High serum levels of CCL11/Eotaxin-1 are associated with diabetic sensorimotor polyneuropathy and peripheral nerve function but not with cardiac autonomic neuropathy in people with type 2 diabetes
CONCLUSIONS: Serum CCL11/Eotaxin-1 is elevated in patients with DSPN and is associated with peripheral nerve dysfunction, in particular sensory nerve conduction velocity, suggesting that serum CCL11/Eotaxin 1 May be a potential biomarker for DSPN.CLINICAL TRIAL REGISTRATION: University Hospital Medical Information Network (UMIN) Clinical Trials Registry (UMIN000040631).PMID:38660919 | DOI:10.1080/00325481.2024.2347196 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - April 25, 2024 Category: Internal Medicine Authors: Yoshimasa Aso Toshie Iijima Teruo Jojima Masahiro Saito Dai Tanuma Masato Kase Shintaro Sakurai Takuya Tomaru Isao Usui Source Type: research
Impact of on-call shifts on working memory and the role of burnout, sleep, and mental well-being in trainee physicians
CONCLUSION: Working more on-call shifts is associated with compromised WM. Trainee physicians who experienced more depressive symptoms and burnout had worse WM.PMID:38656827 | DOI:10.1080/00325481.2024.2347195 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - April 24, 2024 Category: Internal Medicine Authors: Abeer F Almarzouki Source Type: research
Is the fluoroquinolone combination necessary for empirical antibiotic regimen in severe community-acquired pneumonia?
CONCLUSION: In patients with severe CAP, there were no differences in the clinical outcomes, including mortality, between the TZP and FQ combination therapy and TZP monotherapy. FQ combination was not significantly associated with in-hospital mortality.PMID:38658366 | DOI:10.1080/00325481.2024.2347830 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - April 24, 2024 Category: Internal Medicine Authors: Seungtak Oh Wooyoung Jang Bongyoung Kim Source Type: research
Impact of on-call shifts on working memory and the role of burnout, sleep, and mental well-being in trainee physicians
CONCLUSION: Working more on-call shifts is associated with compromised WM. Trainee physicians who experienced more depressive symptoms and burnout had worse WM.PMID:38656827 | DOI:10.1080/00325481.2024.2347195 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - April 24, 2024 Category: Internal Medicine Authors: Abeer F Almarzouki Source Type: research
Gallbladder cancer: surgical treatment, immunotherapy, and targeted therapy
Postgrad Med. 2024 Apr 23:1-14. doi: 10.1080/00325481.2024.2345585. Online ahead of print.ABSTRACTGallbladder cancer is a common type of biliary tract tumor. Optimal management for early stage cases typically involves radical excision as the primary treatment modality. Various surgical techniques, including laparoscopic, robotic, and navigational surgery, have demonstrated favorable clinical outcomes in radical gallbladder excision. Unfortunately, most patients are ineligible for surgical intervention because of the advanced stage of the disease upon diagnosis. Consequently, non-surgical interventions, such as chemotherapy...
Source: Postgraduate Medicine - April 18, 2024 Category: Internal Medicine Authors: Yanjun Sun Junfeng Gong Zhuang Li Lin Han Dengqun Sun Source Type: research
Gallbladder cancer: surgical treatment, immunotherapy, and targeted therapy
Postgrad Med. 2024 Apr 18. doi: 10.1080/00325481.2024.2345585. Online ahead of print.ABSTRACTGallbladder cancer is a common type of biliary tract tumor. Optimal management for early stage cases typically involves radical excision as the primary treatment modality. Various surgical techniques, including laparoscopic, robotic, and navigational surgery, have demonstrated favorable clinical outcomes in radical gallbladder excision. Unfortunately, most patients are ineligible for surgical intervention because of the advanced stage of the disease upon diagnosis. Consequently, non-surgical interventions, such as chemotherapy, rad...
Source: Postgraduate Medicine - April 18, 2024 Category: Internal Medicine Authors: Yanjun Sun Junfeng Gong Zhuang Li Lin Han Dengqun Sun Source Type: research
Splenectomy versus splenic preservation in total gastrectomy for gastric cancer: a systematic review and meta-analysis comparing survival benefits and short-term complications
CONCLUSION: Despite the lack of significant differences in certain individual complications and postoperative mortality, the broader pattern of our data suggests that SP is associated with a greater overall frequency of postoperative complications, without providing additional survival benefits compared to splenic preservation. Thus, the routine implementation of SP is not advocated.PMID:38567398 | DOI:10.1080/00325481.2024.2333233 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - April 3, 2024 Category: Internal Medicine Authors: Da Wang Jingyao Ren Yuanyuan Wang Xiaohua Dong Shuo Liu Tianyi Liao Lihui Zhu Miao Yu Hui Cai Source Type: research
