In the grip of SARS-CoV-2: The scientific leadership of the Colombian Instituto Nacional de Salud
Biomedica. 2021 Jun 29;41(2):195-200.NO ABSTRACTPMID:34214259 | PMC:PMC8341952 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Luis Alberto G ómez-Grosso Marcela Mercado Martha Luc ía Ospina Source Type: research

Epidermolysis bullosa with pyloric atresia: Report of two cases in consecutive siblings
We present two cases of consecutive siblings with this condition and fatal outcomes in both of them. We made a review of the literature and discussed the main topics.PMID:34214260 | PMC:PMC8372840 | DOI:10.7705/biomedica.5401 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Katherine M árquez Diego Andr és Rodríguez Luis Alfonso P érez Mauricio Duarte Luis Augusto Z árate Source Type: research

Leptospirosis and rickettsiosis, a diagnostic challenge for febrile syndrome in endemic areas
Biomedica. 2021 Jun 29;41(2):208-217. doi: 10.7705/biomedica.5598.ABSTRACTThis is the case of a 50-year-old male from the region of Urabá, Colombia, with a mixed infection by Rickettsia rickettsii and Leptospira interrogans serovar Copenhageni ST78 and negative test for malaria and dengue fever. The patient presented with febrile syndrome and was unresponsive to systemic antibiotic treatment, who finally died in the intensive care unit. We established the postmortem diagnosis through molecular typification of the two etiological agents. In the inspection at the patient’s home, we found a Rattus rattus specimen...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Ren é Ramírez-García Juan Carlos Quintero Aixa Paola Rosado Margarita Arboleda V íctor Alejandro González Piedad Agudelo-Fl órez Source Type: research

Cranial complications of otitis media with paralysis of the contralateral sixth cranial pair in pediatrics
We report the case of a 9-year-old girl with no disease history who presented with otitis media, otorrhea, intracranial hypertension syndrome, and paralysis of the VI cranial nerve contralateral to the lesion. A computed tomography scan of the skull and a brain magnetic resonance imaging revealed chronic otomastoiditis, petrous apicitis, and thrombosis of the transverse and sigmoid sinus, the jugular bulb, and the right internal jugular vein. She received antibiotics and surgical treatment. This case shows the spectrum of intra and extracranial complications associated with acute otitis media in the antibiotic era. The phy...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Luz Miriam Leiva Hamilton Delgado Leidy Viviana Holgu ín Christian Rojas Source Type: research

Fatal reversible cerebral vasoconstriction syndrome: An unusual presentation of a rare disease
We describe the case of a 49-year-old woman who presented with headaches, visual symptoms, and seizures. Three days after admission, vasoconstriction areas were found in at least two vascular territories in two segments of the same arteries. The patient was admitted to the intensive care unit where her blood pressure was monitored and she received medical treatment. Surprisingly, the patient presented an unpredicted evolution in developing malignant cerebral edema on the seventh day after admission. She then suffered brain death and was taken to organ donation. A guided nervous system necropsy was later performed. The path...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Hern án Bayona Mar ía Camila Valencia Ang élica Peña Natalia Ram írez Carlos Mart ínez Source Type: research

Exogenous pigmentation by silver nitrate: Dermatological and toxicological aspects, case report
We report the case of a male patient from Medellín, Colombia, with a family history of melanoma and the presence of these lesions throughout his body.PMID:34214264 | PMC:PMC8390001 | DOI:10.7705/biomedica.5876 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Ángela Londoño Camila P érez Rodrigo Restrepo Nathalie Morales Miguel Mart ínez Daniela Morales Source Type: research

An 18-year-old man with tropical verrucous syndrome: Leishmaniasis or sporotrichosis?
We present an 18-year-old man with extensive verrucous plaques in one knee interpreted by clinic, epidemiology, and biopsy as verrucous cutaneous leishmaniasis. He was treated with Glucantime® for 20 days without improvement. A new biopsy was made that was also interpreted as cutaneous leishmaniasis. The revision of both biopsies showed inflammation with abscessed granulomas and asteroid sporotrichotic bodies at the center of the granulomas that led to the diagnosis of sporotrichosis later confirmed by the fungus culture. The patient responded to the treatment with itraconazole. As clinical and epidemiological findings...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Paola Mac ías Juliana Ord óñez Claudia M Arenas Gerza ín Rodríguez Source Type: research

