Recent advances in the development of < sup > 225 < /sup > Ac- and < sup > 211 < /sup > At-labeled radioligands for radiotheranostics
Anal Sci. 2024 Apr 2. doi: 10.1007/s44211-024-00514-w. Online ahead of print.ABSTRACTRadiotheranostics utilizes a set of radioligands incorporating diagnostic or therapeutic radionuclides to achieve both diagnosis and therapy. Imaging probes using diagnostic radionuclides have been used for systemic cancer imaging. Integration of therapeutic radionuclides into the imaging probes serves as potent agents for radionuclide therapy. Among them, targeted alpha therapy (TAT) is a promising next-generation cancer therapy. The α-particles emitted by the radioligands used in TAT result in a high linear energy transfer over a short ...
Source: Anal Sci - April 2, 2024 Category: Chemistry Authors: Masayuki Munekane Takeshi Fuchigami Kazuma Ogawa Source Type: research
Novel analytical technologies contributing to clinical and pharmaceutical research fields
Anal Sci. 2024 Apr 2. doi: 10.1007/s44211-024-00558-y. Online ahead of print.NO ABSTRACTPMID:38564088 | DOI:10.1007/s44211-024-00558-y (Source: Anal Sci)
Source: Anal Sci - April 2, 2024 Category: Chemistry Authors: Shigeori Takenaka Shinobu Sato Kenji Hamase Tadashi Hayama Source Type: research
Recent advances in the development of < sup > 225 < /sup > Ac- and < sup > 211 < /sup > At-labeled radioligands for radiotheranostics
Anal Sci. 2024 Apr 2. doi: 10.1007/s44211-024-00514-w. Online ahead of print.ABSTRACTRadiotheranostics utilizes a set of radioligands incorporating diagnostic or therapeutic radionuclides to achieve both diagnosis and therapy. Imaging probes using diagnostic radionuclides have been used for systemic cancer imaging. Integration of therapeutic radionuclides into the imaging probes serves as potent agents for radionuclide therapy. Among them, targeted alpha therapy (TAT) is a promising next-generation cancer therapy. The α-particles emitted by the radioligands used in TAT result in a high linear energy transfer over a short ...
Source: Anal Sci - April 2, 2024 Category: Chemistry Authors: Masayuki Munekane Takeshi Fuchigami Kazuma Ogawa Source Type: research
Novel analytical technologies contributing to clinical and pharmaceutical research fields
Anal Sci. 2024 Apr 2. doi: 10.1007/s44211-024-00558-y. Online ahead of print.NO ABSTRACTPMID:38564088 | DOI:10.1007/s44211-024-00558-y (Source: Anal Sci)
Source: Anal Sci - April 2, 2024 Category: Chemistry Authors: Shigeori Takenaka Shinobu Sato Kenji Hamase Tadashi Hayama Source Type: research
Anthraquinone/activated carbon electrochemical sensor and its application in acetaminophen analysis
Anal Sci. 2024 Apr 1. doi: 10.1007/s44211-024-00537-3. Online ahead of print.ABSTRACTAcetaminophen (AC) can inhibit the synthesis of prostaglandins in the body, and has antipyretic and analgesic effects. In this paper, a two-step microwave impregnation method was used to prepare anthraquinone (AQ)-doped carbon composite, which were applied to the surface modification of glassy carbon electrodes (GCE) for the determination of acetaminophen (AC) using differential pulse voltammetry (DPV). The composites were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), Raman and Fourier infrared spectroscopy ...
Source: Anal Sci - April 1, 2024 Category: Chemistry Authors: Cailing Zhong Yuwen Chen Yixuan Zheng Qifeng Tian Yichang Chen Mingjiang Xie Zhengfang Tian Source Type: research
Risk of Secondary Malignancies After Pelvic Radiation: A Population-based Analysis
CONCLUSIONS AND CLINICAL IMPLICATIONS: Except for localized cervical cancer, when put in the context of median overall survival, the impact of radiation likely does not carry enough weight to change practice patterns. Radiation for pelvic malignancies increases the risk for several secondary malignancies, and more specifically, secondary pelvic malignancies, but with a relatively low absolute risk of secondary malignancies, the benefits of radiation warrant continued use for most pelvic malignancies. Practice changes should be considered for radiation utilization in malignancies with excellent cancer-specific survival such...
