Predicting ventilator-associated pneumonia in elderly patients requiring mechanical ventilation through the detection in tracheal aspirates
CONCLUSION: The detection of AM, pepsin, and LLMI in tracheal aspirates has promising clinical utility as an early warning biomarker of VAP in elderly patients undergoing mechanical ventilation.PMID:38032178 | DOI:10.1080/00325481.2023.2288559 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 30, 2023 Category: Internal Medicine Authors: Dan Wang Peng Zhao Yan-Xin Liu Peng Wang Mei-Liang Gong Ge-Ping Qu Xiang-Qun Fang Ya-Ping Qian Source Type: research

Overuse of long-acting β < sub > 2 < /sub > -agonist/inhaled corticosteroids in patients with chronic obstructive pulmonary disease: time to rethink prescribing patterns
We describe practical recommendations for primary care physicians to optimize therapy for their patients and prevent overuse of ICS-based regimens. We advocate adherence to current recommendations and a greater focus on effective treatments to successfully control symptoms, minimize exacerbation risk, preserve lung function, maximize patient outcomes, and reduce the burden of drug-related adverse events.PMID:38032494 | DOI:10.1080/00325481.2023.2284650 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 30, 2023 Category: Internal Medicine Authors: Stephen A Brunton D Kyle Hogarth Source Type: research

Exploring factors related to clinically advanced fibrosis in patients with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis
CONCLUSION: This study highlights the need for early screening and proactive management of metabolic risk factors for patients with NAFLD/NASH. The findings indicate a notable prevalence of obesity in the study population, a need for specialist referral for those at High-Risk of advanced fibrosis, and the importance of routine labs to evaluate metabolic factors. Primary care providers may be ideal providers to target these interventions and address this care need.PMID:38032542 | DOI:10.1080/00325481.2023.2288560 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 30, 2023 Category: Internal Medicine Authors: Anthony Yu Alexandra Ritenour Jennifer Vincent Chanhyun Park Karen Rascati Paul Godley Source Type: research

Generalized pustular psoriasis: practical recommendations for Spanish primary care and emergency physicians
Postgrad Med. 2023 Nov 29:1-9. doi: 10.1080/00325481.2023.2285730. Online ahead of print.ABSTRACTGeneralized pustular psoriasis (GPP) is a rare chronic inflammatory skin disease that can lead to life-threatening complications and require emergency medical treatment. Recurrent GPP flares are characterized by the sudden onset of widespread erythematous skin rash with sterile pustules, at times associated with fever, chills, general malaise, and other systemic inflammatory manifestations. Systemic complications such as cardiorespiratory failure, infections, and sepsis are potentially life-threatening and can result in an emer...
Source: Postgraduate Medicine - November 29, 2023 Category: Internal Medicine Authors: Raquel Rivera-Diaz Francisco Epelde Julio Antonio Heras-Hitos Ana Mar ía Martínez Virto Airam Jenny D ávalos Marin Mar ía Rosa Senán Sanz Jos é Manuel Carrascosa Source Type: research

Premarital hemoglobinopathy screening program results of a province in the Black Sea region of Turkey: three years' experience
CONCLUSIONS: This study presents the results of the national hemoglobinopathy screening program in Northern Turkey and the β-thal and the abnormal HbS rates were found to be low. The data obtained will be useful in monitoring hemoglobinopathy disorders and evaluating the current program's effectiveness in the future. It will allow decision-makers to implement policy changes and prioritize new programs.PMID:38019185 | DOI:10.1080/00325481.2023.2285726 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 29, 2023 Category: Internal Medicine Authors: Sule Ozdem ır Muhammet Ali Oruc Bahad ır Yazıcıoglu Sibel Turkan Source Type: research