Seroprevalence of arboviruses in Ecuador: Implications for improved surveillance
CONCLUSIONS: The results show a YFV vaccination history and suggest the activity of arboviruses not included in the current surveillance scheme. Enhanced arbovirus and mosquito surveillance, as well as continued YFV vaccination and evaluation of its coverage/effectiveness, are recommended.PMID:34214266 | PMC:PMC8382292 | DOI:10.7705/biomedica.5623 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Ernesto Guti érrez-Vera Leandro Pati ño Martha Castillo-Segovia V íctor Mora-Valencia Julio Montesdeoca-Agurto Mary Regato-Arrata Source Type: research

Seroprevalence of Brucella canis in canines from a dog shelter in Bogot á, Colombia
Conclusions: The seroprevalence determined in this study represented by a single dog with anti-B. canis IgG can be considered a potential risk both for canine and human populations since this single dog could have a persistent infection capable of spreading the bacteria.PMID:34214267 | PMC:PMC8375667 | DOI:10.7705/biomedica.5409 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Astrid-Jullieth Laverde Daniela Restrepo-Botero Diego Hern ández-Pulido Jos é Luis Rodríguez-Bautista Isabel-Sof ía Sandoval Source Type: research

Inequalities in dental prenatal control in Colombia: An analysis based on the IV National Oral Health Study, 2013-2014
Conclusions: In Colombia, the effective provision of dental control to pregnant women as part of comprehensive prenatal care continues to be a challenge. Significant efforts are required to comply with regulations and reduce social inequalities in access to this service.PMID:34214268 | PMC:PMC8386945 | DOI:10.7705/biomedica.5705 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Lorena Alexandra Maldonado-Maldonado Sandra Patricia Misnaza-Castrill ón Carlos Andr és Castañeda-Orjuela Source Type: research

Importance of determining variations in the number of copies in newborns with autosomal aneuploidies
Conclusions: Although the number of analyzed individuals was small, it is important to highlight that we found other variants in the number of copies that have been described in association with neurodevelopmental disorders, congenital anomalies, deafness, and short/tall stature, among others, in almost half of them, which will probably impact the phenotype negatively in patients with aneuploidies.PMID:34214269 | PMC:PMC8387016 | DOI:10.7705/biomedica.5354 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Hugo Abarca Milana Trubnykova F élix Chavesta Marco Ord óñez Evelina Rond ón Source Type: research

In-hospital complications in an acute care geriatric unit
Conclusion: In acute care centers, integral assessment at admission to identify functional dependence and malnutrition predicts in-hospital complications.PMID:34214270 | PMC:PMC8382119 | DOI:10.7705/biomedica.5664 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: David Jos é Coca Sandra Milena Castelblanco Diego Andr és Chavarro-Carvajal Luis Carlos Venegas-Sanabria Source Type: research

Cytogenetic risk groups for childhood acute myeloid leukemia based on survival analysis in a cancer referral hospital from Per ú
Conclusion: Two groups of cytogenetic risk were determined: high (or unfavorable) and standard (favorable).PMID:34214271 | PMC:PMC8382291 | DOI:10.7705/biomedica.5747 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Yesica Llimpe Source Type: research

Snakebite biomedical and epidemiological aspects in the department of Cauca, Colombia, 2009-2018
Conclusions: El Tambo and Piamonte municipalities, being male, and rural areas were the variables most affected by ophidism, mainly bothropic ophidism. The highest incidences occurred in the southern part of Cauca, in the Patía and Caquetá river basins.PMID:34214272 | PMC:PMC8388738 | DOI:10.7705/biomedica.5853 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Mar ía José Sevilla-Sánchez Santiago Ayerbe-Gonz ález Eliana Bola ños-Bolaños Source Type: research

