Role of endothelial cell receptors in the context of SARS-CoV-2 infection (COVID-19)
Proc (Bayl Univ Med Cent). 2021 Jan 26;34(2):262-268. doi: 10.1080/08998280.2021.1874231.ABSTRACTEndothelial cell (EC) dysfunction contributes to COVID-19-associated vascular inflammation and coagulopathy, and the angiotensin-converting enzyme 2 (ACE2) receptor plays a role in EC dysfunction in COVID-19. To expand the understanding of the role of the ACE2 receptor relative to EC dysfunction, this review addresses (1) tissue distribution of the ACE2 protein and its mRNA expression in humans, (2) susceptibility of the capillary ECs to SARS-CoV-2 infection, and (3) the role of EC dysfunction relevant to ACE2 and nuclear facto...
Source: Baylor University Medical Center Proceedings - March 5, 2021 Category: Universities & Medical Training Authors: Jun Zhang Kristen M Tecson Peter A McCullough Source Type: research

Gangrenous appendicitis contained within a Spigelian hernia
Proc (Bayl Univ Med Cent). 2020 Oct 5;34(1):104-106. doi: 10.1080/08998280.2020.1822131.ABSTRACTA 66-year-old man with abdominal pain had a 5-year-old mass subsequently identified as a Spigelian hernia. Exploratory laparotomy revealed a strangulated and gangrenous appendix contained within the hernia, necessitating an appendectomy. This case highlights the importance of early identification and exploration of this rare hernia, so that early management can prevent the development of more serious and dangerous symptoms.PMID:33456162 | PMC:PMC7785144 | DOI:10.1080/08998280.2020.1822131 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Rohan Anand Jasmin Rahesh John Ciubuc Karla Esparza-Leal Abbie Schuster Roy Jacob Steven E Brooks Robyn Richmond Catherine A Ronaghan Source Type: research

Atraumatic spontaneous hemorrhagic cholecystitis
We present an atypical case of spontaneous hemorrhagic cholecystitis with no antecedent risk factors.PMID:33456163 | PMC:PMC7785188 | DOI:10.1080/08998280.2020.1829961 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Jasmin Rahesh Rohan Anand John Ciubuc Vincent Athas Steven Brooks Catherine Ronaghan Source Type: research

Gastric bleeding in giant cell arteritis
We report the case of an elderly man who presented with sharp substernal pain, dizziness, and visual changes. He was initially hypotensive and anemic, and imaging showed hemoperitoneum with possible extravasation. Celiac and gastric angiography demonstrated findings consistent with vasculitis and focal extravasation from a left gastric branch. Subsequent embolization was performed. After the procedure, the patient informed the care team that he had biopsy-proven GCA. Extracranial, celiac/mesenteric arteriopathy is a less common manifestation of GCA, and few reported cases include hemoperitoneum or involvement of second-ord...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Austin Childress Thomas J Kwarcinski Joseph Scott H Bittle Clayton Trimmer Source Type: research

Bowel perforation from malignant atrophic papulosis treated with eculizumab
We present the case of a 57-year-old man with known cutaneous manifestations of malignant atrophic papulosis, also known as Köhlmeier-Degos disease, who developed an almost-fatal small bowel perforation following a parathyroidectomy. He required two surgical interventions during his initial hospitalization and was started on eculizumab. Despite these therapies, the patient developed recurrent bowel perforations and ultimately died.PMID:33456165 | PMC:PMC7785204 | DOI:10.1080/08998280.2020.1809942 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Ajithraj Sathiyaraj Priyanga Jayakumar Matthew R McGlennon John F Eckford Sandy Itwaru Anne Source Type: research

Refractory dermatomyositis-systemic lupus erythematosus overlap syndrome and response to tofacitinib
We present a case of a 39-year-old woman who presented with a facial rash, arthralgias, and lower-extremity edema and steadily progressed to develop severe proximal muscle weakness and hair loss over the course of a 2.5-month hospitalization. After diagnostic testing, she was found to have a dermatomyositis-systemic lupus erythematosus overlap syndrome. Her symptoms were refractory to initial medical management but finally resolved once she was switched to tofacitinib.PMID:33456167 | PMC:PMC7785137 | DOI:10.1080/08998280.2020.1821589 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Preston Williams Benjamin McKinney Source Type: research

