Toxicities of CAR T-Cell Therapy and the Role of the Consultation-Liaison Psychiatrist
Chimeric antigen receptor (CAR) T-cell therapy is a promising novel T-cell immunotherapy in cancer treatment that has shown clinical efficacy in treating refractory CD19+ B-cell malignancies. However, its use is associated with severe immune-mediated toxicities, including cytokine release syndrome (CRS) and CAR T-cell-related encephalopathy syndrome (CRES). CRS is a systemic inflammatory immune response resulting in symptoms ranging from constitutional to profound organ dysfunction; CRES is a neurotoxicity that can occur concurrently or separately from CRS. (Source: Psychosomatics)
Source: Psychosomatics - November 13, 2018 Category: Psychiatry & Psychology Authors: Deepa Pawar, Jessica Molinaro, Jennifer Knight, Thomas Heinrich Tags: Manuscript ID: Psycho-18-09-0267.R1 Source Type: research
Clinical and toxicological profile of NBOMes: A systematic review
This study aims to aid healthcare professionals in the identification and management of intoxication by NBOMes by reviewing the literature on its clinical manifestations and laboratory detection. (Source: Psychosomatics)
Source: Psychosomatics - November 13, 2018 Category: Psychiatry & Psychology Authors: Nino Cesar Marchi, Juliana Nichterwitz Scherer, Let ícia Schwanck Fara, Lysa Remy, Rafaela Ornel, Monique Reis, Amanda Zamboni, Mariana Paim, Taís Regina Fiorentin, Carlos Alberto Yasin Wayhs, Lisia Von Diemen, Flavio Pechansky, Felix Henrique Paim Kess Tags: Review Article Source Type: research
Behavioral and psychological symptoms in patients with pulmonary hypertension
We read with great interest the article by Aguirre-Camacho and colleagues published in your Journal (1). The authors examined whether pulmonary hypertension patients ’ levels of life satisfaction and optimism may explain the presence of clinically-significant symptoms of depression and anxiety. They also examined the extent to which the presence of clinically-significant symptoms of depression and anxiety may constitute an extra burden to the quality of life ( QoL) of patients. The authors revealed that clinically-significant symptoms of depression and anxiety were only accurately predicted in 50.5% and 56.5% of patients...
Source: Psychosomatics - November 8, 2018 Category: Psychiatry & Psychology Authors: Volkan Do ğan, Cem Çil, Oğuzhan Çelik, Bülent Özlek, Eda Özlek, Aysel Gökçek Tags: Letter to the Editor Source Type: research
Title: Electroconvulsive therapy under oral anticoagulation against deep venous thrombosis in a university hospital setting: Report on eight cases and a review of the literature
We describe challenging instances of ECT implementation while taking direct oral anticoagulants (DOACs). (Source: Psychosomatics)
Source: Psychosomatics - November 7, 2018 Category: Psychiatry & Psychology Authors: Takashi Hirata, Kazuyuki Yasuda, Takuji Uemura, Masataka Ohtsuki, Keita Kobayashi, Tetsuya Ueda, Yu Aruga, Toshio Tamaoki, Takefumi Suzuki Source Type: research
Seizure on the Benzodiazepine Sparing Alcohol Detoxification Protocol: A Case Report
In 2016, approximately 15.1 million people in the United States had an alcohol use disorder (AUD), representing 5.6% of the population.1 The incidence of AUD in medically hospitalized patients is as high as 40%.2 While uncomplicated withdrawal requires minimal treatment, complicated withdrawal involves alcohol hallucinosis, seizures, or delirium tremens (DT) and is a medical emergency.2 The incidence of DT and seizures can be as high as 15% without treatment.3 (Source: Psychosomatics)
Source: Psychosomatics - November 2, 2018 Category: Psychiatry & Psychology Authors: Kathryn Driggers Tags: Case Report Source Type: research
The Prevalence of Mitral Valve Prolapse in Panic Disorder: A Meta-Analysis
Although most studies have suggested that mitral valve prolapse (MVP) is more prevalent in patients with panic disorder (PD) than in healthy controls, there is a substantial uncertainty in the rates of MVP across studies. (Source: Psychosomatics)
Source: Psychosomatics - November 1, 2018 Category: Psychiatry & Psychology Authors: Tural Umit, Iosifescu Dan Tags: Original Research Report Source Type: research
Recognizing and Managing “Magic Wand Syndrome” among Clinical Services
Psychiatry consultation-liaison (C-L) services are occasionally asked to provide an immediate solution to a chronic psychiatric illness or to help stop a persistent pattern of maladaptive behaviors in hospitalized inpatients. When the recommendations by a C-L service falls short of the expectations of consultees, a disruptive dynamic can arise between the two services.1 Our C-L service has colloquially termed this phenomenon “magic wand syndrome” given the inability to wish away problematic issues that can be exhibited by patients. (Source: Psychosomatics)
Source: Psychosomatics - November 1, 2018 Category: Psychiatry & Psychology Authors: Dan H. Nguyen, Thida M. Thant Tags: Letter to the Editor Source Type: research
Postoperative Delirium After Noncardiac Surgery
In this study the authors evaluated 206 patients aged ≥ 60 years for the development of postoperative delirium who underwent noncardiac surgery and were transferred to the surgical intensive care unit. (Source: Psychosomatics)
