Adolescent Idiopathic Scoliosis Screening of Schoolgirls
In this study, consent forms were distributed to elementary schoolgirls between 11-13 years, at random, in the city of Riyadh. Out of 1,147 girls screened, 40 girls were positive on screening. In the clinic, nine girls were found to have no scoliosis, one had old poliomyelitis and one had lumbar lipoma. The remaining 29 girls had idiopathic scoliosis, giving a prevalence of 2.5%. However, the Cobb's angle was more than five degrees in nine girls only, reducing the prevalence of significant curves to 0.78%. The study was acceptable to all parties involved. We feel studies that address the issues of female screeners, transpo...
Source: Annals of Saudi Medicine - April 27, 2017 Category: Journals (General) Tags: ISSUE 6 Source Type: research

Written reminders increase vaccine coverage in Danish children - evaluation of a nationwide intervention using The Danish Vaccination Register, 2014 to 2015
This study indicates a marked effect of personalised written reminders, highest for the vaccines given later in the schedule in the older cohort. In addition, the reminders increased awareness about correct registration of vaccinations in DDV. (Source: Eurosurveillance)
Source: Eurosurveillance - April 27, 2017 Category: Infectious Diseases Source Type: research

Written reminders increase vaccine coverage in Danish children - evaluation of a nationwide intervention using The Danish Vaccination Register, 2014 to 2015.
This study indicates a marked effect of personalised written reminders, highest for the vaccines given later in the schedule in the older cohort. In addition, the reminders increased awareness about correct registration of vaccinations in DDV. PMID: 28488995 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 27, 2017 Category: Infectious Diseases Authors: Suppli CH, Rasmussen M, Valentiner-Branth P, Mølbak K, Krause TG Tags: Euro Surveill Source Type: research

IJERPH, Vol. 14, Pages 459: Immunization Strategies Targeting Newly Arrived Migrants in Non-EU Countries of the Mediterranean Basin and Black Sea
Conclusions: Although differing among countries, indications for immunizing migrants are in place in most of them. However, we cannot infer from our findings whether those strategies are currently functioning and whether barriers to their implementation are being faced. Further studies focusing on these aspects are needed to develop concrete and targeted recommendations for action. Since migrants are moving across countries, development of on-line registries and cooperation between countries could allow keeping track of administered vaccines in order to app ropriately plan immunization series and avoid unnecessary vaccinat...
Source: International Journal of Environmental Research and Public Health - April 25, 2017 Category: Environmental Health Authors: Cristina Giambi Martina Del Manso Maria Dente Christian Napoli Carmen Monta ño-Remacha Flavia Riccardo Silvia Declich Network for the control of cross-border health threats in the Mediterranean Basin and Black Sea for the ProVacMed project Tags: Article Source Type: research

Inactivated polio vaccines from three different manufacturers have equivalent safety and immunogenicity when given as 1 or 2 additional doses after bivalent OPV: Results from a randomized controlled trial in Latin America.
CONCLUSION: Current WHO prequalified IPV vaccines are safe and induce similar humoral and intestinal immunity after one or two doses. The parent study was registered with ClinicalTrials.gov, number NCT01831050. PMID: 28455172 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - April 25, 2017 Category: Allergy & Immunology Authors: Lopez-Medina E, Melgar M, Gaensbauer JT, Bandyopadhyay AS, Borate BR, Weldon WC, Rüttimann R, Ward J, Clemens R, Asturias EJ Tags: Vaccine Source Type: research

[Comment] Maximising the impact of inactivated polio vaccines
With the globally coordinated switch from the trivalent oral polio vaccine (OPV) to the bivalent OPV in April, 2016, the international public health community entered a new chapter in the endgame of polio. Although OPV has served as the cornerstone of polio eradication efforts over the past 30 years, trivalent inactivated polio vaccine (IPV) has re-ascended to prominence in the past year, now acting as the sole source of protective immunity against type 2 poliovirus in routine immunisation programmes. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - April 25, 2017 Category: Infectious Diseases Authors: Elizabeth B Brickley, Peter F Wright Tags: Comment Source Type: research

