Accuracy of hepatobiliary scintigraphy and added value of SPECT/CT versus planar imaging for diagnosing biliary atresia
Hell J Nucl Med. 2021 May-Aug;24(2):108-113. doi: 10.1967/s002449912350. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Hepatobiliary scintigraphy (HBS) is an important tool in diagnosing biliary atresia in infants. There is limited evidence on the use of single photon emission computed tomography/computed tomography (SPECT/CT) as an additional imaging method to planar imaging. We evaluated the value of SPECT/CT in unclear cases of planar HBS.SUBJECTS AND METHODS: Consecutive patients with suspected biliary atresia who underwent guideline-compliant HBS from January 2010 until March 2020 were reviewed, and cases with SPECT/CT were iden...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Trine Borup Andersen Ramune Aleksyniene Lars Borup Petersen Source Type: research

Myocardial perfusion SPECT as a potential mediator on circulating chromogranin A in patients with old myocardial infarction
Hell J Nucl Med. 2021 May-Aug;24(2):114-121. doi: 10.1967/s002449912351. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Chromogranin A (CgA) is a soluble polypeptide stored within and released from secretory granules of endocrine and other cell types (including cardiomyocytes); CgA appears to be a marker of the overall neuroendocrine activity. Increased levels of serum CgA have been found not only in patients with neuroendocrine neoplasms but also with other malignancies, hypertension, myocardial infarction, heart, or renal failure.SUBJECTS AND METHODS: A population of 307 patients (202 males, 105 females) was enrolled. The study grou...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Xanthi Xourgia Spyridon Tsiouris Theofilos Kolettis Ioannis Goudevenos Angelos Arseniou Andreas D Fotopoulos Source Type: research

Is SUVmax a useful marker for progression-free survival in patients with metastatic GEP-NET receiving < sup > 177 < /sup > Lu-DOTATATE therapy?
CONCLUSION: The pre-treatment SUVmax values of 68Ga-DOTATATE PET/CT in lesions are a potential prognostic factor for PFS in well-differentiated gastroenteropancreatic neuroendocrine tumors undergoing 177Lu-DOTATATE treatment, and could be a useful parameter for the treatment selection.PMID:34352047 | DOI:10.1967/s002449912352 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Fatih Teker Umut Elboga Source Type: research

< sup > 18 < /sup > F-FDG PET/CT for assessing of disease activity of idiopathic inflammatory myopathies. A systematic review and meta-analysis
CONCLUSION: Fluorine-18-FDG PET/CT has a good performance for the detection of active disease status in patients with IM. Although there are no guidelines for adopting imaging techniques, more objective and updated criteria for the assessment of disease activity incorporated with 18F-FDG PET/CT should be introduced and validated. Further studies are necessary to determine if 18F-FDG PET/CT-based treatment of IM can improve outcomes.PMID:34352048 | DOI:10.1967/s002449912353 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Keunyoung Kim Seong Jang Kim Source Type: research

Pancreatic metastasis from papillary thyroid carcinoma: Case report and literature review
Hell J Nucl Med. 2021 May-Aug;24(2):140-148. doi: 10.1967/s002449912354. Epub 2021 Aug 6.ABSTRACTPapillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy. Papillary thyroid carcinoma generally spreads locally to the cervical lymph nodes, but distant metastases are seen in 5%-7% of cases. Most distant metastases occur in the bone, lung, and brain. Pancreatic metastases of PTC are extremely rare. Herein we present a patient with PTC treated with total thyroidectomy and two rounds of radioactive iodine (RAI) ablation that was subsequently found to have a pancreaticmetastasis detected on fluorine-18-fluo...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Rachel Stein Taylor S Harmon Caitlin E Harmon Enoch Kuo Savas Ozdemir Source Type: research

MRI and < sup > 18 < /sup > F-FDG PET/CT findings of a giant cell tumor of the tendon sheath of the knee joint (pigmented villonodular synovitis): A case report and literature review
We present a case of a 33-year-old female hospitalized with a 3-month history of right knee pain when squatting. Her physical examination showed no resting pain or local skin fever. Magnetic resonance imaging (MRI) showed multiple nodular long T1 and short T2 abnormal signal shadows in the popliteal fossa region. A patchy T2 high signal shadow was found in the soft tissue around the right knee.Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed multiple soft tissue density nodules around and within the right knee joint (largest 20x13mm) with a maximum standardized uptak...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Xue Liu Huaiwei Xu Tao Jiang Bao Zhang Youcheng Li Wenbing Zeng Source Type: research

