Volume expansion mitigates Shiga toxin-producing E. coli-hemolytic uremic syndrome in children
ConclusionsThis study suggests that volume expansion may be associated with the mitigation of the acute course of STEC-HUS, especially severe neurological involvement and the development of CKD. Prospective trials should lead to standardized protocols for volume expansion in children with STEC-HUS.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - April 19, 2024 Category: Urology & Nephrology Source Type: research

Hospice at Home: Historical Perspectives and Their Implications for End-of-Life Care Today
1. Describe critical influences in the development of the Medicare hospice benefit.2. Apply a historical approach to reflect on reasons for socioeconomic disparities in end-of-life care today. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Helen P. Knight, Richard E. Leiter Source Type: research

Unilateral Do-Not-Attempt-Resuscitation Orders: How Did We Get Here and Where Are We Going?
1. Utilizing a case-based approach, participants will self-report an understanding of the historical context of cardiopulmonary resuscitation, do-not-attempt-resuscitation (DNAR) orders, and unilateral do-not-attempt-resuscitation (UDNAR) orders.2. Utilizing a case-based approach, participants will self report a knowledge of the ethical principles involved with UDNAR orders as well as concerns for unequal utilization of UDNAR orders for underserved populations. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Adam Marks, Joseph D. Dixon Source Type: research

Wild Swings of the Pendulum: The Estranged Surrogate Decision Maker in the ICU
1. Gain an understanding of substituted judgment and its historical context in American healthcare.2. Learn effective strategies for eliciting substituted judgment from surrogate decision-makers and develop insights into the dynamics of estrangement and recommended clinician responses when dealing with estranged families in medical decision-making. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Amtul M. Malik, Laura Hofmann, Maleeha Ruhi, Elizabeth L. Cobbs, Mona S. Wilson Source Type: research

The Alluring, Enduring, and Troubling Concept of a “Good Death” in Pediatric Palliative Care
1. Using a critical historical approach, participants will evaluate why, how, and for/with who the “good death” concept emerged and how it has persisted over time.2. The interprofessional authorship team will illustrate and deconstruct the “good death” concept into actionable components that can be used to improve clinical care and research inquiry. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Elizabeth G. Broden, Sarah McCarthy, Jennifer M. Snaman Source Type: research

Clinical Perspectives on Cancer and Palliative Care Access among Native Hawaiian/Pacific Islander Veterans
1. Along with understanding sources for rising cancer prevalence among Veterans of Native Hawaiian/Pacific Islander heritage, participants will be able to identify strategies to address geographic, logistical, and financial challenges, as well as effects of historical trauma, that may be exacerbating cancer health disparities.2. By using an indigenous framework to health, participants will learn to culturally adapt clinical practices to address mistrust and build a therapeutic relationship with Veterans of Native Hawaiian/Pacific Islander heritage. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Nainwant Singh, Akanksha Jain, Sara Kaushik, Olivia de Moraes, Troy Helenihi, Karl Lorenz, Karleen F. Giannitrapani, Ranak Trivedi Source Type: research

Total Pain: Euphemism and Mission Drift in the Treatment of Non-Physical Pain
1. Describe the historical meaning of “total pain,” and its application in current practice.2. Identify euphemism as a rhetorical form, and to see it as an invitation to consider the hidden, stigmatized, and under-examined. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Anna DeForest, Stephen B. Douglas Source Type: research

Inflammatory breast cancer: Epidemiologic data and therapeutic results
In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to younger age (less than 50 years) with rapid evolution of signs and symptoms (in less than 3 up to 6 months), and more aggressive clinical and histopathological-molecular parameters, due to the predominance of triple-negative and HER2+ subtypes in around 60% of cases. An epidemiologic trend was observed in both high and low incidence areas since the ei...
Source: International Review of Cell and Molecular Biology - April 18, 2024 Category: Cytology Authors: Hamouda Boussen Yosra Berrazaga None Sherif Kullab Maroua Manai Narjess Berrada Nesrine Mejri Ismail Siala Paul H Levine Massimo Cristofanilli Source Type: research

MDH volume 68 issue 1 Cover and Front matter
Med Hist. 2024 Jan;68(1):f1. doi: 10.1017/mdh.2024.16. Epub 2024 Apr 18.NO ABSTRACTPMID:38632886 | DOI:10.1017/mdh.2024.16 (Source: Medical History)
Source: Medical History - April 18, 2024 Category: History of Medicine Source Type: research