Usefulness of nivolumab plus ipilimumab immunotherapy for metastatic uveal melanoma
Proc (Bayl Univ Med Cent). 2020 Oct 19;34(1):118-119. doi: 10.1080/08998280.2020.1825587.ABSTRACTA 53-year-old woman with known localized uveal melanoma presented with pain from a large destructive lesion of the left iliac bone. Biopsy confirmed metastatic melanoma, and positron emission tomography scan showed extensive osseous destruction. Because her uveal melanoma was successfully treated with brachytherapy 15 years earlier, next-generation sequencing was performed, and a GNAQ mutation proved the lesion to be of uveal origin. Uveal melanoma has a worse prognosis than cutaneous melanoma. We initiated treatment with the c...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Brittany Miles John Moth James Mackey Source Type: research

Dermatomyositis, pembrolizumab, and squamous cell carcinoma of the lung
Proc (Bayl Univ Med Cent). 2020 Aug 27;34(1):120-121. doi: 10.1080/08998280.2020.1811189.ABSTRACTCancer immunotherapy has impacted the treatment of numerous tumor types, including skin, lung, and colon cancers. Immune checkpoint inhibitors (ICI) activate the immune system to attack cancer cells, but this mechanism can also impact healthy cells. Dermatomyositis, an autoimmune syndrome affecting multiple organ systems, is often associated with cancer as a paraneoplastic syndrome, but this syndrome can also be induced by ICI. Here, we describe a case of dermatomyositis in a patient receiving pembrolizumab for treatment of squ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Claire J Wiggins Susan Y Chon Source Type: research

A paraneoplastic syndrome exacerbated by checkpoint inhibition therapy
In this report, we present a case of polymyalgia rheumatica presenting as a paraneoplastic syndrome that was exacerbated during therapy with immune checkpoint inhibitors for recurrent melanoma.PMID:33456171 | PMC:PMC7785140 | DOI:10.1080/08998280.2020.1824962 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Heather Villarreal Kathryn H Dao Source Type: research

Spontaneous tumor lysis syndrome in squamous cell carcinoma of the lung
Proc (Bayl Univ Med Cent). 2020 Sep 28;34(1):128-130. doi: 10.1080/08998280.2020.1818911.ABSTRACTTumor lysis syndrome (TLS) is an oncologic emergency, more commonly occurring in patients with hematologic malignancies receiving cancer-directed therapy due to massive cellular breakdown. Spontaneous TLS is rare and occurs in the absence of cancer-directed therapy. Herein, we present a case of spontaneous TLS associated with squamous cell carcinoma.PMID:33456173 | PMC:PMC7785206 | DOI:10.1080/08998280.2020.1818911 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Mohammad Ammad Ud Din Syed Ather Hussain Leela Krishna Teja Boppana Dharmini Manogna Farhan Imran Source Type: research

Catastrophic complications following cryoablation of lung cancer
We report a patient with non-small cell lung cancer who developed a bronchocutaneous fistula, persistent empyema, and chest wall abscess a month after cryoablation. With this case report, we aim to sensitize physicians to such complications.PMID:33456174 | PMC:PMC7785183 | DOI:10.1080/08998280.2020.1830333 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Vrinda Vyas Manju Paul Source Type: research

A perianal subcutaneous metastasis as the presenting sign for lung cancer
We report a case of a 77-year-old white man who presented with a 9-day history of a painful, rapidly growing mass on his left buttock in the gluteal cleft. The deep dermal location of the neoplasm and the lack of epidermal involvement led to suspicion of a metastatic carcinoma. Imaging showed a lung lesion suspected to be a primary malignancy with distant liver and gastric fundus metastases. Lung pathology showed primarily adenocarcinoma with squamous differentiation, whereas the skin biopsy showed poorly differentiated squamous cell carcinoma. Clinically, we concluded the skin carcinoma was a metastasis of a primary lung ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Aaminah Azhar Elizabeth Wilder Source Type: research

