Plant-Pollinator Specialization: Origin and Measurement of Curvature
Am Nat. 2022 Feb;199(2):206-222. doi: 10.1086/717677. Epub 2021 Dec 8.ABSTRACTAbstractA feature of biodiversity is the abundance of curves displayed by organs and organisms. Curvature is a widespread, convergent trait that has important ecological and evolutionary implications. In pollination ecology, the curvature of flowers and pollinator mouthparts (e.g., hummingbird bills) along the dorsiventral plane has been associated with specialization, competition, and species coexistence. Six differing methods have historically been used to measure curvature in pollination systems; we provide a solution to this inconsistency by ...
Source: The American Naturalist - January 25, 2022 Category: Biology Authors: Mannfred M A Boehm Jill E Jankowski Quentin C B Cronk Source Type: research
Icariin inhibits isoproterenol-induced cardiomyocyte hypertropic injury through activating autophagy via the AMPK/mTOR signaling pathway
In conclusion, these findings indicated that ICA attenuated cardiomyocyte hypertrophy induced by ISO and prevented cell injury, and the specific mechanism was mediated by AMPK/mTOR pathway to enhance autophagy and reduce autophagy-related cardiomyocyte apoptosis.PMID:35063771 | DOI:10.1016/j.bbrc.2022.01.029 (Source: Biochemical and Biophysical Research communications)
Source: Biochemical and Biophysical Research communications - January 22, 2022 Category: Biochemistry Authors: Lin Hu Ziyuan Wang Huan Li Jiarui Wei Fengyue Tang Qing Wang Jing Wang Xiaoqiao Zhang Qiufang Zhang Source Type: research
Icariin inhibits isoproterenol-induced cardiomyocyte hypertropic injury through activating autophagy via the AMPK/mTOR signaling pathway
In conclusion, these findings indicated that ICA attenuated cardiomyocyte hypertrophy induced by ISO and prevented cell injury, and the specific mechanism was mediated by AMPK/mTOR pathway to enhance autophagy and reduce autophagy-related cardiomyocyte apoptosis.PMID:35063771 | DOI:10.1016/j.bbrc.2022.01.029 (Source: Cell Research)
Source: Cell Research - January 22, 2022 Category: Cytology Authors: Lin Hu Ziyuan Wang Huan Li Jiarui Wei Fengyue Tang Qing Wang Jing Wang Xiaoqiao Zhang Qiufang Zhang Source Type: research
Icariin inhibits isoproterenol-induced cardiomyocyte hypertropic injury through activating autophagy via the AMPK/mTOR signaling pathway
In conclusion, these findings indicated that ICA attenuated cardiomyocyte hypertrophy induced by ISO and prevented cell injury, and the specific mechanism was mediated by AMPK/mTOR pathway to enhance autophagy and reduce autophagy-related cardiomyocyte apoptosis.PMID:35063771 | DOI:10.1016/j.bbrc.2022.01.029 (Source: Biochemical and Biophysical Research communications)
Source: Biochemical and Biophysical Research communications - January 22, 2022 Category: Biochemistry Authors: Lin Hu Ziyuan Wang Huan Li Jiarui Wei Fengyue Tang Qing Wang Jing Wang Xiaoqiao Zhang Qiufang Zhang Source Type: research
Epimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16
Cell Death & Disease, Published online: 20 January 2022; doi:10.1038/s41419-021-04435-8Epimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16 (Source: Cell death and disease)
Source: Cell death and disease - January 20, 2022 Category: Internal Medicine Authors: Haiyang Zhao Tingting Zhao Jihong Yang Qianqian Huang Hua Wu Yueyun Pan Hui Wang Yun Qian Source Type: research
Antiviral activity of Epimedium koreanum Nakai water extract against influenza viruses
Biomed Pharmacother. 2021 Dec 26;146:112581. doi: 10.1016/j.biopha.2021.112581. Online ahead of print.ABSTRACTEpimedium koreanum Nakai (EKN) is a popular plant in Korean and Chinese medicine for treating a variety of ailments. The aqueous extract of EKN has a significant inhibitory impact on influenza A virus (IAV) infection by directly blocking viral attachment and having a virucidal effect, according to this study. Using fluorescent microscopy and fluorescence-activated cell sorting (FACS) with a green fluorescent protein (GFP)-tagged Influenza A/PR/8/34 virus, we examined the effect of EKN on viral infection. By viral i...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - December 29, 2021 Category: Drugs & Pharmacology Authors: Won-Kyung Cho Jin Yeul Ma Source Type: research
Antiviral activity of Epimedium koreanum Nakai water extract against influenza viruses
Biomed Pharmacother. 2021 Dec 26;146:112581. doi: 10.1016/j.biopha.2021.112581. Online ahead of print.ABSTRACTEpimedium koreanum Nakai (EKN) is a popular plant in Korean and Chinese medicine for treating a variety of ailments. The aqueous extract of EKN has a significant inhibitory impact on influenza A virus (IAV) infection by directly blocking viral attachment and having a virucidal effect, according to this study. Using fluorescent microscopy and fluorescence-activated cell sorting (FACS) with a green fluorescent protein (GFP)-tagged Influenza A/PR/8/34 virus, we examined the effect of EKN on viral infection. By viral i...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - December 29, 2021 Category: Drugs & Pharmacology Authors: Won-Kyung Cho Jin Yeul Ma Source Type: research
Preliminary screening of the potential active ingredients in traditional Chinese medicines using the Ussing chamber model combined with HPLC-PDA-MS
J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Dec 22;1189:123090. doi: 10.1016/j.jchromb.2021.123090. Online ahead of print.ABSTRACTAn in vitro intestinal absorption model combined with high-performance liquid chromatography-photo diode array-tandem mass spectrometry (HPLC-PDA-MS) was used for preliminary screening of potential active ingredients from complex multi-component traditional Chinese medicine (TCM) system. Oral administration is one of the main administration methods for TCMs. Only the ingredients that could be absorbed have the opportunity to play a role. Thus, these were defined as potential active ingre...
