Toxicities of CAR T-Cell Therapy and the Role of the Consultation-Liaison Psychiatrist
Chimeric antigen receptor (CAR) T-cell therapy is a promising novel T-cell immunotherapy in cancer treatment that has shown clinical efficacy in treating refractory CD19+ B-cell malignancies. However, its use is associated with severe immune-mediated toxicities, including cytokine release syndrome (CRS) and CAR T-cell-related encephalopathy syndrome (CRES). CRS is a systemic inflammatory immune response resulting in symptoms ranging from constitutional to profound organ dysfunction; CRES is a neurotoxicity that can occur concurrently or separately from CRS. (Source: Psychosomatics)
Source: Psychosomatics - November 13, 2018 Category: Psychiatry & Psychology Authors: Deepa Pawar, Jessica Molinaro, Jennifer Knight, Thomas Heinrich Tags: Manuscript ID: Psycho-18-09-0267.R1 Source Type: research

Clinical and toxicological profile of NBOMes: A systematic review
This study aims to aid healthcare professionals in the identification and management of intoxication by NBOMes by reviewing the literature on its clinical manifestations and laboratory detection. (Source: Psychosomatics)
Source: Psychosomatics - November 13, 2018 Category: Psychiatry & Psychology Authors: Nino Cesar Marchi, Juliana Nichterwitz Scherer, Let ícia Schwanck Fara, Lysa Remy, Rafaela Ornel, Monique Reis, Amanda Zamboni, Mariana Paim, Taís Regina Fiorentin, Carlos Alberto Yasin Wayhs, Lisia Von Diemen, Flavio Pechansky, Felix Henrique Paim Kess Tags: Review Article Source Type: research

Behavioral and psychological symptoms in patients with pulmonary hypertension
We read with great interest the article by Aguirre-Camacho and colleagues published in your Journal (1). The authors examined whether pulmonary hypertension patients ’ levels of life satisfaction and optimism may explain the presence of clinically-significant symptoms of depression and anxiety. They also examined the extent to which the presence of clinically-significant symptoms of depression and anxiety may constitute an extra burden to the quality of life ( QoL) of patients. The authors revealed that clinically-significant symptoms of depression and anxiety were only accurately predicted in 50.5% and 56.5% of pati...
Source: Psychosomatics - November 8, 2018 Category: Psychiatry & Psychology Authors: Volkan Do ğan, Cem Çil, Oğuzhan Çelik, Bülent Özlek, Eda Özlek, Aysel Gökçek Tags: Letter to the Editor Source Type: research

Title: Electroconvulsive therapy under oral anticoagulation against deep venous thrombosis in a university hospital setting: Report on eight cases and a review of the literature
We describe challenging instances of ECT implementation while taking direct oral anticoagulants (DOACs). (Source: Psychosomatics)
Source: Psychosomatics - November 7, 2018 Category: Psychiatry & Psychology Authors: Takashi Hirata, Kazuyuki Yasuda, Takuji Uemura, Masataka Ohtsuki, Keita Kobayashi, Tetsuya Ueda, Yu Aruga, Toshio Tamaoki, Takefumi Suzuki Source Type: research

Seizure on the Benzodiazepine Sparing Alcohol Detoxification Protocol: A Case Report
In 2016, approximately 15.1 million people in the United States had an alcohol use disorder (AUD), representing 5.6% of the population.1 The incidence of AUD in medically hospitalized patients is as high as 40%.2 While uncomplicated withdrawal requires minimal treatment, complicated withdrawal involves alcohol hallucinosis, seizures, or delirium tremens (DT) and is a medical emergency.2 The incidence of DT and seizures can be as high as 15% without treatment.3 (Source: Psychosomatics)
Source: Psychosomatics - November 2, 2018 Category: Psychiatry & Psychology Authors: Kathryn Driggers Tags: Case Report Source Type: research

The Prevalence of Mitral Valve Prolapse in Panic Disorder: A Meta-Analysis
Although most studies have suggested that mitral valve prolapse (MVP) is more prevalent in patients with panic disorder (PD) than in healthy controls, there is a substantial uncertainty in the rates of MVP across studies. (Source: Psychosomatics)
Source: Psychosomatics - November 1, 2018 Category: Psychiatry & Psychology Authors: Tural Umit, Iosifescu Dan Tags: Original Research Report Source Type: research