Heterogeneous radioiodine uptake in breast fibroadenoma: A case report
Hell J Nucl Med. 2021 May-Aug;24(2):155-156. doi: 10.1967/s002449912356. Epub 2021 Aug 6.NO ABSTRACTPMID:34352051 | DOI:10.1967/s002449912356 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Lingzhi Cao Fanhui Yang Wanxing Gou Jianping Xie Source Type: research

Thymic MALT lymphoma mimicking parathyroid adenoma uptake on < sup > 99m < /sup > Tc-MIBI parathyroid scintigraphy
Hell J Nucl Med. 2021 May-Aug;24(2):157-158. doi: 10.1967/s002449912357. Epub 2021 Aug 6.NO ABSTRACTPMID:34352052 | DOI:10.1967/s002449912357 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Fanhui Yang Zongxi He Lingzhi Cao Jianping Xie Source Type: research

HER-2 breast cancer treatment induced mediastinal sarcoid like reaction depicted on < sup > 18 < /sup > F-FDG PET/CT
Hell J Nucl Med. 2021 May-Aug;24(2):159-160. doi: 10.1967/s002449912358. Epub 2021 Aug 6.ABSTRACTThis is a case of a woman with breast cancer, who developed mediastinal sarcoid-like reaction, depicted on PET/CT, which was histologically confirmed, following treatment with trastuzumab and pertuzumab. The development of noncaseating granulomas in patients who do not fulfill the criteria for systemic sarcoidosis is known as sarcoid-like reaction, having been described in association with trastuzumab in a few case reports, but none with pertuzumab. Physicians should be aware of the potentially higher rate of sarcoid-like react...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Emmanouil Panagiotidis Anna Paschali Anna Andreadou Vassiliki Chatzipavlidou Source Type: research

Unusual unilateral renal mass with pulmonary multiple nodules as the initial presentation of granulomatosis with polyangiitis
We report a case of a 32-year-old man with recurrent fever, cough and left lumbago for more than one month. Computed tomography (CT) and magnetic resonance imaging (MRI) found bilateral multiple pulmonary nodules and a tumor-like mass in the left kidney. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed increased uptake in the right pharyngeal recess along with pulmonary and renal hypermetabolic lesions. The pathologic findings of pulmonary and renal specimens were suggestive of granulomatous inflammatory changes. Further laboratory examinations showed an elevated lev...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Hongyuan Dai Fanglan Li Rui Huang Source Type: research

Primary diffuse large B-cell lymphoma of seminal vesicles detected by < sup > 18 < /sup > F-FDG PET/CT
Hell J Nucl Med. 2021 May-Aug;24(2):163-164. doi: 10.1967/s002449912360. Epub 2021 Aug 6.NO ABSTRACTPMID:34352055 | DOI:10.1967/s002449912360 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Weidong Gong Xiao Yang Junhao Wu Lei Ou Chunyin Zhang Source Type: research

Whole body planar and 3D quantitative imaging after < sup > 177 < /sup > Lu-DOTATATE on CZT SPECT/CT device with MEHRS collimator. First report
We present here in the first reported images acquired with a new collimator designed for CZT gamma-camera compared to a conventional sodium iodide (NaI) (Tl) gamma-camera. Post-therapeutic 177Lu-DOTATATE imaging on a CZT device with a medium energy high resolution (MEHRS)-collimator are promising and support the widespread of both 177Lu-based peptide-receptor radionuclide therapy (PRRT) and CZT gamma-cameras.PMID:34352056 | DOI:10.1967/s002449912361 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Emmanuel Deshayes Cyril Fersing K évin Hébert Manuel Bardies Pierre Olivier Kotzki Lore Santoro Source Type: research

Accuracy of hepatobiliary scintigraphy and added value of SPECT/CT versus planar imaging for diagnosing biliary atresia
Hell J Nucl Med. 2021 May-Aug;24(2):108-113. doi: 10.1967/s002449912350. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Hepatobiliary scintigraphy (HBS) is an important tool in diagnosing biliary atresia in infants. There is limited evidence on the use of single photon emission computed tomography/computed tomography (SPECT/CT) as an additional imaging method to planar imaging. We evaluated the value of SPECT/CT in unclear cases of planar HBS.SUBJECTS AND METHODS: Consecutive patients with suspected biliary atresia who underwent guideline-compliant HBS from January 2010 until March 2020 were reviewed, and cases with SPECT/CT were iden...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Trine Borup Andersen Ramune Aleksyniene Lars Borup Petersen Source Type: research

