Accumulation and neuroprotective effects of lithium on hepatocellular carcinoma mice model
CONCLUSIONS: In summary, lithium can restore the neuronal homeostasis in tumor-bearing mice.PMID:37739227 | DOI:10.1016/j.bbr.2023.114679 (Source: Behavioural Brain Research)
Source: Behavioural Brain Research - September 22, 2023 Category: Neurology Authors: Nataliya Bgatova Natalia Obanina Iuliia Taskaeva Viktoriia Makarova Asel Rakhmetova Svetlana Shatskaya Nikita Khotskin Evgenii Zavjalov Source Type: research

Accumulation and neuroprotective effects of lithium on hepatocellular carcinoma mice model
CONCLUSIONS: In summary, lithium can restore the neuronal homeostasis in tumor-bearing mice.PMID:37739227 | DOI:10.1016/j.bbr.2023.114679 (Source: Brain Research)
Source: Brain Research - September 22, 2023 Category: Neurology Authors: Nataliya Bgatova Natalia Obanina Iuliia Taskaeva Viktoriia Makarova Asel Rakhmetova Svetlana Shatskaya Nikita Khotskin Evgenii Zavjalov Source Type: research

Common changes in rat cortical gene expression after valproate or lithium treatment particularly affect pre- and post-synaptic pathways that regulate four neurotransmitters systems
CONCLUSIONS: Our study suggests that treating with mood stabilisers cause many common changes in levels of RNA which will impact on CNS function, particularly affecting post-synaptic muscarinic receptor functioning and the release of multiple neurotransmitters.PMID:37722808 | DOI:10.1080/15622975.2023.2258972 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - September 18, 2023 Category: Psychiatry Authors: Brian Dean Elizabeth Scarr Source Type: research

Common changes in rat cortical gene expression after valproate or lithium treatment particularly affect pre- and post-synaptic pathways that regulate four neurotransmitters systems
CONCLUSIONS: Our study suggests that treating with mood stabilisers cause many common changes in levels of RNA which will impact on CNS function, particularly affecting post-synaptic muscarinic receptor functioning and the release of multiple neurotransmitters.PMID:37722808 | DOI:10.1080/15622975.2023.2258972 (Source: The World Journal of Biological Psychiatry)
Source: The World Journal of Biological Psychiatry - September 18, 2023 Category: Psychiatry Authors: Brian Dean Elizabeth Scarr Source Type: research

Preliminary results from the Australian Genetics of Bipolar Disorder Study: A nation-wide cohort
CONCLUSION: Our findings highlight the high rate of comorbidities and adverse drug reactions among adults living with bipolar disorder in the general Australian population. Future genomic analyses focus on identifying genetic variants influencing pharmacotherapy treatment response and side effects.PMID:37655588 | DOI:10.1177/00048674231195571 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - September 1, 2023 Category: Psychiatry Authors: Penelope A Lind Dan J Siskind Ian B Hickie Luc ía Colodro-Conde Simone Cross Richard Parker Nicholas G Martin Sarah E Medland Source Type: research

Preliminary results from the Australian Genetics of Bipolar Disorder Study: A nation-wide cohort
CONCLUSION: Our findings highlight the high rate of comorbidities and adverse drug reactions among adults living with bipolar disorder in the general Australian population. Future genomic analyses focus on identifying genetic variants influencing pharmacotherapy treatment response and side effects.PMID:37655588 | DOI:10.1177/00048674231195571 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - September 1, 2023 Category: Psychiatry Authors: Penelope A Lind Dan J Siskind Ian B Hickie Luc ía Colodro-Conde Simone Cross Richard Parker Nicholas G Martin Sarah E Medland Source Type: research

Preliminary results from the Australian Genetics of Bipolar Disorder Study: A nation-wide cohort
CONCLUSION: Our findings highlight the high rate of comorbidities and adverse drug reactions among adults living with bipolar disorder in the general Australian population. Future genomic analyses focus on identifying genetic variants influencing pharmacotherapy treatment response and side effects.PMID:37655588 | DOI:10.1177/00048674231195571 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - September 1, 2023 Category: Psychiatry Authors: Penelope A Lind Dan J Siskind Ian B Hickie Luc ía Colodro-Conde Simone Cross Richard Parker Nicholas G Martin Sarah E Medland Source Type: research

