Anal human papillomavirus and its associations with abnormal anal cytology among men who have sex with men.
This study investigated anal HPV infections and cytological abnormalities among men who have sex with men (MSM). Sociodemographic characteristics and sexual behaviors were collected by using a structured questionnaire. Anal cytological results were examined, and HPV genotyping was performed by the Linear Array HPV Genotyping test. Logistic regression was used to estimate risk factors and their associations with high-risk HPV infection and cytological abnormalities. Among 163 MSM, 101 were seropositive for human immunodeficiency virus (HIV) and 62 were seronegative for HIV. The overall prevalence of HPV was 66.2%. A total o...
Source: Anal Sci - February 21, 2020 Category: Chemistry Authors: Wu PF, Hang JF, Strong C, Chen SJ, Lin LY, Chen SS, Lai CR, Ku SW, Lee MH Tags: Sci Rep Source Type: research

Soluble Tim3 detection by time-resolved fluorescence immunoassay and its application in membranous nephropathy.
Abstract BACKGROUND: We aimed to develop a time-resolved fluorescence immunoassay (TRFIA) for detecting soluble T-cell immunoglobulin and mucin domain 3 (sTim3) in serum samples and to demonstrate a preliminary application of this method in membranous nephropathy (MN). METHODS: sTim3 TRFIA was developed, and the sTim3 concentration in the serum of patients with MN and healthy individuals was detected using a sandwich method. RESULTS: The sensitivity of the developed sTim3 TRFIA was 0.66 ng/mL, higher than that of an enzyme-linked immunosorbent assay (ELISA) (1.11 ng/mL). The detection range was...
Source: Anal Sci - February 20, 2020 Category: Chemistry Authors: Chen M, Wang L, Wang Y, Zhou X, Liu X, Chen H, Huang B, Hu Z Tags: J Clin Lab Anal Source Type: research

A Failure to Communicate: Disentangling the Causes of Perianal Fistul æ in Crohn's Disease and Anal Squamous Cell Cancer.
A Failure to Communicate: Disentangling the Causes of Perianal Fistulæ in Crohn's Disease and Anal Squamous Cell Cancer. Dig Dis Sci. 2020 Feb 09;: Authors: Weingarden AR, Smith P, Streett S, Triadafilopoulos G PMID: 32037474 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - February 9, 2020 Category: Chemistry Authors: Weingarden AR, Smith P, Streett S, Triadafilopoulos G Tags: Dig Dis Sci Source Type: research

A multiplex PCR assay with a common primer for the  detection of eleven foodborne pathogens.
A multiplex PCR assay with a common primer for the detection of eleven foodborne pathogens. J Food Sci. 2020 Jan 30;: Authors: Tao J, Liu W, Ding W, Han R, Shen Q, Xia Y, Zhang Y, Sun W Abstract Salmonella enterica, Listeria monocytogenes, Shigella flexneri, Escherichia coli O157:H7, Vibrio parahaemolyticus, Staphylococcus aureus, Vibrio cholerae, Clostridium botulinum type A, Bacillus cereus, Clostridium perfringens Alpha toxin, and Yersinia enterocolitica are 11 common foodborne pathogens. Traditional bacterial culture methods for detecting pathogens are time-consuming and labor-intensive. Mult...
Source: Anal Sci - January 30, 2020 Category: Chemistry Authors: Tao J, Liu W, Ding W, Han R, Shen Q, Xia Y, Zhang Y, Sun W Tags: J Food Sci Source Type: research

A meta-analysis of the efficacy of HAART on HIV transmission and its impact on sexual risk behaviours among men who have sex with men.
te; Y Abstract Evidence showed preventive impacts of the highly active antiretroviral therapy (HAART) on the Human Immunodeficiency Virus (HIV) transmission amomg heterosexual population, however, that is of deficit among men who have sex with men (MSM). The aim was to systematically examine the efficacy of HAART on HIV transmission and the association between the HAART initiation and unprotected anal intercourse (UAI) in MSM population. Three electronic databases were fully searched for articles published in peer-reviewed journals between 1996 and 2017. Of 1616 identified articles, fifteen articles were eligible ...
Source: Anal Sci - January 23, 2020 Category: Chemistry Authors: Jiang Y, Su S, Borné Y Tags: Sci Rep Source Type: research