Recognizing and Managing “Magic Wand Syndrome” among Clinical Services
Psychiatry consultation-liaison (C-L) services are occasionally asked to provide an immediate solution to a chronic psychiatric illness or to help stop a persistent pattern of maladaptive behaviors in hospitalized inpatients. When the recommendations by a C-L service falls short of the expectations of consultees, a disruptive dynamic can arise between the two services.1 Our C-L service has colloquially termed this phenomenon “magic wand syndrome” given the inability to wish away problematic issues that can be exhibited by patients. (Source: Psychosomatics)
Source: Psychosomatics - November 1, 2018 Category: Psychiatry & Psychology Authors: Dan H. Nguyen, Thida M. Thant Tags: Letter to the Editor Source Type: research

Postoperative Delirium After Noncardiac Surgery
In this study the authors evaluated 206 patients aged ≥ 60 years for the development of postoperative delirium who underwent noncardiac surgery and were transferred to the surgical intensive care unit. (Source: Psychosomatics)
Source: Psychosomatics - October 30, 2018 Category: Psychiatry & Psychology Authors: Cem Çil, Oğuzhan Çelik, Bülent Özlek, Eda Özlek, Aysel Gökçek, Volkan Doğan Tags: Letter to the Editor Source Type: research

Psychosocial Distress and Health Service Utilization in Patients Undergoing Hemodialysis: A Prospective Study
End-stage renal disease is associated with significant morbidity, high-symptom burden, and health care use. Studies have not yet assessed psychosocial distress and health care utilization in this population. (Source: Psychosomatics)
Source: Psychosomatics - October 9, 2018 Category: Psychiatry & Psychology Authors: Salam El-Majzoub, Istvan Mucsi, Madeline Li, Ghizlane Moussaoui, Mark L. Lipman, Karl J. Looper, Marta Novak, Soham Rej Tags: Original Research Report Source Type: research

Psychosocial Distress and Health Service Utilization in Patients Undergoing Haemodialysis: A Prospective Study
This study examines psychosocial distress and its association with hospitalization and emergency room visits in patients on maintenance haemodialysis. (Source: Psychosomatics)
Source: Psychosomatics - October 9, 2018 Category: Psychiatry & Psychology Authors: Salam El-Majzoub, Istvan Mucsi, Madeline Li, Ghizlane Moussaoui, Mark L. Lipman, Karl J. Looper, Marta Novak, Soham Rej Source Type: research

Deficits in self-reported initiation are associated with subsequent disability in ICU survivors
To determine whether deficits in a key aspect of executive functioning, namely, initiation, were associated with current and future functional disabilities in ICU survivors. (Source: Psychosomatics)
Source: Psychosomatics - September 28, 2018 Category: Psychiatry & Psychology Authors: Jo E. Wilson, Maria C. Duggan, Rameela Chandrasekhar, Nathan E. Brummel, Robert S. Dittus, E. Wesley Ely, Mayur B. Patel, James C. Jackson Source Type: research

Suicide risk screening in pediatric hospitals: Clinical pathways to address a global health crisis
Youth suicide is on the rise worldwide. Most suicide decedents received healthcare services in the year prior to killing themselves. Standardized workflows for suicide risk screening in pediatric hospitals using validated tools can help with timely and appropriate intervention, while attending to The Joint Commission Sentinel Event Alert 56. Here we describe the first attempt to generate clinical pathways (CPs) for patients presenting to pediatric emergency departments (EDs) and inpatient medical settings. (Source: Psychosomatics)
Source: Psychosomatics - September 21, 2018 Category: Psychiatry & Psychology Authors: Khyati Brahmbhatt, Brian P. Kurtz, Khalid I. Afzal, Lisa L. Giles, Elizabeth D. Kowal, Kyle P. Johnson, Elizabeth Lanzillo, Maryland Pao, Sigita Plioplys, Lisa M. Horowitz, PaCC Workgroup Tags: Perspective Source Type: research

Improving the Validity of Nurse-Based Delirium Screening: A Head-to-Head Comparison of Nursing Delirium Screening Scale and Short Confusion Assessment Method
As part of a multicomponent delirium prevention protocol the Confusion Assessment Method (Short-CAM) was introduced to nursing as the standard delirium screening instrument on the general medical units. Despite significant educational efforts, quality monitoring revealed poor sensitivity with the use of Short-CAM. (Source: Psychosomatics)
Source: Psychosomatics - September 12, 2018 Category: Psychiatry & Psychology Authors: Thomas W Heinrich, Hirotaka Kato, Christopher Emanuel, Steven Denson Tags: Original Research Article Source Type: research

