Drug-induced nephrotoxicity
SUMMARY Acute kidney injury is a very common diagnosis, present in up to 60% of critical patients, and its third main cause is drug toxicity. Nephrotoxicity can be defined as any renal injury caused directly or indirectly by medications, with acute renal failure, tubulopathies, and glomerulopathies as common clinical presentations. Some examples of drugs commonly associated with the acute reduction of glomerular filtration rate are anti-inflammatories, antibiotics, such as vancomycin and aminoglycosides, and chemotherapeutic agents, such as cisplatin and methotrexate. Cases of tubulopathy are very common with amphotericin ...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

HIV-related nephropathy: new aspects of an old paradigm
SUMMARY The scenario of infection by the human immunodeficiency virus (HIV) has been undergoing changes in recent years, both in relation to the understanding of HIV infection and regarding the treatments available. As a result, the disease, which before was associated with high morbidity and mortality, is now seen as a chronic disease that can be controlled, regarding both transmission and symptoms. However, even when the virus replication is well controlled, the infected patient remains at high risk of developing renal involvement, either by acute kidney injury not associated with HIV, nephrotoxicity due to antiretrovira...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Acute kidney injury
SUMMARY A healthy diet is an essential requirement to promote and preserve health, even in the presence of diseases, such as chronic kidney disease (CKD). In this review, nutritional therapy for CKD will be addressed considering not only the main nutrients such as protein, phosphorus, potassium, and sodium, which require adjustments as a result of changes that accompany the reduction of renal functions, but also the benefits of adopting dietary patterns associated with better outcomes for both preventing and treating CKD. We will also emphasize that these aspects should also be combined with a process of giving new meaning...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Diet in Chronic Kidney Disease: an integrated approach to nutritional therapy
SUMMARY A healthy diet is an essential requirement to promote and preserve health, even in the presence of diseases, such as chronic kidney disease (CKD). In this review, nutritional therapy for CKD will be addressed considering not only the main nutrients such as protein, phosphorus, potassium, and sodium, which require adjustments as a result of changes that accompany the reduction of renal functions, but also the benefits of adopting dietary patterns associated with better outcomes for both preventing and treating CKD. We will also emphasize that these aspects should also be combined with a process of giving new meaning...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Anemia in chronic kidney disease
CONCLUSIONS: Cellular therapy with MSCs is very promising and should be part of the treatment of AKI patients in combination with other approaches already available, helping to accelerate recovery and/or slow the progression to chronic kidney disease. Randomized, multicentre controlled studies are needed to develop robust protocols that validate population-based cell therapy with MSCs. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Mesenchymal stem cell therapy in acute kidney injury (AKI): review and perspectives
CONCLUSIONS: Cellular therapy with MSCs is very promising and should be part of the treatment of AKI patients in combination with other approaches already available, helping to accelerate recovery and/or slow the progression to chronic kidney disease. Randomized, multicentre controlled studies are needed to develop robust protocols that validate population-based cell therapy with MSCs. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Peritoneal Dialysis
SUMMARY Peritoneal dialysis (PD) is a renal replacement therapy based on infusing a sterile solution into the peritoneal cavity through a catheter and provides for the removal of solutes and water using the peritoneal membrane as the exchange surface. This solution, which is in close contact with the capillaries in the peritoneum, allows diffusion solute transport and osmotic ultrafiltration water loss since it is hyperosmolar to plasma due to the addition of osmotic agents (most commonly glucose). Infusion and drainage of the solution into the peritoneal cavity can be performed in two ways: manually (continuous ambulatory...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Hyperkalemia in chronic kidney disease
SUMMARY Hyperkalemia is a frequent finding in patients with chronic kidney disease (CKD). This increase in serum potassium levels is associated with decreased renal ion excretion, as well as the use of medications to reduce the progression of CKD or to control associated diseases such as diabetes mellitus and heart failure. Hyperkalemia increases the risk of cardiac arrhythmia episodes and sudden death. Thus, the control of potassium elevation is essential for reducing the mortality rate in this population. Initially, the management of hyperkalemia includes orientation of low potassium diets and monitoring of patients' adh...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Acute kidney injury in cancer patients
SUMMARY The increasing prevalence of neoplasias is associated with new clinical challenges, one of which is acute kidney injury (AKI). In addition to possibly constituting a clinical emergency, kidney failure significantly interferes with the choice and continuation of antineoplastic therapy, with prognostic implications in cancer patients. Some types of neoplasia are more susceptible to AKI, such as multiple myeloma and renal carcinoma. In cancer patients, AKI can be divided into pre-renal, renal (intrinsic), and post-renal. Conventional platinum-based chemotherapy and new targeted therapy agents against cancer are exampl...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

