar ía Jesús Castaño Suero Marta Guerrero Mu ñoz Agust ín Francisco Rossetti Ethel Sequeira Aymar Carme Roca Saumell Source Type: research

Validation of Candidate Host Cell Entry Factors for Bovine Herpes Virus Type-1 Based on a Genome-Wide CRISPR Knockout Screen
Viruses. 2024 Feb 15;16(2):297. doi: 10.3390/v16020297.ABSTRACTTo identify host factors that affect Bovine Herpes Virus Type 1 (BoHV-1) infection we previously applied a genome wide CRISPR knockout screen targeting all bovine protein coding genes. By doing so we compiled a list of both pro-viral and anti-viral proteins involved in BoHV-1 replication. Here we provide further analysis of those that are potentially involved in viral entry into the host cell. We first generated single cell knockout clones deficient in some of the candidate genes for validation. We provide evidence that Polio Virus Receptor-related protein (PVR...
Source: Herpes - February 24, 2024 Category: Infectious Diseases Authors: Wenfang Spring Tan Enguang Rong Inga Dry Simon Lillico Andy Law Paul Digard Bruce Whitelaw Robert G Dalziel Source Type: research

Things to Do in Sunny San Diego
The historic aircraft carrier, USS Midway Museum moored in Broadway Pier in San Diego. SHM Converge 2024 is just around the corner, taking place from April 12 to 15. While noting down the sessions you wish to attend and catching up with friends and colleagues (see our editorial board’s recommendations), remember to also enjoy the beautiful city of San Diego. San Diego is known as the birthplace of California, as it was the first location in the western U.S. where Europeans set foot, specifically Point Loma. It’s also the birthplace of the California burrito, which includes French fries and carne asada. The city is hom...
Source: The Hospitalist - February 23, 2024 Category: Hospital Management Authors: Lisa Casinger Tags: SHM Converge Source Type: research

Immunogenicity and lot-to-lot consistency of booster shot with Sabin inactivated poliomyelitis vaccine in Chinese children aged 18-24 Months: A phase Ⅳ clinical trial
In conclusion, as the anti-poliovirus antibodies gradually waned one year post sIPV primary vaccination, especially the type 2 antibody waned to a very low level, suggesting the importance of the booster immunization for children at the age of 18-24 months old. The booster shot can greatly enhance the antibody level and protect children from the potential risk of infection with WPV and VDPV by supplementing the anti-poliovirus type 2 immunity gap in the current real world. Clinic Trial Registration. NCT04224519.PMID:38388236 | DOI:10.1016/j.vaccine.2024.02.042 (Source: Vaccine)
Source: Vaccine - February 22, 2024 Category: Allergy & Immunology Authors: Qiongzhou Yin Yan Zheng Zhifang Ying Jingyu Li Ya Jiang Wenmei Bao Youjian Dou Yi Pu Jin Lei Haitao Yang Ruiju Jiang Yan Deng Zhimei Zhao Jing Pu Jing Yang Yadong Li Min Xu Wei Cai Yanchun Che Li Shi Source Type: research

Immunogenicity and lot-to-lot consistency of booster shot with Sabin inactivated poliomyelitis vaccine in Chinese children aged 18-24 Months: A phase Ⅳ clinical trial
In conclusion, as the anti-poliovirus antibodies gradually waned one year post sIPV primary vaccination, especially the type 2 antibody waned to a very low level, suggesting the importance of the booster immunization for children at the age of 18-24 months old. The booster shot can greatly enhance the antibody level and protect children from the potential risk of infection with WPV and VDPV by supplementing the anti-poliovirus type 2 immunity gap in the current real world. Clinic Trial Registration. NCT04224519.PMID:38388236 | DOI:10.1016/j.vaccine.2024.02.042 (Source: Vaccine)
Source: Vaccine - February 22, 2024 Category: Allergy & Immunology Authors: Qiongzhou Yin Yan Zheng Zhifang Ying Jingyu Li Ya Jiang Wenmei Bao Youjian Dou Yi Pu Jin Lei Haitao Yang Ruiju Jiang Yan Deng Zhimei Zhao Jing Pu Jing Yang Yadong Li Min Xu Wei Cai Yanchun Che Li Shi Source Type: research

Impact of war on terror on conspiracy theory beliefs: implications for polio vaccination in Pakistan
ConclusionPakistan authorities should develop comprehensive awareness-raising and educational campaigns to counter the impact of conspiracy theories, myths, and misconceptions regarding polio vaccination. (Source: Journal of Public Health)
Source: Journal of Public Health - February 20, 2024 Category: Health Management Source Type: research

Highlighting Heroes and Ignoring Villains: Visual Framing of Polio and Polio Vaccine in Newspapers
. (Source: Health Communication)
Source: Health Communication - February 19, 2024 Category: Health Management Authors: Muhammad IttefaqTaufiq AhmadShafiq Ahmad KambohSayyed Fawad Ali ShahHyunjin Seoa School of Communication Studies, James Madison Universityb Department of Communication, University of Marylandc School of Communication Studies, University of the Punjabd Sch Source Type: research