The Heart-Brain Connection from a Mental Health Perspective: Interdisciplinary Research & Translational Science Developments
We read with great interest your most recently published meta-analysis review “Treatment of Anxiety in Patients with Coronary Heart Disease: A Systematic Review.”1 The interdisciplinary research between the heart and brain, both from a translational medical science and clinical counseling point of view has recently received much attention. As communicated by the authors, the burden of heart disease is the number one killer in Westernized nations. Furthermore, cardiovascular disease in the United States costs healthcare $317 billion annually, including readmissions due to non-compliance with treatment, psychosoc...
Source: Psychosomatics - September 8, 2018 Category: Psychiatry & Psychology Authors: Anthony Fargnoli, Alyson Pompeo-Fargnoli Tags: -Letter to the Editor Source Type: research

Psychosocial Issues in Pediatric Nonalcoholic Fatty Liver Disease
In recent years, the adoption of unhealthy dietary habits and a sedentary lifestyle has led to an alarming increase in the prevalence of non-alcoholic fatty liver disease (NAFLD) in pediatric populations. Hepatic steatosis is now considered the most common cause of chronic liver disease in children and adolescents and may progress to liver fibrosis and even cirrhosis, increasing long-term mortality rates. Apart from its severe medical co-morbidities, pediatric NAFLD is associated with a variety of psychosocial factors which act either as precipitants or consequences of the disease. (Source: Psychosomatics)
Source: Psychosomatics - September 7, 2018 Category: Psychiatry & Psychology Authors: Katerina Karaivazoglou, Maria Kalogeropoulou, Stelios Assimakopoulos, Christos Triantos Tags: Review Article Source Type: research

Psychosocial issues in pediatric non-alcoholic fatty liver disease
In recent years, the adoption of unhealthy dietary habits and a sedentary lifestyle has led to an alarming increase of non-alcoholic fatty liver disease (NAFLD) prevalence in pediatric populations. Hepatic steatosis is now considered the most common cause of chronic liver disease in children and adolescents and may progress to liver fibrosis and even cirrhosis, increasing long-term mortality rates. Apart from its severe medical co-morbidities, pediatric non-alcoholic fatty liver disease is associated with a variety of psychosocial factors which act either as precipitants or consequences of the disease. (Source: Psychosomatics)
Source: Psychosomatics - September 7, 2018 Category: Psychiatry & Psychology Authors: Karaivazoglou Katerina, Kalogeropoulou Maria, Assimakopoulos Stelios, Triantos Christos Tags: Review Article Source Type: research

Editorial Board
(Source: Psychosomatics)
Source: Psychosomatics - September 1, 2018 Category: Psychiatry & Psychology Source Type: research

Table of Contents
(Source: Psychosomatics)
Source: Psychosomatics - September 1, 2018 Category: Psychiatry & Psychology Source Type: research

Secure Attachment and Depression Predict 6-Month Outcome in Motor Functional Neurological Disorders: A Prospective Pilot Study
The relationships between baseline neuropsychiatric factors and clinical outcome in patients with functional neurological disorder (FND) / conversion disorder remain poorly understood. This prospective, naturalistic pilot study investigated links between predisposing vulnerabilities (risk factors) and clinical outcome in patients with motor FND engaged in usual care within a subspecialty FND clinic. (Source: Psychosomatics)
Source: Psychosomatics - August 29, 2018 Category: Psychiatry & Psychology Authors: Rozita Jalilianhasanpour, Juan Pablo Ospina, Benjamin Williams, Julie Mello, Julie MacLean, Jessica Ranford, Gregory L. Fricchione, W. Curt LaFrance, David L. Perez Source Type: research

Electroconvulsive Therapy, Takotsubo Syndrome, Monitoring of Autonomic Sympathetic Nervous System, and Beta-Blockers
To the Editor: (Source: Psychosomatics)
Source: Psychosomatics - August 28, 2018 Category: Psychiatry & Psychology Authors: John E. Madias Source Type: research

