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Sensation and Psychiatry: Linking Age-Related Hearing Loss to Late-Life Depression and Cognitive Decline.
Abstract Recent research has linked age-related hearing loss to impaired performance across cognitive domains and increased risk for dementia diagnosis. The data linking hearing impairment to incident late-life depression are more mixed but suggest that diminished hearing does increase risk for depression. Behavioral mechanisms may explain these associations, such as the withdrawal of older adults from situations in which they may have difficulty hearing and communicating, which may contribute to the development of social isolation, loneliness, and consequent cognitive decline and depression. At a neural level, ch...
Source: The American Journal of Psychiatry - December 5, 2017 Category: Psychiatry Authors: Rutherford BR, Brewster K, Golub JS, Kim AH, Roose SP Tags: Am J Psychiatry Source Type: research

Ketamine for Rapid Reduction of Suicidal Thoughts in Major Depression: A Midazolam-Controlled Randomized Clinical Trial.
CONCLUSIONS: Adjunctive ketamine demonstrated a greater reduction in clinically significant suicidal ideation in depressed patients within 24 hours compared with midazolam, partially independently of antidepressant effect. PMID: 29202655 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 5, 2017 Category: Psychiatry Authors: Grunebaum MF, Galfalvy HC, Choo TH, Keilp JG, Moitra VK, Parris MS, Marver JE, Burke AK, Milak MS, Sublette ME, Oquendo MA, Mann JJ Tags: Am J Psychiatry Source Type: research

Clinical and Cognitive Significance of Auditory Sensory Processing Deficits in Schizophrenia.
CONCLUSIONS: Impaired suppression of auditory stimuli was associated with core pathological features of schizophrenia, increasing confidence that P50 inhibitory processing can inform the development of interventions that target cognitive impairments in this chronic and debilitating mental illness. PMID: 29202656 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 5, 2017 Category: Psychiatry Authors: Hamilton HK, Williams TJ, Ventura J, Jasperse LJ, Owens EM, Miller GA, Subotnik KL, Nuechterlein KH, Yee CM Tags: Am J Psychiatry Source Type: research

Physician Mental Health and Well-Being: Research and Practiceedited by Kirk J. Brower, M.D., and Michelle B. Riba, M.D., M.S. New York, Springer, 2017, 326 pp., $69.99 (hardcover).
PMID: 29191026 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Summers RF Tags: Am J Psychiatry Source Type: research

Firearms Policy and Suicide Prevention.
PMID: 29191027 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Sung JC Tags: Am J Psychiatry Source Type: research

Reviewers for The American Journal of Psychiatry.
Authors: PMID: 29191028 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Tags: Am J Psychiatry Source Type: research

Facilitating Temporary, Safe Firearms Restrictions Among Individuals at High Risk of Suicide: Response to Sung.
PMID: 29191029 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Olfson M, Crystal S, Gerhard T Tags: Am J Psychiatry Source Type: research

Altered Sensory Phenomena Experienced in Bipolar Disorder.
PMID: 29191030 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Parker G, Paterson A, Romano M, Graham R Tags: Am J Psychiatry Source Type: research

BDNF, 5-HT, and Anxiety: Identification of a Critical Periadolescent Developmental Period.
PMID: 29191031 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Duman RS Tags: Am J Psychiatry Source Type: research

2017 in Review.
PMID: 29191032 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Freedman R, Lewis DA, Michels R, Pine DS, Rush AJ, Schultz SK, Tamminga CA, Katz R Tags: Am J Psychiatry Source Type: research

Joan of Arc-Hearing Voices.
PMID: 29191033 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Schildkrout B Tags: Am J Psychiatry Source Type: research

Correction.
CORRECTION. Am J Psychiatry. 2017 Dec 01;174(12):1225 Authors: PMID: 29191034 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Tags: Am J Psychiatry Source Type: research

Epigenetic Programming: A Putative Neurobiological Mechanism Linking Childhood Maltreatment and Risk for Adult Psychopathology.
PMID: 29191035 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: McKinney BC Tags: Am J Psychiatry Source Type: research

Gender Minority Stress, Depression, and Anxiety in a Transgender High School Student.
PMID: 29191036 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Davies RD, Kessel B Tags: Am J Psychiatry Source Type: research