Streptococcus pneumoniae serotype 3 genotypes in invasive isolates from Colombia
CONCLUSION: In Colombia, the pneumococcal population of the capsular type 3 shows a continuous and homogeneous circulation relating to the clonal group ST-180.PMID:34214273 | PMC:PMC8387017 | DOI:10.7705/biomedica.5407 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Zonia Katerin Alarc ón Carolina Duarte Olga Sanabria Jaime Moreno Source Type: research

Ixodes tropicalis (Acari: Ixodidae) infesting a human and molecular detection of Rickettsia bellii, Colombia
CONCLUSION: This is the first report in Colombia of a species of the Ixodes genus parasitizing a human and the first report of the detection of R. bellii in this tick species.PMID:34214274 | PMC:PMC8384465 | DOI:10.7705/biomedica.5464 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Juan Carlos Quintero Mar ía L Félix Jos é M Venzal Santiago Nava Source Type: research

Rediscovering the chikungunya virus
Biomedica. 2021 Jun 29;41(2):353-373. doi: 10.7705/biomedica.5797.ABSTRACTThe chikungunya virus (CHIKV) is an Alphavirus that belongs to the Old World group. These arthritogenic viruses cause a febrile illness characterized by arthralgias and myalgias. Although fatal cases during CHIKV infection are rare, the disease may be disabling and generate a broad spectrum of atypical manifestations, such as cardiovascular, respiratory, eye, kidney, and skin complications, among others. When joint pain persists for three or more months, it results in the chronic form of the disease called post-chikungunya chronic inflammatory rheuma...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Eliana Patricia Calvo Edwin Dar ío Archila Lady L ópez Jaime Eduardo Castellanos Source Type: research

Letter to the editor "Prognostic factors in hospitalized patients diagnosed with SARS-CoV-2 infection, Bogot á, Colombia"
Biomedica. 2021 Jun 29;41(2):374-377.NO ABSTRACTPMID:34214276 | PMC:PMC8387015 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Cristian Antony Ramos-Vera Juan Camilo Motta Source Type: research

RT-qPCR diagnosis in state public health laboratories as determinants of performance of public health surveillance during the pandemic
Biomedica. 2021 Jun 29;41(2):378-379.NO ABSTRACTPMID:34214277 | PMC:PMC8386688 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Alvaro Javier Idrovo Jos é Moreno-Montoya Source Type: research

In the grip of SARS-CoV-2: The scientific leadership of the Colombian Instituto Nacional de Salud
Biomedica. 2021 Jun 29;41(2):195-200.NO ABSTRACTPMID:34214259 | PMC:PMC8341952 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Luis Alberto G ómez-Grosso Marcela Mercado Martha Luc ía Ospina Source Type: research

Epidermolysis bullosa with pyloric atresia: Report of two cases in consecutive siblings
We present two cases of consecutive siblings with this condition and fatal outcomes in both of them. We made a review of the literature and discussed the main topics.PMID:34214260 | PMC:PMC8372840 | DOI:10.7705/biomedica.5401 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Katherine M árquez Diego Andr és Rodríguez Luis Alfonso P érez Mauricio Duarte Luis Augusto Z árate Source Type: research

Leptospirosis and rickettsiosis, a diagnostic challenge for febrile syndrome in endemic areas
Biomedica. 2021 Jun 29;41(2):208-217. doi: 10.7705/biomedica.5598.ABSTRACTThis is the case of a 50-year-old male from the region of Urabá, Colombia, with a mixed infection by Rickettsia rickettsii and Leptospira interrogans serovar Copenhageni ST78 and negative test for malaria and dengue fever. The patient presented with febrile syndrome and was unresponsive to systemic antibiotic treatment, who finally died in the intensive care unit. We established the postmortem diagnosis through molecular typification of the two etiological agents. In the inspection at the patient’s home, we found a Rattus rattus specimen...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Ren é Ramírez-García Juan Carlos Quintero Aixa Paola Rosado Margarita Arboleda V íctor Alejandro González Piedad Agudelo-Fl órez Source Type: research