Generalized pustular psoriasis: practical recommendations for Spanish primary care and emergency physicians
Postgrad Med. 2023 Nov 29:1-9. doi: 10.1080/00325481.2023.2285730. Online ahead of print.ABSTRACTGeneralized pustular psoriasis (GPP) is a rare chronic inflammatory skin disease that can lead to life-threatening complications and require emergency medical treatment. Recurrent GPP flares are characterized by the sudden onset of widespread erythematous skin rash with sterile pustules, at times associated with fever, chills, general malaise, and other systemic inflammatory manifestations. Systemic complications such as cardiorespiratory failure, infections, and sepsis are potentially life-threatening and can result in an emer...
Source: Postgraduate Medicine - November 29, 2023 Category: Internal Medicine Authors: Raquel Rivera-Diaz Francisco Epelde Julio Antonio Heras-Hitos Ana Mar ía Martínez Virto Airam Jenny D ávalos Marin Mar ía Rosa Senán Sanz Jos é Manuel Carrascosa Source Type: research

Premarital hemoglobinopathy screening program results of a province in the Black Sea region of Turkey: three years' experience
CONCLUSIONS: This study presents the results of the national hemoglobinopathy screening program in Northern Turkey and the β-thal and the abnormal HbS rates were found to be low. The data obtained will be useful in monitoring hemoglobinopathy disorders and evaluating the current program's effectiveness in the future. It will allow decision-makers to implement policy changes and prioritize new programs.PMID:38019185 | DOI:10.1080/00325481.2023.2285726 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 29, 2023 Category: Internal Medicine Authors: Sule Ozdem ır Muhammet Ali Oruc Bahad ır Yazıcıoglu Sibel Turkan Source Type: research

Obstructive sleep apnea increases the risk of herpes zoster and postherpetic neuralgia
CONCLUSION: OSA increases the risk of not only HZ but also PHN. Therefore, patients with OSA should be aware of the potential effect of the disease on their stress levels, as well as the increased risk of developing HZ and PHN.PMID:38011906 | DOI:10.1080/00325481.2023.2288562 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 27, 2023 Category: Internal Medicine Authors: Chih-An Wang Wen-Che Hsieh Tzu-Ju Hsu Fuu-Jen Tsai Chao-Yu Hsu Source Type: research

Vaccination coverage of children with rheumatic diseases compared with healthy controls: a retrospective case-control study
CONCLUSION: Vaccination coverage of PedRD patients has been shown to lag behind the routine vaccination schedule (71.4%). In addition to new recommendations, electronic health system records for vaccination may be appropriate for the follow-up of these patients, and the addition of reminder alerts may be useful to reduce the rate of missed vaccinations.PMID:37997766 | DOI:10.1080/00325481.2023.2287988 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 24, 2023 Category: Internal Medicine Authors: Özlem Akgün Fatma G ül Demirkan G ülşah Kavrul Kayaalp Merve Erdemir Nergis Akay Figen Çakmak Mustafa Önel Gonca Keskindemirci Rukiye Eker Ömeroğlu Emine G ülbin Gökçay Nuray Aktay Ayaz Source Type: research

Differentiating between segmental arterial mediolysis and other arterial vasculopathies to establish an early diagnosis - a systematic literature review and proposal of new diagnostic criteria
Postgrad Med. 2023 Nov 24. doi: 10.1080/00325481.2023.2288561. Online ahead of print.ABSTRACTSegmental arterial mediolysis (SAM) is a rare vascular disease, characterized by acute but transient vulnerability of the wall of medium-sized arteries. The most characteristic feature of SAM is its biphasic course: an injurious phase marked by acute weakness of the arterial wall leading to acute dissection and/or hemorrhage, followed by a reparative phase in which granulation tissue and fibrosis restore the injured arterial wall. Residual stenosis, aneurysms, and/or arterial wall irregularities may remain visible on future imaging...
Source: Postgraduate Medicine - November 24, 2023 Category: Internal Medicine Authors: Daan J L van Twist Y Appelboom Cesar Magro-Checa Mark Haagmans Robert Riedl Ozan Yazar Lee H Bouwman Guy J M Mostard Source Type: research