Stage IV colorectal cancer presenting after necrotizing soft tissue infection
We present a case of CRC diagnosed more than 4 years after the development of NSTI. There are documented cases of NSTIs concomitant with a preexisting CRC. In this case, however, the patient's initial presentation was an NSTI followed by later diagnosis of CRC. A previously treated NSTI that is not healing appropriately may be an early indicator for CRC.PMID:33456176 | PMC:PMC7785173 | DOI:10.1080/08998280.2020.1805675 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Caroline Freedle Jasmin Rahesh Michelle Harris Virginia Tran Sharmila Dissanaike Source Type: research

Giant cell tumor of the sacrum
We present a case of giant cell tumor of the sacrum and subsequent treatment with preoperative embolization, L5 to S4 laminectomy, partial sacrectomy, intraoperative thermal ablation, and L4 to pelvis stabilization and fusion.PMID:33456178 | PMC:PMC7785148 | DOI:10.1080/08998280.2020.1801327 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: James Rizkalla Brendan Holderread Jonathan Liu Al Mollabashy Ishaq Y Syed Source Type: research

Gold laser removal of a large ductal cyst on the laryngeal surface of the epiglottis
We report an unusual presentation of a large ductal cyst located on the laryngeal surface of the epiglottis. The patient presented with a low tone voice while displaying bilateral normal appearing vocal cords with normal mobility. Computed tomography scans and flexible laryngoscopy showed a round supraglottic mass approximately 2 cm in diameter on the right lateral laryngeal surface of the epiglottis. The mass was removed surgically during microsuspension laryngoscopy with excision of the mucocele utilizing a gold laser. Postoperatively, the patient's voice returned to baseline with no complications.PMID:33456180 | PMC:PMC...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Brooke Jensen Evan Nix Pranati Pillutla Joehassin Cordero Source Type: research

Hiatal hernia repair and magnetic sphincter augmentation to treat laryngopharyngeal reflux aiding the prevention of recurrent laryngeal cancer
We present a patient with a squamous cell cancer of the larynx who was diagnosed with gastroesophageal reflux disease (GERD) and found to have LPR. The cancer was treated locally and GERD was eradicated with magnetic sphincter augmentation. After 15 months of follow-up, there was no residual cancer. This case highlights the role that untreated LPR may play in patients' risk of developing laryngeal cancer.PMID:33456181 | PMC:PMC7785177 | DOI:10.1080/08998280.2020.1818167 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Madeline Smoot Marc A Ward Lindsey Arviso Christine E Sanchez Steven G Leeds Source Type: research

Extrapulmonary sarcoidosis in an atypical patient demographic
This article describes osseous, hepatic, and cutaneous manifestations due to sarcoidosis. The patient was diagnosed with sarcoidosis, treated with a dynamic hip screw implant with a derotational screw, and discharged on a new medication regimen: vitamin D, calcium supplements, alendronate, methotrexate, and hydroxychloroquine.PMID:33456182 | PMC:PMC7785207 | DOI:10.1080/08998280.2020.1824963 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Trisha Modi Ganesh Maniam Miguel Quirch Irfan Warraich Shabnam Rehman Source Type: research

Evolution and regression of imaging findings in treated pulmonary Langerhans cell histiocytosis
Proc (Bayl Univ Med Cent). 2020 Oct 5;34(1):156-158. doi: 10.1080/08998280.2020.1823790.ABSTRACTIn rare instances, pediatric Langerhans cell histiocytosis (LCH) may manifest as lung disease. While the imaging features at presentation have been reported, we present sequential computed tomography (CT) scans of a 3-year-old boy with pulmonary LCH, revealing the evolution and regression of the disease. Sequential CT scans during treatment demonstrated variable evolution of pulmonary cysts, including changes in size, thinning of walls, and a pattern of collapse into irregular nodules and involution. Our case represents a rare o...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Mimi Phan Krista L Birkemeier Matthew Crisp Jose Santiago Nicholas William McGregor Source Type: research

Secondary erythrocytosis due to hemoglobin San Diego
Proc (Bayl Univ Med Cent). 2020 Oct 6;34(1):159-160. doi: 10.1080/08998280.2020.1824980.ABSTRACTHigh-oxygen-affinity hemoglobin variants are a rare clinical entity that can present with secondary erythrocytosis. Herein, the author reports a case of a 41-year-old man with a 4-year history of secondary erythrocytosis of unknown etiology. Physical examination was unremarkable except for plethora of the palms. Myeloproliferative neoplasms and common causes of secondary erythrocytosis were ruled out. The P50 oxygen-hemoglobin dissociation curve was left shifted. Hemoglobin electrophoresis was silent; however, globin mass spectr...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Thein Hlaing Oo Source Type: research