Source: Psychosomatics - October 30, 2018 Category: Psychiatry & Psychology Authors: Cem Çil, Oğuzhan Çelik, Bülent Özlek, Eda Özlek, Aysel Gökçek, Volkan Doğan Tags: Letter to the Editor Source Type: research
Psychosocial Distress and Health Service Utilization in Patients Undergoing Hemodialysis: A Prospective Study
End-stage renal disease is associated with significant morbidity, high-symptom burden, and health care use. Studies have not yet assessed psychosocial distress and health care utilization in this population. (Source: Psychosomatics)
Source: Psychosomatics - October 9, 2018 Category: Psychiatry & Psychology Authors: Salam El-Majzoub, Istvan Mucsi, Madeline Li, Ghizlane Moussaoui, Mark L. Lipman, Karl J. Looper, Marta Novak, Soham Rej Tags: Original Research Report Source Type: research
Psychosocial Distress and Health Service Utilization in Patients Undergoing Haemodialysis: A Prospective Study
This study examines psychosocial distress and its association with hospitalization and emergency room visits in patients on maintenance haemodialysis. (Source: Psychosomatics)
Source: Psychosomatics - October 9, 2018 Category: Psychiatry & Psychology Authors: Salam El-Majzoub, Istvan Mucsi, Madeline Li, Ghizlane Moussaoui, Mark L. Lipman, Karl J. Looper, Marta Novak, Soham Rej Source Type: research
Deficits in self-reported initiation are associated with subsequent disability in ICU survivors
To determine whether deficits in a key aspect of executive functioning, namely, initiation, were associated with current and future functional disabilities in ICU survivors. (Source: Psychosomatics)
Source: Psychosomatics - September 28, 2018 Category: Psychiatry & Psychology Authors: Jo E. Wilson, Maria C. Duggan, Rameela Chandrasekhar, Nathan E. Brummel, Robert S. Dittus, E. Wesley Ely, Mayur B. Patel, James C. Jackson Source Type: research
Suicide risk screening in pediatric hospitals: Clinical pathways to address a global health crisis
Youth suicide is on the rise worldwide. Most suicide decedents received healthcare services in the year prior to killing themselves. Standardized workflows for suicide risk screening in pediatric hospitals using validated tools can help with timely and appropriate intervention, while attending to The Joint Commission Sentinel Event Alert 56. Here we describe the first attempt to generate clinical pathways (CPs) for patients presenting to pediatric emergency departments (EDs) and inpatient medical settings. (Source: Psychosomatics)
Source: Psychosomatics - September 21, 2018 Category: Psychiatry & Psychology Authors: Khyati Brahmbhatt, Brian P. Kurtz, Khalid I. Afzal, Lisa L. Giles, Elizabeth D. Kowal, Kyle P. Johnson, Elizabeth Lanzillo, Maryland Pao, Sigita Plioplys, Lisa M. Horowitz, PaCC Workgroup Tags: Perspective Source Type: research
Improving the Validity of Nurse-Based Delirium Screening: A Head-to-Head Comparison of Nursing Delirium Screening Scale and Short Confusion Assessment Method
As part of a multicomponent delirium prevention protocol the Confusion Assessment Method (Short-CAM) was introduced to nursing as the standard delirium screening instrument on the general medical units. Despite significant educational efforts, quality monitoring revealed poor sensitivity with the use of Short-CAM. (Source: Psychosomatics)
Source: Psychosomatics - September 12, 2018 Category: Psychiatry & Psychology Authors: Thomas W Heinrich, Hirotaka Kato, Christopher Emanuel, Steven Denson Tags: Original Research Article Source Type: research
The Heart-Brain Connection from a Mental Health Perspective: Interdisciplinary Research & Translational Science Developments
We read with great interest your most recently published meta-analysis review “Treatment of Anxiety in Patients with Coronary Heart Disease: A Systematic Review.”1 The interdisciplinary research between the heart and brain, both from a translational medical science and clinical counseling point of view has recently received much attention. As communicated by the authors, the burden of heart disease is the number one killer in Westernized nations. Furthermore, cardiovascular disease in the United States costs healthcare $317 billion annually, including readmissions due to non-compliance with treatment, psychosocial and ...
Source: Psychosomatics - September 8, 2018 Category: Psychiatry & Psychology Authors: Anthony Fargnoli, Alyson Pompeo-Fargnoli Tags: -Letter to the Editor Source Type: research
Psychosocial Issues in Pediatric Nonalcoholic Fatty Liver Disease
In recent years, the adoption of unhealthy dietary habits and a sedentary lifestyle has led to an alarming increase in the prevalence of non-alcoholic fatty liver disease (NAFLD) in pediatric populations. Hepatic steatosis is now considered the most common cause of chronic liver disease in children and adolescents and may progress to liver fibrosis and even cirrhosis, increasing long-term mortality rates. Apart from its severe medical co-morbidities, pediatric NAFLD is associated with a variety of psychosocial factors which act either as precipitants or consequences of the disease. (Source: Psychosomatics)
Source: Psychosomatics - September 7, 2018 Category: Psychiatry & Psychology Authors: Katerina Karaivazoglou, Maria Kalogeropoulou, Stelios Assimakopoulos, Christos Triantos Tags: Review Article Source Type: research
