A variant of uncertain significance of the HMGA2 gene in a child with Silver-Russell syndrome-like phenotype: a case report
Hormones (Athens). 2024 May 24. doi: 10.1007/s42000-024-00562-x. Online ahead of print.ABSTRACTSilver-Russell syndrome 5 (SRS5) is characterized by asymmetric intrauterine growth restriction (IUGR), poor postnatal growth, macrocephaly at birth, and feeding difficulties. Other possible features include triangular shaped face, prominent forehead, hypertelorism, epicanthus, micrognathia, brachydactyly, clinodactyly of the 5th finger, and syndactyly of the 2nd and 3rd toes. Pathogenic variants of the HMGA2 (high mobility group AT-hook 2) gene, on chromosome 12q14, which regulates the transcription of growth factor IGF2, have r...
Source: Hormones - May 24, 2024 Category: Endocrinology Authors: Evangelos Bourousis Maria Xatzipsalti Ioulia Polychroni Emmanouil Kanavakis Lela Stamoyannou Source Type: research

The co-occurrence of SAT, hypophysitis, and Schnitzler syndrome after COVID-19 vaccination: the first described  case
Hormones (Athens). 2024 May 22. doi: 10.1007/s42000-024-00567-6. Online ahead of print.ABSTRACTSubacute thyroiditis (also known as granulomatous thyroiditis, giant cell thyroiditis, de Quervain's disease, or SAT) is an inflammatory disease of the thyroid gland, usually spontaneously remitting, that lasts for weeks to months. However, recurrent forms sometimes occur which may have a genetic basis. In our paper, we have focused on the pathogenetics, symptoms, and treatment of SAT. We have described the 17-month disease course of a woman with persistent recurrent steroid-resistant SAT. SAT was well established and the patient...
Source: Hormones - May 22, 2024 Category: Endocrinology Authors: Micha ł Szklarz Katarzyna Gontarz-Nowak Aleksander Kiero ński Krystian Golon Jan G órny Wojciech Matuszewski El żbieta Bandurska-Stankiewicz Source Type: research

A schedule for tapering glucocorticoid treatment in patients with severe SARS-CoV 2 infection can prevent acute adrenal insufficiency in the geriatric population
CONCLUSIONS: A structured schedule for the tapering of GC treatment used in patients with severe COVID-19 can reduce the risk of adrenal crisis and acute adrenal insufficiency.PMID:38758491 | DOI:10.1007/s42000-024-00564-9 (Source: Hormones)
Source: Hormones - May 17, 2024 Category: Endocrinology Authors: Irene Tizianel Elena Ruggiero Marianna Torchio Matteo Simonato Chiara Seresin Francesco Bigolin Ilaria Pivetta Botta Giulia Bano Mario Rosario Lo Storto Carla Scaroni Filippo Ceccato Source Type: research

The interlink between thyroid autoimmunity and type 1 diabetes and the impact on male and female fertility
In conclusion, although it is now well-known that both diabetes and thyroid diseases can affect fertility, only a few data are available on possible effects of autoimmune conditions. Recent findings nevertheless point to the importance of screening patients with immunologic infertility for AITDs and T1D, and vice versa.PMID:38748060 | DOI:10.1007/s42000-024-00563-w (Source: Hormones)
Source: Hormones - May 15, 2024 Category: Endocrinology Authors: Sanja Medenica Vukasin Stojanovic Umberto Capece Rossella Mazzilli Milica Markovic Virginia Zamponi Tanja Vojinovic Silvia Migliaccio Giuseppe Defeudis Francesca Cinti Source Type: research

The role of low glycemic index and load diets in medical nutrition therapy for type 2 diabetes: an update
Hormones (Athens). 2024 May 16. doi: 10.1007/s42000-024-00566-7. Online ahead of print.ABSTRACTThe increasing prevalence of type 2 diabetes mellitus (T2DM) and its microvascular and macrovascular complications necessitate an optimal approach to prevention and management. Medical nutrition therapy serves as the cornerstone of diabetes care, reducing reliance on diabetic medications for glycemic control and mitigating cardiovascular risk. The broadening field of research in the effect of low glycemic index (GI) and/or glycemic load (GL) diets on individuals with T2DM has yielded promising results in the existing literature. ...
Source: Hormones - May 15, 2024 Category: Endocrinology Authors: Eleni Gerontiti Almog Shalit Katerina Stefanaki Paraskevi Kazakou Dimitrios S Karagiannakis Melpomeni Peppa Theodora Psaltopoulou Stavroula A Paschou Source Type: research

The interlink between thyroid autoimmunity and type 1 diabetes and the impact on male and female fertility
In conclusion, although it is now well-known that both diabetes and thyroid diseases can affect fertility, only a few data are available on possible effects of autoimmune conditions. Recent findings nevertheless point to the importance of screening patients with immunologic infertility for AITDs and T1D, and vice versa.PMID:38748060 | DOI:10.1007/s42000-024-00563-w (Source: Hormones)
Source: Hormones - May 15, 2024 Category: Endocrinology Authors: Sanja Medenica Vukasin Stojanovic Umberto Capece Rossella Mazzilli Milica Markovic Virginia Zamponi Tanja Vojinovic Silvia Migliaccio Giuseppe Defeudis Francesca Cinti Source Type: research

The role of low glycemic index and load diets in medical nutrition therapy for type 2 diabetes: an update
Hormones (Athens). 2024 May 16. doi: 10.1007/s42000-024-00566-7. Online ahead of print.ABSTRACTThe increasing prevalence of type 2 diabetes mellitus (T2DM) and its microvascular and macrovascular complications necessitate an optimal approach to prevention and management. Medical nutrition therapy serves as the cornerstone of diabetes care, reducing reliance on diabetic medications for glycemic control and mitigating cardiovascular risk. The broadening field of research in the effect of low glycemic index (GI) and/or glycemic load (GL) diets on individuals with T2DM has yielded promising results in the existing literature. ...
Source: Hormones - May 15, 2024 Category: Endocrinology Authors: Eleni Gerontiti Almog Shalit Katerina Stefanaki Paraskevi Kazakou Dimitrios S Karagiannakis Melpomeni Peppa Theodora Psaltopoulou Stavroula A Paschou Source Type: research

The interlink between thyroid autoimmunity and type 1 diabetes and the impact on male and female fertility
In conclusion, although it is now well-known that both diabetes and thyroid diseases can affect fertility, only a few data are available on possible effects of autoimmune conditions. Recent findings nevertheless point to the importance of screening patients with immunologic infertility for AITDs and T1D, and vice versa.PMID:38748060 | DOI:10.1007/s42000-024-00563-w (Source: Hormones)
Source: Hormones - May 15, 2024 Category: Endocrinology Authors: Sanja Medenica Vukasin Stojanovic Umberto Capece Rossella Mazzilli Milica Markovic Virginia Zamponi Tanja Vojinovic Silvia Migliaccio Giuseppe Defeudis Francesca Cinti Source Type: research

Corticotropin-releasing hormone deficiency results in impaired analgesic response during CFA-induced inflammation
CONCLUSION: Our data suggest that genetic deficiency of CRH is associated with increased pain. This effect is likely attributable to the accompanying glucocorticoid insufficiency and is in part mediated by opioids expressed locally.PMID:38740711 | DOI:10.1007/s42000-024-00565-8 (Source: Hormones)
Source: Hormones - May 13, 2024 Category: Endocrinology Authors: Efthymia Karagianni Olga Rassouli Smaragda Poulaki Eirini Dermitzaki George Liapakis Andrew N Margioris Maria Venihaki Source Type: research