The Question of HIV Vaccine: Why Is a Solution Not Yet Available?
J Immunol Res. 2024 Apr 8;2024:2147912. doi: 10.1155/2024/2147912. eCollection 2024.ABSTRACTEver since its discovery, human immunodeficiency virus type 1 (HIV-1) infection has remained a significant public health concern. The number of HIV-1 seropositive individuals currently stands at 40.1 million, yet definitive treatment for the virus is still unavailable on the market. Vaccination has proven to be a potent tool in combating infectious diseases, as evidenced by its success against other pathogens. However, despite ongoing efforts and research, the unique viral characteristics have prevented the development of an effecti...
Source: Journal of Immunology Research - April 17, 2024 Category: Allergy & Immunology Authors: Martina Libera Valeria Caputo Giulia Laterza Louiza Moudoud Alessio Soggiu Luigi Bonizzi Roberta A Diotti Source Type: research
Historical technology transfer activities and productivity of NIDLRR grantees
Assist Technol. 2024 Apr 17:1-13. doi: 10.1080/10400435.2024.2324051. Online ahead of print.ABSTRACTThis paper analyzes the technology-related outputs from The National Institute of Disability, Independent Living, and Rehabilitation Research (NIDILRR). We seek to answer the questions: What are the types and frequency of assistive technology (AT) technology transfer (ATTT) outputs from NIDILRR grants? How does NIDILRR's ATTT generation compare to other granting organizations? What types of ATTT outputs occur, how, and what is the relative productivity of the most frequently funded universities and small businesses performin...
Source: Assistive Technology - April 17, 2024 Category: Rehabilitation Authors: Erin Higgins Michelle Zorrilla Megan D'Innocenzo Mary R Goldberg Susan K Cohen Nancy Augustine Julie Faieta Kathleen Murphy Jonathan L Pearlman Source Type: research
Blood Pressure Regulation and Hypertension in Obstructive Sleep Apnea Syndrome: A Historical Perspective
Intern Med. 2024 Apr 16. doi: 10.2169/internalmedicine.2960-23. Online ahead of print.ABSTRACTIn obstructive sleep apnea syndrome (OSAS), an underlying disease of secondary hypertension, repeated episodes of asphyxia due to obstructive sleep apnea (OSA), followed by arousal, lead to various cardiovascular consequences. Using a canine model of OSAS, it was found that a single load of OSA caused an abrupt increase in blood pressure (BP) (Apnea Surge in seconds), while multiple OSA episodes occurring nightly for 1-3 months led to a sustained elevation of BP during both nighttime and daytime. Epidemiological studies on 24-hour...
Source: Internal Medicine - April 17, 2024 Category: Internal Medicine Authors: Fumihiko Yasuma Akiko Noda Junichiro Hayano Source Type: research
Leonard Rowntree, Louis Wilson, Fielding Garrison, and the origins of teaching medical history at the Mayo Clinic
Proc (Bayl Univ Med Cent). 2024 Feb 28;37(3):493-500. doi: 10.1080/08998280.2024.2314448. eCollection 2024.ABSTRACTA visiting surgeon described his disappointment with an aspect of the Mayo Clinic in 1914, stating that there was "the almost lack of anything that could be dignified by the term 'lecture.'" One year later, the Mayo Foundation for Medical Education and Research was founded. By 1917, the foundation declared history of medicine a graduate-level subject, and history of medicine questions were included in final oral examinations. In 1920 and 1921, lectures were given on historical topics; however, these lectures p...
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Nathaniel P Rogers Christopher J Boes Source Type: research
Historical technology transfer activities and productivity of NIDLRR grantees
Assist Technol. 2024 Apr 17:1-13. doi: 10.1080/10400435.2024.2324051. Online ahead of print.ABSTRACTThis paper analyzes the technology-related outputs from The National Institute of Disability, Independent Living, and Rehabilitation Research (NIDILRR). We seek to answer the questions: What are the types and frequency of assistive technology (AT) technology transfer (ATTT) outputs from NIDILRR grants? How does NIDILRR's ATTT generation compare to other granting organizations? What types of ATTT outputs occur, how, and what is the relative productivity of the most frequently funded universities and small businesses performin...
Source: Assistive Technology - April 17, 2024 Category: Rehabilitation Authors: Erin Higgins Michelle Zorrilla Megan D'Innocenzo Mary R Goldberg Susan K Cohen Nancy Augustine Julie Faieta Kathleen Murphy Jonathan L Pearlman Source Type: research
The Question of HIV Vaccine: Why Is a Solution Not Yet Available?