Cranial complications of otitis media with paralysis of the contralateral sixth cranial pair in pediatrics
We report the case of a 9-year-old girl with no disease history who presented with otitis media, otorrhea, intracranial hypertension syndrome, and paralysis of the VI cranial nerve contralateral to the lesion. A computed tomography scan of the skull and a brain magnetic resonance imaging revealed chronic otomastoiditis, petrous apicitis, and thrombosis of the transverse and sigmoid sinus, the jugular bulb, and the right internal jugular vein. She received antibiotics and surgical treatment. This case shows the spectrum of intra and extracranial complications associated with acute otitis media in the antibiotic era. The phy...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Luz Miriam Leiva Hamilton Delgado Leidy Viviana Holgu ín Christian Rojas Source Type: research

Fatal reversible cerebral vasoconstriction syndrome: An unusual presentation of a rare disease
We describe the case of a 49-year-old woman who presented with headaches, visual symptoms, and seizures. Three days after admission, vasoconstriction areas were found in at least two vascular territories in two segments of the same arteries. The patient was admitted to the intensive care unit where her blood pressure was monitored and she received medical treatment. Surprisingly, the patient presented an unpredicted evolution in developing malignant cerebral edema on the seventh day after admission. She then suffered brain death and was taken to organ donation. A guided nervous system necropsy was later performed. The path...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Hern án Bayona Mar ía Camila Valencia Ang élica Peña Natalia Ram írez Carlos Mart ínez Source Type: research

Exogenous pigmentation by silver nitrate: Dermatological and toxicological aspects, case report
We report the case of a male patient from Medellín, Colombia, with a family history of melanoma and the presence of these lesions throughout his body.PMID:34214264 | PMC:PMC8390001 | DOI:10.7705/biomedica.5876 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Ángela Londoño Camila P érez Rodrigo Restrepo Nathalie Morales Miguel Mart ínez Daniela Morales Source Type: research

An 18-year-old man with tropical verrucous syndrome: Leishmaniasis or sporotrichosis?
We present an 18-year-old man with extensive verrucous plaques in one knee interpreted by clinic, epidemiology, and biopsy as verrucous cutaneous leishmaniasis. He was treated with Glucantime® for 20 days without improvement. A new biopsy was made that was also interpreted as cutaneous leishmaniasis. The revision of both biopsies showed inflammation with abscessed granulomas and asteroid sporotrichotic bodies at the center of the granulomas that led to the diagnosis of sporotrichosis later confirmed by the fungus culture. The patient responded to the treatment with itraconazole. As clinical and epidemiological findings...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Paola Mac ías Juliana Ord óñez Claudia M Arenas Gerza ín Rodríguez Source Type: research

Seroprevalence of arboviruses in Ecuador: Implications for improved surveillance
CONCLUSIONS: The results show a YFV vaccination history and suggest the activity of arboviruses not included in the current surveillance scheme. Enhanced arbovirus and mosquito surveillance, as well as continued YFV vaccination and evaluation of its coverage/effectiveness, are recommended.PMID:34214266 | PMC:PMC8382292 | DOI:10.7705/biomedica.5623 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Ernesto Guti érrez-Vera Leandro Pati ño Martha Castillo-Segovia V íctor Mora-Valencia Julio Montesdeoca-Agurto Mary Regato-Arrata Source Type: research

Seroprevalence of Brucella canis in canines from a dog shelter in Bogot á, Colombia
Conclusions: The seroprevalence determined in this study represented by a single dog with anti-B. canis IgG can be considered a potential risk both for canine and human populations since this single dog could have a persistent infection capable of spreading the bacteria.PMID:34214267 | PMC:PMC8375667 | DOI:10.7705/biomedica.5409 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Astrid-Jullieth Laverde Daniela Restrepo-Botero Diego Hern ández-Pulido Jos é Luis Rodríguez-Bautista Isabel-Sof ía Sandoval Source Type: research

