Global Cancer Inequalities
Miranda M. Fidler, Freddie Bray (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 14, 2018 Category: Cancer & Oncology Source Type: research

Not Only Redox: The Multifaceted Activity of Cerium Oxide Nanoparticles in Cancer Prevention and Therapy
Francesca Corsi, Fanny Caputo, Enrico Traversa, Lina Ghibelli (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 14, 2018 Category: Cancer & Oncology Source Type: research

The Prognostic Role of Circulating Tumor Cells (CTCs) in Lung Cancer
Joanna Kapeleris, Arutha Kulasinghe, Majid E. Warkiani, Ian Vela, Liz Kenny, Kenneth O'Byrne, Chamindie Punyadeera (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 14, 2018 Category: Cancer & Oncology Source Type: research

Computational Structural Biology of S-nitrosylation of Cancer Targets
Emmanuelle Bignon, Maria Francesca Allega, Marta Lucchetta, Matteo Tiberti, Elena Papaleo (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 14, 2018 Category: Cancer & Oncology Source Type: research

Management of the Airway for Transoral Robotic Supraglottic Partial Laryngectomy
Vanessa C. Stubbs, Karthik Rajasekaran, Adam R. Gigliotti, Ahmad F. Mahmoud, Robert M. Brody, Jason G. Newman, Christopher H. Rassekh, Gregory S. Weinstein (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 14, 2018 Category: Cancer & Oncology Source Type: research

Single Stage Transoral Laser Microsurgery for Early Glottic Cancer
Yaniv Hamzany, Hagit Shoffel-Havakuk, Stav Devons-Sberro, Shani Shteinberg, Dan Yaniv, Aviram Mizrachi (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 14, 2018 Category: Cancer & Oncology Source Type: research

T-Cell Leukemia/Lymphoma 1 (TCL1): An Oncogene Regulating Multiple Signaling Pathways
Francesco Paduano, Eugenio Gaudio, Afua A. Mensah, Sandra Pinton, Francesco Bertoni, Francesco Trapasso (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 13, 2018 Category: Cancer & Oncology Source Type: research

Metabolic Switch in the Tumor Microenvironment Determines Immune Responses to Anti-cancer Therapy
Barbara Wegiel, Marta Vuerich, Saeed Daneshmandi, Pankaj Seth (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 13, 2018 Category: Cancer & Oncology Source Type: research

EBV Associated Breast Cancer Whole Methylome Analysis Reveals Viral and Developmental Enriched Pathways
Mohammad O. E. Abdallah, Ubai K. Algizouli, Maram A. Suliman, Rawya A. Abdulrahman, Mahmoud Koko, Ghimja Fessahaye, Jamal H. Shakir, Ahmed H. Fahal, Ahmed M. Elhassan, Muntaser E. Ibrahim, Hiba S. Mohamed (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 13, 2018 Category: Cancer & Oncology Source Type: research

Glioblastoma Recurrence Correlates With Increased APE1 and Polarization Toward an Immuno-Suppressive Microenvironment
Amanda L. Hudson, Nicole R. Parker, Peter Khong, Jonathon F. Parkinson, Trisha Dwight, Rowan J. Ikin, Ying Zhu, Jason Chen, Helen R. Wheeler, Viive M. Howell (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 13, 2018 Category: Cancer & Oncology Source Type: research

Mutation Detection in Tumor-Derived Cell Free DNA Anticipates Progression in a Patient With Metastatic Colorectal Cancer
Bruna D. de Figueiredo Barros, Bruna E. C. Kupper, Samuel Aguiar Junior, Celso A. L. de Mello, Maria D. Begnami, Rubens Chojniak, Sandro J. de Souza, Giovana T. Torrezan, Dirce M. Carraro (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 10, 2018 Category: Cancer & Oncology Source Type: research

Ambivalence: A Key to Clinical Trial Participation?
Janice A. Chilton, Monica L. Rasmus, Jay Lytton, Charles D. Kaplan, Lovell A. Jones, Thelma C. Hurd (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 10, 2018 Category: Cancer & Oncology Source Type: research

Current Landscape of Targeted Therapies for Hormone-Receptor Positive, HER2 Negative Metastatic Breast Cancer
Tarah J. Ballinger, Jason B. Meier, Valerie M. Jansen (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 10, 2018 Category: Cancer & Oncology Source Type: research