Source: Anal Sci - December 27, 2021 Category: Chemistry Authors: Dandan Wang Rui Liu Jinxiang Zeng Chunhu Li Wei Xiang Guoyue Zhong Zhining Xia Source Type: research
Preliminary screening of the potential active ingredients in traditional Chinese medicines using the Ussing chamber model combined with HPLC-PDA-MS
J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Dec 22;1189:123090. doi: 10.1016/j.jchromb.2021.123090. Online ahead of print.ABSTRACTAn in vitro intestinal absorption model combined with high-performance liquid chromatography-photo diode array-tandem mass spectrometry (HPLC-PDA-MS) was used for preliminary screening of potential active ingredients from complex multi-component traditional Chinese medicine (TCM) system. Oral administration is one of the main administration methods for TCMs. Only the ingredients that could be absorbed have the opportunity to play a role. Thus, these were defined as potential active ingre...
Source: Anal Sci - December 27, 2021 Category: Chemistry Authors: Dandan Wang Rui Liu Jinxiang Zeng Chunhu Li Wei Xiang Guoyue Zhong Zhining Xia Source Type: research
Protective effects of icariin on traumatic brain injury
CONCLUSION: The present study demonstrates that ICA may be a promising therapeutic strategy for reducing inflammation in TBI.PMID:34951380 | DOI:10.2174/1567202619666211223125628 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - December 24, 2021 Category: Neurology Authors: Anni Du Rui Cai Jingshan Shi Qin Wu Source Type: research
Protective effects of icariin on traumatic brain injury
CONCLUSION: The present study demonstrates that ICA may be a promising therapeutic strategy for reducing inflammation in TBI.PMID:34951380 | DOI:10.2174/1567202619666211223125628 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - December 24, 2021 Category: Neurology Authors: Anni Du Rui Cai Jingshan Shi Qin Wu Source Type: research
Protective effects of icariin on traumatic brain injury
CONCLUSION: The present study demonstrates that ICA may be a promising therapeutic strategy for reducing inflammation in TBI.PMID:34951380 | DOI:10.2174/1567202619666211223125628 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - December 24, 2021 Category: Neurology Authors: Anni Du Rui Cai Jingshan Shi Qin Wu Source Type: research
Protective effects of icariin on traumatic brain injury
CONCLUSION: The present study demonstrates that ICA may be a promising therapeutic strategy for reducing inflammation in TBI.PMID:34951380 | DOI:10.2174/1567202619666211223125628 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - December 24, 2021 Category: Neurology Authors: Anni Du Rui Cai Jingshan Shi Qin Wu Source Type: research
Protective effects of icariin on traumatic brain injury
CONCLUSION: The present study demonstrates that ICA may be a promising therapeutic strategy for reducing inflammation in TBI.PMID:34951380 | DOI:10.2174/1567202619666211223125628 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - December 24, 2021 Category: Neurology Authors: Anni Du Rui Cai Jingshan Shi Qin Wu Source Type: research
Protective effects of icariin on traumatic brain injury
CONCLUSION: The present study demonstrates that ICA may be a promising therapeutic strategy for reducing inflammation in TBI.PMID:34951380 | DOI:10.2174/1567202619666211223125628 (Source: Current Neurovascular Research)
Source: Current Neurovascular Research - December 24, 2021 Category: Neurology Authors: Anni Du Rui Cai Jingshan Shi Qin Wu Source Type: research
