Blood Pressure Regulation and Hypertension in Obstructive Sleep Apnea Syndrome: A Historical Perspective
Intern Med. 2024 Apr 16. doi: 10.2169/internalmedicine.2960-23. Online ahead of print.ABSTRACTIn obstructive sleep apnea syndrome (OSAS), an underlying disease of secondary hypertension, repeated episodes of asphyxia due to obstructive sleep apnea (OSA), followed by arousal, lead to various cardiovascular consequences. Using a canine model of OSAS, it was found that a single load of OSA caused an abrupt increase in blood pressure (BP) (Apnea Surge in seconds), while multiple OSA episodes occurring nightly for 1-3 months led to a sustained elevation of BP during both nighttime and daytime. Epidemiological studies on 24-hour...
Source: Internal Medicine - April 17, 2024 Category: Internal Medicine Authors: Fumihiko Yasuma Akiko Noda Junichiro Hayano Source Type: research
Once upon a time in Anatolia: the kings with bulging eyes
Hormones (Athens). 2024 Apr 18. doi: 10.1007/s42000-024-00561-y. Online ahead of print.ABSTRACTThe Hittite Empire, formed by the Hittites who settled in central Anatolia at the beginning of the second millennium BC, has left behind rich archeological remains. In this historical review, statues of the Hittite priest-kings, King Idrimi, King Šuppiluliuma, and King Tarhunza, who ruled in these lands in ancient times, are analyzed. Graves' disease (GD) is the most common cause of hyperthyroidism. Patients with GD are also at risk of developing Graves' orbitopathy (GO). Upper eyelid retraction and exophthalmos (bulging eyes) a...
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Hulya Elbe Source Type: research
Case series of retinal vein occlusions showing early recovery using oral l-methylfolate
Ther Adv Ophthalmol. 2024 Apr 15;16:25158414241240687. doi: 10.1177/25158414241240687. eCollection 2024 Jan-Dec.ABSTRACTThis case series describes the aggregate rate of recovery in five consecutive subjects (six eyes) with retinal vein occlusion (RVO) who received l-methylfolate and other vitamins via Ocufolin®, a medical food. Subjects were followed for 10-33 months by a single ophthalmologist. Ocufolin® was prescribed at the time of diagnosis and subjects remained on the regimen throughout the time of observation. Examinations were performed in an un-masked fashion at 3-month intervals with recording of best corrected ...
Source: Adv Data - April 17, 2024 Category: Epidemiology Authors: Steven Baker Dylan Baker Robert Baker Craig J Brown Source Type: research
Multimodal radionuclide shuntography for device patency: New procedural tips for anuncommon historical technique
Hell J Nucl Med. 2024 Apr 18:s002449912705. doi: 10.1967/s002449912705. Online ahead of print.ABSTRACTCerebrospinal fluid (CSF) shunting is an established long-term treatment option for hydrocephalus, and is one of the most commonly performed neurosurgical procedures in western countries.Despite advances in CSF shunt design and management, its failure rates remain high and is most commonly due to obstruction and infection.Cerebrospinal fluidshunt failure diagnosis should be prompt and accurate in establishing timely if its revision is appropriate. Radionuclide shuntography with technetium-99m-diethylenetriaminepetaacetic a...
Source: Hellenic Journal of Nuclear Medicine - April 17, 2024 Category: Nuclear Medicine Authors: Antonio Rosario Pisani Dino Rubini Corinna Altini Nicola Lucarelli Angela Gaudiano Cristina Ferrari Giuseppe Rubini Source Type: research
Historical technology transfer activities and productivity of NIDLRR grantees
Assist Technol. 2024 Apr 17:1-13. doi: 10.1080/10400435.2024.2324051. Online ahead of print.ABSTRACTThis paper analyzes the technology-related outputs from The National Institute of Disability, Independent Living, and Rehabilitation Research (NIDILRR). We seek to answer the questions: What are the types and frequency of assistive technology (AT) technology transfer (ATTT) outputs from NIDILRR grants? How does NIDILRR's ATTT generation compare to other granting organizations? What types of ATTT outputs occur, how, and what is the relative productivity of the most frequently funded universities and small businesses performin...
Source: Assistive Technology - April 17, 2024 Category: Rehabilitation Authors: Erin Higgins Michelle Zorrilla Megan D'Innocenzo Mary R Goldberg Susan K Cohen Nancy Augustine Julie Faieta Kathleen Murphy Jonathan L Pearlman Source Type: research
BIOACTIVES OF Melipona rufiventris PROPOLIS: EXPLORING ITS ANTIMICROBIAL, ANTI-INFLAMMATORY, AND ANTIOXIDANT ACTIVITIES
This study explores the potential of propolis from Melipona rufiventris species. With its composition encompassing resin, wax, pollen, and soil, propolis holds historical significance in traditional medicine within tropical regions. This research is driven by the scarcity of information surrounding M. rufiventris propolis, prompting an investigation into its chemical constituents, in vivo toxicity, and antimicrobial, antioxidant, and anti-inflammatory properties. This exploration could potentially uncover novel applications for this natural product, bolstering both meliponiculture practices and the preservation of native b...
Source: Chemistry and Biodiversity - April 17, 2024 Category: Biochemistry Authors: Amanda Tristao Santini Rayra Annara Otac ílio Pinto Josy Goldoni Lazarini Daniel Vieira de Morais Anna Maria Alves de Piloto Fernandes Marcelo Franchin Patricia Lunardelli Negreiros de Carvalho Carolina Girotto Pressete Pedro Luiz Rosalen Severino Matias Source Type: research
The Question of HIV Vaccine: Why Is a Solution Not Yet Available?
