“Artificial intelligence & COVID-19: (bio)ethical aspects of end of life
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - November 7, 2020 Category: General Medicine Source Type: research

Sleep and immunity in times of COVID-19
CONCLUSION Sleep exercises a direct influence on immunity maintenance and immunological response. Circadian rhythm alterations, associated with the psychological problems imposed by the COVID-19 pandemic compromise the quality of sleep and, for that reason, the immune system.RESUMO OBJETIVOS Analisar como a pandemia de COVID-19 (Sars-CoV-2) e as medidas de restri ção social afetam a qualidade do sono e o sistema imunológico. MÉTODOS Fez-se uma revisão bibliográfica integrativa usando-se artigos científicos dos últimos cinco anos, das bases de dados PubMed, com os desc...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Kawasaki and COVID-19 disease in children: a systematic review
CONCLUSION A significant increase in the incidence of Kawasaki-type diseases after the onset of the epidemic has been reported, suggesting an association between the COVID-19 epidemic and the high incidence of a severe form of KD. However, further studies are needed to conduct an investigation of the association between these two diseases.RESUMO OBJETIVO Apresentar evid ências científicas com base em revisão sistemática da literatura (Prisma) avaliando a associação da Doença de Kawasaki (DK) e COVID-19 em crianças. MÉTODOS Para a seleção dos estudo...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Current evidence of SARS-CoV-2 vertical transmission: an integrative review
CONCLUSION Further studies with a great number of cases are warranted to elucidate whether the virus may be vertically transmitted to the fetus and if any maternal conditions can influence that. Our findings seem to demonstrate that vertical transmission is possible but quite unusual.RESUMO OBJETIVO Revisar as evid ências científicas atuais sobre a transmissão vertical relacionada à infecção pelo novo coronavírus 2019 (COVID-19). MÉTODOS Uma revisão integrativa foi realizada por dois pesquisadores independentes, com base na literatura disponível nas bases...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Safety alert for hospital environments and health professional: chlorhexidine is ineffective for coronavirus
The objective of this study is to compare the different disinfectants used for disinfection on several surfaces, in a review of worldwide works. Scientific studies were researched in the BVS (Virtual Health Library), PubMed, Medline, and ANVISA (National Health Surveillance Agency) databases. The following agents were studied: alcohol 62-71%, hydrogen peroxide 0.5%, sodium hypochlorite 0.1%, benzalkonium chloride 0.05-0.2%, povidone-iodine 10%, and chlorhexidine digluconate 0.02%, on metal, aluminum, wood, paper, glass, plastic, PVC, silicone, latex (gloves), disposable gowns, ceramic, and Teflon surfaces. Studies have sho...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Clinical and socioeconomic characteristics of older adults with COVID-19: A protocol for a rapid systematic review
SUMMARY The aim of this rapid systematic review is to analyze the prevalence of clinical, socioeconomic, and demographic characteristics, laboratory and imaging findings, diagnostic tests, and treatment information of older adults with COVID-19. To conduct this systematic review, the Cochrane Handbook recommendations will be followed. Patients aged 60 years or older with a confirmed diagnosis of SARS-CoV-2 infection will be included. A comprehensive literature search will be performed in the following databases: MEDLINE via PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Latin American and Caribbe...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Renal changes and acute kidney injury in covid-19: a systematic review
CONCLUSION Although COVID-19 affects mainly the lungs, it can also impact the kidneys. Increased serum creatinine and BUN, hematuria, proteinuria, and AKI were frequent findings in patients with severe COVID-19 and were related to an increased mortality rate. Further studies focusing on renal changes and their implications for the clinical condition of patients infected with the novel coronavirus are needed.RESUMO OBJETIVO Apresentar uma revis ão sobre as alterações renais nos pacientes com COVID-19. MÉTODOS Foi realizada uma revisão sistemática de literatura para buscar estudos re...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Ethical dilemmas in COVID-19 times: how to decide who lives and who dies?
The objective of this work is to reflect, from the point of view of medical ethics, on the basic principles of the choices made by the health teams, during the COVID-19 pandemic, whose resources are scarce and decisions cause anguish and restlessness. The ethical values for the rationing of health resources in an epidemic must converge to some proposals based on fundamental values such as maximizing the benefits produced by scarce resources, treating people equally, promoting and recommending instrumental values, giving priority to critical situations. Naturally, different judgments will occur in different circumstances, b...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Chest tubes in COVID-19 times: a safe way to protect the team
CONCLUSIONS Health officials are under increasing pressure to control the spread of COVID-19, which is a very virulent disease. Our analysis brought together old rules against contamination along with new tactics for professionals who deal with chest drains in order to minimize the contamination of teams during the Pandemic. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Impact of oral hygiene in patients undergoing mechanical ventilation in the COVID-19 pandemic
SUMMARY COVID-19, caused by SARS-CoV-2, can present respiratory complications that often lead patients to depend on mechanical ventilation (MV) for several days. It is known that Pneumonia Associated with Mechanical Ventilation (PAMV) is frequent in patients who use this equipment for a long time. As a consequence of COVID-19, its prolonged use can lead to a worse prognosis for the patients. For this reason, in addition to the insufficiency of devices for mechanical ventilation to meet the current demand, it is necessary to adopt measures aimed at preventing complications that may aggravate the patient ’ s clinical c...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Investigation of the frequency of COVID-19 in patients treated with intravesical BCG
CONCLUSION Intravesical BCG administration does not decrease the frequency of COVID-19 infection.RESUMO INTRODU ÇÃO Neste estudo retrospectivo, objetivou-se investigar a frequência de COVID-19 em pacientes com e sem aplicação de BCG por tumor de bexiga. MÉTODOS A presença de COVID-19 foi investigada em 167 pacientes com BCG e 167 sem câncer de bexiga. Todos os pacientes compatíveis para infecção por COVID-19. Resumidamente, os pacientes foram incluídos no estudo com RT-PCR positivo para Sars-CoV-2 e/ou TC de tórax positivo para pneumon...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

