Association of serum Cyr61 levels with peripheral arterial disease in subjects with type 2 diabetes
The prevalence of peripheral artery disease (PAD) is obviously increased in patients with diabetes. Existing evidence shows that cysteine-rich angiogenic inducer 61 (Cyr61), a 40-kD secreted protein, plays imp... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 22, 2020 Category: Cardiology Authors: Bin Feng, Guidong Xu, Kangyun Sun, Kaipeng Duan, Bimin Shi and Nannan Zhang Tags: Original investigation Source Type: research

Risk for cardiovascular disease associated with metabolic syndrome and its components: a 13-year prospective study in the RIVANA cohort
We aimed to investigate the association of metabolic syndrome (MetS) and its single components with cardiovascular risk and estimated their impact on the prematurity of occurrence of cardiovascular events usin... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 22, 2020 Category: Cardiology Authors: Mar ía J. Guembe, Cesar I. Fernandez-Lazaro, Carmen Sayon-Orea, Estefanía Toledo and Conchi Moreno-Iribas Tags: Original investigation Source Type: research

Renoprotection with SGLT2 inhibitors in type 2 diabetes over a spectrum of cardiovascular and renal risk
Approximately half of all patients with type 2 diabetes (T2D) develop a certain degree of renal impairment. In many of them, chronic kidney disease (CKD) progresses over time, eventually leading to end-stage k... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 22, 2020 Category: Cardiology Authors: Francesco Giorgino, Jiten Vora, Peter Fenici and Anna Solini Tags: Review Source Type: research

Prevalence of readily detected amyloid blood clots in ‘unclotted’ Type 2 Diabetes Mellitus and COVID-19 plasma: a preliminary report
Type 2 Diabetes Mellitus (T2DM) is a well-known comorbidity to COVID-19 and coagulopathies are a common accompaniment to both T2DM and COVID-19. In addition, patients with COVID-19 are known to develop micro-c... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 17, 2020 Category: Cardiology Authors: Etheresia Pretorius, Chantelle Venter, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp and Douglas B. Kell Tags: Original investigation Source Type: research

Prognostic irrelevance of plaque vulnerability following plaque sealing in high-risk patients with type 2 diabetes: an optical coherence tomography study
Type 2 diabetes mellitus (T2DM) is associated with an increased cardiovascular risk related at least in part to a more vulnerable plaque phenotype. However, patients with T2DM exhibit also an increased risk fo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 12, 2020 Category: Cardiology Authors: Rosalia Dettori, Andrea Milzi, Kathrin Burgmaier, Mohammad Almalla, Martin Hellmich, Nikolaus Marx, Sebastian Reith and Mathias Burgmaier Tags: Original investigation Source Type: research

Cholesterol lowering therapies and achievement of targets for primary and secondary cardiovascular prevention in type 2 diabetes: unmet needs in a large population of outpatients at specialist clinics
The well-established benefit of Low-Dense-Lipoprotein-cholesterol (LDL-c) lowering treatments (LLTs) has led clinical guidelines to lower the cardiovascular prevention targets. Despite this, there is a surpris... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 10, 2020 Category: Cardiology Authors: Mario Luca Morieri, Angelo Avogaro and Gian Paolo Fadini Tags: Original investigation Source Type: research

Body mass index and cardiovascular outcomes in patients with acute coronary syndrome by diabetes status: the obesity paradox in a Korean national cohort study
The “obesity paradox” has not been elucidated in the long-term outcomes of acute coronary syndrome (ACS). We investigated the association between obesity and cardiovascular (CV) outcomes in ACS patients with a... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 10, 2020 Category: Cardiology Authors: Se-Jun Park, Kyoung Hwa Ha and Dae Jung Kim Tags: Original investigation Source Type: research

Sodium-glucose cotransporter 2 inhibitor versus metformin as first-line therapy in patients with type 2 diabetes mellitus: a multi-institution database study
Sodium-glucose co-transporter 2 inhibitors (SGLT2i) has shown evidence of cardiovascular benefit in patients with type 2 diabetes mellitus (T2DM). Currently metformin is the guideline-recommended first-line tr... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 9, 2020 Category: Cardiology Authors: Tien-Hsing Chen, Yan-Rong Li, Shao-Wei Chen, Yu-Sheng Lin, Chi-Chin Sun, Dong-Yi Chen, Chun-Tai Mao, Michael Wu, Chih-Hsiang Chang, Pao-Hsien Chu and Victor Chien-Chia Wu Tags: Original investigation Source Type: research

