Harmonized pretreatment quantitative volume-based 18F-FDG PET/CT parameters for stage IV breast cancer prognosis. Multicenter study in Japan.
CONCLUSION: In metastatic breast cancer patients, harmonized pretreatment quantitative volume-based 18F-FDG PET/CT parameters, especially whole-body TLG, are potential surrogate markers for prognosis. PMID: 33367302 [PubMed - in process] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Is 177Lu-PSMA an effective treatment modality for mCRPC patients with bone and visceral metastasis?
CONCLUSION: Lutetium-177-PSMA was a reasonable palliative treatment option with limited toxicity for these end-stage mCRPC patients with visceral metastasis with adequate PSA stabilization. A synergistic drug amalgamation may be an ideal way to boost the outcome in the future. PMID: 33367303 [PubMed - in process] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The role of 68Ga-DOTATATE PET/CT and 18F-FDG PET/CT in the follow-up of patients with medullary thyroid cancer.
CONCLUSION: Both 18F-FDG PET/CT and 68Ga-DOTATATE PET/CT are efficient imaging modalities in detection of recurrent or metastatic disease in MTC patients. Gallium-68-DOTATATE PET/CT could be more beneficial in detection of bone metastases with respect to 18F-FDG PET/CT. PMID: 33367304 [PubMed - in process] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Optimization of scatter estimation window setting for quantitative analysis in 111 In-pentetreotide single photon emission computed tomography imaging.
CONCLUSION: The scatter correction method that gave optimal image quality and quantitative accuracy was MEW3 with two 20% energy windows (one over each photopeak) and four adjacent 3% scatter estimation windows (one on each side of the two photopeaks). PMID: 33306751 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Factors affecting overall survival and progression-free survival in patients with metastatic castration resistant prostate cancer received 177Lu PSMA I & T therapy.
Factors affecting overall survival and progression-free survival in patients with metastatic castration resistant prostate cancer received 177Lu PSMA I&T therapy. Hell J Nucl Med. 2020 Dec 14;: Authors: Bülbül O, Ünek İT, Kefi A, Tuna EB, Bekiş R Abstract OBJECTIVE: Lutetium-177 (177Lu) prostate specific membrane antigen (PSMA) radionuclide therapy (RNT) is an effective and safe treatment option in patients with metastatic castration resistant prostate cancer (mCRPC). The first aim of this study was to determine RNT response rate. The second and main aim of this study is measure ov...
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The frequency of thyroid incidental findings and risk of malignancy detected by 68Ga-labeled prostate-specific membrane antigen PET/CT in prostate cancer.
CONCLUSION: Gallium-68-PSMA thyroid incidental findings are rare in prostate cancer patients. However, cases of focal PSMA uptake in the thyroid gland should be further investigated, as these findings may represent metastatic or primary malignancy of the thyroid gland. PMID: 33306753 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Initial activity-related long-term outcome of iodine-131 treatment for thyroidectomy patients with differentiated thyroid carcinoma.
CONCLUSION: For patients with specific thyroidectomy for differentiated thyroid cancer, a high initial regimen of 131I treatment is more effective than the low activity regimen. An increased activity of the initial 131I regimen significantly reduced the total treatment number and medical expenditure. PMID: 33306754 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The use of focused, radioguided parathyroidectomy in geriatric patients with a history of thyroid surgery.
CONCLUSION: Radioguidance parathyroidectomy positively affected the operative time and also decreased the need for additional frozen section. PMID: 33306755 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The effect of preoperative 18F-FDG PET on the surgical decision in early breast cancer: 5-Year follow-up.
CONCLUSION: We observed that we could not achieve a significant difference in 5-year metastasis/recurrence between the groups. Moreover, due to 18F-FDG-PET high false positivity, it significantly extended the time to surgery (P-value 0.01). In early-stage BC, 18F-FDG PET demonstrated better performance in axillary lymph nodes metastases detection in comparison with other diagnostic imaging methods, even if SLNB remains the gold standard technique. PMID: 33306756 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Is whole body low dose CT still necessary in the era of 18F-FDG PET/CT for the assessment of bone disease in multiple myeloma patients?
CONCLUSION: Low dose computed tomography co-registered PET has comparable performance to WBLDCT. If confirmed on a lager sample, these encouraging results suggest the possibility to use this multimodal hybrid imaging as the only method for MM evaluation, rather than both exams, providing both morphologic and metabolic information in one session with impact on patient compliance, health care spending and especially radiation exposure. PMID: 33306757 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Predictive value of PET/CT based metabolic information in the modern 3D based radiotherapy treatment of head and neck can-cer patients - single institute study.
CONCLUSION: Simple metabolic data (SUVmax and SULpeak) from pretreatment fluorine-18-fluorodeoxyglucose (18F-FDG) PET/CT were unable to predict therapeutic response, while volumetric information containing MTV and TLG parameters proved to be more useful, thus their inclusion to risk stratification may also have additional value. PMID: 33306758 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