Myocardial perfusion SPECT as a potential mediator on circulating chromogranin A in patients with old myocardial infarction
Hell J Nucl Med. 2021 May-Aug;24(2):114-121. doi: 10.1967/s002449912351. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Chromogranin A (CgA) is a soluble polypeptide stored within and released from secretory granules of endocrine and other cell types (including cardiomyocytes); CgA appears to be a marker of the overall neuroendocrine activity. Increased levels of serum CgA have been found not only in patients with neuroendocrine neoplasms but also with other malignancies, hypertension, myocardial infarction, heart, or renal failure.SUBJECTS AND METHODS: A population of 307 patients (202 males, 105 females) was enrolled. The study grou...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Xanthi Xourgia Spyridon Tsiouris Theofilos Kolettis Ioannis Goudevenos Angelos Arseniou Andreas D Fotopoulos Source Type: research

Is SUVmax a useful marker for progression-free survival in patients with metastatic GEP-NET receiving < sup > 177 < /sup > Lu-DOTATATE therapy?
CONCLUSION: The pre-treatment SUVmax values of 68Ga-DOTATATE PET/CT in lesions are a potential prognostic factor for PFS in well-differentiated gastroenteropancreatic neuroendocrine tumors undergoing 177Lu-DOTATATE treatment, and could be a useful parameter for the treatment selection.PMID:34352047 | DOI:10.1967/s002449912352 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Fatih Teker Umut Elboga Source Type: research

< sup > 18 < /sup > F-FDG PET/CT for assessing of disease activity of idiopathic inflammatory myopathies. A systematic review and meta-analysis
CONCLUSION: Fluorine-18-FDG PET/CT has a good performance for the detection of active disease status in patients with IM. Although there are no guidelines for adopting imaging techniques, more objective and updated criteria for the assessment of disease activity incorporated with 18F-FDG PET/CT should be introduced and validated. Further studies are necessary to determine if 18F-FDG PET/CT-based treatment of IM can improve outcomes.PMID:34352048 | DOI:10.1967/s002449912353 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Keunyoung Kim Seong Jang Kim Source Type: research

Pancreatic metastasis from papillary thyroid carcinoma: Case report and literature review
Hell J Nucl Med. 2021 May-Aug;24(2):140-148. doi: 10.1967/s002449912354. Epub 2021 Aug 6.ABSTRACTPapillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy. Papillary thyroid carcinoma generally spreads locally to the cervical lymph nodes, but distant metastases are seen in 5%-7% of cases. Most distant metastases occur in the bone, lung, and brain. Pancreatic metastases of PTC are extremely rare. Herein we present a patient with PTC treated with total thyroidectomy and two rounds of radioactive iodine (RAI) ablation that was subsequently found to have a pancreaticmetastasis detected on fluorine-18-fluo...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Rachel Stein Taylor S Harmon Caitlin E Harmon Enoch Kuo Savas Ozdemir Source Type: research

MRI and < sup > 18 < /sup > F-FDG PET/CT findings of a giant cell tumor of the tendon sheath of the knee joint (pigmented villonodular synovitis): A case report and literature review
We present a case of a 33-year-old female hospitalized with a 3-month history of right knee pain when squatting. Her physical examination showed no resting pain or local skin fever. Magnetic resonance imaging (MRI) showed multiple nodular long T1 and short T2 abnormal signal shadows in the popliteal fossa region. A patchy T2 high signal shadow was found in the soft tissue around the right knee.Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed multiple soft tissue density nodules around and within the right knee joint (largest 20x13mm) with a maximum standardized uptak...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Xue Liu Huaiwei Xu Tao Jiang Bao Zhang Youcheng Li Wenbing Zeng Source Type: research

Heterogeneous radioiodine uptake in breast fibroadenoma: A case report
Hell J Nucl Med. 2021 May-Aug;24(2):155-156. doi: 10.1967/s002449912356. Epub 2021 Aug 6.NO ABSTRACTPMID:34352051 | DOI:10.1967/s002449912356 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Lingzhi Cao Fanhui Yang Wanxing Gou Jianping Xie Source Type: research