Inequalities in dental prenatal control in Colombia: An analysis based on the IV National Oral Health Study, 2013-2014
Conclusions: In Colombia, the effective provision of dental control to pregnant women as part of comprehensive prenatal care continues to be a challenge. Significant efforts are required to comply with regulations and reduce social inequalities in access to this service.PMID:34214268 | PMC:PMC8386945 | DOI:10.7705/biomedica.5705 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Lorena Alexandra Maldonado-Maldonado Sandra Patricia Misnaza-Castrill ón Carlos Andr és Castañeda-Orjuela Source Type: research

Importance of determining variations in the number of copies in newborns with autosomal aneuploidies
Conclusions: Although the number of analyzed individuals was small, it is important to highlight that we found other variants in the number of copies that have been described in association with neurodevelopmental disorders, congenital anomalies, deafness, and short/tall stature, among others, in almost half of them, which will probably impact the phenotype negatively in patients with aneuploidies.PMID:34214269 | PMC:PMC8387016 | DOI:10.7705/biomedica.5354 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Hugo Abarca Milana Trubnykova F élix Chavesta Marco Ord óñez Evelina Rond ón Source Type: research

In-hospital complications in an acute care geriatric unit
Conclusion: In acute care centers, integral assessment at admission to identify functional dependence and malnutrition predicts in-hospital complications.PMID:34214270 | PMC:PMC8382119 | DOI:10.7705/biomedica.5664 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: David Jos é Coca Sandra Milena Castelblanco Diego Andr és Chavarro-Carvajal Luis Carlos Venegas-Sanabria Source Type: research

Cytogenetic risk groups for childhood acute myeloid leukemia based on survival analysis in a cancer referral hospital from Per ú
Conclusion: Two groups of cytogenetic risk were determined: high (or unfavorable) and standard (favorable).PMID:34214271 | PMC:PMC8382291 | DOI:10.7705/biomedica.5747 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Yesica Llimpe Source Type: research

Snakebite biomedical and epidemiological aspects in the department of Cauca, Colombia, 2009-2018
Conclusions: El Tambo and Piamonte municipalities, being male, and rural areas were the variables most affected by ophidism, mainly bothropic ophidism. The highest incidences occurred in the southern part of Cauca, in the Patía and Caquetá river basins.PMID:34214272 | PMC:PMC8388738 | DOI:10.7705/biomedica.5853 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Mar ía José Sevilla-Sánchez Santiago Ayerbe-Gonz ález Eliana Bola ños-Bolaños Source Type: research

Streptococcus pneumoniae serotype 3 genotypes in invasive isolates from Colombia
CONCLUSION: In Colombia, the pneumococcal population of the capsular type 3 shows a continuous and homogeneous circulation relating to the clonal group ST-180.PMID:34214273 | PMC:PMC8387017 | DOI:10.7705/biomedica.5407 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Zonia Katerin Alarc ón Carolina Duarte Olga Sanabria Jaime Moreno Source Type: research

Ixodes tropicalis (Acari: Ixodidae) infesting a human and molecular detection of Rickettsia bellii, Colombia
CONCLUSION: This is the first report in Colombia of a species of the Ixodes genus parasitizing a human and the first report of the detection of R. bellii in this tick species.PMID:34214274 | PMC:PMC8384465 | DOI:10.7705/biomedica.5464 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Juan Carlos Quintero Mar ía L Félix Jos é M Venzal Santiago Nava Source Type: research

Rediscovering the chikungunya virus
Biomedica. 2021 Jun 29;41(2):353-373. doi: 10.7705/biomedica.5797.ABSTRACTThe chikungunya virus (CHIKV) is an Alphavirus that belongs to the Old World group. These arthritogenic viruses cause a febrile illness characterized by arthralgias and myalgias. Although fatal cases during CHIKV infection are rare, the disease may be disabling and generate a broad spectrum of atypical manifestations, such as cardiovascular, respiratory, eye, kidney, and skin complications, among others. When joint pain persists for three or more months, it results in the chronic form of the disease called post-chikungunya chronic inflammatory rheuma...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Eliana Patricia Calvo Edwin Dar ío Archila Lady L ópez Jaime Eduardo Castellanos Source Type: research