Incidental rhabdomyomatous mesenchymal hamartoma
We report a case of a solitary RMH on the midline upper chest in a healthy 15-year-old girl.PMID:33456186 | PMC:PMC7785171 | DOI:10.1080/08998280.2020.1801087 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Christine P Lin Jeannie M Nguyen Sina Aboutalebi Cloyce L Stetson Source Type: research

Turner syndrome and autosomal dominant polycystic kidney disease
We present a case of a young girl with Turner syndrome and associated short stature on growth hormone treatment who presented with cystic renal disease found to be autosomal dominant kidney disease. We propose reevaluation of renal screening guidelines in this population due to the potential association of growth hormone and cyst proliferation.PMID:33456188 | PMC:PMC7785201 | DOI:10.1080/08998280.2020.1838182 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Rachel Styer Matthew Stephen Faris Hashim Krista Birkemeier Source Type: research

Usefulness of acetazolamide in the management of diuretic resistance
We present a case wherein urine output improved significantly with acetazolamide. Although the diuretic capacity of acetazolamide is weak on its own, it might be efficient in aiding the efficacy of loop diuretics. We discuss the pathophysiological basis and evidence behind its potential role in diuretic resistance. Drawing from current understanding, we propose a stepwise approach to diuresis in such patients.PMID:33456189 | PMC:PMC7785193 | DOI:10.1080/08998280.2020.1830332 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Dalvir Gill Naga Vaishnavi Gadela Ayesha Azmeen Abhishek Jaiswal Source Type: research

Cardiac tamponade as a complication of bronchogenic cyst
Proc (Bayl Univ Med Cent). 2020 Aug 21;34(1):172-174. doi: 10.1080/08998280.2020.1795594.ABSTRACTBronchogenic cysts are rare incidental findings, but they can have life-threatening complications. Herein, we report a case of a 44-year-old man who presented with complaints of left-sided chest pain, intermittent dyspnea, and pink-tinged sputum. Computed tomography angiography of the chest revealed a large cystic mediastinal mass in the subcarinal location. During his hospital stay, the patient became hypotensive with jugular venous distention and muffled heart sounds on auscultation. A stat echocardiogram depicted a large per...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Noman Lateef Jason Kuniyoshi Azka Latif Muhammad Junaid Ahsan Kashif Shaikh Bradley DeVrieze Aiman Smer Ahmed Aboeata Source Type: research

Subacute stent thrombosis in a patient with COVID-19 pneumonia
We present a case of a patient with COVID-19 infection who presented with pneumonia, acute respiratory failure, and non-ST elevation myocardial infarction. Reperfusion was achieved with coronary angioplasty and drug-eluting stent placement, and the patient was started on aspirin and clopidogrel. However, 72 hours later, the patient experienced an episode of subacute stent thrombosis. This raises concerns about a possible association between stent thrombosis and increased thrombogenicity and platelet aggregability triggered by COVID-19 infection.PMID:33456191 | PMC:PMC7785200 | DOI:10.1080/08998280.2020.1812792 (Source: Bay...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Mohamed Ayan Swathi Kovelamudi Malek Al-Hawwas Source Type: research

Ascending aortic thrombus with multiple emboli associated with COVID-19
We describe a patient with an ascending aortic thrombus resulting in multiple emboli treated by multiple modalities.PMID:33456192 | PMC:PMC7785187 | DOI:10.1080/08998280.2020.1834342 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Portia Schmidt Javier Vasquez Bryce Gagliano Alastair J Moore Charles S Roberts Source Type: research