SGLT-2 inhibitors in diabetes: a focus on renoprotection
SUMMARY Type 2 diabetes mellitus is an important public health problem, with a significant impact on cardiovascular morbidity and mortality and an important risk factor for chronic kidney disease. Various hypoglycemic therapies have proved to be beneficial to clinical outcomes, while others have failed to provide an improvement in cardiovascular and renal failure, only reducing blood glucose levels. Recently, sodium-glucose cotransporter-2 (SGLT2) inhibitors, represented by the empagliflozin, dapagliflozin, and canagliflozin, have been showing satisfactory and strong results in several clinical trials, especially regarding...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Fabry disease: genetics, pathology, and treatment
SUMMARY Fabry disease (FD) is a recessive monogenic inheritance disease linked to chromosome X, secondary to mutations in the GLA gene. Its prevalence is estimated between 1:8,454 and 1:117,000 among males and is probably underdiagnosed. Mutations in the GLA gene lead to the progressive accumulation of globotriaosylceramide (Gb3). Gb3 accumulates in lysosomes of different types of cells of the heart, kidneys, skin, eyes, central nervous system, and gastrointestinal system, and may lead to different clinical scenarios. The onset of symptoms occurs during childhood, with acroparesthesia, heat intolerance, and gastrointestina...
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Chronic Kidney Disease
The objectives of the conservative treatment for chronic kidney disease are to slow down the progression of kidney dysfunction, treat complications (anemia, bone diseases, cardiovascular diseases), vaccination for hepatitis B, and preparation for kidney replacement therapy. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Novel treatment options for chronic kidney disease complications
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - January 13, 2020 Category: General Medicine Source Type: research