Source: Anal Sci - April 1, 2024 Category: Chemistry Authors: Connor McPartland Andrew Salib Joshua Banks James R Mark Costas D Lallas Edouard J Trabulsi Leonard G Gomella Hanan Goldberg Benjamin Leiby Robert Den Thenappan Chandrasekar Source Type: research
Anthraquinone/activated carbon electrochemical sensor and its application in acetaminophen analysis
Anal Sci. 2024 Apr 1. doi: 10.1007/s44211-024-00537-3. Online ahead of print.ABSTRACTAcetaminophen (AC) can inhibit the synthesis of prostaglandins in the body, and has antipyretic and analgesic effects. In this paper, a two-step microwave impregnation method was used to prepare anthraquinone (AQ)-doped carbon composite, which were applied to the surface modification of glassy carbon electrodes (GCE) for the determination of acetaminophen (AC) using differential pulse voltammetry (DPV). The composites were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), Raman and Fourier infrared spectroscopy ...
Source: Anal Sci - April 1, 2024 Category: Chemistry Authors: Cailing Zhong Yuwen Chen Yixuan Zheng Qifeng Tian Yichang Chen Mingjiang Xie Zhengfang Tian Source Type: research
Risk of Secondary Malignancies After Pelvic Radiation: A Population-based Analysis
CONCLUSIONS AND CLINICAL IMPLICATIONS: Except for localized cervical cancer, when put in the context of median overall survival, the impact of radiation likely does not carry enough weight to change practice patterns. Radiation for pelvic malignancies increases the risk for several secondary malignancies, and more specifically, secondary pelvic malignancies, but with a relatively low absolute risk of secondary malignancies, the benefits of radiation warrant continued use for most pelvic malignancies. Practice changes should be considered for radiation utilization in malignancies with excellent cancer-specific survival such...
Source: Anal Sci - April 1, 2024 Category: Chemistry Authors: Connor McPartland Andrew Salib Joshua Banks James R Mark Costas D Lallas Edouard J Trabulsi Leonard G Gomella Hanan Goldberg Benjamin Leiby Robert Den Thenappan Chandrasekar Source Type: research
Unveiling the vitamin E profile in rice bran extracellular vesicles: evaluation of extraction and preparation methods
This study is the first to identify tocopherol and tocotrienol in rice bran-derived EVs. Our results indicate that ultracentrifugation followed by rotation is the most effective method for the preparation of rice bran-derived EVs. Notably, the vitamin E profile in EVs varies depending on the preparation method and differs from that in rice bran extracts. The pronounced presence of vitamin E in EVs suggests unique pharmacokinetics and underscores the potential of EVs as carriers for drug delivery systems. This study not only confirms the presence of vitamin E in EVs, but also underscores the potential of EVs and their phyto...
Source: Anal Sci - March 31, 2024 Category: Chemistry Authors: Soo Takasu Risa Watanabe Nobuhiko Sugito Kohei Morikawa Akio Iio Yukihiro Esaka Yukihiro Akao Source Type: research
Design of cobalt-doped graphene quantum dot-decorated vanadium pentoxide nanosheet-based Off-On fluorescent sensor system for tiopronin sensing
Anal Sci. 2024 Mar 30. doi: 10.1007/s44211-024-00548-0. Online ahead of print.ABSTRACTDespite the high medicinal value of tiopronin, there are substantial adverse effects such as yellow skin, yellow eyes, muscle aches, etc. Therefore, there is a huge necessity to identify tiopronin using advanced sensors in provided samples. Recently, the preference for graphene quantum dots (GQDs) and inorganic nanomaterial-based fluorescent sensors for the detection of pharmaceuticals has been extensively documented due to their plentiful advantages. Therefore, in this work, the cobalt-doped GQDs decorated vanadium pentoxide nanosheet-ba...