Effects of a single-bolus bupivacaine injection into the coccygeal spinal canal of rabbits.
Abstract It has been reported that drugs intended for epidural administration through the lumbosacral junction are accidentally administered into the subarachnoid space frequently in rabbits. Therefore, we evaluated the epidural single-bolus injection technique for the administration of bupivacaine into the coccygeal spinal canal of rabbits. After epidural distribution was confirmed by the injection of iohexol into the coccygeal spinal canal, 0.3 ml/kg 0.5% bupivacaine or 0.3 ml/kg normal saline was injected via the same needle. After the first attempt of iohexol injection, although the contrast was found in the e...
Source: Anal Sci - January 22, 2020 Category: Chemistry Authors: Ong BHE, Hidaka Y, Kaneko Y, Yamamoto S, Mizutani S, Sekiguchi S, Torisu S, Naganobu K Tags: J Vet Med Sci Source Type: research

Anal reflex versus bulbocavernosus reflex in evaluation of patients with spinal cord injury.
Abstract The examination of sacral reflexes provides an important method to differentiate an upper motor neuron vs lower motor neuron spinal cord injury (SCI). Two common sacral mediated reflexes used as part of the neurological assessment include the bulbocavernosus reflex (BCR) and anal reflex. As the clinical information from these tests are similar, we suggest that the anal reflex provides a better first option as a non-invasive clinical assessment of sacral reflex status in clinical practice in SCI as the testing for the anal reflex is less intrusive and already being performed as part of the International St...
Source: Anal Sci - January 16, 2020 Category: Chemistry Authors: Kirshblum S, Eren F Tags: Spinal Cord Ser Cases Source Type: research

The sacral exam-what is needed to best care for our patients?
Abstract Sacral reflexes are important to allow the SCI practitioner to gain information about the state of the sacral spinal cord segments. The presence of the bulbocavernosus and/or the anal wink reflex indicate an intact spinal reflex arc and reflex conal autonomic function (as part of the upper motor neuron syndrome); their absence defines a lower motor neuron syndrome. The assessment of sacral reflexes helps predict the type of bladder, bowel and sexual functions and the related therapeutic interventions. We suggest adding the sacral component of the International Standards for the Assessment of Autonomic Fun...
Source: Anal Sci - January 16, 2020 Category: Chemistry Authors: Previnaire JG, Alexander M Tags: Spinal Cord Ser Cases Source Type: research

Baseline and early 3D-CUBE volume reconstruction of locally advanced rectal cancer to predict tumor response after neoadjuvant chemotherapy.
Abstract PURPOSE: To explore whether volumetric measurements of 3D-CUBE sequences based on baseline and early treatment time can predict neoadjuvent chemotherapy (NCT) efficacy of locally advanced rectal cancer (LARC). MATERIAL AND METHOD: 73 patients with LARC were enrolled from February 2014 to January 2018. All patients underwent MRIs during the baseline period before NCT (BL-NCT) and the first month of NCT (FM-NCT), and tumor volume (TV) was measured using 3D-CUBE, and tumor volume reduction (TVR) and tumor volume reduction rate (TVRR) were calculated. In addition, tumor invasion depth, tumor maximal leng...
Source: Anal Sci - January 6, 2020 Category: Chemistry Authors: Wang XH, Liu ZJ, Xu JB, Li FQ, Li WL, Cao WT, Zhou ZY Tags: J Xray Sci Technol Source Type: research

