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Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN
Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTENLong noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN, Published online: 15 February 2018; doi:10.1038/s41419-018-0305-7Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Qidi Zheng Zhuojia Lin Jie Xu Yanan Lu Qiuyu Meng Chen Wang Yuxin Yang Xiaoru Xin Xiaonan Li Hu Pu Xin Gui Tianming Li Wujun Xiong Dongdong Lu Source Type: research

Meeting Report: The 8th Barossa Meeting—Cell Signaling in Cancer Medicine in the Barossa Valley, Australia
Meeting Report: The 8th Barossa Meeting—Cell Signaling in Cancer Medicine in the Barossa Valley, AustraliaMeeting Report: The 8th Barossa Meeting—Cell Signaling in Cancer Medicine in the Barossa Valley, Australia, Published online: 15 February 2018; doi:10.1038/s41419-018-0285-7Meeting Report: The 8th Barossa Meeting—Cell Signaling in Cancer Medicine in the Barossa Valley, Australia (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Guillermo A. Gomez Joanna M. Woodcock Vinay Tergaonkar Philip A. Gregory Source Type: research

Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1/H3K9me3 signaling pathway
Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1/H3K9me3 signaling pathway, Published online: 15 February 2018; doi:10.1038/s41419-018-0297-3Norisoboldine, a natural AhR agonist, promotes Treg differentiation and attenuates colitis via targeting glycolysis and subsequent NAD+/SIRT1/SUV39H1/H3K9me3 signaling pathway (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Qi Lv Kai Wang Simiao Qiao Ling Yang Yirong Xin Yue Dai Zhifeng Wei Source Type: research

CAR-T cells: the long and winding road to solid tumors
CAR-T cells: the long and winding road to solid tumors, Published online: 15 February 2018; doi:10.1038/s41419-018-0278-6CAR-T cells: the long and winding road to solid tumors (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Maria Michela D ’Aloia Ilaria Grazia Zizzari Benedetto Sacchetti Luca Pierelli Maurizio Alimandi Source Type: research

CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing
CRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing, Published online: 15 February 2018; doi:10.1038/s41419-018-0301-yCRISPR whole-genome screening identifies new necroptosis regulators and RIPK1 alternative splicing (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Marinella G. Callow Colin Watanabe Katherine E. Wickliffe Russell Bainer Sarah Kummerfield Julie Weng Trinna Cuellar Vasantharajan Janakiraman Honglin Chen Ben Chih Yuxin Liang Benjamin Haley Kim Newton Michael R. Costa Source Type: research

Gambogenic acid inhibits fibroblast growth factor receptor signaling pathway in erlotinib-resistant non-small-cell lung cancer and suppresses patient-derived xenograft growth
Gambogenic acid inhibits fibroblast growth factor receptor signaling pathway in erlotinib-resistant non-small-cell lung cancer and suppresses patient-derived xenograft growth, Published online: 15 February 2018; doi:10.1038/s41419-018-0314-6Gambogenic acid inhibits fibroblast growth factor receptor signaling pathway in erlotinib-resistant non-small-cell lung cancer and suppresses patient-derived xenograft growth (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Linfeng Xu Xiaoxiao Meng Naihan Xu Wenwei Fu Hongsheng Tan Li Zhang Qianjun Zhou Jianan Qian Shiwei Tu Xueting Li Yuanzhi Lao Hongxi Xu Source Type: research

ALS-related human cortical and motor neurons survival is differentially affected by Sema3A
ALS-related human cortical and motor neurons survival is differentially affected by Sema3A, Published online: 15 February 2018; doi:10.1038/s41419-018-0294-6ALS-related human cortical and motor neurons survival is differentially affected by Sema3A (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Anastasya Birger Miri Ottolenghi Liat Perez Benjamin Reubinoff Oded Behar Source Type: research

Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer
Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer, Published online: 15 February 2018; doi:10.1038/s41419-018-0330-6Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Yang-An Wen Xiaopeng Xiong Yekaterina Y. Zaytseva Dana L. Napier Emma Vallee Austin T. Li Chi Wang Heidi L. Weiss B. Mark Evers Tianyan Gao Source Type: research

Predictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liver cirrhosis
Predictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liver cirrhosis, Published online: 15 February 2018; doi:10.1038/s41419-018-0308-4Predictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liver cirrhosis (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Xiaoli Yang Yan Liu Menghui Li Hao Wu Yunbing Wang Yu You Peizhi Li Xiong Ding Chang ’an Liu Jianping Gong Source Type: research

NIT1 suppresses tumour proliferation by activating the TGFβ1–Smad2/3 signalling pathway in colorectal cancer
NIT1 suppresses tumour proliferation by activating the TGFβ1–Smad2/3 signalling pathway in colorectal cancerNIT1 suppresses tumour proliferation by activating the TGFβ1–Smad2/3 signalling pathway in colorectal cancer, Published online: 15 February 2018; doi:10.1038/s41419-018-0333-3NIT1 suppresses tumour proliferation by activating the TGFβ1–Smad2/3 signalling pathway in colorectal cancer (Source: Cell death and disease)
Source: Cell death and disease - February 15, 2018 Category: Internal Medicine Authors: Chun Lin Jianming Zhang Yanxia Lu Xiaomin Li Wenjuan Zhang Wei Zhang Weihao Lin Lin Zheng Xuenong Li Source Type: research

Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis
Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis, Published online: 14 February 2018; doi:10.1038/s41419-018-0288-4Interleukin 4 modulates microglia homeostasis and attenuates the early slowly progressive phase of amyotrophic lateral sclerosis (Source: Cell death and disease)
Source: Cell death and disease - February 14, 2018 Category: Internal Medicine Authors: Chiara Rossi Melania Cusimano Martina Zambito Annamaria Finardi Alessia Capotondo Jose Manuel Garcia-Manteiga Giancarlo Comi Roberto Furlan Gianvito Martino Luca Muzio Source Type: research

Heterogeneity and cell fate flux in single human pancreatic islet cells
Heterogeneity and cell fate flux in single human pancreatic islet cells, Published online: 14 February 2018; doi:10.1038/s41419-018-0269-7Heterogeneity and cell fate flux in single human pancreatic islet cells (Source: Cell death and disease)
Source: Cell death and disease - February 14, 2018 Category: Internal Medicine Authors: Natasha H. J. Ng Adrian K. K. Teo Source Type: research

Rage induces hepatocellular carcinoma proliferation and sorafenib resistance by modulating autophagy
Rage induces hepatocellular carcinoma proliferation and sorafenib resistance by modulating autophagy, Published online: 14 February 2018; doi:10.1038/s41419-018-0329-zRage induces hepatocellular carcinoma proliferation and sorafenib resistance by modulating autophagy (Source: Cell death and disease)
Source: Cell death and disease - February 14, 2018 Category: Internal Medicine Authors: Jun Li Peng-Wen Wu Yuan Zhou Bo Dai Peng-Fei Zhang Yu-Hen Zhang Yang Liu Xiao-Lei Shi Source Type: research

Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma
Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma, Published online: 14 February 2018; doi:10.1038/s41419-018-0265-yLong non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma (Source: Cell death and disease)
Source: Cell death and disease - February 14, 2018 Category: Internal Medicine Authors: Yi He Yizhou Jing Fang Wei Yanyan Tang Liting Yang Jia Luo Pei Yang Qianxi Ni Jinmeng Pang Qianjin Liao Fang Xiong Can Guo Bo Xiang Xiaoling Li Ming Zhou Yong Li Wei Xiong Zhaoyang Zeng Guiyuan Li Source Type: research

Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy
Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy, Published online: 14 February 2018; doi:10.1038/s41419-018-0336-0Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy (Source: Cell death and disease)
Source: Cell death and disease - February 14, 2018 Category: Internal Medicine Authors: Valentina Celestini Tugsan Tezil Luciana Russo Candida Fasano Paola Sanese Giovanna Forte Alessia Peserico Martina Lepore Signorile Giovanna Longo Domenico De Rasmo Anna Signorile Raffaella Maria Gadaleta Natasha Scialpi Mineko Terao Enrico Garattini Tizi Source Type: research