J Immunol Res. 2024 Apr 8;2024:2147912. doi: 10.1155/2024/2147912. eCollection 2024.ABSTRACTEver since its discovery, human immunodeficiency virus type 1 (HIV-1) infection has remained a significant public health concern. The number of HIV-1 seropositive individuals currently stands at 40.1 million, yet definitive treatment for the virus is still unavailable on the market. Vaccination has proven to be a potent tool in combating infectious diseases, as evidenced by its success against other pathogens. However, despite ongoing efforts and research, the unique viral characteristics have prevented the development of an effecti...
Source: Journal of Immunology Research - April 17, 2024 Category: Allergy & Immunology Authors: Martina Libera Valeria Caputo Giulia Laterza Louiza Moudoud Alessio Soggiu Luigi Bonizzi Roberta A Diotti Source Type: research
Leonard Rowntree, Louis Wilson, Fielding Garrison, and the origins of teaching medical history at the Mayo Clinic
Proc (Bayl Univ Med Cent). 2024 Feb 28;37(3):493-500. doi: 10.1080/08998280.2024.2314448. eCollection 2024.ABSTRACTA visiting surgeon described his disappointment with an aspect of the Mayo Clinic in 1914, stating that there was "the almost lack of anything that could be dignified by the term 'lecture.'" One year later, the Mayo Foundation for Medical Education and Research was founded. By 1917, the foundation declared history of medicine a graduate-level subject, and history of medicine questions were included in final oral examinations. In 1920 and 1921, lectures were given on historical topics; however, these lectures p...
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Nathaniel P Rogers Christopher J Boes Source Type: research
Blood Pressure Regulation and Hypertension in Obstructive Sleep Apnea Syndrome: A Historical Perspective
Intern Med. 2024 Apr 16. doi: 10.2169/internalmedicine.2960-23. Online ahead of print.ABSTRACTIn obstructive sleep apnea syndrome (OSAS), an underlying disease of secondary hypertension, repeated episodes of asphyxia due to obstructive sleep apnea (OSA), followed by arousal, lead to various cardiovascular consequences. Using a canine model of OSAS, it was found that a single load of OSA caused an abrupt increase in blood pressure (BP) (Apnea Surge in seconds), while multiple OSA episodes occurring nightly for 1-3 months led to a sustained elevation of BP during both nighttime and daytime. Epidemiological studies on 24-hour...
Source: Internal Medicine - April 17, 2024 Category: Internal Medicine Authors: Fumihiko Yasuma Akiko Noda Junichiro Hayano Source Type: research
Once upon a time in Anatolia: the kings with bulging eyes
Hormones (Athens). 2024 Apr 18. doi: 10.1007/s42000-024-00561-y. Online ahead of print.ABSTRACTThe Hittite Empire, formed by the Hittites who settled in central Anatolia at the beginning of the second millennium BC, has left behind rich archeological remains. In this historical review, statues of the Hittite priest-kings, King Idrimi, King Šuppiluliuma, and King Tarhunza, who ruled in these lands in ancient times, are analyzed. Graves' disease (GD) is the most common cause of hyperthyroidism. Patients with GD are also at risk of developing Graves' orbitopathy (GO). Upper eyelid retraction and exophthalmos (bulging eyes) a...
Source: Hormones - April 17, 2024 Category: Endocrinology Authors: Hulya Elbe Source Type: research
Multimodal radionuclide shuntography for device patency: New procedural tips for anuncommon historical technique
Hell J Nucl Med. 2024 Apr 18:s002449912705. doi: 10.1967/s002449912705. Online ahead of print.ABSTRACTCerebrospinal fluid (CSF) shunting is an established long-term treatment option for hydrocephalus, and is one of the most commonly performed neurosurgical procedures in western countries.Despite advances in CSF shunt design and management, its failure rates remain high and is most commonly due to obstruction and infection.Cerebrospinal fluidshunt failure diagnosis should be prompt and accurate in establishing timely if its revision is appropriate. Radionuclide shuntography with technetium-99m-diethylenetriaminepetaacetic a...
Source: Hellenic Journal of Nuclear Medicine - April 17, 2024 Category: Nuclear Medicine Authors: Antonio Rosario Pisani Dino Rubini Corinna Altini Nicola Lucarelli Angela Gaudiano Cristina Ferrari Giuseppe Rubini Source Type: research
The Question of HIV Vaccine: Why Is a Solution Not Yet Available?