Various significant connections of the male pelvic floor muscles with special reference to the anal and urethral sphincter muscles.
In this study, we examined the male pelvic floor to clarify the connection between the muscles related to function. Fifteen male pelvises were used for microscopic dissection, and three male pelvises were used for histological examination. On the lateral aspect, the perineal muscles were connected to each other. Bundles of the levator ani muscle extended to connect to the perineal muscles. In addition, the extended muscle bundle from the levator ani muscle and the perineal muscles surround the external urethral sphincter. On the medial aspect, the levator ani muscle and the external anal sphincter form the anterior and pos...
Source: Anal Sci - December 23, 2019 Category: Chemistry Authors: Suriyut J, Muro S, Baramee P, Harada M, Akita K Tags: Anat Sci Int Source Type: research

Loganin alleviates LPS-activated intestinal epithelial inflammation by regulating TLR4/NF- κB and JAK/STAT3 signaling pathways.
In conclusion, loganin inhibited LPS-activated intestinal epithelial inflammation by repressing TLR4/NF-κB and JAK/STAT3 signaling pathway. PMID: 31859422 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - December 20, 2019 Category: Chemistry Authors: Wang JW, Pan YB, Cao YQ, Wang C, Jiang WD, Zhai WF, Lu JG Tags: Kaohsiung J Med Sci Source Type: research

Quantitative Analysis of Red Phosphorus in Polypropylene by Evolved Gas Analysis Mass Spectrometry.
PMID: 31839661 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - December 13, 2019 Category: Chemistry Authors: Ishimura T, Watanabe A, Watanabe C, Teramae N Tags: Anal Sci Source Type: research

Simplified mercury extraction from coal fly ash for quantification of total mercury by ELISA-based immunoassay.
PMID: 31839662 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - December 13, 2019 Category: Chemistry Authors: Date Y, Masaki H, Aota A, Sasaki K, Namiki Y, Glass TR, Ohmura N Tags: Anal Sci Source Type: research

A fluorescent sensor based on RAFT polymerization for the early diagnosis of non-small cell lung cancer.
PMID: 31839663 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - December 13, 2019 Category: Chemistry Authors: Liu W, Ma L, Guo Z, Liu T, Liu Y, Wang D, Kong J Tags: Anal Sci Source Type: research

Analyze of oxadiazon herbicide in natural waters by a micellar-enhanced photo-induced fluorescence.
PMID: 31839664 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - December 13, 2019 Category: Chemistry Authors: Bakhoum JP, Mbaye OMA, Diaw PA, Cisse L, Mbaye M, Gaye-Seye MD, Coly A, LE Jeune B, Giamarchi P Tags: Anal Sci Source Type: research

Development of Aedes aegypti (Diptera: Culicidae) mosquito larvae in high ammonia sewage in septic tanks causes alterations in ammonia excretion, ammonia transporter expression, and osmoregulation.
Abstract Larvae of the disease vector mosquito, Aedes aegypti (L.) readily develop in ammonia rich sewage in the British Virgin Islands. To understand how the larvae survive in ammonia levels that are lethal to most animals, an examination of ammonia excretory physiology in larvae collected from septic-water and freshwater was carried out. A. aegypti larvae were found to be remarkably plastic in dealing with high external ammonia through the modulation of NH4+ excretion at the anal papillae, measured using the scanning ion-selective electrode technique (SIET), and NH4+ secretion in the primary urine by the Malpigh...
Source: Anal Sci - December 13, 2019 Category: Chemistry Authors: Durant AC, Donini A Tags: Sci Rep Source Type: research

Analysis of the Dissipation Behavior of Defoliants in Cotton Fiber during Field and Scouring Process Using Liquid and Gas Chromatography.
This study was carried out to evaluate the dissipation behavior of four commonly used defoliants tribufos, diuron, thidiazuron, and ethephon in cotton fiber during field stage and also in cotton scouring using liquid chromatography and gas chromatography. Field trials showed that although all the defoliants dissipated fast, however, the fiber from the tribufos and ethephon applied field had considerable potential to exceed the maximum residue limit when the fiber was harvested at common intervals after application of defoliants. The defoliant residues could be removed completely from the defoliant-carrying cotton textiles ...
Source: Anal Sci - December 11, 2019 Category: Chemistry Authors: Ma M, Ayaz P, Jin W, Hussain M, Zhou W Tags: Int J Anal Chem Source Type: research