Thymic MALT lymphoma mimicking parathyroid adenoma uptake on < sup > 99m < /sup > Tc-MIBI parathyroid scintigraphy
Hell J Nucl Med. 2021 May-Aug;24(2):157-158. doi: 10.1967/s002449912357. Epub 2021 Aug 6.NO ABSTRACTPMID:34352052 | DOI:10.1967/s002449912357 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Fanhui Yang Zongxi He Lingzhi Cao Jianping Xie Source Type: research

HER-2 breast cancer treatment induced mediastinal sarcoid like reaction depicted on < sup > 18 < /sup > F-FDG PET/CT
Hell J Nucl Med. 2021 May-Aug;24(2):159-160. doi: 10.1967/s002449912358. Epub 2021 Aug 6.ABSTRACTThis is a case of a woman with breast cancer, who developed mediastinal sarcoid-like reaction, depicted on PET/CT, which was histologically confirmed, following treatment with trastuzumab and pertuzumab. The development of noncaseating granulomas in patients who do not fulfill the criteria for systemic sarcoidosis is known as sarcoid-like reaction, having been described in association with trastuzumab in a few case reports, but none with pertuzumab. Physicians should be aware of the potentially higher rate of sarcoid-like react...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Emmanouil Panagiotidis Anna Paschali Anna Andreadou Vassiliki Chatzipavlidou Source Type: research

Unusual unilateral renal mass with pulmonary multiple nodules as the initial presentation of granulomatosis with polyangiitis
We report a case of a 32-year-old man with recurrent fever, cough and left lumbago for more than one month. Computed tomography (CT) and magnetic resonance imaging (MRI) found bilateral multiple pulmonary nodules and a tumor-like mass in the left kidney. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed increased uptake in the right pharyngeal recess along with pulmonary and renal hypermetabolic lesions. The pathologic findings of pulmonary and renal specimens were suggestive of granulomatous inflammatory changes. Further laboratory examinations showed an elevated lev...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Hongyuan Dai Fanglan Li Rui Huang Source Type: research

Primary diffuse large B-cell lymphoma of seminal vesicles detected by < sup > 18 < /sup > F-FDG PET/CT
Hell J Nucl Med. 2021 May-Aug;24(2):163-164. doi: 10.1967/s002449912360. Epub 2021 Aug 6.NO ABSTRACTPMID:34352055 | DOI:10.1967/s002449912360 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Weidong Gong Xiao Yang Junhao Wu Lei Ou Chunyin Zhang Source Type: research

Whole body planar and 3D quantitative imaging after < sup > 177 < /sup > Lu-DOTATATE on CZT SPECT/CT device with MEHRS collimator. First report
We present here in the first reported images acquired with a new collimator designed for CZT gamma-camera compared to a conventional sodium iodide (NaI) (Tl) gamma-camera. Post-therapeutic 177Lu-DOTATATE imaging on a CZT device with a medium energy high resolution (MEHRS)-collimator are promising and support the widespread of both 177Lu-based peptide-receptor radionuclide therapy (PRRT) and CZT gamma-cameras.PMID:34352056 | DOI:10.1967/s002449912361 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Emmanuel Deshayes Cyril Fersing K évin Hébert Manuel Bardies Pierre Olivier Kotzki Lore Santoro Source Type: research

Accuracy of hepatobiliary scintigraphy and added value of SPECT/CT versus planar imaging for diagnosing biliary atresia
Hell J Nucl Med. 2021 May-Aug;24(2):108-113. doi: 10.1967/s002449912350. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Hepatobiliary scintigraphy (HBS) is an important tool in diagnosing biliary atresia in infants. There is limited evidence on the use of single photon emission computed tomography/computed tomography (SPECT/CT) as an additional imaging method to planar imaging. We evaluated the value of SPECT/CT in unclear cases of planar HBS.SUBJECTS AND METHODS: Consecutive patients with suspected biliary atresia who underwent guideline-compliant HBS from January 2010 until March 2020 were reviewed, and cases with SPECT/CT were iden...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Trine Borup Andersen Ramune Aleksyniene Lars Borup Petersen Source Type: research