[Articles] Immunogenicity and safety of three aluminium hydroxide adjuvanted vaccines with reduced doses of inactivated polio vaccine (IPV-Al) compared with standard IPV in young infants in the Dominican Republic: a phase 2, non-inferiority, observer-blinded, randomised, and controlled dose investigation trial
The lowest dose (1/10 IPV-Al) of the vaccine performed well both after two and three doses. Based on these results, this new vaccine is under investigation in phase 3 trials. (Source: The Lancet Infectious Diseases)
Source: The Lancet Infectious Diseases - April 25, 2017 Category: Infectious Diseases Authors: Luis Rivera, Rasmus S Pedersen, Lourdes Pe ña, Klaus J Olsen, Lars V Andreasen, Ingrid Kromann, Pernille I Nielsen, Charlotte Sørensen, Jes Dietrich, Ananda S Bandyopadhyay, Birgit Thierry-Carstensen Tags: Articles Source Type: research

Polio and measles down the drain: Environmental Enterovirus Surveillance in the Netherlands, 2005-2015.
In conclusion, we detected PVs, Non-Polio EVs and measles virus in sewage and show that environmental surveillance is useful for poliovirus detection in the Netherlands where live Oral poliovirus Vaccine is not used and communities with lower vaccination coverage exist. EEVS led to the detection of EV types not seen in the CEVS showing that EEVS is complementary to CEVS.IMPORTANCE We show that environmental enterovirus surveillance complements clinical enterovirus surveillance for poliovirus detection, or exclusion, and for Non-Polio enterovirus surveillance.Even in the presence of adequate surveillance, only a very limite...
Source: Applied and Environmental Microbiology - April 21, 2017 Category: Microbiology Authors: Benschop KSM, van der Avoort HG, Jusic E, Vennema H, van Binnendijk R, Duizer E Tags: Appl Environ Microbiol Source Type: research

Dutch national immunization schedule: compliance and associated characteristics for the primary series
Conclusion: Delayed vaccination during the primary vaccination schedule occurs in one sixth of the Dutch children. Efforts to improve compliance should be focused in particular on preterm infants, infants with low birth weight and infants whose parents are not born in the Netherlands.What is Known:•A delayed start of vaccination leads to a longer period at risk for infectious diseases, e.g.pertussis•Delayed vaccination is associated with several factors including prematurity, low birth weight, family size, birth order, low socioeconomic status and health status of the childWhat is New:•Compliance with the re...
Source: European Journal of Pediatrics - April 20, 2017 Category: Pediatrics Source Type: research

Immunogenicity to poliovirus type 2 following two doses of fractional intradermal inactivated poliovirus vaccine: A novel dose sparing immunization schedule.
Abstract INTRODUCTION: The polio eradication endgame strategic plan calls for the sequential removal of Sabin poliovirus serotypes from the trivalent oral poliovirus vaccine (tOPV), starting with type 2, and the introduction of ≥1 dose of inactivated poliovirus vaccine (IPV), to maintain an immunity base against poliovirus type 2. The global removal of oral poliovirus type 2 was successfully implemented in May 2016. However, IPV supply constraints has prevented introduction in 21 countries and led to complete stock-out in>20 countries. METHODS: We conducted a literature review and contacted correspondin...
Source: Vaccine - April 20, 2017 Category: Allergy & Immunology Authors: Anand A, Molodecky NA, Pallansch MA, Sutter RW Tags: Vaccine Source Type: research