Source: Anal Sci - March 30, 2024 Category: Chemistry Authors: Sopan Nangare Kajal Kolte Zamir Khan Ashwini Patil Namdeo Jadhav Sai H S Boddu Manoj Charde Pravin Patil Source Type: research
Design of cobalt-doped graphene quantum dot-decorated vanadium pentoxide nanosheet-based Off-On fluorescent sensor system for tiopronin sensing
Anal Sci. 2024 Mar 30. doi: 10.1007/s44211-024-00548-0. Online ahead of print.ABSTRACTDespite the high medicinal value of tiopronin, there are substantial adverse effects such as yellow skin, yellow eyes, muscle aches, etc. Therefore, there is a huge necessity to identify tiopronin using advanced sensors in provided samples. Recently, the preference for graphene quantum dots (GQDs) and inorganic nanomaterial-based fluorescent sensors for the detection of pharmaceuticals has been extensively documented due to their plentiful advantages. Therefore, in this work, the cobalt-doped GQDs decorated vanadium pentoxide nanosheet-ba...
Source: Anal Sci - March 30, 2024 Category: Chemistry Authors: Sopan Nangare Kajal Kolte Zamir Khan Ashwini Patil Namdeo Jadhav Sai H S Boddu Manoj Charde Pravin Patil Source Type: research
Optimum management for complex anal fistula: A network meta-analysis of randomized controlled trials
CONCLUSION: The combination of LIFT with plug or PRP resulted in lower failure and complication rates in the management of complex anal fistula compared to the other methods tested.PMID:38550268 | PMC:PMC10973174 | DOI:10.1016/j.sopen.2024.03.003 (Source: Anal Sci)
Source: Anal Sci - March 29, 2024 Category: Chemistry Authors: None Warsinggih Citra Aryanti Muhammad Faruk Source Type: research
Isolation and genomic characterization of chicken infectious anemia virus in Jiangsu province of China during 2020-2022
In this study, a total of 223 clinical samples, including anal swabs, tissues, blood, and vaccines, were collected from 19 broiler farms or breeding companies in Jiangsu province, with symptoms of significant anemia and immunosuppression during 2020-2022. Among them, 75 samples (75/223, 33.6%) were positive for CIAV in polymerase chain reaction (PCR) test, and 20 CIAV strains were successfully isolated. The phylogenetic trees of the 20 isolates and 42 CIAV strains deposited in GenBank formed four distinct groups (A-D). And the isolates mainly belonged to Group A but with high genetic diversity. Analysis for VP1 indicated t...
Source: Anal Sci - March 29, 2024 Category: Chemistry Authors: Jun Zhang Li Ma Tuofan Li Quan Xie Zhimin Wan Aijian Qin Jianqiang Ye Hongxia Shao Shengnan Wang Source Type: research
Optimum management for complex anal fistula: A network meta-analysis of randomized controlled trials
CONCLUSION: The combination of LIFT with plug or PRP resulted in lower failure and complication rates in the management of complex anal fistula compared to the other methods tested.PMID:38550268 | PMC:PMC10973174 | DOI:10.1016/j.sopen.2024.03.003 (Source: Anal Sci)
Source: Anal Sci - March 29, 2024 Category: Chemistry Authors: None Warsinggih Citra Aryanti Muhammad Faruk Source Type: research
Isolation and genomic characterization of chicken infectious anemia virus in Jiangsu province of China during 2020-2022
In this study, a total of 223 clinical samples, including anal swabs, tissues, blood, and vaccines, were collected from 19 broiler farms or breeding companies in Jiangsu province, with symptoms of significant anemia and immunosuppression during 2020-2022. Among them, 75 samples (75/223, 33.6%) were positive for CIAV in polymerase chain reaction (PCR) test, and 20 CIAV strains were successfully isolated. The phylogenetic trees of the 20 isolates and 42 CIAV strains deposited in GenBank formed four distinct groups (A-D). And the isolates mainly belonged to Group A but with high genetic diversity. Analysis for VP1 indicated t...
Source: Anal Sci - March 29, 2024 Category: Chemistry Authors: Jun Zhang Li Ma Tuofan Li Quan Xie Zhimin Wan Aijian Qin Jianqiang Ye Hongxia Shao Shengnan Wang Source Type: research