J Immunol Res. 2024 Apr 8;2024:2147912. doi: 10.1155/2024/2147912. eCollection 2024.ABSTRACTEver since its discovery, human immunodeficiency virus type 1 (HIV-1) infection has remained a significant public health concern. The number of HIV-1 seropositive individuals currently stands at 40.1 million, yet definitive treatment for the virus is still unavailable on the market. Vaccination has proven to be a potent tool in combating infectious diseases, as evidenced by its success against other pathogens. However, despite ongoing efforts and research, the unique viral characteristics have prevented the development of an effecti...
Source: Journal of Immunology Research - April 17, 2024 Category: Allergy & Immunology Authors: Martina Libera Valeria Caputo Giulia Laterza Louiza Moudoud Alessio Soggiu Luigi Bonizzi Roberta A Diotti Source Type: research
Multimodal radionuclide shuntography for device patency: New procedural tips for anuncommon historical technique
Hell J Nucl Med. 2024 Apr 18:s002449912705. doi: 10.1967/s002449912705. Online ahead of print.ABSTRACTCerebrospinal fluid (CSF) shunting is an established long-term treatment option for hydrocephalus, and is one of the most commonly performed neurosurgical procedures in western countries.Despite advances in CSF shunt design and management, its failure rates remain high and is most commonly due to obstruction and infection.Cerebrospinal fluidshunt failure diagnosis should be prompt and accurate in establishing timely if its revision is appropriate. Radionuclide shuntography with technetium-99m-diethylenetriaminepetaacetic a...
Source: Hellenic Journal of Nuclear Medicine - April 17, 2024 Category: Nuclear Medicine Authors: Antonio Rosario Pisani Dino Rubini Corinna Altini Nicola Lucarelli Angela Gaudiano Cristina Ferrari Giuseppe Rubini Source Type: research
BIOACTIVES OF Melipona rufiventris PROPOLIS: EXPLORING ITS ANTIMICROBIAL, ANTI-INFLAMMATORY, AND ANTIOXIDANT ACTIVITIES
This study explores the potential of propolis from Melipona rufiventris species. With its composition encompassing resin, wax, pollen, and soil, propolis holds historical significance in traditional medicine within tropical regions. This research is driven by the scarcity of information surrounding M. rufiventris propolis, prompting an investigation into its chemical constituents, in vivo toxicity, and antimicrobial, antioxidant, and anti-inflammatory properties. This exploration could potentially uncover novel applications for this natural product, bolstering both meliponiculture practices and the preservation of native b...
Source: Chemistry and Biodiversity - April 17, 2024 Category: Biochemistry Authors: Amanda Tristao Santini Rayra Annara Otac ílio Pinto Josy Goldoni Lazarini Daniel Vieira de Morais Anna Maria Alves de Piloto Fernandes Marcelo Franchin Patricia Lunardelli Negreiros de Carvalho Carolina Girotto Pressete Pedro Luiz Rosalen Severino Matias Source Type: research
Historical technology transfer activities and productivity of NIDLRR grantees
Assist Technol. 2024 Apr 17:1-13. doi: 10.1080/10400435.2024.2324051. Online ahead of print.ABSTRACTThis paper analyzes the technology-related outputs from The National Institute of Disability, Independent Living, and Rehabilitation Research (NIDILRR). We seek to answer the questions: What are the types and frequency of assistive technology (AT) technology transfer (ATTT) outputs from NIDILRR grants? How does NIDILRR's ATTT generation compare to other granting organizations? What types of ATTT outputs occur, how, and what is the relative productivity of the most frequently funded universities and small businesses performin...
Source: Assistive Technology - April 17, 2024 Category: Rehabilitation Authors: Erin Higgins Michelle Zorrilla Megan D'Innocenzo Mary R Goldberg Susan K Cohen Nancy Augustine Julie Faieta Kathleen Murphy Jonathan L Pearlman Source Type: research
Leonard Rowntree, Louis Wilson, Fielding Garrison, and the origins of teaching medical history at the Mayo Clinic
Proc (Bayl Univ Med Cent). 2024 Feb 28;37(3):493-500. doi: 10.1080/08998280.2024.2314448. eCollection 2024.ABSTRACTA visiting surgeon described his disappointment with an aspect of the Mayo Clinic in 1914, stating that there was "the almost lack of anything that could be dignified by the term 'lecture.'" One year later, the Mayo Foundation for Medical Education and Research was founded. By 1917, the foundation declared history of medicine a graduate-level subject, and history of medicine questions were included in final oral examinations. In 1920 and 1921, lectures were given on historical topics; however, these lectures p...
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Nathaniel P Rogers Christopher J Boes Source Type: research