Editorial: A Terrible Time
This “Case Study” is very much different than the others included in this issue. Lyle Knutson was a college classmate of mine. At a recent class reunion Linda Knutson Strand, Lyle′s sister married to another classmate of mine told me about the episode of polio her brother endured and how it affecte d the entire family. I remember other children that I knew who also had polio and the polio epidemic of the early 50s was an event in this country worthy of being remembered. I think the piece also serves to remind us of how things were in rural Minnesota in the early 1950s. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - April 19, 2017 Category: Neurology Authors: John B. Bodensteiner Source Type: research

Childhood vaccinations and risk of acute lymphoblastic leukaemia in children
Conclusions: This nationwide cohort study provides no support of the proposed protective effect of childhood vaccination against childhood ALL. (Source: International Journal of Epidemiology)
Source: International Journal of Epidemiology - April 19, 2017 Category: Epidemiology Source Type: research

Editorial: A Terrible Time
This “Case Study” is very much different than the others included in this issue. Lyle Knutson was a college classmate of mine. At a recent class reunion Linda Knutson Strand, Lyle’s sister married to another classmate of mine told me about the episode of polio her brother endured and how it affecte d the entire family. I remember other children that I knew who also had polio and the polio epidemic of the early 1950s was an event in this country worthy of being remembered. I think the piece also serves to remind us of how things were in rural Minnesota in the early 1950s. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - April 19, 2017 Category: Neurology Authors: John B. Bodensteiner Source Type: research

Resurgence of Polio? Modern day Epidemic (P2.320)
Conclusions:Further studies and discussion are needed on this front, and the development of a vaccine is prudent before this becomes a pandemic as was Polio.Disclosure: Dr. Swamy has nothing to disclose. Dr. Morgan has nothing to disclose. (Source: Neurology)
Source: Neurology - April 17, 2017 Category: Neurology Authors: Swamy, N., Morgan, H. Tags: HIV, HTLV-I, PML, Other Viral Infections, and CJD Source Type: research

A Fatal Case of West Nile Virus Encephalitis Passively Transplanted to a post bone marrow transplant Pediatric Patient with AML (P3.304)
Objective:This case report focuses on neuroinvasive West Nile Virus (WNV) infection in an immunocompromised patient which was passively transplanted from a haploidentical related donor who was infected between screening and transplant.Background:West Nile virus (WNV) is a neurotrophic, mosquito-borne, single-stranded, flavivirus, that was first discovered in America in 1999. WNV can present with encephalitis, meningitis, or polio-like acute flaccid paralysis, which are rare in immunocompetent individuals (
Source: Neurology - April 17, 2017 Category: Neurology Authors: Breen, D., Risen, S., Lee, J. Tags: Zika, Chikungunya, West Nile Virus, and Other Viral Infections II Source Type: research

Accounting for polio survivors in the post-polio world
Publication date: 15–21 April 2017 Source:The Lancet, Volume 389, Issue 10078 Author(s): Sophie Cousins (Source: The Lancet)
Source: The Lancet - April 15, 2017 Category: Journals (General) Source Type: research

[World Report] Accounting for polio survivors in the post-polio world
International organisations promise that we can soon hope to live in a polio-free world, but for millions of polio survivors the struggle is not over. Sophie Cousins reports. (Source: LANCET)
Source: LANCET - April 14, 2017 Category: Journals (General) Authors: Sophie Cousins Tags: World Report Source Type: research

The Terrible Summer of ‘52…when Polio struck our family
Based on information gathered from the Knutson Siblings (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - April 14, 2017 Category: Neurology Authors: Linda Knutson Strand Tags: Case Studies issue Source Type: research

The Terrible Summer of 1952 … When Polio Struck Our Family
This is the story of my twin brother's struggle with polio. The story reflects the thoughts and feelings of Lyle and members of his family and describes how we all coped with the event. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - April 14, 2017 Category: Neurology Authors: Linda Knutson Strand Source Type: research

