[ASAP] Yttrium Manganese Oxide Phase Stability and Selectivity Using Lithium Carbonate Assisted Metathesis Reactions
Inorganic ChemistryDOI: 10.1021/acs.inorgchem.9b02075 (Source: Inorganic Chemistry)
Source: Inorganic Chemistry - November 4, 2019 Category: Chemistry Authors: Paul K. Todd, Antoinette M. M. Smith, and James R. Neilson* Source Type: research

Cytological Characteristics of a Heterogeneous Population of Hepatocellular Carcinoma-29 Cells after Injection of Lithium Carbonate in the Experiment
Five cytological types of hepatocellular carcinoma-29 (G-29) grown in the muscle tissue of the thigh of experimental animals were identified by transmission electron microscopy; 89% of these were poorly differentiated type I-III cells. Lithium in a concentration of 20 mM produced a damaging effect on poorly differentiated G-29 cells: the number of cells with zones of intracellular component destruction and volume density of these zones increased, while volume density of cisterns of endoplasmic reticulum decreased. These results suggest that lithium carbonate can cause destructive changes in the heterogeneous population of ...
Source: Bulletin of Experimental Biology and Medicine - October 25, 2019 Category: Biology Source Type: research

Combination of Olanzapine and Samidorphan Has No Clinically Significant Effect on the Pharmacokinetics of Lithium or Valproate
ConclusionsConsistent with previously reported findings on olanzapine, administration of multiple doses of OLZ/SAM did not have a clinically significant effect on the pharmacokinetics of lithium or valproate. Co-administration of OLZ/SAM and lithium or valproate was generally well tolerated; the safety profile of OLZ/SAM was consistent with that observed in previous clinical studies. (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - October 3, 2019 Category: Drugs & Pharmacology Source Type: research

[ASAP] Crystallization of Lithium Carbonate from Aqueous Solution: New Insights into Crystal Agglomeration
Industrial& Engineering Chemistry ResearchDOI: 10.1021/acs.iecr.9b03644 (Source: Industrial and Engineering Chemical Research)
Source: Industrial and Engineering Chemical Research - September 18, 2019 Category: Chemistry Authors: Wenchao Yang †, Ling Zhou*†, Jiayu Dai†, Lina Zhou†‡, Meijing Zhang†‡, Chuang Xie†‡, Hongxun Hao†‡, Baohong Hou†‡, Ying Bao†‡, and Qiuxiang Yin*†‡ Source Type: research

Kinetic analysis of lithium–titanium ferrite formation from mechanically milled reagents
In this study, the AGO-2S planetary ball mill was used for mechanical milling of the initial reagents. The X-ray diffraction patterns for mechanically activated mixtures show increased of the width intensities of reflections due to decreased crystallite size which caused by mechanical grinding. Thermal analysis showed that the reaction of lithium-titanium ferrite synthesis proceeds in two stages. For the initial mixture (non-milled), mass reduces within the temperature range of 430–720 °C. The results obtained for mechanically activated samples show that mass reduction in these samples begins at much lower temperature...
Source: Materials Chemistry and Physics - August 27, 2019 Category: Materials Science Source Type: research

Propylthiouracil-induced agranulocytosis as a rare complication of antithyroid drugs in a patient with Graves’ disease
CONCLUSION: Thionamide-induced agranulocytosis is a rare complication. With a contraindication to ATDs, RAI and surgery are definitive therapeutic options in GD. Beta-blockers, glucocorticoids, lithium carbonate, iodine, and cholestyramine may be an adjunctive therapy for hyperthyroidism.RESUMO INTRODU ÇÃO: A doença de Graves (DG) é uma doença autoimune caracterizada por hipertireoidismo. As drogas antitireoidianas (DAT) são opções terapêuticas disponíveis. A agranulocitose é uma complicação rara, potencialmente fatal desta terapia. Neste estudo, relatamos um caso de agranulocitose in duzida por propiltiourac...
Source: Revista da Associacao Medica Brasileira - July 23, 2019 Category: General Medicine Source Type: research

Recommendations of the Polish Psychiatric Association regarding the treatment of affective disorders in women of childbearing age. Part II: Bipolar disorder.
Authors: Rybakowski J, Cubała WJ, Gałecki P, Rymaszewska J, Samochowiec J, Szulc A, Dudek D Abstract In the article, the recommendations of the Polish Psychiatric Association regarding pharmacological treatment of women with bipolar disorder during pregnancy and postpartum period were presented. The issue pertains to every twentieth woman wanting to get pregnant. Before planned pregnancy, it is advisable to obtain a several-month stabilization of psychiatric state, to establish treatment with one mood-stabilizing drug (except for valproate and carbamazepine) or gradual discontinuation of drugs in case of...
Source: Psychiatria Polska - July 19, 2019 Category: Psychiatry Tags: Psychiatr Pol Source Type: research