Asymptomatic ventricular fibrillation in peripartum cardiomyopathy with a left ventricular assist device
We present a 43-year-old woman with peripartum cardiomyopathy with a left ventricular assist device (LVAD) and recalcitrant right-sided heart failure who presented with unsuccessful defibrillator shocks. The patient was asymptomatic while in persistent VF for over 4 hours. Echocardiography showed the heart to be in asystole. We hypothesize that a combination of chronic right heart failure and LVAD kept her asymptomatic. Patients supported with LVAD can survive prolonged periods with VF.PMID:33456193 | PMC:PMC7785202 | DOI:10.1080/08998280.2020.1829947 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Elie P Dib Paul A Grayburn Amarinder Bindra Source Type: research

The utility of boxing for cardiac prehabilitation
Proc (Bayl Univ Med Cent). 2020 Sep 28;34(1):182-184. doi: 10.1080/08998280.2020.1818050.ABSTRACTA 56-year-old man with end-stage heart failure performed a 4-week, symptom-limited, progressive inpatient cardiac prehabilitation program while confined to the cardiovascular intensive care unit awaiting heart transplantation. Mobility was limited by an acute gout flare and multiple central venous access lines. He received a tailored prescription of intermittent boxing, supervised hallway ambulation, stair training, and golfing on a putting green on four consecutive weekdays and was encouraged to mobilize with nursing on the re...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Katelyn D Brown Jenny Adams Dan M Meyer Robert L Gottlieb Shelley A Hall Source Type: research

Statin-induced necrotizing autoimmune myopathy
We present a case of SINAM that was successfully treated with intravenous immunoglobulin.PMID:33456195 | PMC:PMC7785182 | DOI:10.1080/08998280.2020.1831298 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Syed A Huda Sanjay Yadava Sara Kahlown Muhammad S Farooqi Stephanie Bryant Ronald Russo Source Type: research

Vascular extravasation of injectable bioresorbable bone cement during aspiration and injection of calcaneal bone cyst
Proc (Bayl Univ Med Cent). 2020 Aug 27;34(1):189-190. doi: 10.1080/08998280.2020.1801105.ABSTRACTA 27-year-old woman underwent aspiration and bioresorbable cement injection of a simple bone cyst. During injection, cement was seen on fluoroscopy extravasating into the posterior vein of the ankle. The procedure was immediately stopped, and the patient remained hemodynamically stable. Vascular leakage of bone cement during injection of a bone cyst is rare but can have catastrophic consequences.PMID:33456197 | PMC:PMC7785199 | DOI:10.1080/08998280.2020.1801105 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Dorian Wood Allaaddin Mollabashy Source Type: research

Treatment approach for primary hyperparathyroidism in pregnancy
Proc (Bayl Univ Med Cent). 2020 Oct 28;34(1):191-193. doi: 10.1080/08998280.2020.1834791.ABSTRACTPrimary hyperparathyroidism is rare in pregnancy, with an incidence of 1%. It is associated with maternal, fetal, and neonatal complications. Herein, we present two patients with gestational primary hyperparathyroidism who failed medical management and underwent successful parathyroidectomy. Based on our experience and review of the literature, gestational hyperparathyroidism appears to be a clear indication for early parathyroidectomy in both symptomatic and asymptomatic patients.PMID:33456198 | PMC:PMC7785157 | DOI:10.1080/08...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Azka Latif Alheli Arce Gastelum Kinaan Farhan Sunil Jagadesh Sangeeta Mutnuri Source Type: research

The Texas Society of Pathologists: molded by the legacy of pathology and focused on excellence in medicine for 100 years and beyond
This article aims to both commemorate the TSP centennial and to provide context for the remarkable success of the society. The article takes a look back and a look forward from 1921. The look back focuses on the development of the field of pathology and the maturation of medicine and pathology in the USA and Texas. The look forward encompasses developments in science, technology, American health care policy, and medicine that have impacted Texas pathologists and influenced proactive initiatives of the TSP. The review of the life and times of the TSP highlights the importance of leaders and leadership in shaping outcomes. C...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: L Maximilian Buja Source Type: research

High-quality cardiac surgery through teamwork
Proc (Bayl Univ Med Cent). 2020 Sep 14;34(1):215-220. doi: 10.1080/08998280.2020.1811057.ABSTRACTThe high-quality cardiothoracic surgery program is primed for mindful effective surgery. The challenge lies in attaining mindful skills and efficiency. Herein is one journey toward high departmental quality over two decades.PMID:33456201 | PMC:PMC7785160 | DOI:10.1080/08998280.2020.1811057 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Baron L Hamman A Carl Henry Robert F Hebeler Aldo E Rafael Gonzalo V Gonzalez-Stawinski Daniel H Enter Aaron Mercado-Reza Bobbi Leeper Charles S Roberts Source Type: research