BioSphincters to treat Fecal Incontinence in Nonhuman Primates.
Abstract Loss of anorectal resting pressure due to internal anal sphincter (IAS) dysfunctionality causes uncontrolled fecal soiling and leads to passive fecal incontinence (FI). The study is focused on immediate and long-term safety and potential efficacy of bioengineered IAS BioSphincters to treat passive FI in a clinically relevant large animal model of passive FI. Passive FI was successfully developed in Non-Human Primates (NHPs) model. The implantation of autologous intrinsically innervated functional constructs resolved the fecal soiling, restored the resting pressure and Recto Anal Inhibitory Reflex (RAIR) w...
Source: Anal Sci - December 2, 2019 Category: Chemistry Authors: Dadhich P, Bohl JL, Tamburrini R, Zakhem E, Scott C, Kock N, Mitchell E, Gilliam J, Bitar KN Tags: Sci Rep Source Type: research

The role of magnetic resonance imaging in the preoperative evaluation of anal fistulas.
In conclusion, MRI can be considered an accurate tool for the preoperative evaluation of fistula-in-ano, which is a major determinant of the surgical outcome. Both T2W TSE and post-contrast FS T1W TSE sequences are highly accurate in depicting the features of fistula-in-ano. If there are no contraindications, contrast administration is recommended to differentiate abscesses from active inflammation. PMID: 31784600 [PubMed - in process] (Source: Anal Sci)
Source: Anal Sci - November 29, 2019 Category: Chemistry Authors: Vo D, Phan C, Nguyen L, Le H, Nguyen T, Pham H Tags: Sci Rep Source Type: research

The variation degree of coagulation function is not responsible for extra risk of hemorrhage in gestational diabetes mellitus.
CONCLUSIONS: The GDM group was hypercoagulable compared with the NGT group rather than hypocoagulable as predicted, but still within the normal range. Therefore, our findings demonstrate that the variation degree of coagulation function is not responsible for extra risk of hemorrhage in GDM, and prevention of hemorrhage should focus on other causes. PMID: 31774215 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - November 27, 2019 Category: Chemistry Authors: Dong C, Gu X, Chen F, Long Y, Zhu D, Yang X, Qiu X, Gao G, Qi W Tags: J Clin Lab Anal Source Type: research

Comparison of Familial Clustering of Anogenital and Skin Cancers Between In Situ and Invasive Types.
i K Abstract Literature on familial risk of carcinomas in situ (CISs) is limited because many cancer registries do not collect information on CIS. In Sweden CISs are collected, and we used these data to analyze familial relative risks (RRs) for concordant (CIS-CIS) types of anogenital (cervical, other female and male genital and anal) and skin squamous cell CIS; additionally RRs were assessed between CIS types and between CIS and invasive forms. RRs were calculated for the offspring generations when family members were diagnosed CIS. Case numbers for CIS ranged from 330 in anal to 177,285 in cervical CIS. Signific...
Source: Anal Sci - November 6, 2019 Category: Chemistry Authors: Zhang L, Hemminki O, Zheng G, Försti A, Sundquist K, Sundquist J, Hemminki K Tags: Sci Rep Source Type: research

Diagnosing uncertainty: The challenges of implementing medical screening programs for minority sub-populations in Canada.
Abstract The social science literature on medical screening has documented a notable disjuncture between the promises of population-based screening programs and the complex realities of their rollout in everyday practice. We contribute to this scholarship by examining how healthcare providers confront numerous uncertainties associated with the implementation of anal cancer screening programs in Canada given the absence of standardized national evidence-based guidelines. The data was derived from in-depth interviews conducted with 13 physicians and 2 clinical researchers about anal cancer screening for gay, bisexua...
Source: Anal Sci - October 28, 2019 Category: Chemistry Authors: Gaspar M, Rosenes R, Burchell AN, Grennan T, Salit I, Grace D Tags: Soc Sci Med Source Type: research