The effect of abo and rh blood group antigens on admission to intensive care unit and mortality in patients with COVID-19 infection
CONCLUSION The most frequently seen blood type among COVID-19 patients was A +. The Rh + blood group was found in all cases who were admitted to ICU and had a death outcome. The Rh + blood group was found in a significantly high number of patients who were admitted to ICU, while no significant relationship was found between mortality and Rh blood group.RESUMO OBJETIVO O objetivo deste estudo é analisar o significado prognóstico dos antígenos do grupo sanguíneo ABO e Rh, juntamente com vários parâmetros em pacientes acompanhados com o diagnóstico de COVID-19. MÉTODOS Fo...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Demographic characteristics and neurological comorbidity of patients with COVID-19
SUMMARY ABSTRACT The COVID-19 infection that started in the Wuhan Province of the People's Republic of China and has now spread throughout the world is not limited to the respiratory system, but also causes other systemic symptoms through viremia. Recent data show that the central and peripheral nervous system involvement is particularly substantial. Thus, the present study aims to investigate the current neurological comorbidities and symptoms of patients with COVID-19 who were followed up by our clinic physicians.RESUMO RESUMO A infec ção de COVID-19 que começou na província de Wuhan, na Rep&u...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Neutrophil count to albumin ratio as a new predictor of mortality in patients with COVID-19 ınfection
SUMMARY BACKGROUND Coronavirus Disease 2019 is an acute inflammatory respiratory disease. It causes many changes in hemogram parameters. Low albumin levels are associated with mortality risk in hospitalized patients. The aim of the present study is to reveal the place of neutrophil count to albumin ratio in predicting mortality in patients with COVID-19. METHODS 144 patients, 65 females and 79 males, were included in the study. Patients were divided into 2 groups. Group 1 was the non-severe group (n:85), and Group 2 was severe (n:59). Demographic data, neutrophil, lymphocyte and platelet counts, albumin and C-reactive prot...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Impact of antihypertensive agents on clinical course and in-hospital mortality: analysis of 169 hypertensive patients hospitalized for COVID-19
CONCLUSION The type of antihypertensive agent being used had no effect on the clinical course and mortality in hypertensive patients with COVID-19. The use of these agents should be maintained for the treatment of hypertension d uring hospitalization.RESUMO OBJETIVO A doen ça de coronavírus 2019 (COVID-19) é uma ameaça emergente à saúde causada por um novo coronavírus denominado síndrome respiratória aguda grave coronavírus 2 (Sars-COV-2). Estudos anteriores observaram que a hipertensão está associada a um aumento da mortalidade devido ao C...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