Targeting Cyclin-Dependent Kinases for Treatment of Gynecologic Cancers
Z. Ping Lin, Yong-Lian Zhu, Elena S. Ratner (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 8, 2018 Category: Cancer & Oncology Source Type: research

Patterns of Distant Metastasis Between Histological Types in Esophageal Cancer
San-Gang Wu, Wen-Wen Zhang, Jia-Yuan Sun, Feng-Yan Li, Qin Lin, Zhen-Yu He (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 8, 2018 Category: Cancer & Oncology Source Type: research

The Activation and Signaling Mechanisms of GPR56/ADGRG1 in Melanoma Cell
Kuan-Yeh Huang, Hsi-Hsien Lin (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 8, 2018 Category: Cancer & Oncology Source Type: research

BCMA (TNFRSF17) Induces APRIL and BAFF Mediated Breast Cancer Cell Stemness
Vasiliki Pelekanou, George Notas, Paraskevi Athanasouli, Konstantinos Alexakis, Fotini Kiagiadaki, Nikolaos Peroulis, Konstantina Kalyvianaki, Errika Kampouri, Hara Polioudaki, Panayiotis Theodoropoulos, Andreas Tsapis, Elias Castanas, Marilena Kampa (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 7, 2018 Category: Cancer & Oncology Source Type: research

Assessing the Impact of Circulating Tumor DNA (ctDNA) in Patients With Colorectal Cancer: Separating Fact From Fiction
Emmanuel Gabriel, Sanjay P. Bagaria (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 6, 2018 Category: Cancer & Oncology Source Type: research

The Guanylate Cyclase C —cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia
Jeffrey A. Rappaport, Scott A. Waldman (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 6, 2018 Category: Cancer & Oncology Source Type: research

Prostate-Specific Antigen Trends Predict the Probability of Prostate Cancer in a Very Large U.S. Veterans Affairs Cohort
R. Jeffrey Karnes, F. Roy MacKintosh, Christopher H. Morrell, Lori Rawson, Preston C. Sprenkle, Michael W. Kattan, Michele Colicchia, Thomas B. Neville (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 6, 2018 Category: Cancer & Oncology Source Type: research

Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy
Thibault Le Bourgeois, Laura Strauss, Halil-Ibrahim Aksoylar, Saeed Daneshmandi, Pankaj Seth, Nikolaos Patsoukis, Vassiliki A. Boussiotis (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 3, 2018 Category: Cancer & Oncology Source Type: research

Epstein –Barr Virus-Associated Malignancies: Roles of Viral Oncoproteins in Carcinogenesis
Ahmed El-Sharkawy, Lobna Al Zaidan, Ahmed Malki (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 2, 2018 Category: Cancer & Oncology Source Type: research

Smurfs in Protein Homeostasis, Signaling, and Cancer
Praveen Koganti, Gal Levy-Cohen, Michael Blank (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - August 2, 2018 Category: Cancer & Oncology Source Type: research

Editorial: Targeting Phosphorylation and Glycosylation of Membrane-Bound Oncogenic Drivers, Receptors and Adhesion Molecules to Control Constitutive Proliferation of Human Carcinoma Cells
Muhammad R. M. Hussain, Daniel C. Hoessli (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 31, 2018 Category: Cancer & Oncology Source Type: research

“Do We Know Jack” About JAK? A Closer Look at JAK/STAT Signaling Pathway
Emira Bousoik, Hamidreza Montazeri Aliabadi (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 31, 2018 Category: Cancer & Oncology Source Type: research

Nucleotide Excision Repair Factor XPC Ameliorates Prognosis by Increasing the Susceptibility of Human Colorectal Cancer to Chemotherapy and Ionizing Radiation
Liang-Bo Hu, Yin Chen, Xiao-Dong Meng, Pan Yu, Xu He, Jie Li (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 31, 2018 Category: Cancer & Oncology Source Type: research

Evaluation of Radiomics to Predict the Accuracy of Markerless Motion Tracking of Lung Tumors: A Preliminary Study
Kevin Nguyen, Maksat Haytmyradov, Hassan Mostafavi, Rakesh Patel, Murat Surucu, Alec Block, Matthew M. Harkenrider, John C. Roeske (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 31, 2018 Category: Cancer & Oncology Source Type: research