Parkinson's disease and wearable devices, new perspectives for a public health issue: an integrative literature review
SUMMARY Parkinson's disease is the second most common neurodegenerative disease, with an estimated prevalence of 41/100,000 individuals affected aged between 40 and 49 years old and 1,900/100,000 aged 80 and over. Based on the essentiality of ascertaining which wearable devices have clinical literary evidence and with the purpose of analyzing the information revealed by such technologies, we conducted this scientific article of integrative review. It is an integrative review, whose main objective is to carry out a summary of the state of the art of wearable devices used in patients with Parkinson's disease. After the revie...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Therapy for patients with burns - an integrating review
CONCLUSION: the casuistry was low; however, the good results obtained with porous cellulose membrane and silver nanocrystalline dressing are highlighted, since they were used in a larger number of patients in the studies evaluated.RESUMO OBJETIVO: Identificar, por meio de revis ão integrativa, estudos nacionais publicados nos últimos dez anos que destaquem produtos e terapêuticas utilizados nas queimaduras. MÉTODOS: Pesquisa integrativa com estudos publicados nos últimos dez anos. Incluídos os estudos clínicos que descreveram a utilização de terapias já c...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Comment: “Prevalence of falls in elderly people: a population based study”
CONCLUSIONS: We found that approximately one in three elderly individuals fell in the last year.RESUMO INTRODU ÇÃO: A ocorrência de quedas está relacionada a uma interação complexa de fatores de risco, agravados com o envelhecimento. Esta pesquisa teve como objetivo investigar a ocorrência de quedas em idosos, bem como identificar os fatores de risco a esse evento. METODOLOGIA: Estudo transversal, de base populacional, conduzido em município do extremo sul do Brasil. Utilizou-se amostragem probabilística, sendo a unidade amostral os setores censitários. A ...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Prevalence of falls in elderly people: a population based study
CONCLUSIONS: We found that approximately one in three elderly individuals fell in the last year.RESUMO INTRODU ÇÃO: A ocorrência de quedas está relacionada a uma interação complexa de fatores de risco, agravados com o envelhecimento. Esta pesquisa teve como objetivo investigar a ocorrência de quedas em idosos, bem como identificar os fatores de risco a esse evento. METODOLOGIA: Estudo transversal, de base populacional, conduzido em município do extremo sul do Brasil. Utilizou-se amostragem probabilística, sendo a unidade amostral os setores censitários. A ...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Chagas disease is associated with a poor outcome at 1-year follow-up after cardiac resynchronization therapy
CONCLUSION: In a population of HF patients undergoing CRT, CD was independently associated with mortality and hospitalization for HF.RESUMO INTRODU ÇÃO: A terapia de ressincronização cardíaca (TRC) é uma modalidade terapêutica para pacientes com insuficiência cardíaca (IC). A eficácia desse tratamento para redução de eventos baseia-se em ensaios clínicos em que a população de pacientes com doença de Chagas (DC) é sub-representa da. OBJETIVO: Avaliar o prognóstico após TRC em uma populaç&...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Predictive value of ATRIA risk score for contrast-induced nephropathy after percutaneous coronary intervention for ST-segment elevation myocardial infarction
SUMMARY BACKGROUND: The AnTicoagulation and Risk factors In Atrial fibrillation (ATRIA) risk score used to detect the thromboembolic and hemorrhagic risk in atrial fibrillation patients has been shown recently to predict poor clinical outcomes in patients with acute myocardial infarction (ACS), regardless of having atrial fibrillation (AF). We aimed to analyze the relationship between different risk scores and contrast-induced nephropathy (CIN) development in patients with ACS who underwent urgent percutaneous coronary intervention (PCI) and compare the predictive ability of the ATRIA risk score with the MEHRAN risk score....
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Seasonal variation of clinical characteristics and prognostic of adult patients admitted to an intensive care unit
CONCLUSION: It was possible to observe variations of the clinical characteristics and prognosis of patients; summer months presented a higher proportion of clinical and emergency surgery patients, with higher mortality rates. Sepsis at ICU admission did not show seasonal behavior. A seasonal pattern was found for mortality rate.RESUMO OBJETIVO: Analisar varia ções sazonais dos padrões clínicos, uso de recursos terapêuticos e resultados da internação de pacientes adultos admitidos na unidade de terapia intensiva. MÉTODOS: Estudo de coorte retrospectivo realizado de jane...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Cardiac and extra-cardiac pathologies in patients with acute arterial occlusion
CONCLUSION: Cardiac and extra-cardiac pathologies should be kept in mind in patients with acute arterial occlusion. Thus, detected pathologies could be treated, and the development of additional peripheral emboli could be prevented.RESUMO OBJETIVO: O objetivo do estudo é investigar patologias cardíacas e extracardíacas em pacientes operados por oclusão arterial aguda. MÉTODOS: Entre março de 2010 e março de 2018, um total de 120 pacientes submetidos a tratamento cirúrgico para oclusão arterial aguda foram incluídos neste estudo retrospectivo. RESULTADO S...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Burnout Syndrome in medical internship students and its prevention with Balint Group
CONCLUSIONS: The prevalence of two-dimensional Burnout Syndrome was high, with factors associated with the educational process. Participation in BG was associated with a lower Burnout rate prevalence. Longitudinal studies should be c onducted.RESUMO OBJETIVO: Estimar a preval ência de Síndrome de Burnout (SB) e fatores associados entre os internos de medicina de uma universidade pública no Nordeste do Brasil, além de investigar a contribuição do Grupo Balint (GB) na sua prevenção. MÉTODOS: Estudo transversal em fevereiro/2018 com os internos de medicina da univ ...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Comment: “Burnout syndrome should not be underestimated”
SUMMARY OBJECTIVES: Burnout syndrome can be seen among health professionals at every stage of their careers. The incidence of burnout syndrome among health care professionals has increased in recent years and varies between countries and depending on different areas of specialization and work units. It is known that burnout syndrome significantly affects the work and social life of individuals. We aimed to investigate the effect of burnout syndrome on trauma and infection. METHODS: The study was conducted in the Alanya Alaaddin Keykubat University, Faculty of Medicine, Training and Research Hospital. All health professiona...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Burnout syndrome should not be underestimated
SUMMARY OBJECTIVES: Burnout syndrome can be seen among health professionals at every stage of their careers. The incidence of burnout syndrome among health care professionals has increased in recent years and varies between countries and depending on different areas of specialization and work units. It is known that burnout syndrome significantly affects the work and social life of individuals. We aimed to investigate the effect of burnout syndrome on trauma and infection. METHODS: The study was conducted in the Alanya Alaaddin Keykubat University, Faculty of Medicine, Training and Research Hospital. All health professiona...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Electronic prescription: frequency and severity of medication errors
SUMMARY OBJECTIVE: To assess the frequency and severity of prescriptions errors with potentially dangerous drugs (heparin and potassium chloride for injection concentrate) before and after the introduction of a computerized provider order entry (CPOE) system. METHODS: This is a retrospective study that compared errors in manual/pre-typed prescriptions in 2007 (Stage 1) with CPOE prescriptions in 2014 (Stage 2) (Total = 1,028 prescriptions), in two high-complexity hospitals of Belo Horizonte, Brasil. RESULTS: An increase of 25% in the frequency of errors in Hospital 1 was observed after the intervention (p
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Bronchodilator test in extreme old age: Adverse effects of short-acting beta-2 adrenergic agonists with clinical repercussion and bronchodilator response
CONCLUSIONS: Chronological age is not a limiting factor for the bronchodilator t est, short-acting beta-2 agonists did not present adverse effects with significant clinical repercussion and were useful in the diagnosis and therapeutic guidance of extreme-old-age patients.RESUMO OBJETIVOS: Avaliar se idade cronol ógica é um fator limitante para realizar prova broncodilatadora, determinar efeitos adversos significativos com repercussão clínica dos beta-2 agonistas de curta ação e avaliar a resposta broncodilatadora na espirometria, na velhice extrema. MÉTODOS: Estudo transvers...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