The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directionsedited by Andr é F. Carvalho and Eduard Vieta. New York, Oxford University Press, 2017, 528 pp., $64.95 (paperback).
The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directionsedited by André F. Carvalho and Eduard Vieta. New York, Oxford University Press, 2017, 528 pp., $64.95 (paperback). Am J Psychiatry. 2017 Dec 01;174(12):1226 Authors: Freedman R PMID: 29191037 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Freedman R Tags: Am J Psychiatry Source Type: research

Disability Enrollment in a Community-Based Coordinated Specialty Care Program.
PMID: 29191038 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Humensky J, Scodes J, Wall M, Malinovsky I, Marino L, Smith T, Sederer L, Nossel I, Bello I, Dixon L Tags: Am J Psychiatry Source Type: research

Frontal Lobe Moderators and Mediators of Response to Exposure Therapy in PTSD.
PMID: 29191039 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Neylan TC Tags: Am J Psychiatry Source Type: research

The War on Terror: Is There Ever Room for Compassion?
PMID: 29191040 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2017 Category: Psychiatry Authors: Reda OA Tags: Am J Psychiatry Source Type: research

Rates and Predictors of Conversion to Schizophrenia or Bipolar Disorder Following Substance-Induced Psychosis.
CONCLUSIONS: Substance-induced psychosis is strongly associated with the development of severe mental illness, and a long follow-up period is needed to identify the majority of cases. PMID: 29179576 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 28, 2017 Category: Psychiatry Authors: Starzer MSK, Nordentoft M, Hjorthøj C Tags: Am J Psychiatry Source Type: research

Service Use Preceding Opioid-Related Fatality.
CONCLUSIONS: Persons dying of opioid-related causes, particularly those who were diagnosed with chronic pain conditions, commonly received services related to drug use disorders and mental disorders in the last year of life, though opioid use disorder diagnoses near the time of death were rare. PMID: 29179577 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 28, 2017 Category: Psychiatry Authors: Olfson M, Wall M, Wang S, Crystal S, Blanco C Tags: Am J Psychiatry Source Type: research

Impact of SSRI Therapy on Risk of Conversion From Mild Cognitive Impairment to Alzheimer's Dementia in Individuals With Previous Depression.
CONCLUSIONS: Long-term SSRI treatment may delay progression from MCI to Alzheimer's dementia. PMID: 29179578 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 28, 2017 Category: Psychiatry Authors: Bartels C, Wagner M, Wolfsgruber S, Ehrenreich H, Schneider A, Alzheimer’s Disease Neuroimaging Initiative Tags: Am J Psychiatry Source Type: research

A Population-Based Longitudinal Study of Symptoms and Signs Before the Onset of Psychosis.
CONCLUSIONS: In 18- to 21-year-olds, the presence of psychotic symptoms was associated with later hospitalization for a nonaffective psychotic disorder. However, the low positive predictive values of symptoms elicited in primary mental health care settings suggest that symptoms alone are not useful in predicting later hospitalization for nonaffective psychotic disorder. PMID: 29179579 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 28, 2017 Category: Psychiatry Authors: Livny A, Reichenberg A, Fruchter E, Yoffe R, Goldberg S, Fenchel D, Burshtein S, Bachar E, Davidson M, Weiser M Tags: Am J Psychiatry Source Type: research

Association of Hormonal Contraception With Suicide Attempts and Suicides.
CONCLUSIONS: Use of hormonal contraception was positively associated with subsequent suicide attempt and suicide. Adolescent women experienced the highest relative risk. PMID: 29145752 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 17, 2017 Category: Psychiatry Authors: Skovlund CW, Mørch LS, Kessing LV, Lange T, Lidegaard Ø Tags: Am J Psychiatry Source Type: research

The Neurodevelopmental Basis of Early Childhood Disruptive Behavior: Irritable and Callous Phenotypes as Exemplars.
Abstract The arrival of the Journal's 175th anniversary occurs at a time of recent advances in research, providing an ideal opportunity to present a neurodevelopmental roadmap for understanding, preventing, and treating psychiatric disorders. Such a roadmap is particularly relevant for early-childhood-onset neurodevelopmental conditions, which emerge when experience-dependent neuroplasticity is at its peak. Employing a novel developmental specification approach, this review places recent neurodevelopmental research on early childhood disruptive behavior within the historical context of the Journal. The authors hig...
Source: The American Journal of Psychiatry - November 17, 2017 Category: Psychiatry Authors: Wakschlag LS, Perlman SB, Blair RJ, Leibenluft E, Briggs-Gowan MJ, Pine DS Tags: Am J Psychiatry Source Type: research