Comparison of clinical and laboratory characteristics during two major paediatric meningitis outbreaks of echovirus 30 and other non-polio enteroviruses in Germany in 2008 and 2013
In conclusion, E-30 meningitis in children shows a characteristic pattern of clinical features. To further characterise NPEV strains worldwide, continuous surveillance and typing of NPEV strains causing cent ral nervous system disease is warranted. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - April 13, 2017 Category: Microbiology Source Type: research

Cutaneous Cautery (Al-Kowie): A Study in a Pediatric Outpatient Clinic in Central Saudi Arabia
Cutaneous cautery is a traditional therapeutic technique practiced widely in Saudi Arabia. During an 11-month period, in a pediatric orthopedic clinic, 67 of 298 new patients (22%) were seen who had had cutaneous cautery. Their parents were interviewed by questionnaire. The largest proportion of cautery treatments had occurred in patients with polio. Though the group of patients with neurodevelopmental disorders outnumbered polio patients, less had had cautery. The parents' educational level did not seem to affect the decision to seek cautery treatment, and the patients' grandparents were often influential in the decision ...
Source: Annals of Saudi Medicine - April 12, 2017 Category: Journals (General) Tags: ISSUE 5 Source Type: research

The treatment of fatigue by non-invasive brain stimulation
Publication date: Available online 11 April 2017 Source:Neurophysiologie Clinique/Clinical Neurophysiology Author(s): Jean-Pascal Lefaucheur, Moussa A. Chalah, Alaa Mhalla, Ulrich Palm, Samar S. Ayache, Veit Mylius The use of non-invasive brain neurostimulation (NIBS) techniques to treat neurological or psychiatric diseases is currently under development. Fatigue is a commonly observed symptom in the field of potentially treatable pathologies by NIBS, yet very little data has been published regarding its treatment. We conducted a review of the literature until the end of February 2017 to analyze all the studies that ...
Source: Neurophysiologie Clinique - April 12, 2017 Category: Neuroscience Source Type: research

Acute Flaccid Paralysis surveillance in Bosnia and Herzegovina: recent isolation of two Sabin like type 2 poliovirus
This article is protected by copyright. All rights reserved (Source: Journal of Medical Virology)
Source: Journal of Medical Virology - April 11, 2017 Category: Virology Authors: Stefano Fontana, Gabriele Buttinelli, Stefano Fiore, Mirsada Mulaomerovic, Jela A ćimović, Concetta Amato, Roberto Delogu, Giovanni Rezza, Paola Stefanelli Tags: Short Communication Source Type: research

Relationship of depression and medications on incidence of falls among people with late effects of polio.
Abstract The purpose of this study was to determine if falls in polio survivors, with or without post-polio syndrome (PPS), are related to number of medications taken, use of anti-depressant or psychoactive medications, or self-report of depression. A survey was sent to 300 members of a regional polio support group, asking them to document their fall history, medications used, and the presence of depression. Depression was measured by self-report and with the Geriatric Depression Scale, short form (GDS-15). One hundred and seventy-two usable surveys were returned with 146 of those completing the medication list. S...
Source: Physiotherapy Theory and Practice - April 11, 2017 Category: Physiotherapy Authors: Da Silva CP, Zuckerman B, Olkin R Tags: Physiother Theory Pract Source Type: research

Solace in solidarity: Disability friendship networks buffer well-being.
Conclusions/Implications: Friends with disabilities can offer uniquely important informational and emotional support resources that buffer the impact of a functional impairment on well-being. Psychosocial interventions should help people with long-term disabilities build their peer support networks. (PsycINFO Database Record (c) 2017 APA, all rights reserved) (Source: Rehabilitation Psychology)
Source: Rehabilitation Psychology - April 10, 2017 Category: Rehabilitation Source Type: research

[Perspectives] Losing a patient
He made his way into my exam room supported by two metal crutches that braced at the elbow, lurching his withered legs forward, step by excruciating step. His spine was twisted and scoliotic, causing him to list precariously to the left. He was a wisp of a man, barely clocking in at 100 lb —wasted away, it looked like, from untreated polio and a lifetime of subsistence living. (Source: LANCET)
Source: LANCET - April 8, 2017 Category: Journals (General) Authors: Danielle Ofri Tags: Perspectives Source Type: research