The effects of physical activity during childhood, adolescence, and adulthood on cardiovascular risk factors among adults
SUMMARY OBJECTIVES: To analyze the association between physical activity during life and cardiovascular risk factors among adults. DESIGN: The sample was composed of 101 adults (59 men) between 30 and 50 years old, who were recruited from different gyms and from a University in Brasil. Participants were divided according to their engagement in sports in early life (self-reported) and current physical activity (pedometer) (sports participation during childhood/adolescence and currently active [n=26], sports participation during childhood/adolescence and currently inactive [n=26], and control [n=49]). Cardiovascular risk fac...
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Urinary lithiasis: diagnostic investigation
The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standardize producers to assist the reasoning and decision-making of doctors. The information provided through this project must be assessed and criticized by the physician responsible for the conduct that will be adopted, depending on the conditions and the clinical status of each patient. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Urinary lithiasis: evaluation of the use of laser vs. Pneumatic ureteral lithotripsy
The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standardize producers to assist the reasoning and decision-making of doctors. The information provided through this project must be assessed and criticized by the physician responsible for the conduct that will be adopted, depending on the conditions and the clinical status of each patient. (Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Right ventricular function in dilated cardiomyopathies with chagasic and idiopathic etiologies
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - December 3, 2019 Category: General Medicine Source Type: research