Vaccination coverage of children with rheumatic diseases compared with healthy controls: a retrospective case-control study
CONCLUSION: Vaccination coverage of PedRD patients has been shown to lag behind the routine vaccination schedule (71.4%). In addition to new recommendations, electronic health system records for vaccination may be appropriate for the follow-up of these patients, and the addition of reminder alerts may be useful to reduce the rate of missed vaccinations.PMID:37997766 | DOI:10.1080/00325481.2023.2287988 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 24, 2023 Category: Internal Medicine Authors: Özlem Akgün Fatma G ül Demirkan G ülşah Kavrul Kayaalp Merve Erdemir Nergis Akay Figen Çakmak Mustafa Önel Gonca Keskindemirci Rukiye Eker Ömeroğlu Emine G ülbin Gökçay Nuray Aktay Ayaz Source Type: research

Differentiating between segmental arterial mediolysis and other arterial vasculopathies to establish an early diagnosis - a systematic literature review and proposal of new diagnostic criteria
Postgrad Med. 2023 Nov 24. doi: 10.1080/00325481.2023.2288561. Online ahead of print.ABSTRACTSegmental arterial mediolysis (SAM) is a rare vascular disease, characterized by acute but transient vulnerability of the wall of medium-sized arteries. The most characteristic feature of SAM is its biphasic course: an injurious phase marked by acute weakness of the arterial wall leading to acute dissection and/or hemorrhage, followed by a reparative phase in which granulation tissue and fibrosis restore the injured arterial wall. Residual stenosis, aneurysms, and/or arterial wall irregularities may remain visible on future imaging...
Source: Postgraduate Medicine - November 24, 2023 Category: Internal Medicine Authors: Daan J L van Twist Y Appelboom Cesar Magro-Checa Mark Haagmans Robert Riedl Ozan Yazar Lee H Bouwman Guy J M Mostard Source Type: research

Vaccination coverage of children with rheumatic diseases compared with healthy controls: a retrospective case-control study
CONCLUSION: Vaccination coverage of PedRD patients has been shown to lag behind the routine vaccination schedule (71.4%). In addition to new recommendations, electronic health system records for vaccination may be appropriate for the follow-up of these patients, and the addition of reminder alerts may be useful to reduce the rate of missed vaccinations.PMID:37997766 | DOI:10.1080/00325481.2023.2287988 (Source: Postgraduate Medicine)
Source: Postgraduate Medicine - November 24, 2023 Category: Internal Medicine Authors: Özlem Akgün Fatma G ül Demirkan G ülşah Kavrul Kayaalp Merve Erdemir Nergis Akay Figen Çakmak Mustafa Önel Gonca Keskindemirci Rukiye Eker Ömeroğlu Emine G ülbin Gökçay Nuray Aktay Ayaz Source Type: research

Differentiating between segmental arterial mediolysis and other arterial vasculopathies to establish an early diagnosis - a systematic literature review and proposal of new diagnostic criteria
Postgrad Med. 2023 Nov 24. doi: 10.1080/00325481.2023.2288561. Online ahead of print.ABSTRACTSegmental arterial mediolysis (SAM) is a rare vascular disease, characterized by acute but transient vulnerability of the wall of medium-sized arteries. The most characteristic feature of SAM is its biphasic course: an injurious phase marked by acute weakness of the arterial wall leading to acute dissection and/or hemorrhage, followed by a reparative phase in which granulation tissue and fibrosis restore the injured arterial wall. Residual stenosis, aneurysms, and/or arterial wall irregularities may remain visible on future imaging...
Source: Postgraduate Medicine - November 24, 2023 Category: Internal Medicine Authors: Daan J L van Twist Y Appelboom Cesar Magro-Checa Mark Haagmans Robert Riedl Ozan Yazar Lee H Bouwman Guy J M Mostard Source Type: research