Letter to the editor "Prognostic factors in hospitalized patients diagnosed with SARS-CoV-2 infection, Bogot á, Colombia"
Biomedica. 2021 Jun 29;41(2):374-377.NO ABSTRACTPMID:34214276 | PMC:PMC8387015 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Cristian Antony Ramos-Vera Juan Camilo Motta Source Type: research

RT-qPCR diagnosis in state public health laboratories as determinants of performance of public health surveillance during the pandemic
Biomedica. 2021 Jun 29;41(2):378-379.NO ABSTRACTPMID:34214277 | PMC:PMC8386688 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Alvaro Javier Idrovo Jos é Moreno-Montoya Source Type: research

In the grip of SARS-CoV-2: The scientific leadership of the Colombian Instituto Nacional de Salud
Biomedica. 2021 Jun 29;41(2):195-200.NO ABSTRACTPMID:34214259 | PMC:PMC8341952 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Luis Alberto G ómez-Grosso Marcela Mercado Martha Luc ía Ospina Source Type: research

Epidermolysis bullosa with pyloric atresia: Report of two cases in consecutive siblings
We present two cases of consecutive siblings with this condition and fatal outcomes in both of them. We made a review of the literature and discussed the main topics.PMID:34214260 | PMC:PMC8372840 | DOI:10.7705/biomedica.5401 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Katherine M árquez Diego Andr és Rodríguez Luis Alfonso P érez Mauricio Duarte Luis Augusto Z árate Source Type: research

Leptospirosis and rickettsiosis, a diagnostic challenge for febrile syndrome in endemic areas
Biomedica. 2021 Jun 29;41(2):208-217. doi: 10.7705/biomedica.5598.ABSTRACTThis is the case of a 50-year-old male from the region of Urabá, Colombia, with a mixed infection by Rickettsia rickettsii and Leptospira interrogans serovar Copenhageni ST78 and negative test for malaria and dengue fever. The patient presented with febrile syndrome and was unresponsive to systemic antibiotic treatment, who finally died in the intensive care unit. We established the postmortem diagnosis through molecular typification of the two etiological agents. In the inspection at the patient’s home, we found a Rattus rattus specimen...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Ren é Ramírez-García Juan Carlos Quintero Aixa Paola Rosado Margarita Arboleda V íctor Alejandro González Piedad Agudelo-Fl órez Source Type: research

Cranial complications of otitis media with paralysis of the contralateral sixth cranial pair in pediatrics
We report the case of a 9-year-old girl with no disease history who presented with otitis media, otorrhea, intracranial hypertension syndrome, and paralysis of the VI cranial nerve contralateral to the lesion. A computed tomography scan of the skull and a brain magnetic resonance imaging revealed chronic otomastoiditis, petrous apicitis, and thrombosis of the transverse and sigmoid sinus, the jugular bulb, and the right internal jugular vein. She received antibiotics and surgical treatment. This case shows the spectrum of intra and extracranial complications associated with acute otitis media in the antibiotic era. The phy...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Luz Miriam Leiva Hamilton Delgado Leidy Viviana Holgu ín Christian Rojas Source Type: research

Fatal reversible cerebral vasoconstriction syndrome: An unusual presentation of a rare disease
We describe the case of a 49-year-old woman who presented with headaches, visual symptoms, and seizures. Three days after admission, vasoconstriction areas were found in at least two vascular territories in two segments of the same arteries. The patient was admitted to the intensive care unit where her blood pressure was monitored and she received medical treatment. Surprisingly, the patient presented an unpredicted evolution in developing malignant cerebral edema on the seventh day after admission. She then suffered brain death and was taken to organ donation. A guided nervous system necropsy was later performed. The path...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Hern án Bayona Mar ía Camila Valencia Ang élica Peña Natalia Ram írez Carlos Mart ínez Source Type: research