Corrigendum to “The Probability That Catatonia in the Hospital has a Medical Cause and the Relative Proportions of Its Causes: A Systematic Review”
The authors of two studies I cited —references 11 and 17—have kindly requested that their country be cited as “Taiwan” in Table 1. (Source: Psychosomatics)
Source: Psychosomatics - August 22, 2018 Category: Psychiatry & Psychology Authors: Mark A. Oldham Tags: Corrigendum Source Type: research

Pseudocyesis due to chronic constipation and large bowel dilation secondary to a long-standing opioid use disorder – a case report
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Source: Psychosomatics - August 16, 2018 Category: Psychiatry & Psychology Authors: Jay Ching-Chieh Wang, Tamara Mihic, Marie Fennemore Source Type: research

Ramelteon is not associated with improved outcomes among critically ill delirious patients: a single-center retrospective cohort study
Background: Delirium commonly affects critically ill patients and is associated with high morbidity and mortality. Some previous studies have suggested that ramelteon may prevent delirium but ramelteon's impact on treating delirium is unknown.Objective: To compare outcomes of critically ill delirious patients treated with ramelteon versus those who were not.Methods: Retrospective cohort study of 322 intensive care unit patients stratified based on ramelteon exposure after a non-negative CAM-ICU score. (Source: Psychosomatics)
Source: Psychosomatics - August 10, 2018 Category: Psychiatry & Psychology Authors: Robyn Thom, Melissa Bui, Bernard Rosner, Polina Teslyar, Nomi Levy-Carrick, David Wolfe, Michael Klompas Tags: Original Research Article Source Type: research

Trainee Moral Distress in Capacity Consultations for End-of-Life Care
The dilemma of patients ’ capacity to refuse medical care occurs frequently in inpatient settings and often involves a psychiatric consultation (1,2). Though end-of-life decisions are generally considered the realm of palliative care specialists and ethics committees, consultation psychiatrists may play a role in these c omplex situations as well (3). Resolving a clinical dilemma that clearly precipitates withdrawal of treatment and patient death, or which results in additional suffering over a patient's objections, may present a moral burden to the psychiatrist tasked with a consult for capacity to refuse treatment ...
Source: Psychosomatics - August 9, 2018 Category: Psychiatry & Psychology Authors: Caroline S. Bader, Marta D. Herschkopf Source Type: research

Erratum to “Demonstrating conversion in the clinic” [Psychosomatics 58/1 (2017) 97-98]
The publisher would like to inform that the author names were listed and indexed incorrectly.   The correct author names are Richard A. A. Kanaan and Maryam Ejarah Dar. (Source: Psychosomatics)
Source: Psychosomatics - August 7, 2018 Category: Psychiatry & Psychology Authors: Maryam Ejarah Dar, Richard A.A. Kanaan Tags: Erratum Source Type: research

Polyallergy (multiple chemical sensitivity) is associated with excessive healthcare utilization, greater psychotropic use, and greater mental health/functional somatic syndrome disorder diagnoses: a large cohort retrospective study
Associations between the crude capture of polyallergy – also known as multiple chemical sensitivity (MCS) or multiple drug intolerance syndrome (MDIS) – and mental health/functional somatic syndrome disorders, healthcare utilization, or other clinical phenomenon have not been examined extensively. (Source: Psychosomatics)
Source: Psychosomatics - August 2, 2018 Category: Psychiatry & Psychology Authors: Xavier F. Jimenez, Nicole Shirvani, Olivia Hogue, Matt Karafa, George E. Tesar Tags: Original Research Article Source Type: research

Catatonia Following Abrupt Cessation of Oxcarbazepine in a Patient with Prader-Willi Syndrome
Catatonia is poorly understood and underdiagnosed, sometimes with catastrophic consequences. In the past catatonia was associated with schizophrenia, but is currently thought to be a commonly occurring syndrome with a wide range of etiologies.1 While the exact pathophysiology of catatonia remains unknown, because catatonia responds to benzodiazepines and N-methyl-d-aspartate-receptor (NMDA) antagonists,2 abnormalities in gamma aminobutyric acid (GABA) and glutamate signaling have been suggested as a likely mechanism, as well as dopamine due to its relationship with NMDA and GABA. (Source: Psychosomatics)
Source: Psychosomatics - July 30, 2018 Category: Psychiatry & Psychology Authors: Samantha Zwiebel, Abner O. Rayapati, Jose de Leon Tags: Original Research Article Source Type: research

