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Circulating sortilin level as a potential biomarker for coronary atherosclerosis and diabetes mellitus
A previous genome-wide association study showed that a genetic variant of sortilin was associated with the risk of coronary artery disease (CAD). However, the role of circulating sortilin is still unknown. We ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 20, 2017 Category: Cardiology Authors: Tae Jung Oh, Chang Ho Ahn, Bo-Rahm Kim, Kyoung Min Kim, Jae Hoon Moon, Soo Lim, Kyong Soo Park, Cheong Lim, HakChul Jang and Sung Hee Choi Source Type: research

Mirroring the CANTOS revolution: is anti-inflammatory therapy for diabetes just around the corner?
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 19, 2017 Category: Cardiology Authors: Alexander Tenenbaum and Enrique Z. Fisman Source Type: research

Erratum to: Impact of metabolic syndrome and its components on heart rate variability during hemodialysis: a cross-sectional study
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 14, 2017 Category: Cardiology Authors: Yu-Ming Chang, Chih-Chung Shiao, Ya-Ting Huang, I-Ling Chen, Chuan-Lan Yang, Show-Chin Leu, Hung-Li Su, Jsun-Liang Kao, Shih-Ching Tsai, Rong-Na Jhen and Ching-Cherng Uen Source Type: research

Symmetric and asymmetric dimethylarginine as risk markers of cardiovascular disease, all-cause mortality and deterioration in kidney function in persons with type 2 diabetes and microalbuminuria
To evaluate symmetric dimethylarginine (SDMA) and asymmetric dimethylarginine (ADMA) as risk markers of cardiovascular disease, all-cause mortality and deterioration in renal function in a well characterised t... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 11, 2017 Category: Cardiology Authors: Emilie H. Zobel, Bernt Johan von Scholten, Henrik Reinhard, Frederik Persson, Tom Teerlink, Tine W. Hansen, Hans-Henrik Parving, Peter K. Jacobsen and Peter Rossing Source Type: research

The impact of DPP-4 inhibitors on long-term survival among diabetic patients after first acute myocardial infarction
Previous studies regarding the cardioprotective effects of dipeptidyl peptidase 4 (DPP-4) inhibitors have not provided sufficient evidence of a relationship between DPP-4 inhibition and actual cardiovascular o... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 11, 2017 Category: Cardiology Authors: Mei-Tzu Wang, Sheng-Che Lin, Pei-Ling Tang, Wang-Ting Hung, Chin-Chang Cheng, Jin-Shiou Yang, Hong-Tai Chang, Chun-Peng Liu, Guang-Yuan Mar and Wei-Chun Huang Source Type: research

Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia
Omentin-1, also known as Intelectin-1 (ITLN1), is an adipokine with plasma levels associated with diabetes, obesity, and coronary artery disease. Recent studies suggest that ITLN1 can mitigate myocardial ische... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 7, 2017 Category: Cardiology Authors: Louis A. Saddic, Sarah M. Nicoloro, Olga T. Gupta, Michael P. Czech, Joshua Gorham, Stanton K. Shernan, Christine E. Seidman, Jon G. Seidman, Sary F. Aranki, Simon C. Body, Timothy P. Fitzgibbons and Jochen D. Muehlschlegel Source Type: research

Diabetic retinopathy is associated with diastolic dysfunction in type 2 diabetic patients with non-ischemic dilated cardiomyopathy
To investigate the association between diabetic retinopathy (DR) and myocardial dysfunction in patients with type 2 diabetes and dilated cardiomyopathy (dCMP). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Yoo-Ri Chung, Se-Jun Park, Ka Young Moon, Seoyoung Annie Choi, Hong-Seok Lim, Sung Wook Park, Jeong Hun Kim and Kihwang Lee Source Type: research

In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats
Emerging evidence suggests that specific (poly)phenols may constitute new preventative strategies to counteract cell oxidative stress and myocardial tissue inflammation, which have a key role in the patho-phys... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Monia Savi, Leonardo Bocchi, Pedro Mena, Margherita Dall ’Asta, Alan Crozier, Furio Brighenti, Donatella Stilli and Daniele Del Rio Source Type: research

Reduced HDL function in children and young adults with type 1 diabetes
Patients with type 1 diabetes (T1D) are at increased risk of cardiovascular disease (CVD). Measures of high-density lipoprotein (HDL) function provide a better risk estimate for future CVD events than serum le... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Martin Heier, Mark S. Borja, Cathrine Brunborg, Ingebj ørg Seljeflot, Hanna Dis Margeirsdottir, Kristian F. Hanssen, Knut Dahl-Jørgensen and Michael N. Oda Source Type: research