The risk of new-onset atrial fibrillation in patients with type 2 diabetes mellitus treated with sodium glucose cotransporter 2 inhibitors versus dipeptidyl peptidase-4 inhibitors
Sodium glucose cotransporter 2 inhibitor (SGLT2i) reduces the risk of hard cardiovascular endpoints in type 2 diabetes mellitus (T2DM) patients with/without established cardiovascular diseases. Whether SGLT2i ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 6, 2020 Category: Cardiology Authors: Ann Wan-Chin Ling, Cze-Ci Chan, Shao-Wei Chen, Yi-Wei Kao, Chien-Ying Huang, Yi-Hsin Chan and Pao-Hsien Chu Tags: Original investigation Source Type: research

Depression and cardiovascular risk —association among Beck Depression Inventory, PCSK9 levels and insulin resistance
Depression and cardiovascular disease (CVD) are among the most common causes of disability in high-income countries, depression being associated with a 30% increased risk of future CV events. Depression is twi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 3, 2020 Category: Cardiology Authors: C. Macchi, C. Favero, A. Ceresa, L. Vigna, D. M. Conti, A. C. Pesatori, G. Racagni, A. Corsini, N. Ferri, C. R. Sirtori, M. Buoli, V. Bollati and M. Ruscica Tags: Original investigation Source Type: research

Serum alkaline phosphatase levels and the risk of new-onset diabetes in hypertensive adults
The association between alkaline phosphatase (ALP) and incident diabetes remains uncertain. Our study aimed to investigate the prospective relation of serum ALP with the risk of new-onset diabetes, and explore... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 24, 2020 Category: Cardiology Authors: Yuanyuan Zhang, Chun Zhou, Jianping Li, Yan Zhang, Di Xie, Min Liang, Binyan Wang, Yun Song, Xiaobin Wang, Yong Huo, Fan Fan Hou, Xiping Xu and Xianhui Qin Tags: Original investigation Source Type: research

Worldwide inertia to the use of cardiorenal protective glucose-lowering drugs (SGLT2i and GLP-1 RA) in high-risk patients with type 2 diabetes
The disclosure of proven cardiorenal benefits with certain antidiabetic agents was supposed to herald a new era in the management of type 2 diabetes (T2D), especially for the many patients with T2D who are at ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 23, 2020 Category: Cardiology Authors: Guntram Schernthaner, Naim Shehadeh, Alexander S. Ametov, Anna V. Bazarova, Fahim Ebrahimi, Peter Fasching, Andrej Jane ž, Péter Kempler, Ilze Konrāde, Nebojša M. Lalić, Boris Mankovsky, Emil Martinka, Dario Rahelić, Cristian Serafinceanu, Jan Škrh Tags: Commentary Source Type: research

Distinct non-ischemic myocardial late gadolinium enhancement lesions in patients with type 2 diabetes
Cardiovascular magnetic resonance imaging (CMR) have described localised non-ischemic late gadolinium enhancement (LGE) lesions of prognostic importance in various non-ischemic cardiomyopathies. Ischemic LGE l... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 22, 2020 Category: Cardiology Authors: Annemie Stege Bojer, Martin Heyn S ørensen, Niels Vejlstrup, Jens P. Goetze, Peter Gæde and Per Lav Madsen Tags: Original investigation Source Type: research

Global trend of diabetes mortality attributed to vascular complications, 2000 –2016
The global epidemic of diabetes mellitus continues to grow and affects developed and developing countries alike. Intensive glycemic control is thought to modify the risks for vascular complications, hence the ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 20, 2020 Category: Cardiology Authors: Wei Ling, Yi Huang, Yan-Mei Huang, Rong-Rong Fan, Yi Sui and Hai-Lu Zhao Tags: Original investigation Source Type: research