68Ga-citrate positron emission tomography/computed tomography findings in an experimental model of acute appendicitis in rabbits.
CONCLUSION: Acute appendicitis is accurately imaged in an experimental rabbit model by using 68Ga-citrate with PET/CT. PMID: 33306759 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The efficiency of hybrid perfusion SPECT/CT imaging in the diagnostic strategy of pulmonary thromboembolism.
This study aimed to evaluate the effectiveness of hybrid perfusion SPECT with a low dose CT method in the diagnostic strategy of PTE. MATERIAL AND METHODS: Two physicians reviewed 305 patients' data for this retrospective study. All patients had Q SPECT/CT data as initial imaging, and Ventilation SPECT was added to the selected patients' algorithm. The diagnostic performance and inter-observer agreement were determined for both Q SPECT and Q SPECT/CT methods. The final diagnosis was made by clinical decision with all tests and follow-up for at least 6-month. RESULTS: The majority (92%) of our study group were corre...
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

90Y-microsphere radioembolization: The method, clinical evidence and perspective.
Authors: Spyridonidis T, Papathanasiou N, Spyridonidis J, Ntzoumani C, Spyropoulou D, Katsanos K, Apostolopoulos DJ Abstract The current review unfolds the procedural steps and the clinical evidence for yttrium-90 (90Y)-microspheres radioembolization. Radioembolization is part of the loco-regional therapeutic spectrum for liver malignancy and involves the invasive, intra-arterial delivery of microspheres carrying β-emitter isotopes in order to destroy cancerous tissue via ionizing radiation. The main steps of the therapeutic process are selection of eligible patients, angiographic workup, simulation scintigrap...
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

PET/CT imaging of prostate cancer in the era of small molecule prostate specific membrane antigen targeted tracers.
Authors: Vrachimis A, Ferentinos K, Demetriou E, Ioannides C, Zamboglou N Abstract Staging and restaging of prostate cancer is crucial for treatment planning and prognosis. Accurate localization is of high relevance for a tailor-made therapy and an early detection of unknown metastatic spread can lead to a survival benefit. Evidence based guidelines that are currently in use were established using data from conventional imaging (such as magnetic resonance imaging (MRI), computed tomography (CT) and bone scintigraphy). Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) is rapidly evolving w...
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

A rare case of multiple primary extragastrointestinal stromal tumors in the abdominopelvic cavity detected by 18F-FDG PET/CT.
Authors: Xiao JX, Ye J, Huang SS, Guo CM, Su M, Wang D Abstract An extragastrointestinal stromal tumor (EGIST) refers to the gastrointestinal stromal tumor in any location outside the gastrointestinal tract originates from mesenchymal tumors. The majority of the EGIST appeared as isolated mass, and multiple primary EGIST is quite rare. Here, we report a 36-year-old man of multiple EGIST in the abdominopelvic cavity, which was misdiagnosed as lymphoma on fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging. The patient received adjuvant drug treatment (imatinib, 40...
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

How COVID-19 pandemic affected cancer progression: Three different scenarios evidenced by PET imaging.
Authors: Mileva M, Artigas C, Gebhart G, Flamen P, Karfis I Abstract COVID-19 pandemic is having a strong impact on healthcare providers around the world, by refocusing and reducing non-essential medical activities. Nuclear medicine departments among others, have been reorganizing and reprioritizing diagnostic and theragnostic procedures. This reorganizing had a negative impact on the supply of positron emission tomography (PET) services to oncologic patients, whose health was affected. We herein present the PET findings in three different cancer scenarios in which disease course was dramatically affected by the CO...
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Mesenteric desmoid tumors masquerading as peritoneal carcinomatosis.
Authors: Choi WH, Han EJ PMID: 33306765 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

18F-FDG PET/CT imaging in a patient with solitary primary sacral lymphoma.
We report a case of a 77-year-old male patient who presented with unexplained numbness and pain in the right lower extremity for over 2 months. Tumor markers and other laboratory were unremarkable. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed a solitary osteolytic bone lesion of the sacrum with intense 18F-FDG uptake (SUVmax=10.7). The subsequent biopsy confirmed the diagnosis of diffuse large B-cell lymphoma. After one cycle of R-CHOP, the neurological symptoms of the patient improved significantly. PMID: 33306766 [PubMed - as supplied by publisher] (Source:...
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