Red blood cell distribution width as a prognostic marker in patients with heart failure and diabetes mellitus
Red blood cell distribution width (RDW) is an established prognostic marker in acute and chronic heart failure (HF). Recent studies have pointed out a link among RDW, diabetes mellitus (DM) and inflammation. W... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Andrew Xanthopoulos, Gregory Giamouzis, Andreas Melidonis, Takeshi Kitai, Efi Paraskevopoulou, Pinelopi Paraskevopoulou, Sotirios Patsilinakos, Filippos Triposkiadis and John Skoularigis Source Type: research

Westernization of lifestyle affects quantitative and qualitative changes in adiponectin
Although Japanese –Americans and native Japanese share the same genetic predispositions, they live different lifestyles, resulting in insulin resistance in Japanese–Americans. We investigated whether the quanti... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Mitsunobu Kubota, Masayasu Yoneda, Norikazu Maeda, Haruya Ohno, Kenji Oki, Tohru Funahashi, Iichiro Shimomura and Noboru Hattori Source Type: research

Sex difference in the risk for exercise-induced albuminuria correlates with hemoglobin A1C and abnormal exercise ECG test findings
Albuminuria is an established marker for endothelial dysfunction and cardiovascular risk in diabetes and prediabetes. Exercise induced albuminuria (EiA) appears earlier and may be a more sensitive biomarker fo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 23, 2017 Category: Cardiology Authors: Rafael Y. Brzezinski, Inbal Etz-Hadar, Ayelet Grupper, Michal Ehrenwald, Itzhak Shapira, David Zeltser, Shlomo Berliner, Ori Rogowski, Roy Eldor and Shani Shenhar-Tsarfaty Source Type: research

Impact of glycemic control on aortic stiffness, left ventricular mass and diastolic longitudinal function in type 2 diabetes mellitus
Poor glycemic control is associated with impaired left ventricular (LV) diastolic function in patients with type 2 diabetes mellitus (T2DM). Inappropriate LV mass increase and accelerated aortic stiffening wer... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 17, 2017 Category: Cardiology Authors: Michaela Kozakova, Carmela Morizzo, Alan G. Fraser and Carlo Palombo Source Type: research

The regulatory role of DPP4 in atherosclerotic disease
The increasing prevalence of atherosclerosis has become a worldwide health concern. Although significant progress has been made in the understanding of atherosclerosis pathogenesis, the underlying mechanisms a... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 15, 2017 Category: Cardiology Authors: Lihua Duan, Xiaoquan Rao, Chang Xia, Sanjay Rajagopalan and Jixin Zhong Source Type: research

Elevated serum fibroblast growth factor 23 levels as an indicator of lower extremity atherosclerotic disease in Chinese patients with type 2 diabetes mellitus
Recently, basic and clinical studies have provided evidence supporting the relationship between circulating levels of fibroblast growth factor (FGF) 23 and the development of atherosclerosis. Given that diabet... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 15, 2017 Category: Cardiology Authors: Xingxing He, Xiang Hu, Xiaojing Ma, Hang Su, Lingwen Ying, Jiahui Peng, Xiaoping Pan, Yuqian Bao, Jian Zhou and Weiping Jia Source Type: research

Multipolar pacing by cardiac resynchronization therapy with a defibrillators treatment in type 2 diabetes mellitus failing heart patients: impact on responders rate, and clinical outcomes
Type 2 diabetes mellitus (T2DM) is a multi factorial disease, affecting clinical outcomes in failing heart patients treated by cardiac resynchronization therapy with a defibrillator (CRT-d). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 9, 2017 Category: Cardiology Authors: Celestino Sardu, Michelangela Barbieri, Matteo Santamaria, Valerio Giordano, Cosimo Sacra, Pasquale Paolisso, Alessandro Spirito, Raffaele Marfella, Giuseppe Paolisso and Maria Rosaria Rizzo Source Type: research

Prognostic value of plasma DPP4 activity in ST-elevation myocardial infarction
Dipeptidyl peptidase-4 (DPP4) regulates blood glucose levels and inflammation, and it is also implicated in the pathophysiological process of myocardial infarction (MI). Plasma DPP4 activity (DPP4a) may provid... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 6, 2017 Category: Cardiology Authors: Jing-Wei Li, Yun-Dai Chen, Wei-Ren Chen, Qi You, Bo Li, Hao Zhou, Ying Zhang and Tian-Wen Han Source Type: research