Prognostic impact of admission high-sensitivity C-reactive protein in acute myocardial infarction patients with and without diabetes mellitus
High-sensitivity C-reactive protein (hs-CRP) elevation frequently occurs in acute myocardial infarction (AMI) and is associated with adverse outcomes. Since diabetes mellitus (DM) is characterized by an underl... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 20, 2020 Category: Cardiology Authors: Claudia Lucci, Nicola Cosentino, Stefano Genovese, Jeness Campodonico, Valentina Milazzo, Monica De Metrio, Maurizio Rondinelli, Daniela Riggio, Maria Luisa Biondi, Mara Rubino, Katia Celentano, Alice Bonomi, Nicol ò Capra, Fabrizio Veglia, Piergiuseppe Tags: Original investigation Source Type: research

Blood pressure levels and cardiovascular risk according to age in patients with diabetes mellitus: a nationwide population-based cohort study
Little is known about age-specific target blood pressure (BP) in hypertensive patients with diabetes mellitus (DM). The aim of this study was to determine the BP level at the lowest cardiovascular risk of hype... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 19, 2020 Category: Cardiology Authors: Hack-Lyoung Kim, Hyue Mee Kim, Chang Hee Kwon, Jeong-Hun Shin, Mi-Hyang Jung, Chan Joo Lee, Dae-Hee Kim, Woo-Hyeun Kim, Si-Hyuck Kang, Ju-Hee Lee, In Jeong Cho, Iksung Cho, Jun Hyeok Lee, Dae Ryong Kang, Hae-Young Lee, Wook-Jin Chung & hellip; Tags: Original investigation Source Type: research

Associations of cardiac stress biomarkers with incident type 2 diabetes and changes in glucose metabolism: KORA F4/FF4 study
High N-terminal pro-brain-type natriuretic peptide levels have been associated with a lower risk of type 2 diabetes mellitus (T2D). However, less is known about other cardiac stress biomarkers in this context.... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 16, 2020 Category: Cardiology Authors: Chaterina Sujana, Jochen Seissler, Jens Jordan, Wolfgang Rathmann, Wolfgang Koenig, Michael Roden, Ulrich Mansmann, Christian Herder, Annette Peters, Barbara Thorand and Cornelia Then Tags: Original investigation Source Type: research

Ticagrelor monotherapy in patients with concomitant diabetes mellitus and chronic kidney disease: a post hoc analysis of the GLOBAL LEADERS trial
Patients with both diabetes mellitus (DM) and chronic kidney disease (CKD) are a subpopulation characterized by ultrahigh ischemic and bleeding risk after percutaneous coronary intervention. There are limited ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 16, 2020 Category: Cardiology Authors: Chao Gao, Mariusz Tomaniak, Kuniaki Takahashi, Hideyuki Kawashima, Rutao Wang, Hironori Hara, Masafumi Ono, Gilles Montalescot, Scot Garg, Michael Haude, Ton Slagboom, Pascal Vranckx, Marco Valgimigli, Stephan Windecker, Robert-Jan van Geuns, Christian Ha Tags: Original investigation Source Type: research

MR-proANP and incident cardiovascular disease in patients with type 2 diabetes with and without heart failure with preserved ejection fraction
Mid-regional pro-atrial natriuretic peptide (MR-proANP) is a useful biomarker in outpatients with type 2 diabetes (T2D) to diagnose heart failure (HF). Elevated B-type natriuretic peptides are included in the ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 16, 2020 Category: Cardiology Authors: Jesper Jensen, Morten Schou, Caroline Kistorp, Jens Faber, Tine W. Hansen, Magnus T. Jensen, Henrik U. Andersen, Peter Rossing, Tina Vilsb øll and Peter G. Jørgensen Tags: Original investigation Source Type: research

Incidence of idiopathic cardiomyopathy in patients with type 2 diabetes in Taiwan: age, sex, and urbanization status-stratified analysis
The epidemiology of diabetes and idiopathic cardiomyopathy have limited data. We investigated the overall and the age-, sex-, and urbanization-specific incidence and relative hazard of idiopathic cardiomyopath... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 14, 2020 Category: Cardiology Authors: Hua-Fen Chen, Ya-Hui Chang, Hsien-Jung Lo, Muhammad Atoillah Isfandiari, Santi Martini, Wen-Hsuan Hou and Chung-Yi Li Tags: Original investigation Source Type: research