A one-year longitudinal study of enterohemorrhagic Escherichia coli O157 fecal shedding in a beef cattle herd.
PJ, Fort MC Abstract Bovines are the primary reservoir of enterohemorrhagic Escherichia coli (EHEC) O157:H7 and the main source of its transmission to humans. Here, we present a one-year longitudinal study of fecal shedding of E. coli O157. E. coli O157 obtained from recto-anal mucosal samples were characterized by multiplex PCR. The E. coli O157 prevalence ranged from 0.84% in July to 15.25% in November. The confinement within pens resulted in prevalence of 11%. Most animals (61.86%; 75/118) shed E. coli O157 at least in one sampling occasion. Of the positive animals, 82.19%, 16.44%, and 1.37% were stx positive o...
Source: Anal Sci - October 16, 2019 Category: Chemistry Authors: Rhades LC, Larzábal M, Bentancor A, García JSY, Babinec FJ, Cataldi A, Amigo N, Baldone VN, Urquiza L, Delicia PJ, Fort MC Tags: Res Vet Sci Source Type: research

Anti-Colorectal Cancer Mechanisms of Formononetin Identified by Network Pharmacological Approach.
CONCLUSIONS The anti-CRC molecular mechanisms of FN are implicated in suppression of cellular proliferation and regulation of cancer-related metabolic pathways. Interestingly, 8 optimal biological targets may be used as potential molecular markers for predicting and treating CRC. PMID: 31608899 [PubMed - in process] (Source: Anal Sci)
Source: Anal Sci - October 14, 2019 Category: Chemistry Authors: Zhang L, Gong Y, Wang S, Gao F Tags: Med Sci Monit Source Type: research

Selection Technologies and Applications of Nucleic Acid Aptamers.
Abstract PMID: 31597871 [PubMed - in process] (Source: Anal Sci)
Source: Anal Sci - October 11, 2019 Category: Chemistry Authors: Yoshimoto K Tags: Anal Sci Source Type: research

Dynamic Measurement Method for Bio-molecular Interactions by Using Centrifugal Force.
Abstract Measurement of single molecule interaction is performed by various micromanipulation techniques. However, a complex operation is required to perform the measurement, so the measurement throughput is low and a large amount of time is required for statistical analysis. In this paper, we propose a method for measuring intermolecular interactions that applies a tensile force to the intermolecular bond by using centrifugal force and can easily measure binding force. The binding force of an antigen-antibody reaction system was measured by the use of the proposed method as a proof of concept. The measured bindin...
Source: Anal Sci - October 11, 2019 Category: Chemistry Authors: Otake M, Ukita Y Tags: Anal Sci Source Type: research

A Microfluidic Platform Based on Robust Gas and Liquid Exchange for Long-term Culturing of Explanted Tissues.
Abstract Microfluidic devices are important platforms to culture and observe biological tissues. Compared with conventional setups, microfluidic devices have advantages in perfusion, including an enhanced delivery of nutrients and gases to tissues. However, explanted tissues can maintain their functions for only hours to days in microfluidic devices, although their observations are desired for weeks. The suprachiasmatic nucleus (SCN) is a brain region composed of heterogeneous cells to control the biological clock system through synchronizing individual cells in this region. The synchronized and complicated cell-c...
Source: Anal Sci - October 11, 2019 Category: Chemistry Authors: Ota N, Kanda GN, Moriguchi H, Aishan Y, Shen Y, Yamada RG, Ueda HR, Tanaka Y Tags: Anal Sci Source Type: research

Serum C-Reactive Protein and Max Polyp Diameter Are Useful Markers of Complications of Small-Intestinal Polypectomy.
CONCLUSIONS SBE is an effective endoscopic tool for patients with small-intestinal polyps. CRP, Dmax, and the combination of CRP+Dmax may be potential predictors of complications from small-intestinal polypectomy. PMID: 31582716 [PubMed - in process] (Source: Anal Sci)
Source: Anal Sci - October 4, 2019 Category: Chemistry Authors: Tu J, Gao H, Pan W Tags: Med Sci Monit Source Type: research

