Serial changes of (18)F-FDG PET/CT findings in ischiopubic synchondrosis: comparison with contrast-enhanced MRI.
CONCLUSION: This is the first report showing serial changes of (18)F-FDG uptake in IPS, in comparison to MRI findings. PMID: 25679077 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

(18)F-FDG PET/CT contribution to diagnosis and treatment response of rhino-orbital-cerebral mucormycosis.
CONCLUSION: This case suggests that (18)F-FDG PET/CT could be considered as a valuable tool for the initial staging of RCM when compared with MRI and should be performed as soon as possible after the first clinical suspicion of this disease. In addition (18)F-FDG PET/CT may also be useful for the assessment of response to treatment. PMID: 25679078 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Multifocal septic osteomyelitis mimicking skeletal metastatic disease in a patient with prostate cancer.
In conclusion, we present a patient with known malignancy, fever, skeletal pain and multiple bone lesions in the (99m)Tc-MDP and the MRI examination, not due to metastatic disease but to septic arthritis. PMID: 25679079 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The prevalence of a false-positive myocardial perfusion stress SPET test in a skinny patient, induced by projection truncation.
In conclusion, it is suggested that in cases of very thin patients it is often necessary to avoid truncation artefacts by correctly positioning the patient's heart. PMID: 25679080 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

A simple graphical quantitative analysis of ultrasonography images to decide when to perform fine needle aspiration biopsy in diagnosing malignancy in solid thyroid nodules? A two centres prospective study.
Authors: Glogovšek M, Gaberšček S, Zorman M Abstract OBJECTIVE: Since the prevalence of thyroid nodules is high and ultrasonography (USG)-guided fine-needle aspiration biopsy (FNAB) as a diagnostic means cannot be performed in all cases, we aimed to evaluate the feasibility and applicability of simple graphical analysis of USG two-dimensional images, to identify patients with suspicious thyroid nodules who would benefit from FNAB. SUBJECTS AND METHODS: We studied prospectively 211 consecutive patients with thyroid nodules: 122 from the University Clinical Centre (UCC) of Maribor and 89 from the U...
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Diagnosis of high-risk patients with multivessel coronary artery disease by combined cardiac gated SPET imaging and coronary calcium score.
Authors: Kamínek M, Metelková I, Budíková M, Koranda P, Henzlova L, Havel M, Sovová E, Kincl V Abstract OBJECTIVE: The added value of coronary artery calcium (CAC) to SPET for identification of multivessel CAD has not been studied yet. The aim of this original study was to investigate CAC as an adjunct to gated single photon emission tomography (GSPET) in the detection of multivessel coronary artery disease (CAD). SUBJECTS AND METHODS: The study group consisted of 164 prospectively recruited patients without known CAD-123 (75%) men and 60 (37%) women, having diabetes type II, ...
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Can (18)F-FDG PET/CT scan change treatment planning and be prognostic in recurrent colorectal carcinoma? A prospective and follow-up study.
CONCLUSION: (18)F-FDG PET/CT was sensitive and accurate for the detection and staging of local and metastatic recurrent colorectal carcinoma, with higher specificity in the detection of local recurrences. The (18)F-FDG PET/CT scan induced treatment changes in 30/75 patients, including 12/32 patients in which surgical treatment was previously planned, and progression free survival time was significantly longer in these patients. PMID: 25840571 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Clinical issues regarding misclassification by Dixon based PET/MR attenuation correction.
CONCLUSION: Because no corrective method has been devised after a scan, we recommend that Dixon images with μ-maps should be checked before interpreting PET/MR images and emphasize the importance of hydration, pre-examination. Misclassification errors do not change the presence of (18)F-FDG uptake but can have significant impacts on PET quantification in affected bed positions. PMID: 25840572 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Fluorine-18-fluoroethylcholine PET/CT in the detection of prostate cancer: a South African experience.
CONCLUSION: Findings of this paper suggest that (18)F-FECh PET/CT in 30/40 cases (estimated as 75%) was helpful in the initial staging, restaging and lymph node detection of patients with PC. The SUVmax was not helpful. We diagnosed more PC cases in our African-American patients as compared to the Caucasian patients. PMID: 25840573 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