Lup-20(29)-en-3β,28-di-yl-nitrooxy acetate affects MCF-7 proliferation through the crosstalk between apoptosis and autophagy in mitochondria
Lup-20(29)-en-3β,28-di-yl-nitrooxy acetate affects MCF-7 proliferation through the crosstalk between apoptosis and autophagy in mitochondriaLup-20(29)-en-3β,28-di-yl-nitrooxy acetate affects MCF-7 proliferation through the crosstalk between apoptosis and autophagy in mitochondria, Published online: 14 February 2018; doi:10.1038/s41419-017-0255-5Lup-20(29)-en-3β,28-di-yl-nitrooxy acetate affects MCF-7 proliferation through the crosstalk between apoptosis and autophagy in mitochondria (Source: Cell death and disease)
Source: Cell death and disease - February 14, 2018 Category: Internal Medicine Authors: Xiaoning Yan Lei Yang Gaili Feng Zhuli Yu Minjie Xiao Weibin Cai Yanmei Xing Shasha Bai Junqia Guo Zhiyu Wang Tao Wang Rong Zhang Source Type: research

Dural effects of oxidative stress on cardiomyogenesis via Gata4 transcription and protein ubiquitination
Dural effects of oxidative stress on cardiomyogenesis via Gata4 transcription and protein ubiquitination, Published online: 14 February 2018; doi:10.1038/s41419-018-0281-yDural effects of oxidative stress on cardiomyogenesis via Gata4 transcription and protein ubiquitination (Source: Cell death and disease)
Source: Cell death and disease - February 14, 2018 Category: Internal Medicine Authors: Tao Li Xia Zhang Kesheng Jiang Jing Liu Zhiqiang Liu Source Type: research

The long non-coding RNA FOXD2-AS1 promotes bladder cancer progression and recurrence through a positive feedback loop with Akt and E2F1
The long non-coding RNA FOXD2-AS1 promotes bladder cancer progression and recurrence through a positive feedback loop with Akt and E2F1, Published online: 14 February 2018; doi:10.1038/s41419-018-0275-9The long non-coding RNA FOXD2-AS1 promotes bladder cancer progression and recurrence through a positive feedback loop with Akt and E2F1 (Source: Cell death and disease)
Source: Cell death and disease - February 14, 2018 Category: Internal Medicine Authors: Feng Su Wang He Changhao Chen Mo Liu Hongwei Liu Feiyuan Xue Junming Bi Dawei Xu Yue Zhao Jian Huang Tianxin Lin Chun Jiang Source Type: research

Human umbilical cord mesenchymal stem cell-derived extracellular vesicles promote lung adenocarcinoma growth by transferring miR-410
Human umbilical cord mesenchymal stem cell-derived extracellular vesicles promote lung adenocarcinoma growth by transferring miR-410, Published online: 13 February 2018; doi:10.1038/s41419-018-0323-5Human umbilical cord mesenchymal stem cell-derived extracellular vesicles promote lung adenocarcinoma growth by transferring miR-410 (Source: Cell death and disease)
Source: Cell death and disease - February 13, 2018 Category: Internal Medicine Authors: Liyang Dong Yanan Pu Lina Zhang Qianqian Qi Lei Xu Wei Li Chuan Wei Xiaofan Wang Sha Zhou Jifeng Zhu Xuefeng Wang Feng Liu Xiaojun Chen Chuan Su Source Type: research

Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity
Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity, Published online: 13 February 2018; doi:10.1038/s41419-017-0065-9Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity (Source: Cell death and disease)
Source: Cell death and disease - February 13, 2018 Category: Internal Medicine Authors: Elaine Lai Han Leung Lian Xiang Luo Zhong Qiu Liu Vincent Kam Wai Wong Lin Lin Lu Ying Xie Ni Zhang Yuan Qing Qu Xing Xing Fan Ying Li Min Huang Dai Kai Xiao Jun Huang Yan Ling Zhou Jian Xing He Jian Ding Xiao Jun Yao David C. Ward Liang Liu Source Type: research

