Body weight variability and the risk of liver-related outcomes in type 2 diabetes and steatotic liver disease: a cohort study
CONCLUSIONS: Increased BWV was associated with adverse liver outcomes in individuals with T2D and MASLD; however, in those who were physically active, it was not hazardous.PMID:38664236 | DOI:10.1002/oby.24035 (Source: Obesity)
Source: Obesity - April 25, 2024 Category: Eating Disorders & Weight Management Authors: Nathalie C Leite Claudia R L Cardoso Cristiane A Villela-Nogueira Gil F Salles Source Type: research
High serum levels of CCL11/Eotaxin-1 are associated with diabetic sensorimotor polyneuropathy and peripheral nerve function but not with cardiac autonomic neuropathy in people with type 2 diabetes
CONCLUSIONS: Serum CCL11/Eotaxin-1 is elevated in patients with DSPN and is associated with peripheral nerve dysfunction, in particular sensory nerve conduction velocity, suggesting that serum CCL11/Eotaxin 1 May be a potential biomarker for DSPN.CLINICAL TRIAL REGISTRATION: University Hospital Medical Information Network (UMIN) Clinical Trials Registry (UMIN000040631).PMID:38660919 | DOI:10.1080/00325481.2024.2347196 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - April 25, 2024 Category: Internal Medicine Authors: Yoshimasa Aso Toshie Iijima Teruo Jojima Masahiro Saito Dai Tanuma Masato Kase Shintaro Sakurai Takuya Tomaru Isao Usui Source Type: research
Novel subtype of obesity influencing the outcomes of sleeve gastrectomy: Familial aggregation of obesity
CONCLUSION: FAO patients is associated with decreased mid-to-long-term weight loss outcomes; the alleviation of T2DM, hyperlipidemia and NAFLD; and decreased incidence of acid reflux postoperatively.PMID:38659480 | PMC:PMC11036498 | DOI:10.3748/wjg.v30.i13.1887 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 25, 2024 Category: Gastroenterology Authors: Ze-Yu Wang Yun-Fei Qu Tian-Ming Yu Zeng-Lin Liu Yu-Gang Cheng Ming-Wei Zhong San-Yuan Hu Source Type: research
Novel subtype of obesity influencing the outcomes of sleeve gastrectomy: Familial aggregation of obesity
CONCLUSION: FAO patients is associated with decreased mid-to-long-term weight loss outcomes; the alleviation of T2DM, hyperlipidemia and NAFLD; and decreased incidence of acid reflux postoperatively.PMID:38659480 | PMC:PMC11036498 | DOI:10.3748/wjg.v30.i13.1887 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 25, 2024 Category: Gastroenterology Authors: Ze-Yu Wang Yun-Fei Qu Tian-Ming Yu Zeng-Lin Liu Yu-Gang Cheng Ming-Wei Zhong San-Yuan Hu Source Type: research
Matrix metallopeptidase 9 contributes to the beginning of plaque and is a potential biomarker for the early identification of atherosclerosis in asymptomatic patients with diabetes
CONCLUSION: MMP9 may contribute to the initiation of atherosclerosis and may be a potential biomarker for the early identification of atherosclerosis in patients with diabetes.CLINICAL TRIAL REGISTRATION: https://clinicaltrials.gov, identifier NCT04424706.PMID:38660518 | PMC:PMC11039961 | DOI:10.3389/fendo.2024.1369369 (Source: Atherosclerosis)
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Bingli Liu Liping Su Sze Jie Loo Yu Gao Ester Khin Xiaocen Kong Rinkoo Dalan Xiaofei Su Kok-Onn Lee Jianhua Ma Lei Ye Source Type: research
Macrophage polarization: an important role in inflammatory diseases
Front Immunol. 2024 Apr 10;15:1352946. doi: 10.3389/fimmu.2024.1352946. eCollection 2024.ABSTRACTMacrophages are crucial cells in the human body's innate immunity and are engaged in a variety of non-inflammatory reactions. Macrophages can develop into two kinds when stimulated by distinct internal environments: pro-inflammatory M1-like macrophages and anti-inflammatory M2-type macrophages. During inflammation, the two kinds of macrophages are activated alternatively, and maintaining a reasonably steady ratio is critical for maintaining homeostasis in vivo. M1 macrophages can induce inflammation, but M2 macrophages suppress...
Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Min Luo Fukun Zhao Huan Cheng Mu Su Yuanmin Wang Source Type: research
Uptake of self-management education programmes for people with type 2 diabetes in primary care through the embedding package: a cluster randomised control trial and ethnographic study
This study reports on the effectiveness of the E... (Source: BMC Family Practice)
Source: BMC Family Practice - April 25, 2024 Category: Primary Care Authors: Melanie J Davies, Danielle H Bodicoat, Alan Brennan, Simon Dixon, Helen Eborall, Agnieszka Glab, Laura J Gray, Michelle Hadjiconstantinou, Lisa Huddlestone, Nicky Hudson, Anju Keetharuth, Kamlesh Khunti, Graham Martin, Alison Northern, Rebecca Pritchard, Tags: Research Source Type: research
Associations between cardiometabolic indices and the risk of diabetic kidney disease in patients with type 2 diabetes
This study was designed to assess the associations between emerging cardiometabolic indices —the atherogenic index of plasma (AIP), the stress hyperglycemia ratio (SHR), the triglyceride-glucose (TyG) index, an... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 25, 2024 Category: Cardiology Authors: Han Yan, Qing Zhou, Yaqiong Wang, Yifan Tu, Yuxin Zhao, Jie Yu, Kuangyang Chen, Yepeng Hu, Qiao Zhou, Wen Zhang and Chao Zheng Tags: Research Source Type: research
Brain-Derived Neurotrophic Factor is Associated with Self-Reported
Quality of Sleep in Type 2 Diabetes Patients in Ghana
Conclusion In this study population, patients with T2DM had a high burden
of self-reported poor quality of sleep and shorter sleep duration compared to
the nondiabetic controls. T2DM interacts negatively with serum BDNF levels to
affect sleep quality. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - April 25, 2024 Category: Endocrinology Authors: Agyekum, Jennifer Adjepong Yeboah, Kwame Tags: Article Source Type: research
Aminotransferases as causal factors for metabolic syndrome: A bidirectional Mendelian randomization study
ConclusionsOur bidirectional MR analyses suggest that ALT and AST are causally associated with several metabolic syndrome-related traits, especially hypertension and type 2 diabetes. These findings highlight the potential role of aminotransferases as biomarkers and therapeutic targets for metabolic syndrome. (Source: PLoS One)
Source: PLoS One - April 25, 2024 Category: Biomedical Science Authors: Meng Lingyu Source Type: research
Vitamin B12 deficiency in diabetic patients treated with metformin: A cross-sectional study
This study set out to evaluate the rate of vitamin B12 deficiency in Vietnamese patients with type 2 diabetes who were t reated with metformin and to investigate factors associated with vitamin B12 deficiency. This is a cross-sectional study that was conducted in Vinmec Central Park Hospital from February to June 2023. The clinical and paraclinical characteristics of the participants were recorded, and the levels of v itamin B12 and folate were measured. The rate of vitamin B12 deficiency in patients treated with metformin was found to be 18.6%. Further, the duration of diabetes, duration of metformin use, metformin dose, ...
Source: PLoS One - April 25, 2024 Category: Biomedical Science Authors: Dat Tan Huynh Source Type: research
Effect of the SARS-CoV-2 pandemic on metabolic control in patients with type 2 diabetes: a 5-year cohort follow-up managed by a dynamic multidisciplinary team in Northeastern Mexico
The SARS-CoV-2 pandemic brought a radical shift in the healthcare system and suboptimal care for vulnerable patients, such as those with Type 2 Diabetes Mellitus (T2D). Therefore, we compared metabolic control... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - April 25, 2024 Category: Endocrinology Authors: Devany Paola Morales-Rodriguez, Arnulfo Gonz ález-Cantú, Arnulfo Garza-Silva, Andrea Rivera-Cavazos, Iván Francisco Fernández-Chau, Andrea Belinda Cepeda-Medina, Miguel Angel Sanz-Sánchez, Gerardo Francisco del Rio-Parra, María Angelina Torres-Fuent Tags: Research Source Type: research
Contribution of systemic factors on macular vessel density: a sex-specific population-based study
ConclusionsThis large cross-sectional study shows that older age and type 2 diabetes mellitus are associated with lower superficial and deep retinal capillary vessel density in men. This may help clinicians better understand how systemic factors influence retinal vessel density in different genders and future studies can ascertain more potential sex differences. (Source: Japanese Journal of Ophthalmology)
Source: Japanese Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Source Type: research
Vitamin D efficacy in type 1 and type 2 diabetes
AbstractIt is well known that vitamin D has a profound effect on calcium and bone metabolism, but its influence on other organs (extraskeletal effect) has been proposed. Consistently, vitamin D deficiency is associated with an increased incidence of various diseases, including type 1 and type 2 diabetes, as reported by many observational studies. However, there has been no consensus on whether vitamin D deficiency is a causative factor in the incidence of diabetes mellitus. There have been no randomized controlled trials (RCTs) aimed at preventing the onset of type 1 diabetes with vitamin D intake. In addition, the results...
Source: Journal of Bone and Mineral Metabolism - April 25, 2024 Category: Orthopaedics Source Type: research
Subclinical Atherosclerosis to Guide Treatment in Dyslipidemia and Diabetes Mellitus
AbstractPurpose of ReviewDyslipidemia and type 2 diabetes mellitus are two common conditions that are associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD). In this review, we aimed to provide an in-depth and contemporary review of non-invasive approaches to assess subclinical atherosclerotic burden, predict cardiovascular risk, and guide appropriate treatment strategies. We focused this paper on two main imaging modalities: coronary artery calcium (CAC) score and computed tomography coronary angiography.Recent FindingsRecent longitudinal studies have provided stronger evidence on the relation...
Source: Current Atherosclerosis Reports - April 25, 2024 Category: Cardiology Source Type: research