Myocardial perfusion SPECT as a potential mediator on circulating chromogranin A in patients with old myocardial infarction
Hell J Nucl Med. 2021 May-Aug;24(2):114-121. doi: 10.1967/s002449912351. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Chromogranin A (CgA) is a soluble polypeptide stored within and released from secretory granules of endocrine and other cell types (including cardiomyocytes); CgA appears to be a marker of the overall neuroendocrine activity. Increased levels of serum CgA have been found not only in patients with neuroendocrine neoplasms but also with other malignancies, hypertension, myocardial infarction, heart, or renal failure.SUBJECTS AND METHODS: A population of 307 patients (202 males, 105 females) was enrolled. The study grou...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Xanthi Xourgia Spyridon Tsiouris Theofilos Kolettis Ioannis Goudevenos Angelos Arseniou Andreas D Fotopoulos Source Type: research

Is SUVmax a useful marker for progression-free survival in patients with metastatic GEP-NET receiving < sup > 177 < /sup > Lu-DOTATATE therapy?
CONCLUSION: The pre-treatment SUVmax values of 68Ga-DOTATATE PET/CT in lesions are a potential prognostic factor for PFS in well-differentiated gastroenteropancreatic neuroendocrine tumors undergoing 177Lu-DOTATATE treatment, and could be a useful parameter for the treatment selection.PMID:34352047 | DOI:10.1967/s002449912352 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Fatih Teker Umut Elboga Source Type: research

< sup > 18 < /sup > F-FDG PET/CT for assessing of disease activity of idiopathic inflammatory myopathies. A systematic review and meta-analysis
CONCLUSION: Fluorine-18-FDG PET/CT has a good performance for the detection of active disease status in patients with IM. Although there are no guidelines for adopting imaging techniques, more objective and updated criteria for the assessment of disease activity incorporated with 18F-FDG PET/CT should be introduced and validated. Further studies are necessary to determine if 18F-FDG PET/CT-based treatment of IM can improve outcomes.PMID:34352048 | DOI:10.1967/s002449912353 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Keunyoung Kim Seong Jang Kim Source Type: research

Pancreatic metastasis from papillary thyroid carcinoma: Case report and literature review
Hell J Nucl Med. 2021 May-Aug;24(2):140-148. doi: 10.1967/s002449912354. Epub 2021 Aug 6.ABSTRACTPapillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy. Papillary thyroid carcinoma generally spreads locally to the cervical lymph nodes, but distant metastases are seen in 5%-7% of cases. Most distant metastases occur in the bone, lung, and brain. Pancreatic metastases of PTC are extremely rare. Herein we present a patient with PTC treated with total thyroidectomy and two rounds of radioactive iodine (RAI) ablation that was subsequently found to have a pancreaticmetastasis detected on fluorine-18-fluo...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Rachel Stein Taylor S Harmon Caitlin E Harmon Enoch Kuo Savas Ozdemir Source Type: research

MRI and < sup > 18 < /sup > F-FDG PET/CT findings of a giant cell tumor of the tendon sheath of the knee joint (pigmented villonodular synovitis): A case report and literature review
We present a case of a 33-year-old female hospitalized with a 3-month history of right knee pain when squatting. Her physical examination showed no resting pain or local skin fever. Magnetic resonance imaging (MRI) showed multiple nodular long T1 and short T2 abnormal signal shadows in the popliteal fossa region. A patchy T2 high signal shadow was found in the soft tissue around the right knee.Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed multiple soft tissue density nodules around and within the right knee joint (largest 20x13mm) with a maximum standardized uptak...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Xue Liu Huaiwei Xu Tao Jiang Bao Zhang Youcheng Li Wenbing Zeng Source Type: research

Heterogeneous radioiodine uptake in breast fibroadenoma: A case report
Hell J Nucl Med. 2021 May-Aug;24(2):155-156. doi: 10.1967/s002449912356. Epub 2021 Aug 6.NO ABSTRACTPMID:34352051 | DOI:10.1967/s002449912356 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Lingzhi Cao Fanhui Yang Wanxing Gou Jianping Xie Source Type: research

Thymic MALT lymphoma mimicking parathyroid adenoma uptake on < sup > 99m < /sup > Tc-MIBI parathyroid scintigraphy
Hell J Nucl Med. 2021 May-Aug;24(2):157-158. doi: 10.1967/s002449912357. Epub 2021 Aug 6.NO ABSTRACTPMID:34352052 | DOI:10.1967/s002449912357 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Fanhui Yang Zongxi He Lingzhi Cao Jianping Xie Source Type: research