The effects of favipiravir on hematological parameters of covıd-19 patients
CONCLUSION We concluded that the pathological effect of treatment with favipiravir on the hematologic system was the suppression in the erythrocyte series, and there were no adverse effects in other hematologic parameters.RESUMO INTRODU ÇÃO Este estudo tem como objetivo avaliar as alterações nos parâmetros hematológicos após o acompanhamento de pacientes que receberam tratamento com favipiravir devido à infecção por Covid-19. MÉTODOS Sessenta e dois casos em tratamento com favipiravir por pelo menos cinco dias devido à infecção...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

The diagnostic process of covıd-19 in the emergency department: laboratory and ımaging methods
CONCLUSION Laboratory is not specific enough in the pre-diagnosis. In addition, this result does not alter with PCR or CT positivity. However, minimal changes observed in laboratory results may be partially guiding in patients in whom both PCR and CT are positive.RESUMO OBJETIVOS A nova doen ça de coronavírus de 2019 coloca um fardo sério para o sistema de saúde. Portanto, a detecção de pacientes especialmente graves em um estágio inicial é extremamente importante em termos de controle do surto e melhoria do prognóstico. Investigamos o papel dos marcadores infl...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Ventilation mask adapted for endoscopy during the COVID-19 pandemic
SUMMARY In the context of the COVID-19 pandemic, endoscopy services must adopt preventive measures to maintain proper functioning due to a high risk of disease contagion. Triage protocols before and after the procedure, personal protective equipment, and environmental contamination control are some of the endoscopy society ’ s recommendations. However, the risk of infection may remain high due to poor control over the source of contamination.Using a combination of standardized supplies and accessories in a hospital, a ventilation mask adapted to be used in endoscopic procedures is proposed to reduce COVID-19 contamin...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

COVID-19 and acute myocarditis: current literature review and diagnostic challenges
CONCLUSION Despite the COVID-19 pandemic worldwide, a limited number of cases has been shared in the current literature. There are a lot of difficulties in the differential diagnosis of acute myocarditis in the context of COVID-19.RESUMO INTRODU ÇÃO Na literatura atual, houve um aumento dos casos apresentados com doença coronavírus de 2019 (COVID-19) induzida por miocardite aguda. Nesta revisão baseada em casos, buscamos descrever as características clínicas, achados de imagem e curso hospitalar de miocardite aguda. Além disso, as limitações em rela&cced...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Allocation of pharmaceutical resources in maternal and child healthcare institutions during the COVID-19 pandemic
SUMMARY Since the outbreak of a cluster of patients with pneumonia of unknown cause in Wuhan, Hubei Province, China, in December 2019, the disease was later officially named coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), quickly spreading globally. Pregnant women and children are particularly vulnerable during disasters and emergencies. Comprehensive and applicable emergency preparedness and response are definitely important methods to prevent and contain the COVID-19 pandemic. The rational allocation of pharmaceutical resources plays an important role in...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Science of consciousness: reflections on the Pandemic by COVID-19
CONCLUSION The role of a regular practice of activities on the levels of physical fitness is fundamental to define the balance of quality of life during a COVID-19.RESUMO INTRODU ÇÃO A pandemia de COVID-19, causada pela infecção por novo coronavírus humano, foi notificada desde dezembro de 2019, na China, mas apenas oficializada em março de 2020 e, desde então, tem impactado nações do mundo inteiro, tanto pela sua agressividade quanto pela sua velocidade de propaga ção. A sociedade enfrenta a pandemia seguindo as recomendações e dete...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