The effects of basal insulin peglispro vs. insulin glargine on lipoprotein particles by NMR and liver fat content by MRI in patients with diabetes
In Phase 2/3 studies of basal insulin peglispro (BIL) compared to insulin glargine, patients with type 1 or type 2 diabetes previously treated with insulin and randomized to BIL had an increase in serum trigly... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 6, 2017 Category: Cardiology Authors: Trevor J. Orchard, Bertrand Cariou, Margery A. Connelly, James D. Otvos, Shuyu Zhang, Caryl J. Antalis, Tibor Ivanyi and Byron J. Hoogwerf Source Type: research

Impact of diabetes duration and degree of carotid artery stenosis on major adverse cardiovascular events: a single-center, retrospective, observational cohort study
We aimed to investigate the impact of diabetes duration and carotid artery stenosis (CAS) on the occurrence of major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus (T2DM) withou... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 6, 2017 Category: Cardiology Authors: Minsu Noh, Hyunwook Kwon, Chang Hee Jung, Sun U. Kwon, Min Seon Kim, Woo Je Lee, Joong Yeol Park, Youngjin Han, Hyangkyoung Kim, Tae-Won Kwon and Yong-Pil Cho Source Type: research

Platelets, diabetes and myocardial ischemia/reperfusion injury
Mechanisms underlying the pathogenesis of ischemia/reperfusion injury are particularly complex, multifactorial and highly interconnected. A complex and entangled interaction is also emerging between platelet f... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 31, 2017 Category: Cardiology Authors: Isabella Russo, Claudia Penna, Tiziana Musso, Jasmin Popara, Giuseppe Alloatti, Franco Cavalot and Pasquale Pagliaro Source Type: research

Design and rationale of the ODYSSEY DM-DYSLIPIDEMIA trial: lipid-lowering efficacy and safety of alirocumab in individuals with type 2 diabetes and mixed dyslipidaemia at high cardiovascular risk
Type 2 diabetes mellitus (T2DM) is often associated with mixed dyslipidaemia, where non-high-density lipoprotein cholesterol (non-HDL-C) levels may more closely align with cardiovascular risk than low-density ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 25, 2017 Category: Cardiology Authors: Dirk M üller-Wieland, Lawrence A. Leiter, Bertrand Cariou, Alexia Letierce, Helen M. Colhoun, Stefano Del Prato, Robert R. Henry, Francisco J. Tinahones, Lisa Aurand, Jaman Maroni, Kausik K. Ray and Maja Bujas-Bobanovic Source Type: research

The addition of vildagliptin to metformin prevents the elevation of interleukin 1 ß in patients with type 2 diabetes and coronary artery disease: a prospective, randomized, open-label study
Patients with type 2 diabetes present with an accelerated atherosclerotic process. Animal evidence indicates that dipeptidyl peptidase-4 inhibitors (gliptins) have anti-inflammatory and anti-atherosclerotic ef... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 22, 2017 Category: Cardiology Authors: Arwa Younis, Dana Eskenazi, Ronen Goldkorn, Jonathan Leor, Nili Naftali-Shani, Enrique Z. Fisman, Alexander Tenenbaum, Ilan Goldenberg and Robert Klempfner Source Type: research

PRotective Effect on the coronary microcirculation of patients with DIabetes by Clopidogrel or Ticagrelor (PREDICT): study rationale and design. A randomized multicenter clinical trial using intracoronary multimodal physiology
In diabetic patients a predisposed coronary microcirculation along with a higher risk of distal particulate embolization during primary percutaneous intervention (PCI) increases the risk of peri-procedural mic... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 19, 2017 Category: Cardiology Authors: Enrico Cerrato, Alicia Quir ós, Mauro Echavarría-Pinto, Hernan Mejia-Renteria, Andres Aldazabal, Nicola Ryan, Nieves Gonzalo, Pilar Jimenez-Quevedo, Luis Nombela-Franco, Pablo Salinas, Iván J. Núñez-Gil, José Ramón Rumoroso, Antonio Fernández-Orti Source Type: research

The use of lipid-lowering therapy and effects of antihyperglycaemic therapy on lipids in subjects with type 2 diabetes with or without cardiovascular disease: a pooled analysis of data from eleven randomized trials with insulin glargine 100  U/mL
This study aimed to characterize the extent of lipid-lowering therapy use and i... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 19, 2017 Category: Cardiology Authors: Markolf Hanefeld, Louise Traylor, Ling Gao and Wolfgang Landgraf Source Type: research