18F-FDG PET/CT imaging for a solitary primary bone lymphoma of the maxilla.
We describe a case of fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging revealed solitary osseous lytic lesion with intense uptake in the maxilla, suggesting a primary skeletal malignancy. The subsequent histopathologic examination confirmed the diagnosis of high-grade B-cell lymphoma (HGBL). PMID: 33306767 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

A low-grade bone angiosarcoma presented as low to mild 18F-FDG uptake mimicking multiple myeloma.
We report a rare case of multicentric bone angiosarcoma in a 51-year-old female patient showing low to mild 18F-FDG uptake, mimicking multiple myeloma, which often presents mild 18F-FDG avid lesions. PMID: 33306768 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - December 13, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The modifications brought about by the COVID-19 pandemic to Nuclear Medicine practice.
Authors: Chatzipavlidou V Abstract Nearly 19.9 million cases and more than 730 thousand disease-related deaths have been confirmed in the months that followed WHO's assessment that the novel coronavirus COVID-19, first emerged in Wuhan China on December 2019, could be characterized as a pandemic. The aforementioned coronavirus affected 188 countries as of 8.10.2020. Despite the continually increasing number of COVID-19 cases reported to CDC, at national level, the percentage of visits to outpatient providers and emergency departments has decreased and mortality rates attributed to COVID-19 have declined compared to...
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

SARS-CoV2: Diagnostic tests available to the clinician.
Authors: Hadweh P, Orfanidou T, Tsiamita M, Timologos G, Papadopoulos T Abstract On December 2019, a new coronavirus disease (COVID-19) emerged in China and spread worldwide, causing acute severe respiratory syndrome. Due to the increased transmission rate of the virus, it became of great importance the early diagnosis of the disease. The coronavirus pandemic led to the development of numerous tests in order to mass screening population for active viral load and for the identification of antibodies for epidemiological purposes. This review summarizes the different diagnostic tests available to the clinicians for th...
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The consequences of COVID-19 pandemic in the routine of Nuclear Medicine Departments.
Authors: Papanastasiou E Abstract The outbreak and spreading of the COVID-19 pandemic have affected billions of people around the world, severely disrupting many aspects of their lives. Although not at the frontline of the pandemic response, Nuclear Medicine departments have to adopt their clinical routine to the new environment. A series of protective measures, including among others spatial arrangements to promote social distancing, meticulous hand hygiene and use of personal protective equipment, workload reduction, patient screening at admission and examination protocol adjustments, have to be adopted in order ...
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Challenges and priorities in skeletal, gastrointestinal, hepatobiliary, genitourinary and lung scintigraphy during the COVID-19 pandemic.
Authors: Koutsikos J, Angelidis G Abstract On December 29, 2019, a hospital in the City of Wuhan, Hubei Province, in Central China, admitted four individuals with pneumonia. The hospital reported this occurrence to the local center for disease control (CDC), which lead Wuhan CDC staff to initiate a field investigation with a retrospective search for pneumonia patients. On December 31, 2019, the World Health Organization (WHO) was alerted by the Chinese authorities for several cases of pneumonia of unknown origin in the City of Wuhan. On January 7, 2020, a novel virus was identified as the causative agent, belonging...
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Nuclear Cardiology practice in COVID-19 era.
Authors: Paschali A, Anagnostopoulos C Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is the biggest shock in decades to the well developed healthcare system and resources worldwide. Although there was a wide variation in the level of preparedness, the transition was tough even for the most renowned healthcare systems. Increasing the capacity and adapting healthcare for the needs of COVID-19 patients is described by the WHO as a fundamental outbreak response measure. However, while the system is preoccupied with a pandemic infection, patients suffering from other illnesses are in high risk to get infecte...
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