Voluntarily Reported Immunization Registry Data: Reliability and Feasibility to Predict Immunization Rates, San Diego, California, 2013.
CONCLUSIONS: Consistency in factors predicting immunization coverage levels in a telephone survey and IIS data confirmed the feasibility of using voluntarily reported IIS data to assess immunization rates in children aged 19-35 months. PMID: 28379785 [PubMed - as supplied by publisher] (Source: Public Health Reports)
Source: Public Health Reports - April 7, 2017 Category: Global & Universal Tags: Public Health Rep Source Type: research

Surveillance Systems to Track Progress Toward Polio Eradication - Worldwide, 2015-2016.
Abstract Global measures to eradicate polio began in 1988; as of 2014, four of six World Health Organization (WHO) regions have been certified polio-free. Within the two endemic regions (African and Eastern Mediterranean), Nigeria, Afghanistan, and Pakistan have never interrupted transmission of wild poliovirus (WPV) (1). The primary means of detecting poliovirus transmission is surveillance for acute flaccid paralysis (AFP) among children aged
Source: MMWR Morb Mortal Wkl... - April 7, 2017 Category: Epidemiology Authors: Maes EF, Diop OM, Jorba J, Chavan S, Tangermann RH, Wassilak SG Tags: MMWR Morb Mortal Wkly Rep Source Type: research

Individualism and social solidarity in vaccination policy: some further considerations
AbstractThis commentary, in response to the paper by Boas et al [IJPHR December 2016], considers some of the wider ethical, cultural and practical factors that may influence the official response of a polio-free nation following the identification of introduced wild virus within its borders. It looks at factors influencing vaccine uptake internationally, using examples of nations striving to improve childhood vaccine uptake, the relevance of mandatory versus voluntary immunisation and the role of public education and misinformation. (Source: Israel Journal of Health Policy Research)
Source: Israel Journal of Health Policy Research - April 6, 2017 Category: Global & Universal Source Type: research

Long ‐Term Neuromuscular Outcomes of West Nile Virus Infection: A Clinical and Electromyograph Evaluation of Patients with a History of Infection
This article is protected by copyright. All rights reserved. (Source: Muscle and Nerve)
Source: Muscle and Nerve - April 5, 2017 Category: Internal Medicine Authors: Parveen Athar, Rodrigo Hasbun, Melissa N. Garcia, Lucrecia Salazar, Steven Woods, Kazim Sheikh, Kristy O. Murray Tags: Research Article Source Type: research

Basic Techniques for Lower Extremity Rehabilitation in Poliomyelitis Patients
Polio deformity is often the result of inappropriate preventive measures taken duringconvalescence. Most major deformities that cause significant disability can be prevented by splintage and physical therapy. If deformities of the hip, knee, and ankle are prevented duringthe late convalescent stage—three to six months—a patient with lower exremity weakness, whootherwise would not be able to walk, may become ambulatory with crutches and braces.Conservative and operative measures to correct established deformity are often necessary toconvert a non-ambulatory, house-bound patient to one who can re-enter daily soci...
Source: Annals of Saudi Medicine - April 3, 2017 Category: Journals (General) Tags: ISSUE 2 Source Type: research

Poliomyelitis
remains an important cause of morbidity among young people in many developing areas of the world. The extent of the disease is often underestimated (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - April 3, 2017 Category: Journals (General) Tags: ISSUE 2 Source Type: research

Stopping polio vaccines from evolving the ability to harm
Publication date: 1 April 2017 Source:New Scientist, Volume 234, Issue 3119 (Source: New Scientist)
Source: New Scientist - April 1, 2017 Category: Science Source Type: research