KRAS induces lung tumorigenesis through microRNAs modulation
KRAS induces lung tumorigenesis through microRNAs modulation, Published online: 13 February 2018; doi:10.1038/s41419-017-0243-9KRAS induces lung tumorigenesis through microRNAs modulation (Source: Cell death and disease)
Source: Cell death and disease - February 13, 2018 Category: Internal Medicine Authors: Lei Shi Justin Middleton Young-Jun Jeon Peter Magee Dario Veneziano Alessandro Lagan à Hui-Sun Leong Sudhakar Sahoo Matteo Fassan Richard Booton Rajesh Shah Philip A. J. Crosbie Michela Garofalo Source Type: research

Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer
Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer, Published online: 13 February 2018; doi:10.1038/s41419-017-0092-6Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer (Source: Cell death and disease)
Source: Cell death and disease - February 13, 2018 Category: Internal Medicine Authors: Amer Alasadi Michael Chen G. V. T. Swapna Hanlin Tao Jingjing Guo Juan Collantes Noor Fadhil Gaetano T. Montelione Shengkan Jin Source Type: research

Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling
Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling, Published online: 13 February 2018; doi:10.1038/s41419-017-0223-0Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling (Source: Cell death and disease)
Source: Cell death and disease - February 13, 2018 Category: Internal Medicine Authors: Zhou Wang Lingman Ma Mengqi Su Yiran Zhou Ke Mao Chengqin Li Guangyong Peng Changlin Zhou Baiyong Shen Jie Dou Source Type: research

MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop
MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loopMiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop, Published online: 12 February 2018; doi:10.1038/s41419-017-0206-1MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop (Source: Cell death and disease)
Source: Cell death and disease - February 12, 2018 Category: Internal Medicine Authors: Mingjie Xu Jiangfeng Li Xiao Wang Shuai Meng Jiaying Shen Song Wang Xin Xu Bo Xie Ben Liu Liping Xie Source Type: research

Mechanical stretch-induced osteogenic differentiation of human jaw bone marrow mesenchymal stem cells (hJBMMSCs) via inhibition of the NF-κB pathway
Mechanical stretch-induced osteogenic differentiation of human jaw bone marrow mesenchymal stem cells (hJBMMSCs) via inhibition of the NF-κB pathwayMechanical stretch-induced osteogenic differentiation of human jaw bone marrow mesenchymal stem cells (hJBMMSCs) via inhibition of the NF-κB pathway, Published online: 12 February 2018; doi:10.1038/s41419-018-0279-5Mechanical stretch-induced osteogenic differentiation of human jaw bone marrow mesenchymal stem cells (hJBMMSCs) via inhibition of the NF-κB pathway (Source: Cell death and disease)
Source: Cell death and disease - February 12, 2018 Category: Internal Medicine Authors: Xiaoyan Chen Yuan Liu Wanghui Ding Jiejun Shi Shenglai Li Yali Liu Mengjie Wu Huiming Wang Source Type: research

Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat
Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat, Published online: 12 February 2018; doi:10.1038/s41419-017-0217-yGlucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat (Source: Cell death and disease)
Source: Cell death and disease - February 12, 2018 Category: Internal Medicine Authors: Jian Chen Jun-Jun Xie Ke-Si Shi Yun-Tao Gu Cong-Cong Wu Jun Xuan Yue Ren Long Chen Yao-Sen Wu Xiao-Lei Zhang Jian Xiao De-Zhong Wang Xiang-Yang Wang Source Type: research

Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+ exchanger 3 downregulation
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+ exchanger 3 downregulation, Published online: 12 February 2018; doi:10.1038/s41419-017-0227-9Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+ exchanger 3 downregulation (Source: Cell death and disease)
Source: Cell death and disease - February 12, 2018 Category: Internal Medicine Authors: Serenella Anzilotti Paola Brancaccio Giuseppe Simeone Valeria Valsecchi Antonio Vinciguerra Agnese Secondo Tiziana Petrozziello Natascia Guida Rossana Sirabella Ornella Cuomo Pasquale Cepparulo Andr è Herchuelz Salvatore Amoroso Gianfranco Di Renzo Lucio Source Type: research