COVID-19 pandemic: Implications for radionuclide therapy in Nuclear Medicine departments.
Authors: Koukouraki S, Kapsoritakis N, Bourogianni O Abstract The global COVID-19 health and economic crisis has forced people to adopt challenging rules of social distancing and self-isolation. Health care staff has been advised to change working routines to keep themselves and their patients safe. Radionuclide therapy has had an increasing role in clinical practice. Most therapeutic radionuclide procedures have applications in oncology. Cancer patients are an especially fragile and vulnerable population with higher risk due to co morbidities and immunosuppression. COVID-19 is another risk that must be considered ...
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Nuclear Medicine and Oncology in the COVID-19 pandemic era.
Authors: Panagiotidis E Abstract The coronavirus disease 2019 (COVID-19) global pandemic poses a significant challenge to the national health systems. Not only China, the first country that experienced the health crisis since last December, but the rest of the world, is facing an unprecedented global health crisis, the most serious crisis in a century, with social and economic impact. However, the most important impact of the new pandemic is the human impact. Till 4th of June 2020, coronavirus SARS-CoV-2, causing COVID-19 disease, has infected more than 65000.000 people and has been responsible for more than 386000...
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Nuclear thyroidology in pandemic times: The paradigm shift of COVID-19.
The objective of the current paper is to provide guidance on how diagnostic and therapeutic management of patients with thyroid diseases can be safely and effectively adjusted during pandemic, in nuclear medicine settings. PMID: 32862214 [PubMed - in process] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Non-Oncological PET/CT imaging during SARS-CoV-2 pandemic.
Authors: Exadaktylou P, Papadopoulos N, Chatzipavlidou V, Giammarile F Abstract In December 2019 a new β-CoV, Severe Acute Respiratory Coronavirus- 2 (SARS-CoV-2), has been identified in Wuhan Hubei Province, China. Within a few months it spread rapidly to more than 114 countries and the disease, Coronavirus disease 2019 (COVID-19), was declared pandemic on 11th February 2020 by the World Health Organization (WHO). Until 20 June 2020 8:09 am, 8,465,085 cases of COVID-19 were confirmed globally, with 454,258 deaths. The first incidence in Greece was documented on 26 February 2020 in Thessaloniki and up to 20 Ju...
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Recommendations for nuclear neuroimaging of patients with neurological disorders in the COVID-19 era.
Authors: Valotassiou V, Angelidis G, Georgoulias P Abstract The novel coronavirus disease 2019 (COVID-19) pandemic has changed people's normal lives in a very short time causing extensive infections and mortality, which required the national health systems to be adapted to new situation. Changes in healthcare services included modifications of standard procedures in nuclear medicine departments in order to limit COVID-19 spreading and protect patients and personnel. Here, we recommend management of patients with neurological diseases and especially dementia and movement disorders, who are referred for neuroimaging ...
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

COVID-19 and cancer: Revisiting "The comfort zone".
COVID-19 and cancer: Revisiting "The comfort zone". Hell J Nucl Med. 2020 May-Aug;23 Suppl:65-69 Authors: Retsas S PMID: 32862217 [PubMed - in process] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - September 1, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The modifications brought about by the COVID-19 pandemic to Nuclear Medicine practice.
Authors: Chatzipavlidou V Abstract Nearly 19.9 million cases and more than 730 thousand disease-related deaths have been confirmed in the months that followed WHO's assessment that the novel coronavirus COVID-19, first emerged in Wuhan China on December 2019, could be characterized as a pandemic. The aforementioned coronavirus affected 188 countries as of 8.10.2020. Despite the continually increasing number of COVID-19 cases reported to CDC, at national level, the percentage of visits to outpatient providers and emergency departments has decreased and mortality rates attributed to COVID-19 have declined compared to...
Source: Hellenic Journal of Nuclear Medicine - August 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