Revisiting Lithium: Utility for Behavioral Stabilization in Adolescents and Adults with Autism Spectrum Disorder.
Conclusions: Lithium carbonate is a viable, efficacious and well tolerated alternative to various neuroleptics and other psychotropic medications for use as a mood stabilizer for patients with ASD. PMID: 31308580 [PubMed - in process] (Source: Psychopharmacology Bulletin)
Source: Psychopharmacology Bulletin - July 18, 2019 Category: Psychiatry & Psychology Tags: Psychopharmacol Bull Source Type: research

Ultrastructural Changes in Hepatocellular Carcinoma-29 Cells after Treatment with Lithium Carbonate
We studied the effect of lithium carbonate on hepatocellular carcinoma-29 cells in CBA male mice after injection in a dose of 20 mM along the tumor periphery. Transmission electron microscopy revealed a decrease in the volume density of the granular endoplasmic reticulum in the cell cytoplasm and an increase in the total numerical and volume density of autophagosomes and autolysosomes and zones of destruction of intracellular organelles. The ability of lithium carbonate to activate intracellular degradation processes in tumor cells and to stimulate cell death can be used to develop new combined strategies in the chemothera...
Source: Bulletin of Experimental Biology and Medicine - June 7, 2019 Category: Biology Source Type: research

Battery grade lithium produced following successful first pilot test
Publication date: May 2019Source: Membrane Technology, Volume 2019, Issue 5Author(s): Canada's Saltworks Technologies is helping Standard Lithium – a speciality chemical company that focuses on unlocking the value of existing large-scale US-based lithium-bearing brine resources – to produce high-purity lithium carbonate. (Source: Membrane Technology)
Source: Membrane Technology - May 23, 2019 Category: Materials Science Source Type: research

Mechanically stimulated thermal synthesis of lithium aluminates
Publication date: 2019Source: Materials Today: Proceedings, Volume 12, Part 1Author(s): V.P. Isupov, I.A. Borodulina, N.V. Eremina, N.V. BulinaAbstractThe influence of the conditions of preliminary mechanical activation of a mixture of gibbsite and lithium carbonate in a planetary-type activator and the conditions of subsequent heat treatment on the phase composition of lithium aluminates is studied. It is shown that for the formation of γ-LiAlO2 it is necessary that at the stage of mechanical activation of the mixture an almost complete amorphization of aluminum hydroxide occurs, and the air heat treatment is carried out...
Source: Materials Today: Proceedings - May 21, 2019 Category: Materials Science Source Type: research

Finding the best effective way of treatment for rapid I-131 turnover Graves’ disease patients: A randomized clinical trial
Conclusions: Treatment of rapid turnover Graves’ disease patients with high dose I-131 (7.4 MBq/g) provides significantly higher cure rates at 12 months, and 3 times odds of cure than 3.7 MBq/g I-131 plus LiCO3 with lesser side effects. We thus recommend 7.4 MBq I-131/g for treatment in these patients. (Source: Medicine)
Source: Medicine - May 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

The Effect of a Tropical Climate on Available Nutrient Resources to Springs in Ophiolite-Hosted, Deep Biosphere Ecosystems in the Philippines
Conclusion Our results allow us to broadly characterize the effect of climate and fluid flow on the carbon and nutrient sources of several serpentinization-driven ecosystems in the Zambales a (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - April 30, 2019 Category: Microbiology Source Type: research

Systems Biology Understanding of the Effects of Lithium on Cancer
Conclusions sections. Both authors shared in the final refinement of the manuscript. Funding Salary support for WG by National Science Foundation grant 1624615 is gratefully acknowledged. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments We gratefully acknowledge very useful comments from Peter Klein on an earlier version of this manuscript, and from the reviewers of this paper, whose comments have resulted in improvements. An earlier version of this...
Source: Frontiers in Oncology - April 29, 2019 Category: Cancer & Oncology Source Type: research

Vitamin B12 Enhances Nerve Repair and Improves Functional Recovery After Traumatic Brain Injury by Inhibiting ER Stress-Induced Neuron Injury
This study also demonstrated that the vitamin B12 could maintain the stability of the microtubule after TBI. As shown in Figure 4, vitamin B12 exerted microtubule-stabilizing effect in vitro and in vivo. Meanwhile, the high dose (1.5 mg/kg) of vitamin B12 treatment showed better effectiveness than the 0.5 mg/kg dose in TBI mice. In addition, the combination therapy with the ER stress inhibitor 4-PBA partially strengthened the neuro-protective effect of vitamin B12. However, whether vitamin B12 directly inhibits the ER stress signaling pathway requires further investigation. CNS injury-induced growth cone collapse and retr...
Source: Frontiers in Pharmacology - April 23, 2019 Category: Drugs & Pharmacology Source Type: research