Increased immunization coverage addresses the equity gap in Nepal.
CONCLUSION: The improvement in immunization coverage between 2001 and 2014 in Nepal can mainly be attributed to the interventions targeting the disadvantaged populations. PMID: 28479621 [PubMed - in process] (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 1, 2017 Category: International Medicine & Public Health Authors: Kc A, Nelin V, Raaijmakers H, Kim HJ, Singh C, Målqvist M Tags: Bull World Health Organ Source Type: research

Vaccine hesitancy: parental, professional and public responsibility.
This article provides an analysis of vaccine hesitancy from an ethical perspective: parental, professional and public responsibilities are analysed and described according to the "responsibility of the fathers towards the children", as articulated by Hans Jonas in 1979. PMID: 28617263 [PubMed - in process] (Source: Ann Ist Super Sanita)
Source: Ann Ist Super Sanita - April 1, 2017 Category: Biomedical Science Authors: Di Pietro ML, Poscia A, Teleman AA, Maged D, Ricciardi W Tags: Ann Ist Super Sanita Source Type: research

[Reports] Estimation of polio infection prevalence from environmental surveillance data
A major obstacle to eradicating polio is that poliovirus from endemic countries can be reintroduced to polio-free countries. Environmental surveillance (ES) can detect poliovirus from sewage or wastewaters samples, even in the absence of patients with paralysis. ES is underused, in part because its sensitivity is unknown. We used two unique data sets collected during a natural experiment provided by the 2013 polio outbreak in Israel: ES data from different locations and records of supplemental immunization with the live vaccine. Data from the intersecting population between the two data sets (covering more than 63,000 peop...
Source: Science Translational Medicine - March 29, 2017 Category: Biomedical Science Authors: Berchenko, Y., Manor, Y., Freedman, L. S., Kaliner, E., Grotto, I., Mendelson, E., Huppert, A. Tags: Reports Source Type: research

Impact of maternal antibodies and infant gut microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants: protocol for a prospective cohort study
Introduction Gastroenteritis is the leading cause of morbidity and mortality among young children living in resource-poor settings, majority of which is attributed to rotavirus. Rotavirus vaccination can therefore have a significant impact on infant mortality. However, rotavirus vaccine efficacy in Sub-Saharan Africa and Southeast Asia is significantly lower than in high-income countries. Maternally derived antibodies, infant gut microbiota and concomitant oral polio vaccination have been proposed as potential reasons for poor vaccine performance in low-income settings. The overall aim of this study is to compare the role ...
Source: BMJ Open - March 29, 2017 Category: Journals (General) Authors: Sindhu, K. N. C., Cunliffe, N., Peak, M., Turner, M., Darby, A., Grassly, N., Gordon, M., Dube, Q., Babji, S., Praharaj, I., Verghese, V., Iturriza-Gomara, M., Kang, G. Tags: Open access, Infectious diseases, Paediatrics, Public health Protocol Source Type: research

Design, construction, and evaluation of "sensor lock": an electromechanical stance control knee joint.
CONCLUSIONS: The feasibility of this new knee joint with AB people was demonstrated. Implications for rehabilitation Stance control knee ankle foot orthoses (SCKAFOs) are designed to stop knee flexion in stance phase and provide free knee movement during swing phase of walking. Due to their high cost, size, excessive weight, and poor performance, few SCKAFO were optimal clinically and commercially. The feasibility of the new knee joint with able-bodied people and poliomyelitis subjects was demonstrated. PMID: 28350511 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation. Assistive Technology.)
Source: Disability and Rehabilitation. Assistive Technology. - March 28, 2017 Category: Rehabilitation Authors: Arazpour M, Ahmadi Bani M, Baniasad M, Samadian M, Golchin N Tags: Disabil Rehabil Assist Technol Source Type: research