Organ-Specific Toxicities Due to Radiation Therapy in Cancer Patients With or Without HIV Infection: A Systematic Review of the Literature
Melody J. Xu, Alison Liewen, Luca Valle, Adam C. Olson, Nicola M. Zetola, Surbhi Grover (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 30, 2018 Category: Cancer & Oncology Source Type: research

Microenvironment Cell Contribution to Lymphoma Immunity
Deepika Kumar, Mina L. Xu (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 27, 2018 Category: Cancer & Oncology Source Type: research

Diagnosis, Pathological Findings, and Clinical Management of Gangliocytic Paraganglioma: A Systematic Review
Yoichiro Okubo, Emi Yoshioka, Masaki Suzuki, Kota Washimi, Kae Kawachi, Yoichi Kameda, Tomoyuki Yokose (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 27, 2018 Category: Cancer & Oncology Source Type: research

Management of Leptomeningeal Metastases in Non-oncogene Addicted Non-small Cell Lung Cancer
Ana Turkaj, Anna M. Morelli, Tiziana Vaval à, Silvia Novello (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 27, 2018 Category: Cancer & Oncology Source Type: research

Transoral Robotic Surgery in the Nordic Countries: Current Status and Perspectives
Antti A. M äkitie, Harri Keski-Säntti, Mari Markkanen-Leppänen, Leif Bäck, Petri Koivunen, Tomas Ekberg, Karl Sandström, Göran Laurell, Mathias von Beckerath, Johan S. Nilsson, Peter Wahlberg, Lennart Greiff, Lena Norberg Spaak, Thomas Kjærgaard, Christian Godballe, Oddveig Rikardsen, Hani Ibrahim Chann ir, Niclas Rubek, Christian von Buchwald (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 27, 2018 Category: Cancer & Oncology Source Type: research

The Role of Machine Learning in Knowledge-Based Response-Adapted Radiotherapy
Huan-Hsin Tseng, Yi Luo, Randall K. Ten Haken, Issam El Naqa (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 27, 2018 Category: Cancer & Oncology Source Type: research

Inhibiting the NLRP3 Inflammasome With Methylene Blue as Treatment Adjunct in Myelodysplasia
Richard E. Kast (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 27, 2018 Category: Cancer & Oncology Source Type: research

The Impact of Serum Glucose, Anti-Diabetic Agents, and Statin Usage in Non-small Cell Lung Cancer Patients Treated With Definitive Chemoradiation
Nick A. Iarrobino, Beant S. Gill, Mark Bernard, Rainer J. Klement, Maria Werner-Wasik, Colin E. Champ (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 27, 2018 Category: Cancer & Oncology Source Type: research

Quantitative Analysis of BRCA1 and BRCA2 Germline Splicing Variants Using a Novel RNA-Massively Parallel Sequencing Assay
Suzette Farber-Katz, Vickie Hsuan, Sitao Wu, Tyler Landrith, Huy Vuong, Dong Xu, Bing Li, Jayne Hoo, Stephanie Lam, Sarah Nashed, Deborah Toppmeyer, Phillip Gray, Ginger Haynes, Hsiao-Mei Lu, Aaron Elliott, Brigette Tippin Davis, Rachid Karam (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 27, 2018 Category: Cancer & Oncology Source Type: research

Prognostic Factors for Elderly Patients Treated With Stereotactic Body Radiation Therapy for Pancreatic Adenocarcinoma
Philip A. Sutera, Mark E. Bernard, Hong Wang, Dwight E. Heron (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 27, 2018 Category: Cancer & Oncology Source Type: research

The Prevention of Brain Metastases in Non-Small Cell Lung Cancer by Prophylactic Cranial Irradiation
Willem J. A. Witlox, Bram L. T. Ramaekers, Jaap D. Zindler, Dani ëlle B. P. Eekers, Judith G. M. van Loon, Lizza E. L. Hendriks, Anne-Marie C. Dingemans, Dirk K. M. De Ruysscher (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 26, 2018 Category: Cancer & Oncology Source Type: research

Rationale for Combining Bispecific T Cell Activating Antibodies With Checkpoint Blockade for Cancer Therapy
Sebastian Kobold, Stanislav Pantelyushin, Felicitas Rataj, Johannes vom Berg (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 25, 2018 Category: Cancer & Oncology Source Type: research