Effects of exenatide on cardiac function, perfusion, and energetics in type 2 diabetic patients with cardiomyopathy: a randomized controlled trial against insulin glargine
Multiple bloodglucose-lowering agents have been linked to cardiovascular events. Preliminary studies showed improvement in left ventricular (LV) function during glucagon-like peptide-1 receptor agonist adminis... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 19, 2017 Category: Cardiology Authors: Weena J. Y. Chen, Michaela Diamant, Karin de Boer, Hendrik J. Harms, Lourens F. H. J. Robbers, Albert C. van Rossum, Mark H. H. Kramer, Adriaan A. Lammertsma and Paul Knaapen Source Type: research

SGLT2 inhibitors: a novel choice for the combination therapy in diabetic kidney disease
Diabetic kidney disease (DKD) is the most common cause of end stage renal disease. The comprehensive management of DKD depends on combined target-therapies for hyperglycemia, hypertension, albuminuria, and hyp... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 16, 2017 Category: Cardiology Authors: Honghong Zou, Baoqin Zhou and Gaosi Xu Source Type: research

Target organ damage and incident type 2 diabetes mellitus: the Strong Heart Study
Recent analyses in a registry of hypertensive patients suggested that preceding left ventricular (LV) hypertrophy (LVH) and/or carotid atherosclerosis are associated with incident type 2 diabetes, independent ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 12, 2017 Category: Cardiology Authors: Giovanni de Simone, Wenyu Wang, Lyle G. Best, Fawn Yeh, Raffaele Izzo, Costantino Mancusi, Mary J. Roman, Elisa T. Lee, Barbara V. Howard and Richard B. Devereux Source Type: research

Effect of sitagliptin on the echocardiographic parameters of left ventricular diastolic function in patients with type 2 diabetes: a subgroup analysis of the PROLOGUE study
Diabetes is associated closely with an increased risk of cardiovascular events, including diastolic dysfunction and heart failure that leads to a shortening of life expectancy. It is therefore extremely valuab... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 11, 2017 Category: Cardiology Authors: Hirotsugu Yamada, Atsushi Tanaka, Kenya Kusunose, Rie Amano, Munehide Matsuhisa, Hiroyuki Daida, Masaaki Ito, Hiroyuki Tsutsui, Mamoru Nanasato, Haruo Kamiya, Yasuko K. Bando, Masato Odawara, Hisako Yoshida, Toyoaki Murohara, Masataka Sata and Koichi Node Source Type: research

Lipopolysaccharide-binding protein is associated with arterial stiffness in patients with type 2 diabetes: a cross-sectional study
Lipopolysaccharide (LPS)-binding protein (LBP) is an acute-phase reactant that mediates immune responses triggered by LPS. Recent evidence indicates the association of circulating LBP levels with obesity, diab... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 10, 2017 Category: Cardiology Authors: Takeshi Sakura, Tomoaki Morioka, Atsushi Shioi, Yoshinori Kakutani, Yuya Miki, Yuko Yamazaki, Koka Motoyama, Katsuhito Mori, Shinya Fukumoto, Tetsuo Shoji, Masanori Emoto and Masaaki Inaba Source Type: research

Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice
Diastolic dysfunction (DD), a hallmark of obesity and primary defect in heart failure with preserved ejection fraction, is a predictor of future cardiovascular events. We previously reported that linagliptin, ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 5, 2017 Category: Cardiology Authors: Annayya R. Aroor, Javad Habibi, Hemanth Kumar Kandikattu, Mona Garro-Kacher, Brady Barron, Dongqing Chen, Melvin R. Hayden, Adam Whaley-Connell, Shawn B. Bender, Thomas Klein, Jaume Padilla, James R. Sowers, Bysani Chandrasekar and Vincent G. DeMarco Source Type: research

Erratum to: Inhibition of dynamin-related protein 1 protects against myocardial ischemia –reperfusion injury in diabetic mice
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 4, 2017 Category: Cardiology Authors: Mingge Ding, Qianqian Dong, Zhenhua Liu, Zheng Liu, Yinxian Qu, Xing Li, Cong Huo, Xin Jia, Feng Fu and Xiaoming Wang Source Type: research