J Immunol Res. 2024 Apr 8;2024:2147912. doi: 10.1155/2024/2147912. eCollection 2024.ABSTRACTEver since its discovery, human immunodeficiency virus type 1 (HIV-1) infection has remained a significant public health concern. The number of HIV-1 seropositive individuals currently stands at 40.1 million, yet definitive treatment for the virus is still unavailable on the market. Vaccination has proven to be a potent tool in combating infectious diseases, as evidenced by its success against other pathogens. However, despite ongoing efforts and research, the unique viral characteristics have prevented the development of an effecti...
Source: Journal of Immunology Research - April 17, 2024 Category: Allergy & Immunology Authors: Martina Libera Valeria Caputo Giulia Laterza Louiza Moudoud Alessio Soggiu Luigi Bonizzi Roberta A Diotti Source Type: research
Case series of retinal vein occlusions showing early recovery using oral l-methylfolate
Ther Adv Ophthalmol. 2024 Apr 15;16:25158414241240687. doi: 10.1177/25158414241240687. eCollection 2024 Jan-Dec.ABSTRACTThis case series describes the aggregate rate of recovery in five consecutive subjects (six eyes) with retinal vein occlusion (RVO) who received l-methylfolate and other vitamins via Ocufolin®, a medical food. Subjects were followed for 10-33 months by a single ophthalmologist. Ocufolin® was prescribed at the time of diagnosis and subjects remained on the regimen throughout the time of observation. Examinations were performed in an un-masked fashion at 3-month intervals with recording of best corrected ...
Source: Adv Data - April 17, 2024 Category: Epidemiology Authors: Steven Baker Dylan Baker Robert Baker Craig J Brown Source Type: research
Outcomes of the transformation of follicular lymphoma to diffuse large B ‐cell lymphoma in the rituximab era: A population‐based study
ConclusionThe outcome of t-DLBCL in the rituximab era was better than historical series before the rituximab era. Due to the good prognosis, we did not recommend autologous stem cell transplantation for t-DLBCL receiving watch-and-wait or radiation as initial therapy before HT. (Source: Cancer Medicine)
Source: Cancer Medicine - April 17, 2024 Category: Cancer & Oncology Authors: Wenshuai Zheng,
Mingjuan Liu,
Lixun Guan,
Shenyu Wang Tags: RESEARCH ARTICLE Source Type: research
Genes, Vol. 15, Pages 504: Insights into the Geographical Origins of the Cabo Verde Green Monkey
sconcelos
The green monkey Chlorocebus sabaeus, L. 1766, native to West Africa, was introduced to the Cabo Verde Archipelago in the 16th century. Historical sources suggest that, due to the importance of Cabo Verde as a commercial entrepôt in the Atlantic slave trade, establishing the precise place of origin of this introduced species is challenging. Non-invasive fecal samples were collected from feral and captive green monkey individuals in Cabo Verde. Two mitochondrial fragments, HVRI and cyt b, were used to confirm the taxonomic identification of the species and to tentatively determine the geographic ...
Source: Genes - April 17, 2024 Category: Genetics & Stem Cells Authors: Lara Almeida Ivo Colmonero-Costeira Maria J. Ferreira da Silva Cecilia Veracini Raquel Vasconcelos Tags: Article Source Type: research
Intervention diversity predicts social rehabilitation indicators at discharge in Therapeutic Communities
The Therapeutic Community Model narrows the gap in substance use disorder's network of assistance in Brazil by offering residential treatment to socially vulnerable populations. Due to a historical lack of evidence-based approaches, the government has established treatment guidelines and has been trying to implement training and monitoring methods. (Source: Journal of Substance Abuse Treatment)
Source: Journal of Substance Abuse Treatment - April 17, 2024 Category: Addiction Authors: K átia Isicawa de Sousa Barreto, Clarice Sandi Madruga, André Constantino Miguel, Crystal Smith, Gleuda Simone Apolinário, Guilherme Sabino de Godoy Filho, Lucas Roncati Guirado, Pablo Andres Kurlander, Sterling McPherson, Ronaldo Ramos Laranjeira Source Type: research
The days we never forget: Flashbulb memories across the life span in Alzheimer's disease
We examined the frequency, characteristics, and the temporal distribution of flashbulb memories across the life span. To this aim, 28 older adults diagnosed with AD and a matched sample of 29 healthy older controls were probed for flashbulb memories for two historical events from each decade of their lives. They also estimated the subjective degree of reexperiencing for the memories reported. AD participants showed impaired access to flashbulb memories, the frequency of reported memories being lower than for healthy older adults. However, qualitative aspects of AD participants' flashbulb memories were quite similar to thos...
Source: Memory and Cognition - April 16, 2024 Category: Neuroscience Authors: Katrine W Rasmussen Marie Kirk Susanne B Overgaard Dorthe Berntsen Source Type: research
The Role of Intermediate Care in Supporting Critically Ill Patients and Critical Care Infrastructure
Intermediate care (IC) is used for patients who do not require the human and technological support of the intensive care unit (ICU) yet require more care and monitoring than can be provided on general wards. Though prevalent in many countries, there is marked variability in models of organization and staffing, as well as monitoring and interventions provided. In this article, the authors will discuss the historical background of IC, review the impact of IC on ICU and IC patient outcomes, and highlight where future studies can shed light on how to optimize IC organization and outcomes. (Source: Critical Care Clinics)
Source: Critical Care Clinics - April 16, 2024 Category: Intensive Care Authors: Aaron S. Case, Chad H. Hochberg, David N. Hager Source Type: research