Trastuzumab Emtansine for the Treatment of HER-2 Positive Carcinoma Ex-pleomorphic Adenoma Metastatic to the Brain: A Case Report
Ihab Hassanieh, Lara Hilal, Karine A. Al Feghali, Ibrahim Khalifeh, Bassem Youssef (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 24, 2018 Category: Cancer & Oncology Source Type: research

A Novel DPYD Variant Associated With Severe Toxicity of Fluoropyrimidines: Role of Pre-emptive DPYD Genotype Screening
Chi C. Tong, Ching W. Lam, Ka O. Lam, Victor H. F. Lee, Mai-Yee Luk (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 24, 2018 Category: Cancer & Oncology Source Type: research

Atezolizumab for the First-Line Treatment of Non-small Cell Lung Cancer (NSCLC): Current Status and Future Prospects
Rachel Ryu, Kristina E. Ward (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 24, 2018 Category: Cancer & Oncology Source Type: research

Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?
Venus Sosa Iglesias, Lorena Giuranno, Ludwig J. Dubois, Jan Theys, Marc Vooijs (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 24, 2018 Category: Cancer & Oncology Source Type: research

The Use of Circulating Tumor DNA for Prognosis of Gastrointestinal Cancers
Hariti Saluja, Christos S. Karapetis, Susanne K. Pedersen, Graeme P. Young, Erin L. Symonds (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 24, 2018 Category: Cancer & Oncology Source Type: research

nab-Paclitaxel-Based Therapy in Underserved Patient Populations: The ABOUND.70+ Study in Elderly Patients With Advanced NSCLC
Corey J. Langer, Edward S. Kim, Eric C. Anderson, Robert M. Jotte, Manuel Modiano, Daniel E. Haggstrom, Matei P. Socoteanu, David A. Smith, Christopher Dakhil, Kartik Konduri, Tymara Berry, Teng J. Ong, Alexandra Sanford, Katayoun Amiri, Jonathan W. Goldman, Jared Weiss, on behalf of the ABOUND.70+ Investigators , Ajeet Gajra, Andrei Dobrescu, Bohdan E. Halibey, Corey Langer, Daniel Haggstrom, David A. Smith, Eric Anderson, Eugene H. Paschold, Haiying Cheng, Haythem Ali, Hossein Borghaei, Jared Weiss, Jawad Elias Francis, Ayla Ahmed Kessler, Jen C. Wang, Jonathan Wade Goldman, Jose E. Najera, Nadim F. Nimeh, Joseph Rosales...
Source: Frontiers in Oncology - July 24, 2018 Category: Cancer & Oncology Source Type: research

nab-Paclitaxel –Based Therapy in Underserved Patient Populations: The ABOUND.PS2 Study in Patients With NSCLC and a Performance Status of 2
Ajeet Gajra, Nagla Abdel Karim, Deborah A. Mulford, Liza Cosca Villaruz, Marc Ryan Matrana, Haythem Y. Ali, Edgardo S. Santos, Tymara Berry, Teng Jin Ong, Alexandra Sanford, Katayoun Amiri, David R. Spigel (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 24, 2018 Category: Cancer & Oncology Source Type: research

Patient Selection in Human Papillomavirus Related Oropharyngeal Cancer: The Added Value of Prognostic Models in the New TNM 8th Edition Era
Sarah Deschuymer, R üveyda Dok, Annouschka Laenen, Esther Hauben, Sandra Nuyts (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 23, 2018 Category: Cancer & Oncology Source Type: research

Evaluating Imaging Biomarkers of Acquired Resistance to Targeted EGFR Therapy in Xenograft Models of Human Head and Neck Squamous Cell Carcinoma
Lauren C. J. Baker, Arti Sikka, Jonathan M. Price, Jessica K. R. Boult, Elise Y. Lepicard, Gary Box, Yann Jamin, Terry J. Spinks, Gabriela Kramer-Marek, Martin O. Leach, Suzanne A. Eccles, Carol Box, Simon P. Robinson (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 23, 2018 Category: Cancer & Oncology Source Type: research

Transgenic Mouse Models in Cancer Research
Ursa Lampreht Tratar, Simon Horvat, Maja Cemazar (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 20, 2018 Category: Cancer & Oncology Source Type: research

Lysine-Specific Demethylase 1A as a Promising Target in Acute Myeloid Leukemia
Daniela Magliulo, Rosa Bernardi, Samantha Messina (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - July 19, 2018 Category: Cancer & Oncology Source Type: research