Viability of mobile applications for remote support of radiotherapy patients
CONCLUSIONS We did not find an expressive number of works on this subject in Brasil. Mobile applications have the potential to assist in the remote support of radiotherapy patients. The latest studies suggest the need for a regulation of data protection protocols to be deployed.RESUMO INTRODU ÇÃO O avanço tecnológico no século XXI tem proporcionado maior comunicação entre todos, independentemente da classe socioeconômica e da faixa etária. Ações de fomento ao desenvolvimento de aplicativos para a área da saúde estão surgindo ao...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Raynaud’s phenomenon in the occupational context
SUMMARY OBJECTIVE To review articles that evaluated the prevalence of Raynaud ’ s phenomenon of occupational origin. METHODS The search for articles was carried out in the Medline (via PubMed), Embase, Web of Science, Scientific Electronic Library Online (SciELO), and Latin America and Caribbean Health Sciences Literature (Lilacs) databases. RESULTS 64 articles were obtained from the electronic search; 18 articles met the eligibility criteria. All studies discussed the exposure to vibrations in the upper limbs. In 6 of them, the thermal issue was directly or indirectly addressed. No studies have addressed exposure to...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Fever of unknown origin in special groups
SUMMARY Fever of undetermined origin (FUO) is a challenging entity with a striking presence in hospitals around the world. It is defined as temperature ≥ 37.8 ° C on several occasions, lasting ≥ three weeks, in the absence of diagnosis after three days of hospital investigation or 3 outpatient visits. The main etiologies are infectious, neoplastic, and non-infectious inflammatory diseases. The diagnosis is based on the detailed clinical history and physical examination of these patients, in order to direct the specific complementary tests to be performed in each case. The initial diagnostic approach of the FUO pa...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Basic Life Support: an accessible tool in layperson training
SUMMARY OBJECTIVES 1) To evaluate the efficiency of a new method of training laypeople on cardiopulmonary resuscitation (CPR). 2) To assess previous knowledge of the participants. METHODS Instructors were trained according to the 2015 American Heart Association Guidelines, with emphasis on CPR. Dummies made with PET bottles were used, and a questionnaire was applied to the participants before and after training. Statistical analysis was performed in the R commander program. Participants with incomplete documents were excluded from the study. RESULTS Out of 101 participants, 96 were included: 69 lay people, 17 health profes...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

HIF-1α Levels in patients receiving chemoradiotherapy for locally advanced non-small cell lung carcinoma
SUMMARY AIM To examine the relationship between treatment response and hypoxia-inducible factor-1 alpha (HIF-1 α ) levels in patients with locally advanced non-small cell lung cancer (NSCLC) who received chemoradiotherapy (CRT). METHODS Eighty patients with NSCLC were included in the study and treated at Acibadem Mehmet Ali Ayd ı nlar University Medical Faculty. HIF-1 α levels were measured before and after CRT by the enzyme-linked immunosorbent assay (ELISA) method. RESULTS Patients ’ stages were as follows; stage IIIA (65%) and stage IIIB (35%). Squamous histology was 45%, adenocarcinoma was 44%, and o...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Edition of Portuguese health journals and its relationship with their visibility: a quantitative analysis
CONCLUSION Despite the high rate of compliance with editorial quality criteria, the international visibility of the journals analyzed is still scarce. This reveals the need for the development of complementary competences.RESUMO OBJETIVO No âmbito das ciências da saúde, as revistas científicas desempenham um papel fulcral, contribuindo — para al ém da divulgação dos resultados científicos — para o progresso da medicina e para a forma ção dos investigadores. A visibilidade da produção científica é fundamental para o d...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