Catatonia Due to Clozapine Withdrawal: A Case Report and Literature Review
Catatonia is a neuropsychiatric syndrome defined by the DSM-5 as a combination of 3 or more of 12 signs or symptoms, including echopraxia, echolalia, catalepsy, stupor, negativism, waxy flexibility, mutism, posturing, mannerisms, stereotypy, grimacing, and agitation.1 The syndrome has been linked to various etiologies, including bipolar illness, depression, psychotic illness, autism, and medical etiologies (including seizure disorders, autoimmune disorders, and encephalopathies).2,3 Catatonia is relatively common, with the prevalence of the syndrome among psychiatric inpatients ranging from 7% to 18%. (Source: Psychosomatics)
Source: Psychosomatics - July 28, 2018 Category: Psychiatry & Psychology Authors: Mina Boazak, Robert O. Cotes, Hannah Potvin, Ann Marie Decker, Ann C. Schwartz Tags: Case Report Source Type: research

Catatonia due to clozapine withdrawal: A case report and synthesis of the literature
The treatment of catatonia for patients experiencing psychosis poses unique challenges to the clinician, specifically around whether to restart or withhold an antipsychotic. Antipsychotics have been implicated in the worsening and improvement of catatonia. The management of catatonia in the context of clozapine withdrawal is an area where the literature is sparse and there is little guidance. (Source: Psychosomatics)
Source: Psychosomatics - July 28, 2018 Category: Psychiatry & Psychology Authors: Mina Boazak, Robert O. Cotes, Hannah Potvin, Ann Marie Decker, Ann C. Schwartz Tags: Case Report Source Type: research

The Prevalence of Post-Traumatic Stress Disorder Symptoms in Chronic Pain Patients in a Tertiary Care Setting: A Cross-sectional Study
There is limited research published regarding the prevalence of PTSD in a large civilian multidisciplinary pain clinic setting. Controlled studies have been performed in the US, but have only examined specific patient populations such as post-motor vehicle accidents, war veterans, work-related injuries, back pain, and headache. The purpose of this study was to estimate the prevalence of Post-Traumatic Stress Disorder (PTSD) symptoms in the chronic pain population at a large multidisciplinary pain clinic. (Source: Psychosomatics)
Source: Psychosomatics - July 28, 2018 Category: Psychiatry & Psychology Authors: Eeman Akhtar, Angela Ballew, Walter N. Orr, Angela Mayorga, Talal W. Khan Tags: Original Research Article Source Type: research

Tardive Dyskinesia Suppression Seen During Catatonic State: A Case Report
A 53 year old female with a history of schizophrenia and tardive dyskinesia presented with catatonia following several weeks of disorganized behavior and delusional beliefs. According to history obtained by family, her schizophrenia had been successfully treated for approximately 30 years with clozapine. Upon admission, the patient had no physical signs of tardive dyskinesia or extrapyramidal symptoms (EPS). With the administration of lorazepam over the next few days, the patient's catatonia improved greatly. (Source: Psychosomatics)
Source: Psychosomatics - July 28, 2018 Category: Psychiatry & Psychology Authors: Aaron Pierce, Douglas Coker Tags: Case Report Source Type: research

Thirty years of both ignorance and clinical experience suggest that clozapine intoxication during co-occurring infections and inflammation may have higher morbidity and mortality than is currently believed
We1 previously described a massive increase in clozapine serum concentrations during pneumonia. Based on that case, prior published cases, and our clinical experience, we recommended that for clozapine patients with severe infections or inflammations, the clinician order clozapine therapeutic drug monitoring (TDM) and, when TDM is not possible, consider cutting the clozapine dose in half. Leung2 provided an intelligent commentary on our case. We only disagree with two of his statements: 1) a dose reduction by half may not be appropriate for all patients with infection, especially in the absence of adverse drug reactions (A...
Source: Psychosomatics - July 25, 2018 Category: Psychiatry & Psychology Authors: Can-Jun Ruan, Jose de Leon Tags: Letter to the Editor Source Type: research