Cortical and Subcortical Brain Morphometry Differences Between Patients With Autism Spectrum Disorder and Healthy Individuals Across the Lifespan: Results From the ENIGMA ASD Working Group.
CONCLUSIONS: The ENIGMA ASD working group provides the largest study of brain morphometry differences in ASD to date, using a well-established, validated, publicly available analysis pipeline. ASD patients showed altered morphometry in the cognitive and affective parts of the striatum, frontal cortex, and temporal cortex. Complex developmental trajectories were observed for the different regions, with a developmental peak around adolescence. These findings suggest an interplay in the abnormal development of the striatal, frontal, and temporal regions in ASD across the lifespan. PMID: 29145754 [PubMed - as supplied by ...
Source: The American Journal of Psychiatry - November 17, 2017 Category: Psychiatry Authors: van Rooij D, Anagnostou E, Arango C, Auzias G, Behrmann M, Busatto GF, Calderoni S, Daly E, Deruelle C, Di Martino A, Dinstein I, Duran FLS, Durston S, Ecker C, Fair D, Fedor J, Fitzgerald J, Freitag CM, Gallagher L, Gori I, Haar S, Hoekstra L, Jahanshad Tags: Am J Psychiatry Source Type: research

GERI-BD: A Randomized Double-Blind Controlled Trial of Lithium and Divalproex in the Treatment of Mania in Older Patients With Bipolar Disorder.
CONCLUSIONS: Both lithium and divalproex were adequately tolerated and efficacious; lithium was associated with a greater reduction in mania scores over 9 weeks. PMID: 29088928 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Young RC, Mulsant BH, Sajatovic M, Gildengers AG, Gyulai L, Al Jurdi RK, Beyer J, Evans J, Banerjee S, Greenberg R, Marino P, Kunik ME, Chen P, Barrett M, Schulberg HC, Bruce ML, Reynolds CF, Alexopoulos GS, GERI-BD Study Group Tags: Am J Psychiatry Source Type: research

The Danger of LeDoux and Pine's Two-System Framework for Fear.
PMID: 29088929 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Fanselow MS, Pennington ZT Tags: Am J Psychiatry Source Type: research

Copy Number Variation in Syndromic Forms of Psychiatric Illness: The Emerging Value of Clinical Genetic Testing in Psychiatry.
PMID: 29088930 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Bouwkamp CG, Kievit AJA, Markx S, Friedman JI, van Zutven L, van Minkelen R, Vrijenhoek T, Xu B, Sterrenburg-van de Nieuwegiessen I, Veltman JA, Bonifati V, Kushner SA Tags: Am J Psychiatry Source Type: research

Equivalence of Psychodynamic Therapy to Other Established Treatments: Limited Supporting Evidence and Clinical Relevance.
PMID: 29088931 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Cristea IA, Cuijpers P, Naudet F Tags: Am J Psychiatry Source Type: research

Long-Term Outcomes of Psychosis: Naturalistic Follow-Up After Initial Hospitalization.
PMID: 29088932 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Schooler NR Tags: Am J Psychiatry Source Type: research

Psychosis Beyond the 22q11.2 Deletion: Do Additional Genetic Factors Play a Role?
PMID: 29088933 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Goes FS, Sawa A Tags: Am J Psychiatry Source Type: research

Modern-Type Depression as an "Adjustment" Disorder in Japan: The Intersection of Collectivistic Society Encountering an Individualistic Performance-Based System.
Modern-Type Depression as an "Adjustment" Disorder in Japan: The Intersection of Collectivistic Society Encountering an Individualistic Performance-Based System. Am J Psychiatry. 2017 Nov 01;174(11):1051-1053 Authors: Kato TA, Kanba S PMID: 29088934 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Kato TA, Kanba S Tags: Am J Psychiatry Source Type: research