Ipsilateral S2 nerve root transfer to pudendal nerve for restoration of external anal and urethral sphincter function: an anatomical study.
Abstract Patients suffer bilateral sacral plexus injuries experience severe problems with incontinence. We performed a cadaveric study to explore the anatomical feasibility of transferring ipsilateral S2 nerve root combined with a sural nerve graft to pudendal nerve for restoration of external anal and urethral sphincter function. The sacral nerve roots and pudendal nerve roots on the right side were exposed in 10 cadavers. The length from S2 nerve root origin to pudendal nerve at inferior border of piriformis was measured. The sural nerve was used as nerve graft. The diameters and nerve cross-sectional areas of S...
Source: Anal Sci - September 30, 2019 Category: Chemistry Authors: Zhu L, Zhou ZB, Shen D, Chen AM Tags: Sci Rep Source Type: research

Association between nucleotide excision repair gene polymorphism and colorectal cancer risk.
CONCLUSION: In brief, our finding demonstrated that ERCC4 rs6498486 serves as a potential biomarker of CRC susceptibility for the development of colorectal cancer. PMID: 31568607 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - September 30, 2019 Category: Chemistry Authors: Zhang Y, Wu S, Zhou X, Huang F, Chen R, Wang Y, Wu J Tags: J Clin Lab Anal Source Type: research

Ultrasonic Piezoelectric Nebulization of Propoxur for the Determination by Corona Discharge Ionization Ion Mobility Spectrometry.
PMID: 31564676 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - September 27, 2019 Category: Chemistry Authors: Tabibi A, Jafari MT Tags: Anal Sci Source Type: research

Fluorescence quenching of the probes L-Tryptophan and Indole by anions in aqueous system.
PMID: 31564677 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - September 27, 2019 Category: Chemistry Authors: Idrees M, Ayaz M, Bibi R, Khan MN Tags: Anal Sci Source Type: research

Effects of Diluents on the Separation of Minor Actinides from Lanthanides with Tetradodecyl-1,10-Phenanthroline-2,9-Diamide (TDdPTDA) from Nitric Acid Medium.
PMID: 31564678 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - September 27, 2019 Category: Chemistry Authors: Tsutsui N, Ban Y, Suzuki H, Nakase M, Ito S, Inaba Y, Matsumura T, Takeshita K Tags: Anal Sci Source Type: research

Evaluation of Calibration Method for Accurate Analysis of Dissolved Silica by Continuous Flow Analysis.
PMID: 31564679 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - September 27, 2019 Category: Chemistry Authors: Cheong C, Sakaguchi A, Sueki K, Ohata M Tags: Anal Sci Source Type: research

Separation and Pre-concentration of Trace Uranium (VI) by Solid Phase Extraction with 2,3-Dihydroxynaphthalene and Cetyltrimethylammoniumbromide on Molten Naphthalene and its LED Fluorimetric Determination in Water Samples.
PMID: 31527316 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - September 13, 2019 Category: Chemistry Authors: Pradhan SK, Ambade B Tags: Anal Sci Source Type: research

Optimization of total polar compounds quantification in frying oils by low-field nuclear magnetic resonance.
PMID: 31527317 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - September 13, 2019 Category: Chemistry Authors: Zhou X, Chen Y, Yang Q, Liu Y, Wu Y, Lu R, Ni Z Tags: Anal Sci Source Type: research

Fabrication of a Phosphate Ion Selective Electrode Based on Modified Molybdenum Metal.
PMID: 31527318 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - September 13, 2019 Category: Chemistry Authors: Xu K, Kitazumi Y, Kano K, Sasaki T, Shirai O Tags: Anal Sci Source Type: research