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Proc (Bayl Univ Med Cent). 2020 Oct 28;34(1):221-222. doi: 10.1080/08998280.2020.1826267.NO ABSTRACTPMID:33456202 | PMC:PMC7785145 | DOI:10.1080/08998280.2020.1826267 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Walker Mainwaring Ethan B Ludmir Soo Jung Kim Source Type: research

Reflections upon receiving a Lifetime Achievement Award
Proc (Bayl Univ Med Cent). 2020 Aug 26;34(1):223-227. doi: 10.1080/08998280.2020.1811593.NO ABSTRACTPMID:33456203 | PMC:PMC7785192 | DOI:10.1080/08998280.2020.1811593 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: John Davis Cantwell Source Type: research

Safe implementation of enhanced recovery after surgery protocol in transfemoral transcatheter aortic valve replacement
Proc (Bayl Univ Med Cent). 2020 Sep 23;34(1):5-10. doi: 10.1080/08998280.2020.1810198.ABSTRACTEnhanced recovery after surgery (ERAS) protocols are gaining wide acceptance. We evaluated ERAS protocol implementation in transfemoral transcatheter aortic valve replacement (TAVR) patients. The ERAS protocol included (1) moderate sedation or general anesthesia with on-table extubation, (2) no pulmonary artery or urinary catheters, (3) arterial line removal within 4 hours, (4) no postoperative narcotics, (5) mobilization at 4 hours and ambulation within 8 hours, and (6) antihypertensive reinstitution without nodal blockers. Patie...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Molly Szerlip Deborah Tabachnick Mohanad Hamandi LuAnn Caras Allison T Lanfear John J Squiers Katherine Harrington Srinivasa P Potluri J Michael DiMaio Jordan Wooley Benjamin Pollock Justin M Schaffer William T Brinkman David L Brown Michael J Mack Source Type: research

Relation of hematologic inflammatory markers and obesity in otherwise healthy participants in the National Health and Nutrition Examination Survey, 2011-2016
This study investigated the association between hematologic inflammatory markers derived from complete blood counts and obesity. We undertook a cross-sectional study that included self-reported healthy subjects above the age of 18 years from the 2011-2016 National Health and Nutrition Examination Survey, a US population database. Study parameters included mean corpuscular volume, red cell distribution width, mean platelet volume, total platelet count, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic immune-inflammation index. Body mass index was used as an index of obesity and was correlated with ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Subhanudh Thavaraputta Jeff A Dennis Somedeb Ball Passisd Laoveeravat Kenneth Nugent Source Type: research

Relation of length of stay and other hospital variables to posttraumatic stress disorder and depression after orthopedic trauma
This study examined the relationship between injury- and hospital-related variables and PTSD and depression at baseline and 12 months after orthopedic trauma. This longitudinal, prospective cohort study examined adult orthopedic trauma patients admitted ≥24 hours to a level I trauma center. Non-English/Spanish-speaking and cognitively impaired patients were excluded. The Primary Care PTSD screen and PTSD Checklist-Civilian version assessed PTSD, and the Patient Health Questionnaire 8-Item assessed depression. Demographic and hospital-related variables were examined (e.g., hospital length of stay, Injury Severity Score, ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Jordin K Shelley Jacob W Roden-Foreman David Vier Evan Elizabeth McShan Monica M Bennett Alan L Jones Ann Marie Warren Source Type: research

Pediatric asthma pathway in the emergency room
Proc (Bayl Univ Med Cent). 2020 Aug 21;34(1):40-43. doi: 10.1080/08998280.2020.1801110.ABSTRACTAsthma is one of the leading causes of hospital admission in the pediatric population. Standardization of asthma management guidelines for patients admitted to the emergency department has been suggested to improve care delivery and patient outcomes. Utilizing a multidisciplinary asthma task force at a single academic medical center, we sought to determine if a protocol-driven approach to implementation of care for patients with asthma could improve patient outcomes by reducing wait times for administration of steroids. A prospec...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Dominic Lucia James Cain Ashlee Porter Malvika Sagar Sarah Blazovic Leland Finley Lea Mallett Source Type: research