Hospital length of stay with a proactive psychiatric consultation model in the medical intensive care unit: a prospective cohort analysis
Previous studies have demonstrated that proactive psychiatric consultation reduces hospital length of stay (LOS) in the general medical setting, however this model has not been studied in intensive care units (ICU). (Source: Psychosomatics)
Source: Psychosomatics - July 25, 2018 Category: Psychiatry & Psychology Authors: Melissa Bui, Robyn P. Thom, Shelley Hurwitz, Nomi C. Levy-Carrick, Molly O'Reilly, Dara Wilensky, Daniel Talmasov, Bonnie Blanchfield, Vineeta Vaidya, Rose Kakoza, Michael Klompas, Elizabeth Stanley, David Gitlin, Anthony Massaro Tags: Original Research Article Source Type: research

A survey of clinical approaches to suicide risk assessment for patients intoxicated on alcohol
This study aims to describe practice patterns among expert practitioners for timing the suicide risk assessment for an intoxicated patient. (Source: Psychosomatics)
Source: Psychosomatics - July 23, 2018 Category: Psychiatry & Psychology Authors: Scott A. Simpson Tags: Original research article Source Type: research

Autoimmune Encephalopathy Beyond Anti-NMDAR Encephalitis: The Case of an Adolescent Male with AntiAcetylcholine Receptor Ganglionic Neuronal Antibody Encephalitis
Autoimmune encephalitis is an increasingly recognized disease process in the differential assessment of youth presenting with acute altered mental status or psychosis. Much of the recent evidence relating to autoimmune encephalitis in the past 10 years relates to anti-N-methyl D-aspartate receptor (anti-NMDAR) encephalitis. Anti-NMDAR encephalitis was first reported by Dalmau et al. in 2007 and is the most common noninfectious cause of encephalitis.1,2 However, there are other less common causes of autoimmune encephalitis that are important to consider in the differential of acute altered mental status in youth. (Source: Psychosomatics)
Source: Psychosomatics - July 20, 2018 Category: Psychiatry & Psychology Authors: Ferdnand C. Osuagwu, Sarah S. Mohiuddin, Nasuh Malas Tags: Case Report Source Type: research

The neuroanatomy of Somatoform Disorders: a Magnetic Resonance Imaging study
Somatoform Disorders (SD) are a heterogeneous group of psychiatric syndromes characterized by common symptoms, which may mimic a physical condition but they are not explained by a medical condition. Although the biological nature of this disorder has been widely accepted, the neuroanatomical correlates characterizing SD are still inconclusive. Therefore, this study aims to explore GM volume alterations in SD patients compared to HC and their possible association with clinical and cognitive measures. (Source: Psychosomatics)
Source: Psychosomatics - July 20, 2018 Category: Psychiatry & Psychology Authors: G Delvecchio, MG Rossetti, E Caletti, A Arighi, D Galimberti, P Basilico, M Mercurio, RA Paoli, C Cinnante, F Triulzi, AC Altamura, E Scarpini, P Brambilla Tags: Original Research Article Source Type: research

Autoimmune Encephalopathy Beyond Anti-NMDAR Encephalitis: The Case of an Adolescent Male with Anti-Acetylcholine Receptor Ganglionic Neuronal Antibody Encephalitis
Since the discovery of anti-N-Methyl D-Aspartate Receptor (anti-NMDAR) encephalitis in 2007, there has been a growing awareness of autoimmune encephalitis as a diagnostic consideration in the patient presenting with altered mental status. Anti-acetylcholine receptor ganglionic neuronal antibody (Anti-AchR GN Ab) encephalitis is a rare cause of autoimmune encephalitis only previously reported in a large epidemiologic study of an adult cohort. It is characterized with prominent dysautonomia and rarely considered in the differential of autoimmune encephalitis, particularly in youth. (Source: Psychosomatics)
Source: Psychosomatics - July 20, 2018 Category: Psychiatry & Psychology Authors: Ferdnand C. Osuagwu, Sarah S. Mohiuddin, Nasuh Malas Tags: Case Report Source Type: research

A New Measure of Health Numeracy: Brief Medical Numbers Test (BMNT)
Approximately half of Americans have inadequate health literacy, which leads to poorer health outcomes. Health numeracy is an important component of literacy, which reflects one's ability to understand and manipulate numbers. This is especially important for transplant candidates, as adherence to medical recommendations is essential for post-transplant care. Although validated measures of numeracy exist, they can be inconvenient and timely to administer. (Source: Psychosomatics)
Source: Psychosomatics - July 19, 2018 Category: Psychiatry & Psychology Authors: Kate E. Dykhuis, Linda Slowik, Kelly Bryce, Maren E. Hyde-Nolan, Anne Eshelman, Lisa Renee Miller-Matero Tags: Original Research Article Source Type: research

