GERI-BD: A Randomized Double-Blind Controlled Trial of Lithium and Divalproex in the Treatment of Mania in Older Patients With Bipolar Disorder.
CONCLUSIONS: Both lithium and divalproex were adequately tolerated and efficacious; lithium was associated with a greater reduction in mania scores over 9 weeks.
PMID: 29088928 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Young RC, Mulsant BH, Sajatovic M, Gildengers AG, Gyulai L, Al Jurdi RK, Beyer J, Evans J, Banerjee S, Greenberg R, Marino P, Kunik ME, Chen P, Barrett M, Schulberg HC, Bruce ML, Reynolds CF, Alexopoulos GS, GERI-BD Study Group Tags: Am J Psychiatry Source Type: research
Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials
Conclusions:
This study incorporated genetic data into past ALS trials to determine treatment effects in a genetic post hoc analysis. Our results suggest that we should reorient our strategies toward finding treatments for ALS, start focusing on genotype-targeted treatments, and standardize genotyping in order to optimize randomization and analysis for future clinical trials. (Source: Neurology)
Source: Neurology - October 30, 2017 Category: Neurology Authors: van Eijk, R. P. A., Jones, A. R., Sproviero, W., Shatunov, A., Shaw, P. J., Leigh, P. N., Young, C. A., Shaw, C. E., Mora, G., Mandrioli, J., Borghero, G., Volanti, P., Diekstra, F. P., van Rheenen, W., Verstraete, E., Eijkemans, M. J. C., Veldink, J. H., Tags: Amyotrophic lateral sclerosis, Clinical trials Systematic review/meta analysis, All Genetics ARTICLE Source Type: research
Glomerular filtration rate is associated with free triiodothyronine in euthyroid subjects: Comparison between various equations to estimate renal function and creatinine clearance.
CONCLUSIONS: In euthyroid subjects renal function is associated with thyroid function status, especially by serum FT3, irrespective of the eGFR equation applied. In the euthyroid state, cystatin C-based eGFR equations are appropriate to assess the relationship of renal function with variation in thyroid function status.
PMID: 29079274 [PubMed - as supplied by publisher] (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - October 24, 2017 Category: Internal Medicine Authors: Anderson JLC, Gruppen EG, van Tienhoven-Wind L, Eisenga MF, de Vries H, Gansevoort RT, Bakker SJL, Dullaart RPF Tags: Eur J Intern Med Source Type: research
Lithium Toxicity after Roux-en-Y Gastric Bypass is Not Just Limited to Perioperative Period
TO THE EDITOR: There have now been several case reports and a recent case series by Bingham et al.1 regarding lithium toxicity following Roux-en-Y gastric bypass surgery.2,3 These cases have routinely examined the relationship only in the perioperative period. It is important to note that in the discussions of these cases they make mention of an in vitro experiment that shows the dissolution of unaltered lithium carbonate capsules to be about double in the postgastric bypass environment as compared to pregastric bypass environment. (Source: Psychosomatics)
Source: Psychosomatics - October 13, 2017 Category: Psychiatry & Psychology Authors: Brian Wasserman, Wei Jiang Tags: Letter to the editor Source Type: research
Lithium Treatment Aggregates the Adverse Effects on Erythrocytes Subjected to Arsenic Exposure.
Abstract
The present study was designed to investigate the effects of lithium treatment on red blood cells which were given arsenic exposure. Long-term lithium therapy is being extensively used for the treatment of bipolar disorders. Arsenic is a group I carcinogen and a major toxic pollutant in drinking water that affects millions of people worldwide. Male SD rats were segregated into four groups, viz. normal control, lithium treated, arsenic treated, and lithium + arsenic treated. Lithium was supplemented as lithium carbonate at a dose level of 1.1 g/kg diet for a period of 8 weeks. Arsenic was given i...
Source: Biological Trace Element Research - October 7, 2017 Category: Biology Authors: Bhardwaj P, Jain K, Dhawan DK Tags: Biol Trace Elem Res Source Type: research
C(sp(3))-H amination of 8-methylquinolines with azodicarboxylates under Rh(iii) catalysis: cytotoxic evaluation of quinolin-8-ylmethanamines.
Abstract
The rhodium(iii)-catalyzed C(sp(3))-H amination reaction of 8-methylquinolines and azodicarboxylates is described. A cationic rhodium catalyst in the presence of lithium acetate and lithium carbonate was found to be an optimal catalytic system for the construction of quinolin-8-ylmethanamine derivatives, which were evaluated for in vitro cytotoxicity against human breast adenocarcinoma cells (MCF-7) and human prostate adenocarcinoma cells (LNCaP).