SARS-CoV2: Diagnostic tests available to the clinician.
Authors: Hadweh P, Orfanidou T, Tsiamita M, Timologos G, Papadopoulos T Abstract On December 2019, a new coronavirus disease (COVID-19) emerged in China and spread worldwide, causing acute severe respiratory syndrome. Due to the increased transmission rate of the virus, it became of great importance the early diagnosis of the disease. The coronavirus pandemic led to the development of numerous tests in order to mass screening population for active viral load and for the identification of antibodies for epidemiological purposes. This review summarizes the different diagnostic tests available to the clinicians for th...
Source: Hellenic Journal of Nuclear Medicine - August 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The consequences of COVID-19 pandemic in the routine of Nuclear Medicine Departments.
Authors: Papanastasiou E Abstract The outbreak and spreading of the COVID-19 pandemic have affected billions of people around the world, severely disrupting many aspects of their lives. Although not at the frontline of the pandemic response, Nuclear Medicine departments have to adopt their clinical routine to the new environment. A series of protective measures, including among others spatial arrangements to promote social distancing, meticulous hand hygiene and use of personal protective equipment, workload reduction, patient screening at admission and examination protocol adjustments, have to be adopted in order ...
Source: Hellenic Journal of Nuclear Medicine - August 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Challenges and priorities in skeletal, gastrointestinal, hepatobiliary, genitourinary and lung scintigraphy during the COVID-19 pandemic.
Authors: Koutsikos J, Angelidis G Abstract On December 29, 2019, a hospital in the City of Wuhan, Hubei Province, in Central China, admitted four individuals with pneumonia. The hospital reported this occurrence to the local center for disease control (CDC), which lead Wuhan CDC staff to initiate a field investigation with a retrospective search for pneumonia patients. On December 31, 2019, the World Health Organization (WHO) was alerted by the Chinese authorities for several cases of pneumonia of unknown origin in the City of Wuhan. On January 7, 2020, a novel virus was identified as the causative agent, belonging...
Source: Hellenic Journal of Nuclear Medicine - August 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Nuclear Cardiology practice in COVID-19 era.
Authors: Paschali A, Anagnostopoulos C Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is the biggest shock in decades to the well developed healthcare system and resources worldwide. Although there was a wide variation in the level of preparedness, the transition was tough even for the most renowned healthcare systems. Increasing the capacity and adapting healthcare for the needs of COVID-19 patients is described by the WHO as a fundamental outbreak response measure. However, while the system is preoccupied with a pandemic infection, patients suffering from other illnesses are in high risk to get infecte...
Source: Hellenic Journal of Nuclear Medicine - August 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

COVID-19 pandemic: Implications for radionuclide therapy in Nuclear Medicine departments.
Authors: Koukouraki S, Kapsoritakis N, Bourogianni O Abstract The global COVID-19 health and economic crisis has forced people to adopt challenging rules of social distancing and self-isolation. Health care staff has been advised to change working routines to keep themselves and their patients safe. Radionuclide therapy has had an increasing role in clinical practice. Most therapeutic radionuclide procedures have applications in oncology. Cancer patients are an especially fragile and vulnerable population with higher risk due to co morbidities and immunosuppression. COVID-19 is another risk that must be considered ...
Source: Hellenic Journal of Nuclear Medicine - August 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Nuclear Medicine and Oncology in the COVID-19 pandemic era.
Authors: Panagiotidis E Abstract The coronavirus disease 2019 (COVID-19) global pandemic poses a significant challenge to the national health systems. Not only China, the first country that experienced the health crisis since last December, but the rest of the world, is facing an unprecedented global health crisis, the most serious crisis in a century, with social and economic impact. However, the most important impact of the new pandemic is the human impact. Till 4th of June 2020, coronavirus SARS-CoV-2, causing COVID-19 disease, has infected more than 65000.000 people and has been responsible for more than 386000...
Source: Hellenic Journal of Nuclear Medicine - August 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Nuclear thyroidology in pandemic times: The paradigm shift of COVID-19.
The objective of the current paper is to provide guidance on how diagnostic and therapeutic management of patients with thyroid diseases can be safely and effectively adjusted during pandemic, in nuclear medicine settings. PMID: 32860396 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Non-Oncological PET/CT imaging during SARS-CoV-2 pandemic.
Authors: Exadaktylou P, Papadopoulos N, Chatzipavlidou V, Giammarile F Abstract In December 2019 a new β-CoV, Severe Acute Respiratory Coronavirus- 2 (SARS-CoV-2), has been identified in Wuhan Hubei Province, China. Within a few months it spread rapidly to more than 114 countries and the disease, Coronavirus disease 2019 (COVID-19), was declared pandemic on 11th February 2020 by the World Health Organization (WHO). Until 20 June 2020 8:09 am, 8,465,085 cases of COVID-19 were confirmed globally, with 454,258 deaths. The first incidence in Greece was documented on 26 February 2020 in Thessaloniki and up to 20 Ju...
Source: Hellenic Journal of Nuclear Medicine - August 30, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Absorbed dose estimation to cohabitants and co-travelers of patients treated with radioiodine for differentiated thyroid carcinoma.
CONCLUSION: Provided necessary precautions are followed, radiation burden to the family members and co-travelers of DTC patients treated with radioiodine following thyroidectomy can be kept well below the corresponding dose limits and constraints. PMID: 32830204 [PubMed - in process] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - August 26, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