The usefulness of Tanita TBF-310 for body composition assessment in Judo athletes using a four-compartment molecular model as the reference method
In conclusion, TBF-310 Tanita is not a valid alternative method for estimating body composition in highly trained judo athletes.RESUMO A avalia ção da composição corporal ao nível molecular é relevante para a população esportiva e sua associação com o alto rendimento é bem reconhecida. O modelo molecular a quatro compartimentos (4C) é o método de referência para as estimativas de massa gorda (MG) e massa livre de gordura (MLG) . No entanto, sua implementação no contexto real não é viável. T&ea...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Gynecological cancer and metabolic screening of 1001 elderly Brazilian women
CONCLUSIONS our data suggest that a great reduction in BMI and stature is more frequent in the group over 75 years. Also, systemic arterial hypertension and carbohydrate disturbance are frequent morbidities in women over 65 years.RESUMO OBJETIVO O objetivo deste trabalho foi estudar retrospectivamente alguns dados cl ínicos, laboratoriais e imagens de um grupo de idosas brasileiras. MÉTODOS Estudo observacional retrospectivo realizado com inclusão de 1.001 mulheres brasileiras atendidas no ambulatório de geriatria ginecológica de nossa instituição. Foram analisados: a idade ...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Multidisciplinary protocol for the management of fibromyalgia associated with imbalance. Our experience and literature review
We reported our multidisciplinary protocol for the management of fibromyalgia associated with imbalance. Our aim was to verify the effectiveness of a proprioceptive training program as a complementary therapy for a traditional protocol of education, mindfulness, and exercise training for the management of fibromyalgia associated with imbalance. METHODS Retrospective cohort study on 84 women, with primary fibromyalgia associated to imbalance. A group of patients performed traditional exercise training; in a second group the training was supplemented with proprioception exercises. Each session lasted from 40 to 60 minutes an...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Basal insulin persistence in Brazilian participants with T2DM
CONCLUSION The benefits of basal insulin therapy motivated continuers to persist with the treatment; experienced or anticipated side effects contributed to interruption and discontinuation. Physician and patient training is key in the treatment of diabetes.RESUMO OBJETIVO Dados de vida real sobre como a efic ácia da terapia com insulina é afetada pela baixa persistência ao tratamento que ocorre logo após o início da terapia. Esta análise é a parte brasileira de um estudo transversal internacional conduzido em pacientes com DM2 que teve como objetivo descrever as razões...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Clinical aspects of congenital microcephaly syndrome by Zika virus in a rehabilitation center for patients with microcephaly
CONCLUSION Epilepsy, irritability, dysphagia, and musculoskeletal comorbidities were the most frequent clinical variables in children with microcephaly. There was a high prevalence of congenital ZIKV microcephaly syndrome in this sample.RESUMO OBJETIVO Pretende-se, neste estudo, identificar a preval ência de variáveis clínicas em crianças com microcefalia. MÉTODOS Trata-se de um estudo transversal e observacional com dados coletados de prontuários de pacientes admitidos no ambulatório de microcefalia de um centro de referência em Teresina (PI). Foram coletados dados dem...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Current status of Brazilian interprofessional education: a national survey comparing physical therapy and medical schools
CONCLUSION These results will help in the development of future interventions that can enhance IPE in curricula in developing countries.RESUMO OBJETIVOS Investigar quantas escolas m édicas e de fisioterapia brasileiras possuem iniciativas e cursos relacionados à EIP nos currículos, avaliando as barreiras e fatores associados com essa implementação e comparando as diferenças entre esses dois cursos. MÉTODOS Essa pesquisa nacional foi conduzida em 2017 e incluiu represen tantes das escolas médicas e de fisioterapia no Brasil. As ofertas de atividades interprofissionais,...
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Total and partial laparoscopic adrenalectomy
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Peyronie’s disease: clinical treatment
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