Erratum to: Third generation drug eluting stent (DES) with biodegradable polymer in diabetic patients: 5  years follow-up
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 4, 2017 Category: Cardiology Authors: Marcus Wiemer, Sinisa Stojkovic, Alexander Samol, Zisis Dimitriadis, Juan M. Ruiz-Nodar, Ralf Birkemeyer, Jacques Monsegu, G érard Finet, David Hildick-Smith, Damras Tresukosol, Enrique Garcia Novo, Jacques J. Koolen, Emanuele Barbato and Gian Battista D Source Type: research

Erratum to: Inhibition of dynamin-related protein 1 protects against myocardial ischemia –reperfusion injury in diabetic mice
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 4, 2017 Category: Cardiology Authors: Mingge Ding, Qianqian Dong, Zhenhua Liu, Zheng Liu, Yinxian Qu, Xing Li, Cong Huo, Xin Jia, Feng Fu and Xiaoming Wang Source Type: research

Erratum to: Third generation drug eluting stent (DES) with biodegradable polymer in diabetic patients: 5  years follow-up
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 4, 2017 Category: Cardiology Authors: Marcus Wiemer, Sinisa Stojkovic, Alexander Samol, Zisis Dimitriadis, Juan M. Ruiz-Nodar, Ralf Birkemeyer, Jacques Monsegu, G érard Finet, David Hildick-Smith, Damras Tresukosol, Enrique Garcia Novo, Jacques J. Koolen, Emanuele Barbato and Gian Battista D Source Type: research

Erratum to: Higher serum betatrophin level in type 2 diabetes subjects is associated with urinary albumin excretion and renal function
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 26, 2017 Category: Cardiology Authors: Chang-Chiang Chen, Hendra Susanto, Wen-Han Chuang, Ta-Yu Liu, Arivajiagane Arundhathi and Chih-Hong Wang Source Type: research

Retinal vessel diameters and reactivity in diabetes mellitus and/or cardiovascular disease
Retinal vessel calibre and vascular dilation/constriction in response to flicker light provocation may provide a measure distinguishing patients suffering from diabetes mellitus and/or cardiovascular disease. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 26, 2017 Category: Cardiology Authors: R. Heitmar, G. Y. H. Lip, R. E. Ryder and A. D. Blann Source Type: research

Remote ischemic preconditioning differentially attenuates post-ischemic cardiac arrhythmia in streptozotocin-induced diabetic versus nondiabetic rats
Sudden cardiac death (SCD), a leading cause of global mortality, most commonly arises from a substrate of cardiac ischemia, but requires an additional trigger. Diabetes mellitus (DM) predisposes to SCD even af... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 26, 2017 Category: Cardiology Authors: Zhaoyang Hu, Mou Chen, Ping Zhang, Jin Liu and Geoffrey W. Abbott Source Type: research

Erratum to: Higher serum betatrophin level in type 2 diabetes subjects is associated with urinary albumin excretion and renal function
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 26, 2017 Category: Cardiology Authors: Chang-Chiang Chen, Hendra Susanto, Wen-Han Chuang, Ta-Yu Liu, Arivajiagane Arundhathi and Chih-Hong Wang Source Type: research

Plasma matrix metalloproteinases are associated with incident cardiovascular disease and all-cause mortality in patients with type 1 diabetes: a 12-year follow-up study
Altered regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to vascular complications in type 1 diabetes. We invest... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 26, 2017 Category: Cardiology Authors: S. A. Peeters, L. Engelen, J. Buijs, A. Jorsal, H.-H. Parving, L. Tarnow, P. Rossing, C. G. Schalkwijk and C. D. A. Stehouwer Source Type: research

Anatomic fat depots and cardiovascular risk: a focus on the leg fat using nationwide surveys (KNHANES 2008 –2011)
Although central fat is a well-known risk factor for cardiovascular disease (CVD) and cardiometabolic disorders, the effect of other regional fats or muscle distribution on CVD risk has not been fully investig... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 26, 2017 Category: Cardiology Authors: Eugene Han, Yong-ho Lee, Byung-Wan Lee, Eun Seok Kang, In-Kyu Lee and Bong-Soo Cha Source Type: research

Erratum to: Obesity and type 2 diabetes have additive effects on left ventricular remodelling in normotensive patients-a cross sectional study
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 20, 2017 Category: Cardiology Authors: Kirstie A. De Jong, Juliane K. Czeczor, Smithamol Sithara, Kevin McEwen, Gary D. Lopaschuk, Alan Appelbe, Kimberly Cukier, Mark Kotowicz and Sean L. McGee Source Type: research