Empagliflozin reduced long-term HbA1c variability and cardiovascular death: insights from the EMPA-REG OUTCOME trial
Glucose variability has been associated with cardiovascular outcomes in type 2 diabetes, however, the interplay between glucose variability, empagliflozin and cardiovascular death has not been explored. In the... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 13, 2020 Category: Cardiology Authors: Antonio Ceriello, Anne Pernille Ofstad, Isabella Zwiener, Stefan Kaspers, Jyothis George and Antonio Nicolucci Tags: Original investigation Source Type: research

Blood pressure and mortality in patients with type 2 diabetes and a recent coronary event in the ELIXA trial
The relationship between blood pressure and mortality in type 2 diabetes (T2DM) is controversial, with concern for increased risk associated with excessively lowered blood pressure. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 12, 2020 Category: Cardiology Authors: Magnus O. Wijkman, Brian Claggett, Rafael Diaz, Hertzel C. Gerstein, Lars K øber, Eldrin Lewis, Aldo P. Maggioni, Emil Wolsk, David Aguilar, Rhonda Bentley-Lewis, John J. McMurray, Jeffrey Probstfield, Matthew Riddle, Jean-Claude Tardif, Scott D. Solomon Tags: Original investigation Source Type: research

Cardiovascular risks and bleeding with non-vitamin K antagonist oral anticoagulant versus warfarin in patients with type 2 diabetes: a tapered matching cohort study
We compared the risk of bleeding and cardiovascular disease (CVD) events between non-vitamin K antagonist oral anticoagulant (NOAC) and warfarin in people with type 2 diabetes (T2DM). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 10, 2020 Category: Cardiology Authors: Dahai Yu, Zhanzheng Zhao and David Simmons Tags: Original investigation Source Type: research

High glycated albumin is an independent predictor of low response to clopidogrel in ACS patients: a cross-sectional study
Glycated albumin (GA) is a marker of short-term glycemic control and is strongly associated with the occurrence of diabetes. Previous studies have shown an association between GA and the effect of clopidogrel ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 9, 2020 Category: Cardiology Authors: Xiliang Zhao, Quan Li, Chenchen Tu, Yong Zeng and Yicong Ye Tags: Original investigation Source Type: research

Comparative effectiveness of dulaglutide versus liraglutide in Asian type 2 diabetes patients: a multi-institutional cohort study and meta-analysis
This study was aimed to assess the real-world comparative effectiveness of dulaglutide versus liraglutide. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 9, 2020 Category: Cardiology Authors: Kai-Cheng Chang, Shih-Chieh Shao, Shihchen Kuo, Chen-Yi Yang, Hui-Yu Chen, Yuk-Ying Chan and Huang-Tz Ou Tags: Original investigation Source Type: research

Use of the ankle-brachial index combined with the percentage of mean arterial pressure at the ankle to improve prediction of all-cause mortality in type 2 diabetes mellitus: an observational study
Peripheral artery disease (PAD) in the lower extremities is a common complication of type 2 diabetes and has been shown to be associated with mortality. The ankle-brachial index (ABI) is a simple noninvasive m... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 9, 2020 Category: Cardiology Authors: Yu-Hsuan Li, Wayne Huey-Herng Sheu and I-Te Lee Tags: Original investigation Source Type: research

Impact of combined training with different exercise intensities on inflammatory and lipid markers in type 2 diabetes: a secondary analysis from a 1-year randomized controlled trial
Exercise is a well-accepted strategy to improve lipid and inflammatory profile in individuals with type 2 diabetes (T2DM). However, the exercise intensity having the most benefits on lipids and inflammatory ma... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 7, 2020 Category: Cardiology Authors: Jo ão P. Magalhães, Diana A. Santos, Inês R. Correia, Megan Hetherington-Rauth, Rogério Ribeiro, João F. Raposo, Andreia Matos, Manuel D. Bicho and Luís B. Sardinha Tags: Original investigation Source Type: research

