BIOACTIVES OF Melipona rufiventris PROPOLIS: EXPLORING ITS ANTIMICROBIAL, ANTI-INFLAMMATORY, AND ANTIOXIDANT ACTIVITIES
This study explores the potential of propolis from Melipona rufiventris species. With its composition encompassing resin, wax, pollen, and soil, propolis holds historical significance in traditional medicine within tropical regions. This research is driven by the scarcity of information surrounding M. rufiventris propolis, prompting an investigation into its chemical constituents, in vivo toxicity, and antimicrobial, antioxidant, and anti-inflammatory properties. This exploration could potentially uncover novel applications for this natural product, bolstering both meliponiculture practices and the preservation of native b...
Source: Chemistry and Biodiversity - April 17, 2024 Category: Biochemistry Authors: Amanda Tristao Santini Rayra Annara Otac ílio Pinto Josy Goldoni Lazarini Daniel Vieira de Morais Anna Maria Alves de Piloto Fernandes Marcelo Franchin Patricia Lunardelli Negreiros de Carvalho Carolina Girotto Pressete Pedro Luiz Rosalen Severino Matias Source Type: research

The Question of HIV Vaccine: Why Is a Solution Not Yet Available?
J Immunol Res. 2024 Apr 8;2024:2147912. doi: 10.1155/2024/2147912. eCollection 2024.ABSTRACTEver since its discovery, human immunodeficiency virus type 1 (HIV-1) infection has remained a significant public health concern. The number of HIV-1 seropositive individuals currently stands at 40.1 million, yet definitive treatment for the virus is still unavailable on the market. Vaccination has proven to be a potent tool in combating infectious diseases, as evidenced by its success against other pathogens. However, despite ongoing efforts and research, the unique viral characteristics have prevented the development of an effecti...
Source: Journal of Immunology Research - April 17, 2024 Category: Allergy & Immunology Authors: Martina Libera Valeria Caputo Giulia Laterza Louiza Moudoud Alessio Soggiu Luigi Bonizzi Roberta A Diotti Source Type: research

Case series of retinal vein occlusions showing early recovery using oral l-methylfolate
Ther Adv Ophthalmol. 2024 Apr 15;16:25158414241240687. doi: 10.1177/25158414241240687. eCollection 2024 Jan-Dec.ABSTRACTThis case series describes the aggregate rate of recovery in five consecutive subjects (six eyes) with retinal vein occlusion (RVO) who received l-methylfolate and other vitamins via Ocufolin®, a medical food. Subjects were followed for 10-33 months by a single ophthalmologist. Ocufolin® was prescribed at the time of diagnosis and subjects remained on the regimen throughout the time of observation. Examinations were performed in an un-masked fashion at 3-month intervals with recording of best corrected ...
Source: Adv Data - April 17, 2024 Category: Epidemiology Authors: Steven Baker Dylan Baker Robert Baker Craig J Brown Source Type: research

Outcomes of the transformation of follicular lymphoma to diffuse large B ‐cell lymphoma in the rituximab era: A population‐based study
ConclusionThe outcome of t-DLBCL in the rituximab era was better than historical series before the rituximab era. Due to the good prognosis, we did not recommend autologous stem cell transplantation for t-DLBCL receiving watch-and-wait or radiation as initial therapy before HT. (Source: Cancer Medicine)
Source: Cancer Medicine - April 17, 2024 Category: Cancer & Oncology Authors: Wenshuai Zheng, Mingjuan Liu, Lixun Guan, Shenyu Wang Tags: RESEARCH ARTICLE Source Type: research

Genes, Vol. 15, Pages 504: Insights into the Geographical Origins of the Cabo Verde Green Monkey
sconcelos The green monkey Chlorocebus sabaeus, L. 1766, native to West Africa, was introduced to the Cabo Verde Archipelago in the 16th century. Historical sources suggest that, due to the importance of Cabo Verde as a commercial entrepôt in the Atlantic slave trade, establishing the precise place of origin of this introduced species is challenging. Non-invasive fecal samples were collected from feral and captive green monkey individuals in Cabo Verde. Two mitochondrial fragments, HVRI and cyt b, were used to confirm the taxonomic identification of the species and to tentatively determine the geographic ...
Source: Genes - April 17, 2024 Category: Genetics & Stem Cells Authors: Lara Almeida Ivo Colmonero-Costeira Maria J. Ferreira da Silva Cecilia Veracini Raquel Vasconcelos Tags: Article Source Type: research