Atherogenic index of plasma as a marker of cardiovascular risk factors in Mexicans aged 18 to 22 years
Proc (Bayl Univ Med Cent). 2020 Aug 21;34(1):22-27. doi: 10.1080/08998280.2020.1799479.ABSTRACTThe aim of this cross-sectional study was to evaluate the use and application of the atherogenic index of plasma (AIP) in the prediction of cardiovascular risk factors including mixed hyperlipidemia, hypertension, hyperuricemia, and metabolic syndrome in a population of young Mexican adults. Values were obtained for metabolic parameters, such as glucose, triglycerides, cholesterol (total, high-density, low-density, and very low density), systolic and diastolic blood pressure, and uric acid. Through univariate and multivariate ana...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Ashuin Kammar-Garc ía Patricia L ópez-Moreno Mar ía Elena Hernández-Hernández Ang élica María Ortíz-Bueno Mar ía de Lurdez Consuelo Martínez-Montaño Source Type: research

Utility of oxcarbazepine in the treatment of childhood and adolescent psychiatric symptoms
Proc (Bayl Univ Med Cent). 2020 Oct 6;34(1):34-39. doi: 10.1080/08998280.2020.1826259.ABSTRACTThe primary aims of this study were to determine if oxcarbazepine is a safely tolerated option for treatment of psychiatric symptoms in children and whether its use facilitates dose modification of other psychotropic medications. A retrospective chart review was completed using data extracted from the electronic medical record of a large outpatient child psychiatry clinic. A total of 507 of 740 children prescribed oxcarbazepine for psychiatric indications for 3 months or more had adequate data to assess clinical responses and medi...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Kyle Morrow Keith A Young Shawn Spencer Edgar Samuel Medina Michaela A Marziale Alejandro Sanchez James A Bourgeois Source Type: research

Leg ulceration with histological features of pseudoxanthoma elasticum
We present a case of ulceration and lipodermatosclerosis in the setting of venous insufficiency alongside histological features of PXE.PMID:33456154 | PMC:PMC7785143 | DOI:10.1080/08998280.2020.1826247 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Usman Asad Sheevam Shah Palak Parekh Source Type: research

Dipeptidyl-peptidase-like protein 6 encephalitis treated with immunotherapy
Proc (Bayl Univ Med Cent). 2020 Sep 28;34(1):114-115. doi: 10.1080/08998280.2020.1822132.ABSTRACTThis case describes a middle-aged man with anti-dipeptidyl-peptidase-like protein 6 (DPPX) encephalitis who exhibited the triad of memory loss, diarrhea, and tremor. The progression of his disease resembled neurodegenerative disease, and his first presentation at our department was 2 years after the first onset of symptoms. Antibodies against DPPX were positive in both serum and cerebrospinal fluid. No related tumor was found. The patient was initially treated with corticosteroid therapy and plasmapheresis. Despite moderate res...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Lan Ye Margret Schnegelsberg Mark Obermann Source Type: research

Anti-CTLA-4 therapy-associated granuloma annulare in chronic myelomonocytic leukemia
Proc (Bayl Univ Med Cent). 2020 Sep 28;34(1):122-123. doi: 10.1080/08998280.2020.1818165.ABSTRACTImmune checkpoint inhibitor (ICI) therapies activate the immune system to unmask cancer cells that the body might otherwise not detect. These cancer therapies alter the immune system at different "checkpoint" proteins such as PD-1, PD-L1, or CTLA-4 to better target tumor cells, but also have the potential to affect normal tissues. In patients receiving ICI therapy, cutaneous reactions have been frequently documented, ranging from mild urticarial rashes to widespread cutaneous necrosis. Proper identification and manage...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Claire J Wiggins Susan Y Chon Source Type: research