99mTc-MAA total body imaging of patent right-to-left shunt with invisible brain activity.
Authors: Son HJ, Ryu JS Abstract Generally, the presence of brain activity in technetium-99m macro aggregated albumin (99mTc-MAA) total-body imaging is considered a hallmark sign of patent right-to-left shunt. Herein, we present a unique case of a patient with Eisenmenger syndrome, whose 99mTc-MAA total-body imaging showed increased extrapulmonary activities only in the abdomen, pelvis, and both lower extremities and no activity was observed in the brain and upper extremities. The patient previously underwent a Potts shunt operation, which is a surgical approach to perform a side-to-side anastomosis between the lef...
Source: Hellenic Journal of Nuclear Medicine - August 26, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Correlations of the 68Ga-PSMA PET/CT derived primary prostate tumor PSMA expression parameters and metastatic patterns in patients with Gleason Score > 7 prostate cancer.
CONCLUSION: The PSMA-TV and TL-PSMA values are strong markers for metastasis prediction in patients with GS>7 PCa but no other PSMA expression parameters can distinguish between N1M0 and M1 groups. PMID: 32716402 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - July 29, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Automatic characterization of myocardial perfusion imaging polar maps employing deep learning and data augmentation.
CONCLUSION: The proposed deep learning model with data augmentation techniques performed better than the conventional semi-quantitative polar map analysis and competed with doctor's expertise in this particular patient cohort and image set. The model could potentially serve as an assisting tool to support interpretation of MPI studies or could be used for teaching purposes. PMID: 32716403 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - July 29, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Quantitative bone SPECT/CT applications for cartilaginous bone neoplasms.
CONCLUSION: Standardized uptake value obtained with bone SPECT/CT may be useful to differentiate benign from malignant cartilaginous bone neoplasms, thus helping the orthopedic surgeon towards the most appropriate treatment procedure. PMID: 32716404 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - July 29, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

CT guided mediastinal biopsy facilitated by PET/CT imaging: Our experience.
Authors: Exarhos D, Athanasiou S, Lazaridou E, Stefanou D, Aslanidi C, Samartzis A, Rondogianni P, Datseris I Abstract The purpose of this retrospective study is to assess the efficacy of mediastinal tumor biopsies guided by computed tomography (CT) and facilitated by positron emission tomography (PET)/CT in our hospital. We also wanted to prove the use of PET/CT in performing such biopsies. Fifty-two patients were biopsied under CT guidance with PET/CT visual co-registration (35) and facilitated PET/CT registration (17). In 49 patients, a diagnosis from the guided biopsy performed was successful and in 3 patients ...
Source: Hellenic Journal of Nuclear Medicine - July 29, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Diagnostic value of clinical parameters and parathyroid scintigraphy for asymptomatic primary hyperparathyroidism.
Authors: Ning Y, Chen D, Huang Z, Lou C Abstract OBJECTIVE: The purpose of this study was to evaluate the diagnostic value of clinical parameters and parathyroid scintigraphy for asymptomatic primary hyperparathyroidism (aPHPT), including quantitative parameter of laboratory and semiquantitative parameters derived from technetium-99m- metoxyisobutylisonitrile (99mTc-MIBI) single photon emission computed tomography/computed tomography (SPECT/CT). SUBJECTS AND METHODS: Two hundred and fourteen patients who had been diagnosed as PHPT and underwent surgical treatment were enrolled in this study. All patients were d...
Source: Hellenic Journal of Nuclear Medicine - July 29, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

An easy method for the evaluation of visual tumor heterogeneity of 18F-FDG PET/CT using 10-step color scale: A correlative study in patients with lung cancer.
CONCLUSION: In this study, we provide a new visual assessment criterion of TH with a strong inter-observer agreement. The visual analysis using the PHL method could be a potential marker for evaluating heterogeneous tumors. PMID: 32716407 [PubMed - as supplied by publisher] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - July 29, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Additive evidence of the competence of pregnancy-adapted YEARS algorithm in reducing the need for CTPA, Q and/or V/Q scintiscan.
Authors: Al Oweidat K, Al Ryalat SA, Al Husban N, Alhawari H, Ghareeb R, Ribie M, Jwaied S, Al Yasjeen S, Juweid ME Abstract OBJECTIVE: To determine whether a pregnancy-adapted clinical and D-dimer-based algorithm, termed the "YEARS algorithm," can reduce the need for radiological imaging, including lung scintigraphy in pregnant women with suspected pulmonary embolism (PE). PATIENTS AND METHODS: This retrospective study included all pregnant women with suspected PE between January 2014 and September 2019 who have undergone D-dimer testing and radiological imaging (computed tomography pulmonary angiogr...
Source: Hellenic Journal of Nuclear Medicine - July 29, 2020 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research