HER-2 breast cancer treatment induced mediastinal sarcoid like reaction depicted on < sup > 18 < /sup > F-FDG PET/CT
Hell J Nucl Med. 2021 May-Aug;24(2):159-160. doi: 10.1967/s002449912358. Epub 2021 Aug 6.ABSTRACTThis is a case of a woman with breast cancer, who developed mediastinal sarcoid-like reaction, depicted on PET/CT, which was histologically confirmed, following treatment with trastuzumab and pertuzumab. The development of noncaseating granulomas in patients who do not fulfill the criteria for systemic sarcoidosis is known as sarcoid-like reaction, having been described in association with trastuzumab in a few case reports, but none with pertuzumab. Physicians should be aware of the potentially higher rate of sarcoid-like react...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Emmanouil Panagiotidis Anna Paschali Anna Andreadou Vassiliki Chatzipavlidou Source Type: research

Unusual unilateral renal mass with pulmonary multiple nodules as the initial presentation of granulomatosis with polyangiitis
We report a case of a 32-year-old man with recurrent fever, cough and left lumbago for more than one month. Computed tomography (CT) and magnetic resonance imaging (MRI) found bilateral multiple pulmonary nodules and a tumor-like mass in the left kidney. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed increased uptake in the right pharyngeal recess along with pulmonary and renal hypermetabolic lesions. The pathologic findings of pulmonary and renal specimens were suggestive of granulomatous inflammatory changes. Further laboratory examinations showed an elevated lev...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Hongyuan Dai Fanglan Li Rui Huang Source Type: research

Primary diffuse large B-cell lymphoma of seminal vesicles detected by < sup > 18 < /sup > F-FDG PET/CT
Hell J Nucl Med. 2021 May-Aug;24(2):163-164. doi: 10.1967/s002449912360. Epub 2021 Aug 6.NO ABSTRACTPMID:34352055 | DOI:10.1967/s002449912360 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Weidong Gong Xiao Yang Junhao Wu Lei Ou Chunyin Zhang Source Type: research

Whole body planar and 3D quantitative imaging after < sup > 177 < /sup > Lu-DOTATATE on CZT SPECT/CT device with MEHRS collimator. First report
We present here in the first reported images acquired with a new collimator designed for CZT gamma-camera compared to a conventional sodium iodide (NaI) (Tl) gamma-camera. Post-therapeutic 177Lu-DOTATATE imaging on a CZT device with a medium energy high resolution (MEHRS)-collimator are promising and support the widespread of both 177Lu-based peptide-receptor radionuclide therapy (PRRT) and CZT gamma-cameras.PMID:34352056 | DOI:10.1967/s002449912361 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Emmanuel Deshayes Cyril Fersing K évin Hébert Manuel Bardies Pierre Olivier Kotzki Lore Santoro Source Type: research

Accuracy of hepatobiliary scintigraphy and added value of SPECT/CT versus planar imaging for diagnosing biliary atresia
Hell J Nucl Med. 2021 May-Aug;24(2):108-113. doi: 10.1967/s002449912350. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Hepatobiliary scintigraphy (HBS) is an important tool in diagnosing biliary atresia in infants. There is limited evidence on the use of single photon emission computed tomography/computed tomography (SPECT/CT) as an additional imaging method to planar imaging. We evaluated the value of SPECT/CT in unclear cases of planar HBS.SUBJECTS AND METHODS: Consecutive patients with suspected biliary atresia who underwent guideline-compliant HBS from January 2010 until March 2020 were reviewed, and cases with SPECT/CT were iden...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Trine Borup Andersen Ramune Aleksyniene Lars Borup Petersen Source Type: research

Myocardial perfusion SPECT as a potential mediator on circulating chromogranin A in patients with old myocardial infarction
Hell J Nucl Med. 2021 May-Aug;24(2):114-121. doi: 10.1967/s002449912351. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Chromogranin A (CgA) is a soluble polypeptide stored within and released from secretory granules of endocrine and other cell types (including cardiomyocytes); CgA appears to be a marker of the overall neuroendocrine activity. Increased levels of serum CgA have been found not only in patients with neuroendocrine neoplasms but also with other malignancies, hypertension, myocardial infarction, heart, or renal failure.SUBJECTS AND METHODS: A population of 307 patients (202 males, 105 females) was enrolled. The study grou...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Xanthi Xourgia Spyridon Tsiouris Theofilos Kolettis Ioannis Goudevenos Angelos Arseniou Andreas D Fotopoulos Source Type: research