PMID: 28956557 [PubMed - as supplied by publisher] (Source: Chemical Communications)
Source: Chemical Communications - September 28, 2017 Category: Chemistry Authors: Jeong T, Kumar Mishra N, Dey P, Oh H, Han S, Hun Lee S, Sik Kim H, Park J, Su Kim I Tags: Chem Commun (Camb) Source Type: research
Novel
Approach for in Situ Recovery of Lithium Carbonate
from Spent Lithium Ion Batteries Using Vacuum Metallurgy
Environmental Science& TechnologyDOI: 10.1021/acs.est.7b02561 (Source: Environmental Science and Technology)
Source: Environmental Science and Technology - September 27, 2017 Category: Environmental Health Authors: managing.editor at est.acs.org (American Chemical Society) Source Type: research
C(sp3)-H amination of 8-methylquinolines with azodicarboxylates under Rh(III) catalysis: cytotoxic evaluation of quinolin-8-ylmethanamines
Chem. Commun., 2017, Accepted Manuscript DOI: 10.1039/C7CC06670H, CommunicationTaejoo Jeong, Neeraj Kumar Mishra, Prasanta Dey, Hyunjung Oh, Sangil Han, Suk Hun Lee, Hyung Sik Kim, Jihye Park, In Su Kim The rhodium(III)-catalyzed C(sp3)-H amination reaction of 8-methylquinolines and azodicarboxylates is described. A cationic rhodium catalyst in the presence of lithium acetate and lithium carbonate was found to be an optimal... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem. Commun. latest articles)
Source: RSC - Chem. Commun. latest articles - September 21, 2017 Category: Chemistry Authors: Taejoo Jeong Source Type: research
The effect of short-term treatment with lithium carbonate on the outcome of radioiodine therapy in patients with long-lasting Graves ’ hyperthyroidism
ConclusionThe short-term treatment with LiCO3 as an adjunct to131I improves efficacy of RIT in patients with long-lasting GH. A success of RIT achieves faster in lithium-treated than in RI group. Treatment with LiCO3 for 7 days prevents transient worsening of hyperthyroidism after RIT. Short-term use of LiCO3 shows no toxic side effects. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - September 11, 2017 Category: Nuclear Medicine Source Type: research
Use of the anion gap and intermittent hemodialysis following continuous hemodiafiltration in extremely high dose acute ‐on‐chronic lithium poisoning: A case report
Abstract
A 35‐year‐old woman intentionally took 40,000 mg of lithium carbonate, and she was transferred to our hospital with nausea, vomiting, and diarrhea. She was diagnosed as having bipolar disorder 10 years ago and was receiving oral lithium therapy. Blood test results on arrival were remarkable for a negative anion gap of −2.1 and later, the serum lithium level turned out to be as high as 15.4 mEq/L. Intubation was required because of disrupted consciousness, and continuous hemodiafiltration (CHDF) was immediately started in the intensive care unit to obtain constant removal of lithium. After adding intermittent...
Source: Hemodialysis International - August 10, 2017 Category: Hematology Authors: Yohei Komaru, Ryota Inokuchi, Yoshihiro Ueda, Masaomi Nangaku, Kent Doi Tags: Case Report Source Type: research
Synthesis and structural characterization of Li3K3Y7(BO3)9
Publication date: September 2017 Source:Journal of Solid State Chemistry, Volume 253 Author(s): Sebastian Bräuchle, Hubert Huppertz Li3K3Y7(BO3)9 was prepared by high-temperature solid state synthesis at 900°C in a platinum crucible from lithium carbonate, potassium carbonate, boric acid, and yttrium(III) oxide. The compound crystallizes in the orthorhombic space group Pca21 (no. 29) (Z = 4). The structure was refined from single-crystal X-ray diffraction data: a = 20.743(8), b = 6.387(4), c = 17.474(4) Å, V = 2315.2(2) Å3, R1 = 0.0473, and wR2 = 0.0637 for all data. The crystal structure of Li3K3Y7(BO3)9 consists ...
Source: Journal of Solid State Chemistry - June 8, 2017 Category: Chemistry Source Type: research
Recycling metals from lithium ion battery by mechanical separation and vacuum metallurgy
This study proposes an integrated process to handle bulk spent lithium manganese (LiMn2O4) batteries to in situ recycle high value-added products without any additives. By mechanical separation, the mixed electrode materials mainly including binder, graphite and LiMn2O4 are firstly obtained from spent batteries. Then, the reaction characteristics for the oxygen-free roasting of mixed electrode materials are analyzed. And the results show that mixed electrode materials can be in situ converted into manganese oxide (MnO) and lithium carbonate (Li2CO3) at 1073K for 45min. In this process, the binder is evaporated and decompos...
Source: Journal of Hazardous Materials - May 23, 2017 Category: Environmental Health Source Type: research
[Profile of lithium carbonate use in patients with bipolar disorder in Colombia].
CONCLUSION: Lithium was generally used at recommended doses and intervals, but a significant percentage of patients received lower doses than those recommended, and it was not possible to compare with lithium levels in blood. Adverse reactions and blood lithium levels reporting should be improved in patients with bipolar disorder in Colombia.
PMID: 28527265 [PubMed - in process] (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - May 21, 2017 Category: International Medicine & Public Health Tags: Biomedica Source Type: research
Decomposing lithium carbonate with a mobile catalyst
Publication date: June 2017 Source:Nano Energy, Volume 36 Author(s): Zixuan Liu, Yantao Zhang, Chuankun Jia, Hao Wan, Zhe Peng, Yujing Bi, Yang Liu, Zhangquan Peng, Qing Wang, Hong Li, Deyu Wang, Ji-Guang Zhang The accumulation of insulating lithium carbonate (Li2CO3) in the air cathode is one of the major obstacles hindering the long-term operation of Li-air batteries. Here two redox mediators (RMs), mononuclear and binuclear cobalt phthalocyanine (mono-CoPc and bi-CoPc), are investigated as mobile catalysts to facilitate decomposition of Li2CO3. Although both RMs possess suitable redox couples at certain po...
Source: Nano Energy - May 4, 2017 Category: Nanotechnology Source Type: research