The Importance of Identifying Characteristics Underlying the Vulnerability to Develop Alcohol Use Disorder.
PMID: 29088935 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Petrakis IL Tags: Am J Psychiatry Source Type: research

Elevating the Role of Subjective Experience in the Clinic: Response to Fanselow and Pennington.
PMID: 29088936 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Pine DS, LeDoux JE Tags: Am J Psychiatry Source Type: research

Telepsychiatry and Health Technologies: A Guide for Mental Health Professionalsedited by Peter Yellowlees, M.B.B.S., M.D., and Jay H. Shore, M.D., M.P.H. Washington, D.C., American Psychiatric Association Publishing, 2018, 400 pp., $69.00 (paperback).
PMID: 29088937 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Brown FW Tags: Am J Psychiatry Source Type: research

Integrating Behavioral Health and Primary Careedited by Robert E. Feinstein, Joseph V. Connelly, and Marilyn S. Feinstein. New York, Oxford University Press, 2017, 592 pp., $89.95 (hardcover).
PMID: 29088938 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Katz RB, Cherry BM Tags: Am J Psychiatry Source Type: research

Different Standards When Assessing the Evidence for Psychodynamic Therapy? Response to Cristea et al.
PMID: 29088939 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Steinert C, Munder T, Rabung S, Hoyer J, Leichsenring F Tags: Am J Psychiatry Source Type: research

Treatment of Bipolar Disorder in the Elderly.
PMID: 29088940 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Authors: Dunner DL Tags: Am J Psychiatry Source Type: research

Correction.
CORRECTION. Am J Psychiatry. 2017 Nov 01;174(11):1126 Authors: PMID: 29088941 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2017 Category: Psychiatry Tags: Am J Psychiatry Source Type: research

Effect of Early-Life Fluoxetine on Anxiety-Like Behaviors in BDNF Val66Met Mice.
CONCLUSIONS: These findings suggest that SSRI administration during a "sensitive period" during periadolescence leads to long-lasting anxiolytic effects in a genetic mouse model of elevated anxiety-like behaviors. These persistent effects highlight the role of BDNF in the maturation of the serotonin system and the capacity to enhance its development through a pharmacological intervention. PMID: 29084453 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 31, 2017 Category: Psychiatry Authors: Dincheva I, Yang J, Li A, Marinic T, Freilingsdorf H, Huang C, Casey BJ, Hempstead B, Glatt CE, Lee FS, Bath KG, Jing D Tags: Am J Psychiatry Source Type: research

Altered Brain Developmental Trajectories in Adolescents After Initiating Drinking.
CONCLUSIONS: Initiation of drinking during adolescence, with or without marijuana co-use, disordered normal brain growth trajectories. Factors possibly contributing to abnormal cortical volume trajectories include peak consumption in the past year and family history of alcoholism. PMID: 29084454 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 31, 2017 Category: Psychiatry Authors: Pfefferbaum A, Kwon D, Brumback T, Thompson WK, Cummins K, Tapert SF, Brown SA, Colrain IM, Baker FC, Prouty D, De Bellis MD, Clark DB, Nagel BJ, Chu W, Park SH, Pohl KM, Sullivan EV Tags: Am J Psychiatry Source Type: research

Transgender Research in the 21st Century: A Selective Critical Review From a Neurocognitive Perspective.
Abstract Gender dysphoria describes the psychological distress caused by identifying with the sex opposite to the one assigned at birth. In recent years, much progress has been made in characterizing the needs of transgender persons wishing to transition to their preferred gender, thus helping to optimize care. This critical review of the literature examines their common mental health issues, several individual risk factors for psychiatric comorbidity, and current research on the underlying neurobiology. Prevalence rates of persons identifying as transgender and seeking help with transition have been rising steepl...
Source: The American Journal of Psychiatry - October 20, 2017 Category: Psychiatry Authors: Mueller SC, De Cuypere G, T'Sjoen G Tags: Am J Psychiatry Source Type: research