Is SUVmax a useful marker for progression-free survival in patients with metastatic GEP-NET receiving < sup > 177 < /sup > Lu-DOTATATE therapy?
CONCLUSION: The pre-treatment SUVmax values of 68Ga-DOTATATE PET/CT in lesions are a potential prognostic factor for PFS in well-differentiated gastroenteropancreatic neuroendocrine tumors undergoing 177Lu-DOTATATE treatment, and could be a useful parameter for the treatment selection.PMID:34352047 | DOI:10.1967/s002449912352 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Fatih Teker Umut Elboga Source Type: research

< sup > 18 < /sup > F-FDG PET/CT for assessing of disease activity of idiopathic inflammatory myopathies. A systematic review and meta-analysis
CONCLUSION: Fluorine-18-FDG PET/CT has a good performance for the detection of active disease status in patients with IM. Although there are no guidelines for adopting imaging techniques, more objective and updated criteria for the assessment of disease activity incorporated with 18F-FDG PET/CT should be introduced and validated. Further studies are necessary to determine if 18F-FDG PET/CT-based treatment of IM can improve outcomes.PMID:34352048 | DOI:10.1967/s002449912353 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Keunyoung Kim Seong Jang Kim Source Type: research

Pancreatic metastasis from papillary thyroid carcinoma: Case report and literature review
Hell J Nucl Med. 2021 May-Aug;24(2):140-148. doi: 10.1967/s002449912354. Epub 2021 Aug 6.ABSTRACTPapillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy. Papillary thyroid carcinoma generally spreads locally to the cervical lymph nodes, but distant metastases are seen in 5%-7% of cases. Most distant metastases occur in the bone, lung, and brain. Pancreatic metastases of PTC are extremely rare. Herein we present a patient with PTC treated with total thyroidectomy and two rounds of radioactive iodine (RAI) ablation that was subsequently found to have a pancreaticmetastasis detected on fluorine-18-fluo...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Rachel Stein Taylor S Harmon Caitlin E Harmon Enoch Kuo Savas Ozdemir Source Type: research

MRI and < sup > 18 < /sup > F-FDG PET/CT findings of a giant cell tumor of the tendon sheath of the knee joint (pigmented villonodular synovitis): A case report and literature review
We present a case of a 33-year-old female hospitalized with a 3-month history of right knee pain when squatting. Her physical examination showed no resting pain or local skin fever. Magnetic resonance imaging (MRI) showed multiple nodular long T1 and short T2 abnormal signal shadows in the popliteal fossa region. A patchy T2 high signal shadow was found in the soft tissue around the right knee.Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed multiple soft tissue density nodules around and within the right knee joint (largest 20x13mm) with a maximum standardized uptak...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Xue Liu Huaiwei Xu Tao Jiang Bao Zhang Youcheng Li Wenbing Zeng Source Type: research

Heterogeneous radioiodine uptake in breast fibroadenoma: A case report
Hell J Nucl Med. 2021 May-Aug;24(2):155-156. doi: 10.1967/s002449912356. Epub 2021 Aug 6.NO ABSTRACTPMID:34352051 | DOI:10.1967/s002449912356 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Lingzhi Cao Fanhui Yang Wanxing Gou Jianping Xie Source Type: research

Thymic MALT lymphoma mimicking parathyroid adenoma uptake on < sup > 99m < /sup > Tc-MIBI parathyroid scintigraphy
Hell J Nucl Med. 2021 May-Aug;24(2):157-158. doi: 10.1967/s002449912357. Epub 2021 Aug 6.NO ABSTRACTPMID:34352052 | DOI:10.1967/s002449912357 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Fanhui Yang Zongxi He Lingzhi Cao Jianping Xie Source Type: research