Tianeptine Abuse and Dependence: Case Report and Literature Review
Tianeptine (Stablon, Coaxil) abuse and dependence has become increasingly prominent worldwide with recent presence in the United States. However, no comprehensive review of cases has been conducted focusing on acute presentation to fatal intoxication and methods of management. In this article, we add a case to the growing literature on tianeptine dependence, the first of which is concerning for the presence of an adulterant, and present a comprehensive literature review. (Source: Psychosomatics)
Source: Psychosomatics - July 19, 2018 Category: Psychiatry & Psychology Authors: Rahul Lauhan, Alan Hsu, Al Alam, Kristin Beizai Tags: Review Article Source Type: research

The 2018 ISHLT/APM/AST/ICCAC/STSW recommendations for the psychosocial evaluation of adult cardiothoracic transplant candidates and candidates for long-term mechanical circulatory support
The psychosocial evaluation is well-recognized as an important component of the multifaceted assessment process to determine candidacy for heart transplantation, lung transplantation, and long-term mechanical circulatory support (MCS). However, there is no consensus-based set of recommendations for either the full range of psychosocial domains to be assessed during the evaluation, or the set of processes and procedures to be used to conduct the evaluation, report its findings, and monitor patients ’ receipt of and response to interventions for any problems identified. (Source: Psychosomatics)
Source: Psychosomatics - July 10, 2018 Category: Psychiatry & Psychology Authors: Mary Amanda Dew, Andrea F. DiMartini, Fabienne Dobbels, Kathleen L. Grady, Sheila G. Jowsey-Gregoire, Annemarie Kaan, Kay Kendall, Quincy-Robyn Young, Susan E. Abbey, Zeeshan Butt, Catherine C. Crone, Sabina De Geest, Christina T. Doligalski, Christiane K Tags: Editorial Source Type: research

Title
(Source: Psychosomatics)
Source: Psychosomatics - July 10, 2018 Category: Psychiatry & Psychology Authors: author name Tags: Original Research Article Source Type: research

Severe aggression after perampanel overdose: case report
Perampanel (PER) is a non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonist, first in its pharmacologic class to be proposed as an anticonvulsant. As a relatively new agent, systematic reviews and reports on this drug's benefits and adverse effects are still quite limited. This is the first case report of PER overdose in a patient without a previously documented history of seizure disorder or existing prescription of PER, and it is the second case report of any PER overdose. (Source: Psychosomatics)
Source: Psychosomatics - July 10, 2018 Category: Psychiatry & Psychology Authors: Carrie C. Wu, Michael McShane, Eileen A. Huttlin, Kenneth C. Novoa Tags: Case Report Source Type: research

Clozapine-Associated Aspiration Pneumonia: Case Series and Review of the Literature: Reply
We read with interest the recent report by Dr. Jonathan Kaplan and colleagues,1 in which they describe 2 patients who developed aspiration pneumonia in the context of clozapine initiation. They rightly underscore the need for clinicians to be alert to the increased risk of pneumonia with the use of antipsychotic medications, especially second generation agents, and review emerging evidence that aspiration pneumonia in particular is a potential complication of treatment with clozapine. In addition to their own cases, they identified 4 prior reports of clozapine-associated pneumonia in which aspiration was strongly implicate...
Source: Psychosomatics - July 9, 2018 Category: Psychiatry & Psychology Authors: Ronald J. Gurrera, Nicole L. Perry Tags: Letter to the Editor Source Type: research

Clozapine-Associated Aspiration Pneumonia: Case Series and Review of the Literature. Reply
We read with interest the recent report by Dr. Jonathan Kaplan and colleagues,1 in which they describe 2 patients who developed aspiration pneumonia in the context of clozapine initiation. They rightly underscore the need for clinicians to be alert to the increased risk of pneumonia with the use of antipsychotic medications, especially second generation agents, and review emerging evidence that aspiration pneumonia in particular is a potential complication of treatment with clozapine. In addition to their own cases, they identified 4 prior reports of clozapine-associated pneumonia in which aspiration was strongly implicate...
Source: Psychosomatics - July 9, 2018 Category: Psychiatry & Psychology Authors: Ronald J. Gurrera, Nicole L. Perry Tags: Letter to the Editor Source Type: research