The effects of the COVID-19 pandemic on levels of physical fitness
CONCLUSION The role of a regular practice of activities on the levels of physical fitness is fundamental to define the balance of quality of life during a COVID-19.RESUMO INTRODU ÇÃO A pandemia de COVID-19, causada pela infecção por novo coronavírus humano, foi notificada desde dezembro de 2019, na China, mas apenas oficializada em março de 2020 e, desde então, tem impactado nações do mundo inteiro, tanto pela sua agressividade quanto pela sua velocidade de propaga ção. A sociedade enfrenta a pandemia seguindo as recomendações e dete...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

COVID-19 and health literacy: the yell of a silent epidemic amidst the pandemic
SUMMARY The emergence of a new form of Coronavirus (SARS-CoV-2) exposed weaknesses of health services in several countries, with overcrowding of hospitals, and lack of supplies and professionals in combating the disease, which sometimes contributed to the installation of social, political, and economic chaos. The critical situation experienced made the subject widely publicized so that the current pandemic also deals with an information epidemic. However, the data received and transmitted require prior critical analysis of its content, although not everyone is able to make the necessary judgment before using or sharing inf...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

In times of COVID-19, epidemiology is a unifying science
SUMMARY In the end of December 2019, China reported an outbreak of pneumonia in Wuhan, a city with more than 11 million inhabitants, to the World Health Organization. Days later, a new agent (SARS-CoV-2) was identified; since then, it has spread throughout the planet, resulting in one of the most challenging pandemics in recent history. Faced with this scenario, Epidemiology plays an important role, given that its techniques and methods have contributed to generating knowledge, assisting in decision making in healthcare. This text presents a succinct reflection regarding the importance of epidemiology in light of the curre...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Risk of venous thromboembolism in users of contraception and menopausal hormone therapy during the COVID-19 pandemic
CONCLUSIONS In this scenario, apart from the fundamental orientations of preventive measures, like social isolation and hygiene, it is important that all female health professionals have knowledge of the new rules and adopt safety measures, especially on the prescription of hormonal therapy and contraception.RESUMO OBJETIVOS A pandemia da COVID-19 é um problema de saúde pública emergente e que tem repercussão internacional. As alterações inflamatórias fazem parte da fisiopatologia da COVID-19 e isso pode acarretar um maior risco tromboembólico em mulheres que fazem us...
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

AMB Guidelines: COVID –19
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Immune status could be associated with severity in COVID-19 patients
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Speech therapy practice in hospital settings and COVID-19 pandemic
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

The doctor-patient relationship in the context of the COVID-19 pandemic
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Bioethical aspects of artificial intelligence: COVID-19 & end of life
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Is it safe to delay testosterone replacement therapy in pandemic times?
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Ipse Dixit
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - September 21, 2020 Category: General Medicine Source Type: research

Drug-induced nephrotoxicity
SUMMARY Acute kidney injury is a very common diagnosis, present in up to 60% of critical patients, and its third main cause is drug toxicity. Nephrotoxicity can be defined as any renal injury caused directly or indirectly by medications, with acute renal failure, tubulopathies, and glomerulopathies as common clinical presentations. Some examples of drugs commonly associated with the acute reduction of glomerular filtration rate are anti-inflammatories, antibiotics, such as vancomycin and aminoglycosides, and chemotherapeutic agents, such as cisplatin and methotrexate. Cases of tubulopathy are very common with amphotericin ...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

