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Incidence of Platelet Refractoriness in Adult Acute Leukemia Patients Receiving Prestorage Filtered Blood and Comparing With Historical Control
Conditions: Platelet Refractoriness in Adult Acute Leukemia Sponsors: Siriraj Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials

Utilizing 3D Printed Personalized Aortic Lesion Models in Preoperative Assessment
Conditions: Aortic Aneurysm Interventions: Other: historical control; Other: 3D printed lesion model Sponsors: Fu Jen Catholic University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 27, 2023 Category: Research Source Type: clinical trials

Clinical Evaluation of MyoCare in Europe (CEME): study protocol for a prospective, multicenter, randomized, double-blinded, and controlled clinical trial
This study will be the first randomized and controlled clinical trial in European children with spectacle lenses based on simultaneous competing defocus. The results will shed light on the clinical evidence of spectacle lenses relying on this new design for the management of myopia with results of efficacy in the non-Asiatic population.Trial registrationEU Clinical Trials Register (EudraCT) 2022 –001696. Registered on 27 April 2022. ClinicalTrials.gov NCT05919654. Registered on 26 June 2023. (Source: Trials)
Source: Trials - October 17, 2023 Category: Research Source Type: clinical trials

Q-HAM: a multicenter upfront randomized phase II trial of quizartinib and high-dose Ara-C plus mitoxantrone in relapsed/refractory AML with FLT3-ITD
ConclusionCurrently, there is no commonly accepted standard for salvage chemotherapy treatment. The objective of the salvage therapy is to reduce leukemic burden, achieve the best possible remission, and perform a hemopoietic stem-cell transplantation. Thus, in patients withFLT3-ITD mutation, the comparison of quizartinib with intensive salvage therapy versus chemotherapy alone appears as a logical consequence in terms of efficacy and safety.Ethics and disseminationEthical approval and approvals from the local and federal competent authorities were granted. Trial results will be reported via peer-reviewed journals and pres...
Source: Trials - September 15, 2023 Category: Research Source Type: clinical trials

De-novo Initiation of Letermovir vs Valganciclovir for Cytomegalovirus Prophylaxis in AA Kidney Trans Recip
Conditions:   Kidney Transplant; Complications;   CMV Interventions:   Drug: Letermovir 480 mg once daily;   Other: Historical/Control Sponsors:   Virginia Commonwealth University;   Merck Sharp & Dohme LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 21, 2023 Category: Research Source Type: clinical trials

Role of Natural Light in the Prevention of Delirium After Cardiac Surgery: a Prospective Observational Study With Historical Control
Conditions:   Intensive Care Unit Delirium;   Postoperative Delirium;   Cardiac Surgery Intervention:   Other: Exposure to totally artificial lighting Sponsor:   Azienda Ospedaliero-Universitaria di Parma Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 10, 2023 Category: Research Source Type: clinical trials