A probabilistic assessment of the diagnosis of paraganglioma/pheochromocytoma based on clinical criteria and biochemical/imaging findings.
CONCLUSION: Biochemical evaluation of PGL/P showed excellent diagnostic characteristics with post-test probabilities that are very different from the pre-test probabilities, thus a positive biochemical test is usually indicative of disease whereas a negative one usually rules out disease. The post-test probabilities of anatomical and functional imaging modalities (i.e. in nuclear medicine) were different from the pre-test probabilities but to a lesser degree than the biochemical tests; furthermore in biochemically-proven PGL/P a negative imaging modality is not useful, while a positive one may indicate only one of multiple...
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Correlative bone imaging in a case of Schnitzler's syndrome and brief review of the literature.
CONCLUSION: None of the imaging findings are specific, but they lead to a differential diagnosis including infiltrative diseases (e.g. systemic mastocytosis or Erdheim-Chester disease) and dysplastic diseases (e.g. melorheostosis, Camurati-Engelmann disease or van Buchem disease). The bone scintigraphy pattern may be very suggestive of the correct diagnosis and of bone involvement in this syndrome. PMID: 25840575 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Gastric Schwannoma mimicking malignant gastrointestinal stromal tumor and misdiagnosed by (18)F-FDG PET/CT.
Authors: Zhang Y, Li B, Cai L, Hou X, Shi H, Hou J Abstract Gastric Schwannoma is a rare benign mesenchymal tumor that accounts for only 0.2% of all gastric tumors. The current study presents a case of gastric Schwannoma misdiagnosed as malignant gastrointestinal stromal tumor (GIST) by esophagogastroduodenoscopy, endoscopic ultrasonography, and contrast-enhanced or not enhanced and (18)F-FDG PET/CT imaging. PMID: 25840576 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Is there an advantage in performing a combined examination: diuretic renal scintigraphy and low dose computed tomography compared to the separate use of these methods in urolithiasis.
Authors: Hadzhiyska V, Kostadinova I, Demirev A Abstract Ultrasonography (US), radiography of the kidneys, ureters and bladder (RKUB), intravenous urography (IVU) and especially non-enchanced CT are well established diagnostic modalities in screening patients with urolithiasis, while not always fully diagnostic especially when obstructive uropathy or calculous pyelonephritis are present . Diuretic renal scintigraphy (DRS) can determine obstruction, may differentiate between complete or partial, acute or chronic obstruction, but can not specify the cause and often the location of obstruction. The imaging protocol, i...
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Patterns of 18F-FDG PET images in patients with uncomplicated total hip arthroplasty.
CONCLUSION: Uptake of (18)F-FDG in the asymptomatic patients with THA is commonly visualized and appears to be confined to the proximal segment of the prosthesis with minimal or no activity in its femoral segment. PMID: 26187206 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Diagnostic and prognostic value of 18F-FDG PET/CT in comparison with morphological imaging in primary adrenal gland malignancies - a multicenter experience.
CONCLUSION: Our multicenter study demonstrated that (18)F-FDG PET/CT better than CECT diagnosed adrenal malignancies achieving also a good prognostic performance. Therefore management algorithms should include (18)F-FDG PET/CT. PMID: 26187207 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Comparison of image quality with 62Cu and 64Cu-labeled radiotracers in positron emission tomography whole-body phantom imaging.
CONCLUSIONS: Copper-64 radiotracers provide higher image quality than (62)Cu-radiotracers in whole-body tumor imaging only when the 3D acquisition mode and OSEM algorithm are applied. However, the quantitative values for smaller tumors may be slightly overestimated. PMID: 26187208 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The diagnostic role of 99mTc-dual receptor targeted probe and targeted peptide bombesin (RGD-BBN) SPET/CT in the detection of malignant and benign breast tumors and axillary lymph nodes compared to ultrasound.
This study aimed to explore the diagnostic role of a new dual receptor-targeted probe, integrin ανβ3 and gastrin releasing peptide receptor (GRPR) targeted peptide Glu-c(RGDyK)-bombesin (RGD-BBN) labeled with technetium-99m ((99m)Tc-RGD-BBN), using single photon emission tomography/computed tomography (SPET/CT) in the detection of breast tumor in comparison to ultrasound (US). SUBJECTS AND METHODS: One hundred and twenty six female patients with suspicious breast lesions who had already been scheduled for biopsy or surgery were enrolled in this study. All patients had previously underwent breast US and (9...
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The impact of transmission-emission misregistration on the interpretation of SPET/CT myocardial perfusion studies and the value of misregistration correction.
Authors: Apostolopoulos DJ, Gąsowska M, Savvopoulos CA, Skouras T, Spyridonidis T, Andrejczuk A, Vassilakos PJ Abstract OBJECTIVE: Previous studies indicate that the quality of single photon emission tomography/computed tomography (SPET/CT) myocardial perfusion imaging (MPI) is degraded by even mild transmission-emission misregistrations. The purpose of the current study was to investigate the impact of SPET/CT misalignment on the interpretation of MPI and examine the value of a commercial software application for registration correction. SUBJECTS AND METHODS: A total of 255 technetium-99m ((99m)Tc)-tetrofosmi...
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The role of cholescintigraphy in demonstrating delayed post prandial gallbladder motility in cirrhotic patients.
CONCLUSIONS: This study suggests that post prandial cholescintigraphy by (99m)Tc EHIDA demonstrated slower gallbladder motility in cirrhotic patients. The ejection period of cholescintigraphy by (99m)Tc-EHIDA can be used as an index of abnormal gallbladder motility. PMID: 26187211 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Comparison of SPET/CT, SPET and planar imaging using 99mTc-MIBI as independent techniques to support minimally invasive parathyroidectomy in primary hyperparathyroidism: A meta-analysis.
CONCLUSION: Our present meta-analysis showed that using (99m)Tc-MIBI, combining anatomical information of CT and functional abnormalities on SPET, as presented on SPET/CT was by far more sensitive and accurate than SPET or planar scintigraphy in localizing PHPT lesions. We firmly believe that this technique will be the main diagnostic means, to detect PHPT lesions and support minimally invasive parathyroidectomy. PMID: 26187212 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