Pediatric spontaneous tension pneumothorax in Langerhans cell histiocytosis
We present the case of a 3-year-old boy who presented for tachypnea and chest pain with cough, rhinorrhea, and congestion. He was discharged with a diagnosis of upper respiratory infection. The patient returned to the emergency department and was found to have a tension pneumothorax, which was emergently treated with thoracostomy. The subsequent workup revealed Langerhans cell histiocytosis with pulmonary disease and jaw involvement. Although tension pneumothorax is often associated with trauma, several medical conditions are predispositional.PMID:33456172 | PMC:PMC7787669 | DOI:10.1080/08998280.2020.1826215 (Source: Baylo...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Andrew L Juergens Archana K Reddy Matthew W Fannell Guy H Grayson Source Type: research

Chylous ascites in cirrhosis from retroperitoneal lymphoma
We describe a case of a 74-year-old man with cirrhosis from nonalcoholic steatohepatitis who presented with worsening abdominal distension and chylous ascites on paracentesis; an infiltrating retroperitoneal lymphoma was subsequently detected on computed tomography imaging.PMID:33456177 | PMC:PMC7785197 | DOI:10.1080/08998280.2020.1814597 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Rahul Hegde Ayah Megahed Prabin Sharma Anas Bamashmos Ian Karol Source Type: research

Primitive neuroectodermal tumor of the pancreas
Proc (Bayl Univ Med Cent). 2020 Oct 19;34(1):144-145. doi: 10.1080/08998280.2020.1826760.ABSTRACTPrimitive neuroectodermal tumors (PNETs) are rare small round cell malignancies closely related to Ewing's sarcoma. Involvement of the abdominal cavity, specifically the pancreas, is extremely rare. PNETs affect predominantly children and young adults. The clinical presentation is mostly vague, with a short history of symptoms even in metastatic disease. Findings on imaging studies are nonspecific. The diagnosis can be suggested by the microscopic appearance of the tumor cells, but should be confirmed by histology, immunohistoc...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Ted George Achufusi Raman Sohal Ernesto Zamora Prateek Harne Ronald Russo Source Type: research

Hemophagocytic syndrome with histiocytic glomerulopathy associated with ovarian serous carcinoma
We report a case of histiocytic glomerulopathy in a woman receiving chemotherapy for ovarian serous carcinoma with proteinuria in whom hemophagocytic syndrome was not clinically suspected.PMID:33456183 | PMC:PMC7785209 | DOI:10.1080/08998280.2020.1805715 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Wesley Hiser Michael Landgarten Xin Jin Zhou Source Type: research

A brown tumor secondary to hyperparathyroidism in the maxilla, skull, scapula, and femora
We describe a 35-year-old woman who presented with a left mandibular mass that rapidly enlarged over 3 weeks. Radiological, histological, and biochemical investigations led to the diagnosis of brown tumor secondary to primary hyperparathyroidism. A neck ultrasound revealed a 1.5 × 2.3 × 4.6 cm mass at the lower pole of the left thyroid lobe, suggestive of a parathyroid adenoma. Bone scan showed additional abnormal foci of increased uptake in the maxilla, both femora, skull, and scapula. Brown tumors are treated primarily by correcting the underlying endocrine disorder, and a parathyroidectomy was performed.PMID...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Alison Psaila Luca Conti Alexander P Azzopardi David V Coppini Source Type: research

Cardiopulmonary resuscitation-induced consciousness
We present a patient who demonstrated purposeful movements suggesting consciousness during cardiopulmonary resuscitation that would repeatedly abate with cessation of chest compressions.PMID:33456196 | PMC:PMC7785208 | DOI:10.1080/08998280.2020.1823799 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Raman P Singh Soumya Adhikari David Landsberg Viren Kaul Source Type: research

Sir William Osler, eugenics, racism, and the < em > Komagata Maru < /em > incident
Proc (Bayl Univ Med Cent). 2020 Nov 9;34(1):194-198. doi: 10.1080/08998280.2020.1843380.ABSTRACTA recent critic levels two new charges against Sir William Osler: (1) that in 1912 he was a vice president of the First International Eugenics Congress; and (2) that in 1914 he asserted Canada should remain a "a white man's country." Osler was indeed among the 31 vice presidents of the First International Eugenics Congress, but he did nothing further in this area. Osler indeed asserted that Canada should remain a "white man's country," but his context was the Komagata Maru incident during which most Canadians...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Charles S Bryan Source Type: research