HIV-related nephropathy: new aspects of an old paradigm
SUMMARY The scenario of infection by the human immunodeficiency virus (HIV) has been undergoing changes in recent years, both in relation to the understanding of HIV infection and regarding the treatments available. As a result, the disease, which before was associated with high morbidity and mortality, is now seen as a chronic disease that can be controlled, regarding both transmission and symptoms. However, even when the virus replication is well controlled, the infected patient remains at high risk of developing renal involvement, either by acute kidney injury not associated with HIV, nephrotoxicity due to antiretrovira...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Acute kidney injury
SUMMARY A healthy diet is an essential requirement to promote and preserve health, even in the presence of diseases, such as chronic kidney disease (CKD). In this review, nutritional therapy for CKD will be addressed considering not only the main nutrients such as protein, phosphorus, potassium, and sodium, which require adjustments as a result of changes that accompany the reduction of renal functions, but also the benefits of adopting dietary patterns associated with better outcomes for both preventing and treating CKD. We will also emphasize that these aspects should also be combined with a process of giving new meaning...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Diet in Chronic Kidney Disease: an integrated approach to nutritional therapy
SUMMARY A healthy diet is an essential requirement to promote and preserve health, even in the presence of diseases, such as chronic kidney disease (CKD). In this review, nutritional therapy for CKD will be addressed considering not only the main nutrients such as protein, phosphorus, potassium, and sodium, which require adjustments as a result of changes that accompany the reduction of renal functions, but also the benefits of adopting dietary patterns associated with better outcomes for both preventing and treating CKD. We will also emphasize that these aspects should also be combined with a process of giving new meaning...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Anemia in chronic kidney disease
CONCLUSIONS: Cellular therapy with MSCs is very promising and should be part of the treatment of AKI patients in combination with other approaches already available, helping to accelerate recovery and/or slow the progression to chronic kidney disease. Randomized, multicentre controlled studies are needed to develop robust protocols that validate population-based cell therapy with MSCs. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Mesenchymal stem cell therapy in acute kidney injury (AKI): review and perspectives
CONCLUSIONS: Cellular therapy with MSCs is very promising and should be part of the treatment of AKI patients in combination with other approaches already available, helping to accelerate recovery and/or slow the progression to chronic kidney disease. Randomized, multicentre controlled studies are needed to develop robust protocols that validate population-based cell therapy with MSCs. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Peritoneal Dialysis
SUMMARY Peritoneal dialysis (PD) is a renal replacement therapy based on infusing a sterile solution into the peritoneal cavity through a catheter and provides for the removal of solutes and water using the peritoneal membrane as the exchange surface. This solution, which is in close contact with the capillaries in the peritoneum, allows diffusion solute transport and osmotic ultrafiltration water loss since it is hyperosmolar to plasma due to the addition of osmotic agents (most commonly glucose). Infusion and drainage of the solution into the peritoneal cavity can be performed in two ways: manually (continuous ambulatory...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Hyperkalemia in chronic kidney disease
SUMMARY Hyperkalemia is a frequent finding in patients with chronic kidney disease (CKD). This increase in serum potassium levels is associated with decreased renal ion excretion, as well as the use of medications to reduce the progression of CKD or to control associated diseases such as diabetes mellitus and heart failure. Hyperkalemia increases the risk of cardiac arrhythmia episodes and sudden death. Thus, the control of potassium elevation is essential for reducing the mortality rate in this population. Initially, the management of hyperkalemia includes orientation of low potassium diets and monitoring of patients' adh...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Acute kidney injury in cancer patients
SUMMARY The increasing prevalence of neoplasias is associated with new clinical challenges, one of which is acute kidney injury (AKI). In addition to possibly constituting a clinical emergency, kidney failure significantly interferes with the choice and continuation of antineoplastic therapy, with prognostic implications in cancer patients. Some types of neoplasia are more susceptible to AKI, such as multiple myeloma and renal carcinoma. In cancer patients, AKI can be divided into pre-renal, renal (intrinsic), and post-renal. Conventional platinum-based chemotherapy and new targeted therapy agents against cancer are exampl...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