The role of 18F-FDG PET/CT in the evaluation of pediatric transplant patients.
CONCLUSION: PET/CT may have an important role in follow-up of pediatric transplant patients. Further investigations with more patients are necessary to assess the validity of our findings. PMID: 26187213 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Appropriately regularized OSEM can improve the reconstructed PET images of data with low count statistics.
CONCLUSION: This work is relevant to future PET reconstruction of clinical images and PET-magnetic resonance investigations where the reduced injected dose will allow imaging a larger cohort of humans. PMID: 26187214 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Lymphoscintigraphy and sentinel lymph node biopsy, in cutaneous melanoma staging and treatment decisions.
CONCLUSION: Besides the well established primary tumor thickness being a predictor of SLN malignancy, we observed: acral body site location and nodular melanoma histological subtype to be significant independent factors in increasing the risk for regional metastases. Our results suport the clinical usefulness of SLNB within a multidisciplinary approach (dermatooncology, plastic/head and neck surgery, pathology, nuclear medicine), as a reliable method in staging and for treatment planning in melanoma patients. PMID: 26187215 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Current status of 18F-DOPA PET imaging in the detection of brain tumor recurrence.
CONCLUSION: The (18)F-DOPA PET/CT seems to be useful in the diagnosis of patients with suspected brain tumor recurrence, because of low signal ratio in normal brain white and grey matter, in particular as compared to (18)F-FDG PET/CT low performance. Related data are presented for other fluorinated amino acid tracers. Magnetic resonance imaging is the gold standard of diagnosis and (18)F-DOPA PET/CT is adjuvant to diagnosis. Further studies are needed to enrich our knowledge about this promising tracer,(18)F-DOPA, especially on its possible role on semi-quantitative measurements in brain tumors. PMID: 26187216 [PubMed ...
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Incidental possible diagnosis by 18F-fluorocholine PET/CT of Meckel's diverticulum and potential pitfalls.
CONCLUSION: In this particular case, we managed to clearly demonstrate the presence of a tubular blind ending structure arising from the distal ileum on the sagittal images. The careful identification of this structure indicated that tracer uptake was in a Meckel's diverticulum and not within a pelvic lymph node or pelvic organ hence excluding recurrent disease. PMID: 26187217 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Hepatobiliary scintigraphy with SPET in the diagnosis of bronchobiliary fistula due to a hydatid cyst.
In this report, we present the application of hepatobiliary scintigraphy using Tc-99m mebrofenin in the diagnosis of bronchobiliary fistula caused by a liver hydatid cyst, which penetrated the diaphragm. Hepatobiliary scintigraphy noticeably depicted the leakage of the tracer from the biliary system of the liver to the bronchial tree. Hepatobiliary scintigraphy stands as a robust modality in the accurate diagnosis and treatment planning of bronchobiliary fistulas. PMID: 26187218 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

18F-FDG PET/CT findings in a case of a semantic variant of primary progressive aphasia.
CONCLUSION: This case was reported to demonstrate the characteristic (18)F-FDG PET CT findings for a semantic variant of PPA. PMID: 26187219 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

Primary pulmonary artery sarcoma differentiated from pulmonary thromboembolism by ventilation-perfusion scan. Long survival of the patient.
CONCLUSION: We emphasize the difficulties in diagnosing PAS, the need to investigate this neoplasm in the differential diagnosis of PTE, the diagnostic value of different imaging techniques in the identification of the the tumor, and the efficacy of adjuvant chemotherapy in prolonging survival. PMID: 26187220 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research

[The role of positron emission tomography in in lymphoma diagnosis and treatment].
CONCLUSION: The PET/CT scan can identify the stages and evaluate treatment results, of lymphomas. PMID: 26187221 [PubMed - indexed for MEDLINE] (Source: Hellenic Journal of Nuclear Medicine)
Source: Hellenic Journal of Nuclear Medicine - November 18, 2015 Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research