Polio Eradication in Pakistan: Call for Alliance.
Authors: Mahmood SU, Ahmed SA, Shoaib M, Khan T, Majeed M PMID: 28331440 [PubMed - in process] (Source: Ochsner Journal)
Source: Ochsner Journal - March 25, 2017 Category: Journals (General) Tags: Ochsner J Source Type: research

The Evolutionary Pathway to Virulence of an RNA Virus
Publication date: 23 March 2017 Source:Cell, Volume 169, Issue 1 Author(s): Adi Stern, Ming Te Yeh, Tal Zinger, Matt Smith, Caroline Wright, Guy Ling, Rasmus Nielsen, Andrew Macadam, Raul Andino Paralytic polio once afflicted almost half a million children each year. The attenuated oral polio vaccine (OPV) has enabled world-wide vaccination efforts, which resulted in nearly complete control of the disease. However, poliovirus eradication is hampered globally by epidemics of vaccine-derived polio. Here, we describe a combined theoretical and experimental strategy that describes the molecular events leading from OPV to viru...
Source: Cell - March 25, 2017 Category: Cytology Source Type: research

62-Year-Old Man With Back Pain and Lower Extremity Weakness
A 62-year-old man presented to the emergency department with progressive lower back pain and bilateral lower extremity weakness and numbness. His medical history was notable for poliomyelitis characterized by residual weakness of the proximal right lower extremity and chronic back pain. He also had a history of multilevel compressive radiculopathy in the lumbar spine. His symptoms had begun 6 weeks previously with both weakness and numbness in the lower extremities, which progressed to difficulty ambulating. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - March 25, 2017 Category: Internal Medicine Authors: Micah D. Yost, Laura S. Greenlund Tags: Residents' Clinic Source Type: research

Assessment of energy expenditure in individuals with post-poliomyelitis syndrome
Conclusion Patients with PPS had a higher energy expenditure during life, especially in occupational physical activity at ages 21-30 years, suggesting this decade is critical for the development of PPS.RESUMO O objetivo deste estudo foi identificar o gasto energ ético, retrospectivamente, em indivíduos com síndrome pós-poliomielite (SPP) na população brasileira. Métodos Foi utilizado o questionário Baecke para avaliação da atividade física habitual (AFH) nos pacientes com SPP, sequela de poliomielite (SP) e grupo controle (GC). Participaram do est...
Source: Arquivos de Neuro-Psiquiatria - March 24, 2017 Category: Neurology Source Type: research

The polio endgame: rationale behind the change in immunisation
The decades long effort to eradicate polio is nearing the final stages and oral polio vaccine (OPV) is much to thank for this success. As cases of wild poliovirus continue to dwindle, cases of paralysis associated with OPV itself have become a concern. As type-2 poliovirus (one of three) has been certified eradicated and a large proportion of OPV-related paralysis is caused by the type-2 component of OPV, the World Health Assembly endorsed the phased withdrawal of OPV and the introduction of inactivated polio vaccine (IPV) into routine immunisation schedules as a crucial step in the polio endgame plan. The rapid pace of IP...
Source: Archives of Disease in Childhood - March 20, 2017 Category: Pediatrics Authors: Garon, J., Patel, M. Tags: ADC Global child health Source Type: research

Evaluation of different shape-memory staple configurations against crossed screws for first metatarsophalangeal joint arthrodesis: A biomechanical study
The first metatarsophalangeal joint (MTPJ) may be affected by deformity, osteoarthritis and instability associated with rheumatoid arthritis and neuromuscular conditions such as cerebral palsy and polio. A reliable and widely used procedure for the treatment of these conditions is arthrodesis of the first MTPJ. Stable fixation of the arthrodesis is imperative for fusion to occur. (Source: Foot and Ankle Surgery)
Source: Foot and Ankle Surgery - March 18, 2017 Category: Orthopaedics Authors: H. Willmott, Z. Al-Wattar, C. Halewood, M. Dunning, A. Amis Source Type: research