From the measles-free status to the current outbreak in Brasil
(Source: Revista da Associacao Medica Brasileira)
Source: Revista da Associacao Medica Brasileira - November 8, 2019 Category: General Medicine Source Type: research

Use of dupilumab on the treatment of moderate-to-severe asthma: a systematic review
CONCLUSIONS Dupilumab is promising for the treatment of asthma, whereas conventional therapy is deemed to be insufficient. More additional studies are needed to confirm the long-term safety and effectiveness.RESUMO OBJETIVO Este artigo teve como objetivo fazer uma revis ão sistemática sobre o tratamento da asma moderada a grave, administrando Dupilumabe. MÉTODOS Foi realizada uma busca nas plataformas on-line Ebsco, SciELO, PubMed, Medline Bireme, Lilacs e New England Journal of Medicine. Foram selecionadas publicações de 2010 a 2018 referentes a artigos que continham grupos controle, que...
Source: Revista da Associacao Medica Brasileira - October 11, 2019 Category: General Medicine Source Type: research

Treatment of iron overload syndrome: a general review
CONCLUSION Advances in the understanding of iron overload have lead to great advances in therapies and new pharmacological targets. Research has lead to better compliance with the use of oral chelators and less toxic drugs.RESUMO INTRODU ÇÃO A síndrome de sobrecarga de ferro engloba um grande espectro de etiologias que levam a um aumento da quantidade de ferro nos tecidos. Esse ferro excede a capacidade de proteção dos tecidos, levando a dano oxidativo e lesão tissular. Tratamento pode prevenir esse dano, levando à melhor so brevida. METODOLOGIA A literatura dos últim...
Source: Revista da Associacao Medica Brasileira - October 11, 2019 Category: General Medicine Source Type: research

Adolescent pregnancy trends in the last decade
CONCLUSION Teenage pregnancy in Brasil is in slow decline, especially among mothers aged 10-14 years and is inversely associated with the HDI, except in the Northeast.RESUMO INTRODU ÇÃO A gravidez na adolescência é fenômeno universal, com maior prevalência nos países em desenvolvimento. Embora venha apresentando redução desde 2000 no Brasil, a taxa de fecundidade específica para essa faixa etária permanece elevada. OBJETIVO Avaliar a frequência da gravidez na ado lescência no Brasil, no período de 2006 a 2015, e a associaç&a...
Source: Revista da Associacao Medica Brasileira - October 11, 2019 Category: General Medicine Source Type: research

Comments: “TEP versus Lichtenstein, Which One to Choose? A Retrospective Cohort Study”
CONCLUSIONS TEP is superior to Lichtenstein with shorter hospitalization duration and lower rates of early postoperative pain. No difference between the two techniques was found for chronic pain. We believe that laparoscopic hernioplasty approach may be the best alternative technique for inguinal hernia repair.RESUMO OBJETIVOS As t écnicas de hernioplastia inguinal foram melhoradas desde a primeira hernioplastia. Técnicas livres de tensão que aplicam materiais de malha sintética, como na abordagem de Lichtenstein, são o padrão ouro. A hernioplastia laparoscópica é a a...
Source: Revista da Associacao Medica Brasileira - October 11, 2019 Category: General Medicine Source Type: research

TEP versus Lichtenstein, which one to choose? A retrospective cohort study
CONCLUSIONS TEP is superior to Lichtenstein with shorter hospitalization duration and lower rates of early postoperative pain. No difference between the two techniques was found for chronic pain. We believe that laparoscopic hernioplasty approach may be the best alternative technique for inguinal hernia repair.RESUMO OBJETIVOS As t écnicas de hernioplastia inguinal foram melhoradas desde a primeira hernioplastia. Técnicas livres de tensão que aplicam materiais de malha sintética, como na abordagem de Lichtenstein, são o padrão ouro. A hernioplastia laparoscópica é a a...
Source: Revista da Associacao Medica Brasileira - October 11, 2019 Category: General Medicine Source Type: research