Late-Onset ADHD Reconsidered With Comprehensive Repeated Assessments Between Ages 10 and 25.
CONCLUSIONS: Individuals seeking treatment for late-onset ADHD may be valid cases; however, more commonly, symptoms represent nonimpairing cognitive fluctuations, a comorbid disorder, or the cognitive effects of substance use. False positive late-onset ADHD cases are common without careful assessment. Clinicians should carefully assess impairment, psychiatric history, and substance use before treating potential late-onset cases. PMID: 29050505 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 20, 2017 Category: Psychiatry Authors: Sibley MH, Rohde LA, Swanson JM, Hechtman LT, Molina BSG, Mitchell JT, Arnold LE, Caye A, Kennedy TM, Roy A, Stehli A, Multimodal Treatment Study of Children with ADHD (MTA) Cooperative Group Tags: Am J Psychiatry Source Type: research

Adjunctive Bright Light Therapy for Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Trial.
CONCLUSIONS: The data from this study provide robust evidence that supports the efficacy of midday bright light therapy for bipolar depression. PMID: 28969438 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 3, 2017 Category: Psychiatry Authors: Sit DK, McGowan J, Wiltrout C, Diler RS, Dills JJ, Luther J, Yang A, Ciolino JD, Seltman H, Wisniewski SR, Terman M, Wisner KL Tags: Am J Psychiatry Source Type: research

Improving the Efficiency of Psychotherapy for Depression: Computer-Assisted Versus Standard CBT.
CONCLUSIONS: The study findings indicate that a method of CCBT that blends Internet-delivered skill-building modules with about 5 hours of therapeutic contact was noninferior to a conventional course of CBT that provided over 8 additional hours of therapist contact. Future studies should focus on dissemination and optimizing therapist support methods to maximize the public health significance of CCBT. PMID: 28969439 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 3, 2017 Category: Psychiatry Authors: Thase ME, Wright JH, Eells TD, Barrett MS, Wisniewski SR, Balasubramani GK, McCrone P, Brown GK Tags: Am J Psychiatry Source Type: research

Exercise and the Prevention of Depression: Results of the HUNT Cohort Study.
CONCLUSIONS: Regular leisure-time exercise of any intensity provides protection against future depression but not anxiety. Relatively modest changes in population levels of exercise may have important public mental health benefits and prevent a substantial number of new cases of depression. PMID: 28969440 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 3, 2017 Category: Psychiatry Authors: Harvey SB, Øverland S, Hatch SL, Wessely S, Mykletun A, Hotopf M Tags: Am J Psychiatry Source Type: research

The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis.
CONCLUSIONS: Ketamine rapidly reduced suicidal thoughts, within 1 day and for up to 1 week in depressed patients with suicidal ideation. Ketamine's effects on suicidal ideation were partially independent of its effects on mood, although subsequent trials in transdiagnostic samples are required to confirm that ketamine exerts a specific effect on suicidal ideation. Additional research on ketamine's long-term safety and its efficacy in reducing suicide risk is needed before clinical implementation. PMID: 28969441 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 3, 2017 Category: Psychiatry Authors: Wilkinson ST, Ballard ED, Bloch MH, Mathew SJ, Murrough JW, Feder A, Sos P, Wang G, Zarate CA, Sanacora G Tags: Am J Psychiatry Source Type: research

Psychiatric Genomics: An Update and an Agenda.
rtium Abstract The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of psychiatry. This global effort is dedicated to rapid progress and open science, and in the past decade it has delivered an increasing flow of new knowledge about the fundamental basis of common psychiatric disorders. The PGC has recently commenced a program of research designed to deliver "actionable" findings-genomic results that 1) reveal fundamental biology, 2) inform clinical practice, and 3) deliver new therapeutic targets. The central idea of the PGC is to convert the family history risk factor into...
Source: The American Journal of Psychiatry - October 3, 2017 Category: Psychiatry Authors: Sullivan PF, Agrawal A, Bulik CM, Andreassen OA, Børglum AD, Breen G, Cichon S, Edenberg HJ, Faraone SV, Gelernter J, Mathews CA, Nievergelt CM, Smoller JW, O'Donovan MC, Psychiatric Genomics Consortium Tags: Am J Psychiatry Source Type: research

Are Personality Disorders Assessed in Young People?
PMID: 28965457 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2017 Category: Psychiatry Authors: Conway CC, Tackett JL, Skodol AE Tags: Am J Psychiatry Source Type: research

What About Fetal Alcohol Exposure?
PMID: 28965458 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2017 Category: Psychiatry Authors: Bell CC, Chimata R Tags: Am J Psychiatry Source Type: research