Immunomodulatory Nanosystems.
Abstract Immunotherapy has emerged as an effective strategy for the prevention and treatment of a variety of diseases, including cancer, infectious diseases, inflammatory diseases, and autoimmune diseases. Immunomodulatory nanosystems can readily improve the therapeutic effects and simultaneously overcome many obstacles facing the treatment method, such as inadequate immune stimulation, off-target side effects, and bioactivity loss of immune agents during circulation. In recent years, researchers have continuously developed nanomaterials with new structures, properties, and functions. This Review provides the most...
Source: Anal Sci - September 4, 2019 Category: Chemistry Authors: Feng X, Xu W, Li Z, Song W, Ding J, Chen X Tags: Adv Sci (Weinh) Source Type: research

Using Smartphone Survey Data and Machine Learning to Identify Situational and Contextual Risk Factors for HIV Risk Behavior Among Men Who Have Sex with Men Who Are Not on PrEP.
ti PM Abstract "Just-in-time" interventions (JITs) delivered via smartphones have considerable potential for reducing HIV risk behavior by providing pivotal support at key times prior to sex. However, these programs depend on a thorough understanding of when risk behavior is likely to occur to inform the timing of JITs. It is also critical to understand the most important momentary risk factors that may precede HIV risk behavior, so that interventions can be designed to address them. Applying machine learning (ML) methods to ecological momentary assessment data on HIV risk behaviors can help answer both ...
Source: Anal Sci - May 9, 2019 Category: Chemistry Authors: Wray TB, Luo X, Ke J, Pérez AE, Carr DJ, Monti PM Tags: Prev Sci Source Type: research

Non-invasive obstetric anal sphincter injury diagnostics using impedance spectroscopy.
Abstract Obstetric anal sphincter injuries are the most common cause of fecal incontinence in women yet remain under-diagnosed. The aim of this study was to assess the suitability of impedance spectroscopy for diagnosing sphincter injuries arising during delivery. This was a prospective single-center study. 22 female patients were included: 10 with symptoms of sphincter dysfunction, in the early postpartum period, and 12 unaffected, in the distant period of more than 2 years after natural delivery. The presence, extent and severity of anal sphincters injury was assessed by measuring the sphincter parameters in phy...
Source: Anal Sci - May 8, 2019 Category: Chemistry Authors: Borycka-Kiciak K, Młyńczak M, Kiciak A, Pietrzak P, Dziki A Tags: Sci Rep Source Type: research

Downregulation of thromboxane A2 and angiotensin II type 1 receptors associated with aging-related decrease in internal anal sphincter tone.
Abstract Aging-associated decrease in internal anal sphincter (IAS) tone (AADI) is a major contributor in the rectoanal incontinence (RI). To determine the pathogenesis of AADI, we investigated the effect of aging on GPCR activation and related downstream signaling. We particularly investigated two GPCRs that characterize IAS smooth muscle cells (SMCs): thromboxane A2 and angiotensin II type 1. Two groups of Fischer 344 rats (6-month-old [young group] and 26-month-old [old group]) were employed to determine the GPCR function by isometric contraction, the expressions of GPCRs, and their downstream regulatory signal...
Source: Anal Sci - May 1, 2019 Category: Chemistry Authors: Mohanty I, Singh J, Rattan S Tags: Sci Rep Source Type: research

Comparative pharmacokinetic study on phenolic acids and flavonoids in spinal cord injury rats plasma by UPLC-MS/MS after single and combined oral administration of danshen and huangqin extract.
Abstract Chinese medicinal herbs danshen and huangqin have attracted attention in spinal cord injury (SCI) treatment. Purpose of this study was to investigate and compare the pharmacokinetic characteristics of 4 phenolic acids and 4 flavonoids in SCI rat plasma after orally administrate danshen, huangqin and combined extract of these two herbs (CDH). Thus, a rapid and sensitive ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for simultaneously quantitative determination of tanshinol, protocatechualdehyde, protocatechuic acid, salvianolic acid A, baic...
Source: Anal Sci - April 20, 2019 Category: Chemistry Authors: Zhang L, Liu X, Yang H, Zhao R, Liu C, Zhang R, Zhang Q Tags: J Pharm Biomed Anal Source Type: research