Advanced glycation end-products decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells
Advanced glycation end-products (AGEs) are elevated under diabetic conditions and associated with insulin resistance, endothelial dysfunction and vascular inflammation in humans. It has been demonstrated that ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 20, 2017 Category: Cardiology Authors: Xiaomei Ren, Liqun Ren, Qin Wei, Hua Shao, Long Chen and Naifeng Liu Source Type: research

Is ischemia the only factor predicting cardiovascular outcomes in all diabetes mellitus patients?
Diabetes mellitus (DM) is associated with an excess in cardiovascular morbidity and mortality, and is characterized by increased rates of coronary artery disease. Furthermore, once atherosclerosis is establish... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 20, 2017 Category: Cardiology Authors: Mark W. Kennedy, Enrico Fabris, Harry Suryapranata and Elvin Kedhi Source Type: research

Treatment with high-dose n-3 PUFAs has no effect on platelet function, coagulation, metabolic status or inflammation in patients with atherosclerosis and type 2 diabetes
Despite numerous studies on cardioprotective effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs), there is limited evidence for n-3 PUFA-mediated effects, especially at its higher dose, on cardiovascula... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 14, 2017 Category: Cardiology Authors: Malgorzata Poreba, Magdalena Mostowik, Aleksander Siniarski, Renata Golebiowska-Wiatrak, Krzysztof Piotr Malinowski, Maciej Haberka, Ewa Konduracka, Jadwiga Nessler, Anetta Undas and Grzegorz Gajos Source Type: research

Subclinical inflammation associated with prolonged TIMP-1 upregulation and arterial stiffness after gestational diabetes mellitus: a hospital-based cohort study
Gestational diabetes mellitus (GDM) has significant implications for the future health of the mother. Some clinical studies have suggested subclinical inflammation and vascular dysfunction after GDM. We aimed ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 13, 2017 Category: Cardiology Authors: Tiina Vilmi-Ker älä, Anneli Lauhio, Taina Tervahartiala, Outi Palomäki, Jukka Uotila, Timo Sorsa and Ari Palomäki Source Type: research

Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial
Type 2 diabetes mellitus (T2DM) is characterized by systemic metabolic abnormalities and the development of micro- and macrovascular complications, resulting in a shortened life expectancy. A recent cardiovasc... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 12, 2017 Category: Cardiology Authors: Atsushi Tanaka, Michio Shimabukuro, Yosuke Okada, Isao Taguchi, Minako Yamaoka-Tojo, Hirofumi Tomiyama, Hiroki Teragawa, Seigo Sugiyama, Hisako Yoshida, Yasunori Sato, Atsushi Kawaguchi, Yumi Ikehara, Noritaka Machii, Tatsuya Maruhashi, Kosuke R. Shima, T Source Type: research

Human serum RNase-L level is inversely associated with metabolic syndrome and age
Ribonuclease-L (RNase-L) was known to be a ubiquitous enzyme involved in several cellular functions, especially innate immunity. It was recently shown to participate in adipogenesis in rodents. Here, we develo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 11, 2017 Category: Cardiology Authors: Yi-Ting Wang, Ping-Huei Tseng, Chi-Ling Chen, Der-Sheng Han, Yu-Chiao Chi, Fen-Yu Tseng and Wei-Shiung Yang Source Type: research

Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats
Disturbances in coronary microcirculatory function, such as the endothelial glycocalyx, are early hallmarks in the development of obesity and insulin resistance. Accordingly, in the present study myocardial mi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 11, 2017 Category: Cardiology Authors: Judith van Haare, M. Eline Kooi, Jurgen W. G. E. van Teeffelen, Hans Vink, Jos Slenter, Hanneke Cobelens, Gustav J. Strijkers, Dennis Koehn, Mark J. Post and Marc van Bilsen Source Type: research

Pregnancy-associated plasma protein-A is a stronger predictor for adverse cardiovascular outcomes after acute coronary syndrome in type-2 diabetes mellitus
The risk prediction of pregnancy-associated plasma protein-A (PAPP-A) for future cardiovascular (CV) events post acute coronary syndrome (ACS) in patients with type-2 diabetes mellitus (T2DM) was investigated ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 5, 2017 Category: Cardiology Authors: Wei-Ping Li, Moni B. Neradilek, Fu-Sheng Gu, Daniel A. Isquith, Zhi-Jun Sun, Xing Wu, Hong-Wei Li and Xue-Qiao Zhao Source Type: research