SGLT-2 inhibitors in diabetes: a focus on renoprotection
SUMMARY Type 2 diabetes mellitus is an important public health problem, with a significant impact on cardiovascular morbidity and mortality and an important risk factor for chronic kidney disease. Various hypoglycemic therapies have proved to be beneficial to clinical outcomes, while others have failed to provide an improvement in cardiovascular and renal failure, only reducing blood glucose levels. Recently, sodium-glucose cotransporter-2 (SGLT2) inhibitors, represented by the empagliflozin, dapagliflozin, and canagliflozin, have been showing satisfactory and strong results in several clinical trials, especially regarding...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Fabry disease: genetics, pathology, and treatment
SUMMARY Fabry disease (FD) is a recessive monogenic inheritance disease linked to chromosome X, secondary to mutations in the GLA gene. Its prevalence is estimated between 1:8,454 and 1:117,000 among males and is probably underdiagnosed. Mutations in the GLA gene lead to the progressive accumulation of globotriaosylceramide (Gb3). Gb3 accumulates in lysosomes of different types of cells of the heart, kidneys, skin, eyes, central nervous system, and gastrointestinal system, and may lead to different clinical scenarios. The onset of symptoms occurs during childhood, with acroparesthesia, heat intolerance, and gastrointestina...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Chronic Kidney Disease
The objectives of the conservative treatment for chronic kidney disease are to slow down the progression of kidney dysfunction, treat complications (anemia, bone diseases, cardiovascular diseases), vaccination for hepatitis B, and preparation for kidney replacement therapy. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Novel treatment options for chronic kidney disease complications
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Parkinson's disease and wearable devices, new perspectives for a public health issue: an integrative literature review
SUMMARY Parkinson's disease is the second most common neurodegenerative disease, with an estimated prevalence of 41/100,000 individuals affected aged between 40 and 49 years old and 1,900/100,000 aged 80 and over. Based on the essentiality of ascertaining which wearable devices have clinical literary evidence and with the purpose of analyzing the information revealed by such technologies, we conducted this scientific article of integrative review. It is an integrative review, whose main objective is to carry out a summary of the state of the art of wearable devices used in patients with Parkinson's disease. After the revie...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Therapy for patients with burns - an integrating review
CONCLUSION: the casuistry was low; however, the good results obtained with porous cellulose membrane and silver nanocrystalline dressing are highlighted, since they were used in a larger number of patients in the studies evaluated.RESUMO OBJETIVO: Identificar, por meio de revis ão integrativa, estudos nacionais publicados nos últimos dez anos que destaquem produtos e terapêuticas utilizados nas queimaduras. MÉTODOS: Pesquisa integrativa com estudos publicados nos últimos dez anos. Incluídos os estudos clínicos que descreveram a utilização de terapias já c...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Comment: “Prevalence of falls in elderly people: a population based study”
CONCLUSIONS: We found that approximately one in three elderly individuals fell in the last year.RESUMO INTRODU ÇÃO: A ocorrência de quedas está relacionada a uma interação complexa de fatores de risco, agravados com o envelhecimento. Esta pesquisa teve como objetivo investigar a ocorrência de quedas em idosos, bem como identificar os fatores de risco a esse evento. METODOLOGIA: Estudo transversal, de base populacional, conduzido em município do extremo sul do Brasil. Utilizou-se amostragem probabilística, sendo a unidade amostral os setores censitários. A ...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Prevalence of falls in elderly people: a population based study
CONCLUSIONS: We found that approximately one in three elderly individuals fell in the last year.RESUMO INTRODU ÇÃO: A ocorrência de quedas está relacionada a uma interação complexa de fatores de risco, agravados com o envelhecimento. Esta pesquisa teve como objetivo investigar a ocorrência de quedas em idosos, bem como identificar os fatores de risco a esse evento. METODOLOGIA: Estudo transversal, de base populacional, conduzido em município do extremo sul do Brasil. Utilizou-se amostragem probabilística, sendo a unidade amostral os setores censitários. A ...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Chagas disease is associated with a poor outcome at 1-year follow-up after cardiac resynchronization therapy
CONCLUSION: In a population of HF patients undergoing CRT, CD was independently associated with mortality and hospitalization for HF.RESUMO INTRODU ÇÃO: A terapia de ressincronização cardíaca (TRC) é uma modalidade terapêutica para pacientes com insuficiência cardíaca (IC). A eficácia desse tratamento para redução de eventos baseia-se em ensaios clínicos em que a população de pacientes com doença de Chagas (DC) é sub-representa da. OBJETIVO: Avaliar o prognóstico após TRC em uma populaç&...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research