Low plasma cholinesterase activity is associated with postoperative delirium after noncardiac surgery in elderly patients: A prospective observational study
Postoperative delirium (POD) commonly occurs in elderly patients after noncardiac surgery, resulting in increased morbidity and greater risk of death. However, its pathophysiology is currently unknown. Cholinergic dysfunction has been implicated in delirium pathophysiology, and low plasma cholinesterase activity has been reported as a risk marker of POD. Therefore, the aim of this study was to investigate the link between plasma cholinesterase activity and POD in elderly Han Chinese patients after noncardiac surgery. (Source: Psychosomatics)
Source: Psychosomatics - July 9, 2018 Category: Psychiatry & Psychology Authors: Bao Zhao, Yuhua Ni, Xingsong Tian Tags: Original Research Article Source Type: research

Psychiatric Consultation of the Incarcerated Patient: Clinical Presentations and Management
Consultation liaison psychiatrists are likely to encounter incarcerated patients due to high prevalence of mental illness among this population and limited mental health resources in jails and prisons. At our tertiary care teaching hospital we have performed nearly 800 consultations on inmates over the previous 8 years.Method: A descriptive case report is presented of Mr. B, a 25 year old male, transferred from jail with attempted self-enucleation and psychotic symptoms. A brief review of literature regarding psychiatric care of incarcerated patients is included, as well as a how we worked with correctional staff to manage...
Source: Psychosomatics - July 4, 2018 Category: Psychiatry & Psychology Authors: Sara Puening, Philippe Weintraub, Thomas M. Dunn Tags: Case Report Source Type: research

Serotonin toxicity and urinary analgesics: a case report and systematic literature review of methylene blue-induced serotonin syndrome
Serotonin syndrome (SS) is a rare, but potentially life-threatening, condition resulting from the use of serotonergic drugs.1,2 Symptoms can range from mild to severe and classically consist of altered mental status, autonomic instability and neuromuscular excitation. Specific symptoms include fever, tremor, diaphoresis, altered mental status including confusion or agitation, clonus, hyperrelxia and hypertonia. Fatalities have been reported.3 (Source: Psychosomatics)
Source: Psychosomatics - July 3, 2018 Category: Psychiatry & Psychology Authors: Zachary Zuschlag, Matthew Warren, Susan Schultz Tags: Review article Source Type: research

Psychosocial Predictors of Cognition in Bariatric Surgery
Obesity affects individuals worldwide and is currently the 5th leading cause of death according to the WHO. Bariatric surgery is an effective strategy that produces durable long-term weight loss. There is a bidirectional interplay between mental health and obesity; with higher depression and anxiety in the obese population as well as significant effects on weight loss for people with mental health disorders. Our cross-sectional study aims to examine psychosocial predictors of cognition for the pre-operative bariatric surgery population and its effect on work productivity. (Source: Psychosomatics)
Source: Psychosomatics - July 2, 2018 Category: Psychiatry & Psychology Authors: Mario Moscovici, Susan Wnuk, Allan Okrainec, Raed Hawa, Sanjeev Sockalingam Tags: Original Research Article Source Type: research

Limb Self-Amputation Without Replantation: A Case Report and Management Considerations
Major self-mutilation describes severe acts of harm to oneself, generally leading to permanent damage and loss of function in the absence of suicidal intent. The most common presentations include limb amputation, genital amputation, or auto-enucleation. Coordination of care is multidisciplinary with psychiatrists playing a pivotal role. Little literature is available with respect to managing care of patients who do not undergo replantation of a self-amputated limb. (Source: Psychosomatics)
Source: Psychosomatics - July 2, 2018 Category: Psychiatry & Psychology Authors: Jack Van Bezooyen, Elon E. Richman, Cody M. Browning, Ann C. Schwartz, Robert O. Cotes Tags: Original Research Article Source Type: research

Catatonia Associated With Systemic Lupus Erythematosus (SLE): A Report of 2 Cases and a Review of the Literature
Systemic lupus erythematosus (SLE) is known to cause neuropsychiatric symptoms (NPSLE). While not formally recognized as a syndrome associated with NPSLE, catatonia has frequently been reported. (Source: Psychosomatics)
Source: Psychosomatics - June 27, 2018 Category: Psychiatry & Psychology Authors: Annabel Boeke, Bianca Pullen, Lucas Coppes, Michel Medina, Joseph J Cooper Tags: Review Article Source Type: research