Preliminary results from the Australian Genetics of Bipolar Disorder Study: A nation-wide cohort
CONCLUSION: Our findings highlight the high rate of comorbidities and adverse drug reactions among adults living with bipolar disorder in the general Australian population. Future genomic analyses focus on identifying genetic variants influencing pharmacotherapy treatment response and side effects.PMID:37655588 | DOI:10.1177/00048674231195571 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - September 1, 2023 Category: Psychiatry Authors: Penelope A Lind Dan J Siskind Ian B Hickie Luc ía Colodro-Conde Simone Cross Richard Parker Nicholas G Martin Sarah E Medland Source Type: research

Preliminary results from the Australian Genetics of Bipolar Disorder Study: A nation-wide cohort
CONCLUSION: Our findings highlight the high rate of comorbidities and adverse drug reactions among adults living with bipolar disorder in the general Australian population. Future genomic analyses focus on identifying genetic variants influencing pharmacotherapy treatment response and side effects.PMID:37655588 | DOI:10.1177/00048674231195571 (Source: The Australian and New Zealand Journal of Psychiatry)
Source: The Australian and New Zealand Journal of Psychiatry - September 1, 2023 Category: Psychiatry Authors: Penelope A Lind Dan J Siskind Ian B Hickie Luc ía Colodro-Conde Simone Cross Richard Parker Nicholas G Martin Sarah E Medland Source Type: research

Re-Purposing FDA-Approved Drugs for Opioid Use Disorder
CONCLUSION: These results provide medication options that may be useful in treating OUD as well as integrated therapies to treat comorbid mental illness.PMID:37584436 | DOI:10.1080/10826084.2023.2247071 (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - August 16, 2023 Category: Addiction Authors: Krishna Patel David Waldron Nicholas Graziane Source Type: research

Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring
CONCLUSION: According to the results, prenatal exposure to a high dose of lithium (30 mg/kg) leads to foetal neurodevelopmental disorder and growth restriction through various mechanisms more likely attributed to hypothyroidism, which means it should be either prohibited or prescribed cautiously during pregnancy.PMID:37582655 | DOI:10.1002/jdn.10289 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Samaneh Kakhki Mehrnoush Goodarzi Ali Abbaszade-Cheragheali Mojgan Rajabi Amir Hossein Masoumipour Seyed Reza Khatibi Farimah Beheshti Source Type: research

Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring
CONCLUSION: According to the results, prenatal exposure to a high dose of lithium (30 mg/kg) leads to foetal neurodevelopmental disorder and growth restriction through various mechanisms more likely attributed to hypothyroidism, which means it should be either prohibited or prescribed cautiously during pregnancy.PMID:37582655 | DOI:10.1002/jdn.10289 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Samaneh Kakhki Mehrnoush Goodarzi Ali Abbaszade-Cheragheali Mojgan Rajabi Amir Hossein Masoumipour Seyed Reza Khatibi Farimah Beheshti Source Type: research

Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring
CONCLUSION: According to the results, prenatal exposure to a high dose of lithium (30 mg/kg) leads to foetal neurodevelopmental disorder and growth restriction through various mechanisms more likely attributed to hypothyroidism, which means it should be either prohibited or prescribed cautiously during pregnancy.PMID:37582655 | DOI:10.1002/jdn.10289 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Samaneh Kakhki Mehrnoush Goodarzi Ali Abbaszade-Cheragheali Mojgan Rajabi Amir Hossein Masoumipour Seyed Reza Khatibi Farimah Beheshti Source Type: research

Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring
CONCLUSION: According to the results, prenatal exposure to a high dose of lithium (30 mg/kg) leads to foetal neurodevelopmental disorder and growth restriction through various mechanisms more likely attributed to hypothyroidism, which means it should be either prohibited or prescribed cautiously during pregnancy.PMID:37582655 | DOI:10.1002/jdn.10289 (Source: International Journal of Developmental Neuroscience)
Source: International Journal of Developmental Neuroscience - August 15, 2023 Category: Neuroscience Authors: Samaneh Kakhki Mehrnoush Goodarzi Ali Abbaszade-Cheragheali Mojgan Rajabi Amir Hossein Masoumipour Seyed Reza Khatibi Farimah Beheshti Source Type: research