Exogenous pigmentation by silver nitrate: Dermatological and toxicological aspects, case report
We report the case of a male patient from Medellín, Colombia, with a family history of melanoma and the presence of these lesions throughout his body.PMID:34214264 | PMC:PMC8390001 | DOI:10.7705/biomedica.5876 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Ángela Londoño Camila P érez Rodrigo Restrepo Nathalie Morales Miguel Mart ínez Daniela Morales Source Type: research

An 18-year-old man with tropical verrucous syndrome: Leishmaniasis or sporotrichosis?
We present an 18-year-old man with extensive verrucous plaques in one knee interpreted by clinic, epidemiology, and biopsy as verrucous cutaneous leishmaniasis. He was treated with Glucantime® for 20 days without improvement. A new biopsy was made that was also interpreted as cutaneous leishmaniasis. The revision of both biopsies showed inflammation with abscessed granulomas and asteroid sporotrichotic bodies at the center of the granulomas that led to the diagnosis of sporotrichosis later confirmed by the fungus culture. The patient responded to the treatment with itraconazole. As clinical and epidemiological findings...
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Paola Mac ías Juliana Ord óñez Claudia M Arenas Gerza ín Rodríguez Source Type: research

Seroprevalence of arboviruses in Ecuador: Implications for improved surveillance
CONCLUSIONS: The results show a YFV vaccination history and suggest the activity of arboviruses not included in the current surveillance scheme. Enhanced arbovirus and mosquito surveillance, as well as continued YFV vaccination and evaluation of its coverage/effectiveness, are recommended.PMID:34214266 | PMC:PMC8382292 | DOI:10.7705/biomedica.5623 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Ernesto Guti érrez-Vera Leandro Pati ño Martha Castillo-Segovia V íctor Mora-Valencia Julio Montesdeoca-Agurto Mary Regato-Arrata Source Type: research

Seroprevalence of Brucella canis in canines from a dog shelter in Bogot á, Colombia
Conclusions: The seroprevalence determined in this study represented by a single dog with anti-B. canis IgG can be considered a potential risk both for canine and human populations since this single dog could have a persistent infection capable of spreading the bacteria.PMID:34214267 | PMC:PMC8375667 | DOI:10.7705/biomedica.5409 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Astrid-Jullieth Laverde Daniela Restrepo-Botero Diego Hern ández-Pulido Jos é Luis Rodríguez-Bautista Isabel-Sof ía Sandoval Source Type: research

Inequalities in dental prenatal control in Colombia: An analysis based on the IV National Oral Health Study, 2013-2014
Conclusions: In Colombia, the effective provision of dental control to pregnant women as part of comprehensive prenatal care continues to be a challenge. Significant efforts are required to comply with regulations and reduce social inequalities in access to this service.PMID:34214268 | PMC:PMC8386945 | DOI:10.7705/biomedica.5705 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Lorena Alexandra Maldonado-Maldonado Sandra Patricia Misnaza-Castrill ón Carlos Andr és Castañeda-Orjuela Source Type: research

Importance of determining variations in the number of copies in newborns with autosomal aneuploidies
Conclusions: Although the number of analyzed individuals was small, it is important to highlight that we found other variants in the number of copies that have been described in association with neurodevelopmental disorders, congenital anomalies, deafness, and short/tall stature, among others, in almost half of them, which will probably impact the phenotype negatively in patients with aneuploidies.PMID:34214269 | PMC:PMC8387016 | DOI:10.7705/biomedica.5354 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: Hugo Abarca Milana Trubnykova F élix Chavesta Marco Ord óñez Evelina Rond ón Source Type: research

In-hospital complications in an acute care geriatric unit
Conclusion: In acute care centers, integral assessment at admission to identify functional dependence and malnutrition predicts in-hospital complications.PMID:34214270 | PMC:PMC8382119 | DOI:10.7705/biomedica.5664 (Source: Biomedica : Revista del Instituto Nacional de Salud)
Source: Biomedica : Revista del Instituto Nacional de Salud - July 2, 2021 Category: International Medicine & Public Health Authors: David Jos é Coca Sandra Milena Castelblanco Diego Andr és Chavarro-Carvajal Luis Carlos Venegas-Sanabria Source Type: research