Glutamine metabolism regulates FLIP expression and sensitivity to TRAIL in triple-negative breast cancer cells
Glutamine metabolism regulates FLIP expression and sensitivity to TRAIL in triple-negative breast cancer cells, Published online: 12 February 2018; doi:10.1038/s41419-018-0263-0Glutamine metabolism regulates FLIP expression and sensitivity to TRAIL in triple-negative breast cancer cells (Source: Cell death and disease)
Source: Cell death and disease - February 12, 2018 Category: Internal Medicine Authors: Marta Mauro-Lizcano Abelardo L ópez-Rivas Source Type: research

Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson’s disease
Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson’s diseaseDopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson’s disease, Published online: 12 February 2018; doi:10.1038/s41419-017-0221-2Dopamine D2 receptor-mediated neuroprotection in a G2019S Lrrk2 genetic model of Parkinson’s disease (Source: Cell death and disease)
Source: Cell death and disease - February 12, 2018 Category: Internal Medicine Authors: Alessandro Tozzi Michela Tantucci Saverio Marchi Petra Mazzocchetti Michele Morari Paolo Pinton Andrea Mancini Paolo Calabresi Source Type: research

Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival
Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival, Published online: 12 February 2018; doi:10.1038/s41419-017-0242-xAutophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival (Source: Cell death and disease)
Source: Cell death and disease - February 12, 2018 Category: Internal Medicine Authors: Lian Wang Zhouchun Shang Yang Zhou Xinyu Hu Yihong Chen Yantao Fan Xiaoyu Wei Liang Wu Qiujuan Liang Jun Zhang Zhengliang Gao Source Type: research

Association of cytosolic sialidase Neu2 with plasma membrane enhances Fas-mediated apoptosis by impairing PI3K-Akt/mTOR-mediated pathway in pancreatic cancer cells
Association of cytosolic sialidase Neu2 with plasma membrane enhances Fas-mediated apoptosis by impairing PI3K-Akt/mTOR-mediated pathway in pancreatic cancer cells, Published online: 12 February 2018; doi:10.1038/s41419-017-0191-4Association of cytosolic sialidase Neu2 with plasma membrane enhances Fas-mediated apoptosis by impairing PI3K-Akt/mTOR-mediated pathway in pancreatic cancer cells (Source: Cell death and disease)
Source: Cell death and disease - February 12, 2018 Category: Internal Medicine Authors: Shalini Nath Chhabinath Mandal Uttara Chatterjee Chitra Mandal Source Type: research

Temozolomide–perillyl alcohol conjugate downregulates O6-methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer
Temozolomide–perillyl alcohol conjugate downregulates O6-methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancerTemozolomide–perillyl alcohol conjugate downregulates O6-methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer, Published online: 09 February 2018; doi:10.1038/s41419-017-0193-2Temozolomide–perillyl alcohol conjugate downregulates O6-methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer (Source: Cell death and disease)
Source: Cell death and disease - February 9, 2018 Category: Internal Medicine Authors: Xingguo Song Li Xie Minghui Chang Xinran Geng Xingwu Wang Thomas C. Chen Xianrang Song Source Type: research

Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux
Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux, Published online: 08 February 2018; doi:10.1038/s41419-017-0190-5Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux (Source: Cell death and disease)
Source: Cell death and disease - February 8, 2018 Category: Internal Medicine Authors: Anupama Rai Pankaj Kumar Singh Virender Singh Vipendra Kumar Rohit Mishra Ashwani Kumar Thakur Anita Mahadevan Susarla Krishna Shankar Nihar Ranjan Jana Subramaniam Ganesh Source Type: research

Alterations of specific chromatin conformation affect ATRA-induced leukemia cell differentiation
Alterations of specific chromatin conformation affect ATRA-induced leukemia cell differentiation, Published online: 08 February 2018; doi:10.1038/s41419-017-0173-6Alterations of specific chromatin conformation affect ATRA-induced leukemia cell differentiation (Source: Cell death and disease)
Source: Cell death and disease - February 8, 2018 Category: Internal Medicine Authors: Yanjian Li Yi He Zhengyu Liang Yang Wang Fengling Chen Mohamed Nadhir Djekidel Guipeng Li Xu Zhang Shuqin Xiang Zejun Wang Juntao Gao Michael Q. Zhang Yang Chen Source Type: research

miR-27b-3p inhibits proliferation and potentially reverses multi-chemoresistance by targeting CBLB/GRB2 in breast cancer cells
miR-27b-3p inhibits proliferation and potentially reverses multi-chemoresistance by targeting CBLB/GRB2 in breast cancer cells, Published online: 07 February 2018; doi:10.1038/s41419-017-0211-4miR-27b-3p inhibits proliferation and potentially reverses multi-chemoresistance by targeting CBLB/GRB2 in breast cancer cells (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: Danni Chen Wengong Si Jiaying Shen Chengyong Du Weiyang Lou Chang Bao Huilin Zheng Jie Pan Guansheng Zhong Liang Xu Peifen Fu Weimin Fan Source Type: research

Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy
Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapyRegulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy, Published online: 07 February 2018; doi:10.1038/s41419-017-0209-yRegulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: M élanie Le Duff Julien Gouju Barbara Jonch ère Jordan Guillon Bertrand Toutain Alice Boissard C écile Henry Catherine Guette Eric Leli èvre Olivier Coqueret Source Type: research

Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β production
Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β productionCombination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β production, Published online: 07 February 2018; doi:10.1038/s41419-017-0194-1Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β production (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: Anthony C Tang Seyed M Rahavi Shan-Yu Fung Henry Y Lu Hong Yang Chinten J Lim Gregor S Reid Stuart E Turvey Source Type: research

Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state
Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state, Published online: 07 February 2018; doi:10.1038/s41419-017-0236-8Plasma Hemopexin ameliorates murine spinal cord injury by switching microglia from the M1 state to the M2 state (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: Dunxin Han Zhongwang Yu Weili Liu Dou Yin Yingyan Pu Jifeng Feng Yimin Yuan Aijun Huang Li Cao Cheng He Source Type: research

Homocysteine activates autophagy by inhibition of CFTR expression via interaction between DNA methylation and H3K27me3 in mouse liver
Homocysteine activates autophagy by inhibition of CFTR expression via interaction between DNA methylation and H3K27me3 in mouse liver, Published online: 07 February 2018; doi:10.1038/s41419-017-0216-zHomocysteine activates autophagy by inhibition of CFTR expression via interaction between DNA methylation and H3K27me3 in mouse liver (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: Anning Yang Yun Jiao Songhao Yang Mei Deng Xiaoling Yang Caiyan Mao Yue Sun Ning Ding Nan Li Minghao Zhang Shaoju Jin Huiping Zhang Yideng Jiang Source Type: research

Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth
Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth, Published online: 07 February 2018; doi:10.1038/s41419-017-0196-zOncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: Chao Zhou Hongwei Sun Chen Zheng Jing Gao Qingzi Fu Nianqi Hu Xiaoli Shao Yingying Zhou Jingting Xiong Ke Nie Huaibin Zhou Lijun Shen Hezhi Fang Jianxin Lyu Source Type: research

Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling
Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling, Published online: 07 February 2018; doi:10.1038/s41419-017-0230-1Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: Hong-Jin Zhao Christian Klausen Yan Li Hua Zhu Yan-Ling Wang Peter C. K. Leung Source Type: research

Regenerative potential of tonsil mesenchymal stem cells on surgical cutaneous defect
Regenerative potential of tonsil mesenchymal stem cells on surgical cutaneous defect, Published online: 07 February 2018; doi:10.1038/s41419-017-0248-4Regenerative potential of tonsil mesenchymal stem cells on surgical cutaneous defect (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: Sung-Chan Shin Yoojin Seo Hee Young Park Da-Woon Jung Tae-Hoon Shin Haejin Son Young Keum Kim Jin-Choon Lee Eui-Suk Sung Jeon Yeob Jang Hyung-Sik Kim Byung-Joo Lee Source Type: research

bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats
bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats, Published online: 07 February 2018; doi:10.1038/s41419-017-0229-7bFGF plays a neuroprotective role by suppressing excessive autophagy and apoptosis after transient global cerebral ischemia in rats (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: Dawei Sun Wenying Wang Xintao Wang Yan Wang Xiaotao Xu Feng Ping Yu Du Wei Jiang Derong Cui Source Type: research

Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death
Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death, Published online: 07 February 2018; doi:10.1038/s41419-017-0252-8Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death (Source: Cell death and disease)
Source: Cell death and disease - February 7, 2018 Category: Internal Medicine Authors: Stefano Thellung Beatrice Scoti Alessandro Corsaro Valentina Villa Mario Nizzari Maria Cristina Gagliani Carola Porcile Claudio Russo Aldo Pagano Carlo Tacchetti Katia Cortese Tullio Florio Source Type: research

Notch1 is a prognostic factor that is distinctly activated in the classical and proneural subtype of glioblastoma and that promotes glioma cell survival via the NF-κB(p65) pathway
Notch1 is a prognostic factor that is distinctly activated in the classical and proneural subtype of glioblastoma and that promotes glioma cell survival via the NF-κB(p65) pathwayNotch1 is a prognostic factor that is distinctly activated in the classical and proneural subtype of glioblastoma and that promotes glioma cell survival via the NF-κB(p65) pathway, Published online: 06 February 2018; doi:10.1038/s41419-017-0119-zNotch1 is a prognostic factor that is distinctly activated in the classical and proneural subtype of glioblastoma and that promotes glioma cell survival via the NF-κB(p65) pathway (Source...
Source: Cell death and disease - February 6, 2018 Category: Internal Medicine Authors: Long Hai Chen Zhang Tao Li Xingchen Zhou Bo Liu Shuai Li Meng Zhu Yu Lin Shengping Yu Kai Zhang Bingcheng Ren Haolang Ming Yubao Huang Lei Chen Pengfei Zhao Hua Zhou Tao Jiang Xuejun Yang Source Type: research

Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo
Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo, Published online: 06 February 2018; doi:10.1038/s41419-017-0166-5Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo (Source: Cell death and disease)
Source: Cell death and disease - February 6, 2018 Category: Internal Medicine Authors: Kangmao Huang Yanyan Chen Rui Zhang Yizheng Wu Yan Ma Xiangqian Fang Shuying Shen Source Type: research

Mesenchymal stem cells over-expressing cxcl12 enhance the radioresistance of the small intestine
Mesenchymal stem cells over-expressing cxcl12 enhance the radioresistance of the small intestine, Published online: 05 February 2018; doi:10.1038/s41419-017-0222-1Mesenchymal stem cells over-expressing cxcl12 enhance the radioresistance of the small intestine (Source: Cell death and disease)
Source: Cell death and disease - February 5, 2018 Category: Internal Medicine Authors: Pengyu Chang Boyin Zhang Lihong Shao Wei Song Weiyan Shi Libo Wang Tiankai Xu Dong Li Xiuzhu Gao Yaqin Qu Lihua Dong Jin Wang Source Type: research

Beclin1 circulating levels and accelerated aging markers in COPD
Beclin1 circulating levels and accelerated aging markers in COPD, Published online: 05 February 2018; doi:10.1038/s41419-017-0178-1Beclin1 circulating levels and accelerated aging markers in COPD (Source: Cell death and disease)
Source: Cell death and disease - February 5, 2018 Category: Internal Medicine Authors: Fr édéric Schlemmer Laurent Boyer Thibaud Soumagne Audrey Ridoux Christos Chouaid Bernard Maitre Sophie Lanone Serge Adnot Etienne Audureau Jorge Boczkowski Source Type: research

Nicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA
Nicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA, Published online: 02 February 2018; doi:10.1038/s41419-017-0224-zNicotine associated breast cancer in smokers is mediated through high level of EZH2 expression which can be reversed by methyltransferase inhibitor DZNepA (Source: Cell death and disease)
Source: Cell death and disease - February 2, 2018 Category: Internal Medicine Authors: Kanchan Kumari Biswajit Das Amit Adhya Sanjib Chaudhary Shantibhusan Senapati Sandip K. Mishra Source Type: research

Cooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9
Cooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9, Published online: 02 February 2018; doi:10.1038/s41419-017-0240-zCooperation between Hsp90 and mortalin/GRP75 in resistance to cell death induced by complement C5b-9 (Source: Cell death and disease)
Source: Cell death and disease - February 2, 2018 Category: Internal Medicine Authors: Perri Rozenberg Lea Ziporen Dana Gancz Moran Saar-Ray Zvi Fishelson Source Type: research