HER-2 breast cancer treatment induced mediastinal sarcoid like reaction depicted on < sup > 18 < /sup > F-FDG PET/CT
Hell J Nucl Med. 2021 May-Aug;24(2):159-160. doi: 10.1967/s002449912358. Epub 2021 Aug 6.ABSTRACTThis is a case of a woman with breast cancer, who developed mediastinal sarcoid-like reaction, depicted on PET/CT, which was histologically confirmed, following treatment with trastuzumab and pertuzumab. The development of noncaseating granulomas in patients who do not fulfill the criteria for systemic sarcoidosis is known as sarcoid-like reaction, having been described in association with trastuzumab in a few case reports, but none with pertuzumab. Physicians should be aware of the potentially higher rate of sarcoid-like react...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Emmanouil Panagiotidis Anna Paschali Anna Andreadou Vassiliki Chatzipavlidou Source Type: research

Unusual unilateral renal mass with pulmonary multiple nodules as the initial presentation of granulomatosis with polyangiitis
We report a case of a 32-year-old man with recurrent fever, cough and left lumbago for more than one month. Computed tomography (CT) and magnetic resonance imaging (MRI) found bilateral multiple pulmonary nodules and a tumor-like mass in the left kidney. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed increased uptake in the right pharyngeal recess along with pulmonary and renal hypermetabolic lesions. The pathologic findings of pulmonary and renal specimens were suggestive of granulomatous inflammatory changes. Further laboratory examinations showed an elevated lev...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Hongyuan Dai Fanglan Li Rui Huang Source Type: research

Primary diffuse large B-cell lymphoma of seminal vesicles detected by < sup > 18 < /sup > F-FDG PET/CT
Hell J Nucl Med. 2021 May-Aug;24(2):163-164. doi: 10.1967/s002449912360. Epub 2021 Aug 6.NO ABSTRACTPMID:34352055 | DOI:10.1967/s002449912360 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Weidong Gong Xiao Yang Junhao Wu Lei Ou Chunyin Zhang Source Type: research

Whole body planar and 3D quantitative imaging after < sup > 177 < /sup > Lu-DOTATATE on CZT SPECT/CT device with MEHRS collimator. First report
We present here in the first reported images acquired with a new collimator designed for CZT gamma-camera compared to a conventional sodium iodide (NaI) (Tl) gamma-camera. Post-therapeutic 177Lu-DOTATATE imaging on a CZT device with a medium energy high resolution (MEHRS)-collimator are promising and support the widespread of both 177Lu-based peptide-receptor radionuclide therapy (PRRT) and CZT gamma-cameras.PMID:34352056 | DOI:10.1967/s002449912361 (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Emmanuel Deshayes Cyril Fersing K évin Hébert Manuel Bardies Pierre Olivier Kotzki Lore Santoro Source Type: research

Accuracy of hepatobiliary scintigraphy and added value of SPECT/CT versus planar imaging for diagnosing biliary atresia
Hell J Nucl Med. 2021 May-Aug;24(2):108-113. doi: 10.1967/s002449912350. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Hepatobiliary scintigraphy (HBS) is an important tool in diagnosing biliary atresia in infants. There is limited evidence on the use of single photon emission computed tomography/computed tomography (SPECT/CT) as an additional imaging method to planar imaging. We evaluated the value of SPECT/CT in unclear cases of planar HBS.SUBJECTS AND METHODS: Consecutive patients with suspected biliary atresia who underwent guideline-compliant HBS from January 2010 until March 2020 were reviewed, and cases with SPECT/CT were iden...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Trine Borup Andersen Ramune Aleksyniene Lars Borup Petersen Source Type: research

Myocardial perfusion SPECT as a potential mediator on circulating chromogranin A in patients with old myocardial infarction
Hell J Nucl Med. 2021 May-Aug;24(2):114-121. doi: 10.1967/s002449912351. Epub 2021 Aug 6.ABSTRACTOBJECTIVE: Chromogranin A (CgA) is a soluble polypeptide stored within and released from secretory granules of endocrine and other cell types (including cardiomyocytes); CgA appears to be a marker of the overall neuroendocrine activity. Increased levels of serum CgA have been found not only in patients with neuroendocrine neoplasms but also with other malignancies, hypertension, myocardial infarction, heart, or renal failure.SUBJECTS AND METHODS: A population of 307 patients (202 males, 105 females) was enrolled. The study grou...
Source: Hellenic Journal of Nuclear Medicine - August 5, 2021 Category: Nuclear Medicine Authors: Xanthi Xourgia Spyridon Tsiouris Theofilos Kolettis Ioannis Goudevenos Angelos Arseniou Andreas D Fotopoulos Source Type: research