A Bayesian approach for semiparametric regression analysis of panel count data.
Abstract Panel count data commonly arise in epidemiological, social science, and medical studies, in which subjects have repeated measurements on the recurrent events of interest at different observation times. Since the subjects are not under continuous monitoring, the exact times of those recurrent events are not observed but the counts of such events within the adjacent observation times are known. A Bayesian semiparametric approach is proposed for analyzing panel count data under the proportional mean model. Specifically, a nonhomogeneous Poisson process is assumed to model the panel count response over time, ...
Source: Anal Sci - April 15, 2019 Category: Chemistry Authors: Wang J, Lin X Tags: Lifetime Data Anal Source Type: research

Restriction of dietary non-phytate phosphorus on growth performance and expression of intestinal phosphate cotransporter genes in broilers.
Abstract Effects of dietary non-phytate phosphorus (nPP) restriction on growth and duodenal type IIb sodium-dependent phosphate cotransporter (NaPi-IIb) genes were observed. A total of 432 one-day old Cobb500 male broiler chickens in 36 cage pens were divided into 6 groups with each group containing 6 pens. Each group was treated with one of the diets containing 0.33, 0.37, 0.41, 0.45, 0.49, and 0.53% of nPP up to 14 D. During 15 to 31 D, birds were treated with one of the diets containing 0.23, 0.27, 0.31, 0.35, 0.39, and 0.43% of nPP. Level of Ca was kept the same across all treatments. Dietary nPP level influenced (P
Source: Anal Sci - April 13, 2019 Category: Chemistry Authors: Tay-Zar AC, Srichana P, Sadiq MB, Anal AK Tags: Poult Sci Source Type: research

Patient satisfaction with a multidisciplinary colorectal and urogynaecology service.
CONCLUSION: There is a high level of satisfaction amongst women attending our outpatient service. Being seen by multiple specialities at a single clinic was felt to be of benefit by the majority of women and all expressed physician confidence. Our multidisciplinary service may reduce waiting times, increase satisfaction, and is likely cost-effective. PMID: 30945112 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - April 3, 2019 Category: Chemistry Authors: O'Leary BD, Agnew GJ, Fitzpatrick M, Hanly AM Tags: Ir J Med Sci Source Type: research

Fabrication of polydimethylsiloxane (PDMS) fluidic chip using sacrificial template made by fused deposition modeling (FDM) 3D printing and application for flow injection analysis.
PMID: 30905901 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - March 22, 2019 Category: Chemistry Authors: Yamashita T, Yasukawa K, Yunoki E Tags: Anal Sci Source Type: research

Determination of Water Content of Nitrogen Containing Hydrogen Sulfide by Karl Fischer Coulometric Titration.
PMID: 30905902 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - March 22, 2019 Category: Chemistry Authors: Zhi X, Wang H, Liu B, Song X, Li Z, Li J Tags: Anal Sci Source Type: research

Development of Tube Radial Distribution Chromatography Based on Phase-Separation Multiphase Flow Created via Pressure Loss.
PMID: 30905903 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - March 22, 2019 Category: Chemistry Authors: Wada S, Tsukagoshi K, Tsuchiya K, Hirota K, Yamashita K, Murata M Tags: Anal Sci Source Type: research

Purge-and-trap Determination of Ammonia in Water Samples Using Needle-Type Extraction Coupled with Gas Chromatography-Barrier Discharge Ionization Detection.
PMID: 30905904 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - March 22, 2019 Category: Chemistry Authors: Ueta I, Fujikawa H, Fujimura K, Saito Y Tags: Anal Sci Source Type: research

Evaluation of Surface Structure of Escherichia coli Using Polypyrrole Matrix.
PMID: 30905905 [PubMed - as supplied by publisher] (Source: Anal Sci)
Source: Anal Sci - March 22, 2019 Category: Chemistry Authors: Nguyen DQ, Shan X, Saito M, Iwamoto K, Chen Z, Shiigi H Tags: Anal Sci Source Type: research