Vaccine Associated Paralytic Poliomyelitis Unmasking Common Variable Immunodeficiency.
Abstract BACKGROUND: Oral polio vaccine can rarely lead to Vaccine-associated paralytic poliomyelitis (VAPP). CASE CHARACTERISTICS: A 2-year-old child with asymmetric paralysis of lower limbs following first booster of oral polio vaccine; type 2 Vaccine-derived poliovirus (VDPV) isolated. Subsequently, the child was diagnosed to have common variable immunodeficiency. OUTCOME: Paralysis gradually improved on follow-up; monthly intravenous immunoglobulin therapy started for primary immunodeficiency. MESSAGE: We need to evaluate children with VAPP for underlying immunodeficiency. PMID: 28361789 [P...
Source: Indian Pediatrics - March 15, 2017 Category: Pediatrics Authors: Gomber S, Arora V, Dewan P Tags: Indian Pediatr Source Type: research

Mobile phone-delivered reminders and incentives to improve childhood immunisation coverage and timeliness in Kenya (M-SIMU): a cluster randomised controlled trial
Publication date: April 2017 Source:The Lancet Global Health, Volume 5, Issue 4 Author(s): Dustin G Gibson, Benard Ochieng, E Wangeci Kagucia, Joyce Were, Kyla Hayford, Lawrence H Moulton, Orin S Levine, Frank Odhiambo, Katherine L O'Brien, Daniel R Feikin Background As mobile phone access continues to expand globally, opportunities exist to leverage these technologies to support demand for immunisation services and improve vaccine coverage. We aimed to assess whether short message service (SMS) reminders and monetary incentives can improve immunisation uptake in Kenya. Methods In this cluster-randomised controlled trial,...
Source: The Lancet Global Health - March 12, 2017 Category: Global & Universal Source Type: research

Maternal education, empowerment, economic status and child polio vaccination uptake in Pakistan: a population based cross sectional study
Objectives To explore the association of maternal education and empowerment with childhood polio vaccination using nationally representative data of Pakistani mothers in a reproductive age group. Design Cross-sectional. Setting Secondary analysis of Pakistan Demographic and Health Survey (PDHS), 2012–2013 data was performed. Participants Of the 13 558 mothers included in the survey sample, 6982 mothers were able to provide information regarding polio vaccinations. Main outcome measures Polio vaccination coverage among children aged up to 5 years was categorised as complete vaccination (all four oral pol...
Source: BMJ Open - March 10, 2017 Category: Journals (General) Authors: Khan, M. T., Zaheer, S., Shafique, K. Tags: Open access, Epidemiology, Infectious diseases, Public health Research Source Type: research

Why have the majority of recent polio cases occurred in countries affected by Islamist militancy? A historical comparative analysis of the political determinants of polio in Nigeria, Somalia, Pakistan, Afghanistan and Syria.
This article aims to understand why the last few areas where polio remains are affected by armed conflicts involving militant organizations that use Islam to legitimize their activities. The first section critically analyses the argument that Muslims' animosity towards polio vaccination programmes is a consequence of their irrational, backward, anti-Western theology. This argument is depoliticizing, ahistorical and orientalist. Moreover, it does not explain why Islamist militant groups' attitudes to polio vaccination campaigns vary between countries. The second section analyses official documents, newspaper articles, inter...
Source: Medicine, Conflict and Survival - March 9, 2017 Category: Global & Universal Tags: Med Confl Surviv Source Type: research

Advances in Surgical Critical Care 2017: Growing Population and Personalized Protocols
Critical care is a young specialty, initiated in 1953 when poliomyelitis patients required invasive mechanical ventilation, and even earlier for surgical patients recovering from anesthesia or traumatic injuries.1,2 The burden of critical illness globally is high and has been increasing as our population ages.3 (Source: Critical Care Clinics)
Source: Critical Care Clinics - March 9, 2017 Category: Intensive Care Authors: Lena M. Napolitano Tags: Preface Source Type: research