2022 Polio outbreak, Rockland County, NY: Cost evaluation of strategies to prevent future outbreaks of vaccine-preventable diseases
Vaccine. 2024 Feb 16:S0264-410X(24)00171-3. doi: 10.1016/j.vaccine.2024.02.025. Online ahead of print.ABSTRACTIn 1994, the World Health Organization Region of the Americas was declared polio-free. In July 2022, a confirmed case of paralytic polio in an unvaccinated adult resident of Rockland County, New York was reported by the New York State Department of Health (NYSDOH) and Rockland County Department of Health (RCDOH). While only one case was identified, a single case of paralytic polio represents a public health emergency in the United States. The patient's county of residence was identified to have low vaccination cove...
Source: Vaccine - February 17, 2024 Category: Allergy & Immunology Authors: Jamison Pike James Lueken Julie Zajac Ashley Tippins Shani Doss Adina De Coteau Chitra Punjabi Maria Souto Achal Bhatt Source Type: research

2022 Polio outbreak, Rockland County, NY: Cost evaluation of strategies to prevent future outbreaks of vaccine-preventable diseases
Vaccine. 2024 Feb 16:S0264-410X(24)00171-3. doi: 10.1016/j.vaccine.2024.02.025. Online ahead of print.ABSTRACTIn 1994, the World Health Organization Region of the Americas was declared polio-free. In July 2022, a confirmed case of paralytic polio in an unvaccinated adult resident of Rockland County, New York was reported by the New York State Department of Health (NYSDOH) and Rockland County Department of Health (RCDOH). While only one case was identified, a single case of paralytic polio represents a public health emergency in the United States. The patient's county of residence was identified to have low vaccination cove...
Source: Vaccine - February 17, 2024 Category: Allergy & Immunology Authors: Jamison Pike James Lueken Julie Zajac Ashley Tippins Shani Doss Adina De Coteau Chitra Punjabi Maria Souto Achal Bhatt Source Type: research

Viruses, Vol. 16, Pages 297: Validation of Candidate Host Cell Entry Factors for Bovine Herpes Virus Type-1 Based on a Genome-Wide CRISPR Knockout Screen
bert G. Dalziel To identify host factors that affect Bovine Herpes Virus Type 1 (BoHV-1) infection we previously applied a genome wide CRISPR knockout screen targeting all bovine protein coding genes. By doing so we compiled a list of both pro-viral and anti-viral proteins involved in BoHV-1 replication. Here we provide further analysis of those that are potentially involved in viral entry into the host cell. We first generated single cell knockout clones deficient in some of the candidate genes for validation. We provide evidence that Polio Virus Receptor-related protein (PVRL2) serves as a receptor for BoHV-1, mediat...
Source: Viruses - February 15, 2024 Category: Virology Authors: Wenfang Spring Tan Enguang Rong Inga Dry Simon Lillico Andy Law Paul Digard Bruce Whitelaw Robert G. Dalziel Tags: Article Source Type: research

Disaster after disaster: the outbreak of infectious diseases in Pakistan in the wake of 2022 floods
Ann Med Surg (Lond). 2023 Dec 8;86(2):891-898. doi: 10.1097/MS9.0000000000001597. eCollection 2024 Feb.ABSTRACTIn June 2022, Pakistan witnessed catastrophic floods, affecting millions of people. The ensuing epidemics of cholera, cryptosporidiosis, rotavirus infections, generalized diarrhoea, typhoid and paratyphoid fevers, as well as the frequency of vector-borne diseases including malaria and dengue fever, are studied in this investigation. It also explores the latest outbreak of poliomyelitis and the frequency of respiratory diseases such COVID-19, diphtheria, and tuberculosis, as well as how floods have contributed to s...
Source: Annals of Medicine - February 9, 2024 Category: Internal Medicine Authors: Marcel Alied Abdus Salam Sayed Mansoor Sediqi Patrick Amanning Kwaah Linh Tran Nguyen Tien Huy Source Type: research

Observational analysis of the immunogenicity and safety of various types of spinal muscular atrophy vaccines
ConclusionThese findings indicated that both the oral vaccine and inactivated vaccine had good safety and immunogenicity in infants aged  ≥ 2 months. The sIPV group generated higher levels of neutralizing antibodies in serum, particularly evident in the post-immunization GMT levels for types II and III. (Source: Inflammopharmacology)
Source: Inflammopharmacology - February 3, 2024 Category: Drugs & Pharmacology Source Type: research

Changes in self-perceived performance and satisfaction with performance of daily activities following interdisciplinary rehabilitation in people with late effects of polio
CONCLUSION: Interdisciplinary rehabilitation can enhance self-rated performance and satisfaction with performance of daily activities among people with LEoP. Future studies of rehabilitation for people with LEoP should use a prospective design and capture the participants' process of change related to their rehabilitation period.PMID:38306063 | DOI:10.3233/NRE-230219 (Source: NeuroRehabilitation)
Source: NeuroRehabilitation - February 2, 2024 Category: Rehabilitation Authors: Katja Appelin Lena-Karin Erlandsson Jan Lexell Eva M ånsson Lexell Source Type: research

GSE233949 G207 and PVSRIPO treatment of medulloblastoma and pediatric high grade glioma
Contributors : Eric M Thompson ; Gregory K Friedman ; Kevin StevensonSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensHSV G207 and polio:rhinovirus PVSRIPO are two different viral immunotherapies used to treat malignant brain tumors in children. While some patients experience durable survival with these viral immunotherapies, many children have no response. The purpose of this work is to explore these viral immunotherapies in pediatric high grade glioma (pHGG) and medulloblastoma in order to elucidate how tumor response to treatment and to identify putative biomarkers of response and ...
Source: GEO: Gene Expression Omnibus - January 31, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research