The history of Ervin Bauer's publications on the theory of life
Biosystems. 2024 Apr 16:105212. doi: 10.1016/j.biosystems.2024.105212. Online ahead of print.ABSTRACTErvin Bauer (1890-1938) made historical contributions to contemporary biology, provided a new definition of life, defined the contents of theoretical biology. He worked in different countries, perturbed by deep historical events. These historical events necessarily impacted his fate and finally led to the violent loss of his life and the life of his wife. His work and with it his theory of life had a no less complicated history than the history of his personal life. Bauer's main work "Theoretical Biology" was published in 1...
Source: Biosystems - April 18, 2024 Category: Biotechnology Authors: Mikl ós Müller G ábor Elek Source Type: research

Inflammatory breast cancer: Epidemiologic data and therapeutic results
In this study, we reviewed the literature using the Surveillance, Epidemiology, and End Results (SEER) database compared to other published series. We observed that in the high incidence areas (North of Africa) when compared to "classical" breast cancer, IBC was associated to younger age (less than 50 years) with rapid evolution of signs and symptoms (in less than 3 up to 6 months), and more aggressive clinical and histopathological-molecular parameters, due to the predominance of triple-negative and HER2+ subtypes in around 60% of cases. An epidemiologic trend was observed in both high and low incidence areas since the ei...
Source: Mol Biol Cell - April 18, 2024 Category: Molecular Biology Authors: Hamouda Boussen Yosra Berrazaga None Sherif Kullab Maroua Manai Narjess Berrada Nesrine Mejri Ismail Siala Paul H Levine Massimo Cristofanilli Source Type: research

Beyond exposure: A healthy broadening of posttraumatic stress disorder treatment options: Commentary on Rubenstein et al. (2024)
Am Psychol. 2024 Apr;79(3):347-349. doi: 10.1037/amp0001233.ABSTRACTThis commentary on Rubenstein et al. (2024) applauds their sensitive historical exploration of exposure therapy for posttraumatic stress disorder (PTSD) and balanced review of the strengths and weaknesses of that approach. I offer five points to expand on their contribution. (a) Stringent exposure therapy workforce requirements limit scalability, thus restricting access for the large number of patients in need of PTSD treatment. (b) There are additional non-trauma-focused approaches that show efficacy for PTSD. (c) Results of exposure therapy trials should...
Source: The American Psychologist - April 18, 2024 Category: Psychiatry & Psychology Authors: Lisa M Najavits Source Type: research

Beyond exposure: A healthy broadening of posttraumatic stress disorder treatment options: Commentary on Rubenstein et al. (2024).
American Psychologist, Vol 79(3), Apr 2024, 347-349; doi:10.1037/amp0001233This commentary on Rubenstein et al. (2024) applauds their sensitive historical exploration of exposure therapy for posttraumatic stress disorder (PTSD) and balanced review of the strengths and weaknesses of that approach. I offer five points to expand on their contribution. (a) Stringent exposure therapy workforce requirements limit scalability, thus restricting access for the large number of patients in need of PTSD treatment. (b) There are additional non-trauma-focused approaches that show efficacy for PTSD. (c) Results of exposure therapy trials...
Source: American Psychologist - April 18, 2024 Category: Psychiatry & Psychology Source Type: research

Prevalence and Types of Strabismus in Cerebral Palsy: A Global and Historical Perspective Based on a Systematic Review and Meta-Analysis
. (Source: Ophthalmic Epidemiology)
Source: Ophthalmic Epidemiology - April 18, 2024 Category: Opthalmology Authors: Michael S. HerronLingchen WangChristopher S. von Barthelda Center of Biomedical Research Excellence in Cell Biology, School of Medicine, University of Nevada, Reno, Nevada, USAb School of Public Health, University of Nevada, Reno, Nevada, USAc Department Source Type: research

The Portuguese mertolenga cattle breed: a review
AbstractThis review summarizes the state of the art regarding the phylogenetic origins, recent history and present-day main traits and uses of theMertolenga cattle breed from Southern Portugal, particularly those related to production performances and product quality. Named after the historical city of M értola, in southern Portugal, theMertolenga is one of the fifteen autochthonous bovine breeds of Portugal. It is a cattle breed thoroughly adapted to the poor Mediterranean pastures of the southern regions of the Iberian Peninsula. It is used predominantly in an extensive to semi-intensive sylvopastoral production system ...
Source: Tropical Animal Health and Production - April 18, 2024 Category: Veterinary Research Source Type: research