Association between omentin-1 and major cardiovascular events after lower extremity endovascular revascularization in diabetic patients: a prospective cohort study
Cardiovascular complications represent the major cause of morbidity and mortality of type 2 diabetes mellitus (T2DM) patients. In particular, peripheral artery disease (PAD) represents a frequent T2DM vascular... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 7, 2020 Category: Cardiology Authors: Federico Biscetti, Elisabetta Nardella, Maria Margherita Rando, Andrea Leonardo Cecchini, Flavia Angelini, Alessandro Cina, Roberto Iezzi, Marco Filipponi, Angelo Santoliquido, Dario Pitocco, Raffaele Landolfi and Andrea Flex Tags: Original investigation Source Type: research

Association of circulating PCSK9 concentration with cardiovascular metabolic markers and outcomes in stable coronary artery disease patients with or without diabetes: a prospective, observational cohort study
Whether plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) levels is a predictor for cardiovascular outcomes has currently been controversial. No data is currently available regarding the relation of... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 6, 2020 Category: Cardiology Authors: Jia Peng, Ming-Ming Liu, Jing-Lu Jin, Ye-Xuan Cao, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Qian Dong, Jing Sun, Rui-Xia Xu and Jian-Jun Li Tags: Original investigation Source Type: research

Adolescent BMI and early-onset type 2 diabetes among Ethiopian immigrants and their descendants: a nationwide study
We assessed in a nationwide cohort the association between adolescent BMI and early-onset ( (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 6, 2020 Category: Cardiology Authors: Maya Simchoni, Uri Hamiel, Orit Pinhas-Hamiel, Inbar Zucker, Tali Cukierman-Yaffe, Miri Lutski, Estela Derazne, Zivan Beer, Doron Behar, Lital Keinan-Boker, Ofri Mosenzon, Dorit Tzur, Arnon Afek, Amir Tirosh, Itamar Raz and Gilad Twig Tags: Original investigation Source Type: research

Evaluation of cardiovascular risk in adults with type 1 diabetes: poor concordance between the 2019 ESC risk classification and 10-year cardiovascular risk prediction according to the Steno Type 1 Risk Engine
Patients with type 1 diabetes (T1D) have higher mortality risk compared to the general population; this is largely due to increased rates of cardiovascular disease (CVD). As accurate CVD risk stratification is... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 3, 2020 Category: Cardiology Authors: Nicola Tecce, Maria Masulli, Roberta Lupoli, Giuseppe Della Pepa, Lutgarda Bozzetto, Luisa Palmisano, Angela Albarosa Rivellese, Gabriele Riccardi and Brunella Capaldo Tags: Original investigation Source Type: research

Everolimus-eluting bioresorbable scaffolds and metallic stents in diabetic patients: a patient-level pooled analysis of the prospective ABSORB DM Benelux Study, TWENTE and DUTCH PEERS
Several studies compared everolimus-eluting bioresorbable scaffolds (EE-BRS) with everolimus-eluting stents (EES), but only few assessed these devices in patients with diabetes mellitus. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 2, 2020 Category: Cardiology Authors: T. M. Hommels, R. S. Hermanides, B. Berta, E. Fabris, G. De Luca, E. H. Ploumen, C. von Birgelen and E. Kedhi Tags: Original investigation Source Type: research

Clinical outcome of biodegradable polymer sirolimus-eluting stent and durable polymer everolimus-eluting stent in patients with diabetes
Diabetes mellitus is a risk for increased incidence of adverse clinical events after percutaneous coronary intervention. However, the difference in the incidence of adverse clinical events according to stent t... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 1, 2020 Category: Cardiology Authors: Ryota Kakizaki, Yoshiyasu Minami, Masahiro Katamine, Aritomo Katsura, Yusuke Muramatsu, Takuya Hashimoto, Kentaro Meguro, Takao Shimohama and Junya Ako Tags: Original investigation Source Type: research

Left atrial strain and diastolic function abnormalities in obese and type 2 diabetic adolescents and young adults
Adults with obesity and type 2 diabetes mellitus (T2DM) related to obesity are at increased risk of heart failure with preserved ejection fraction (HFpEF). Whether left ventricular (LV) diastolic function abno... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 1, 2020 Category: Cardiology Authors: Jeremy M. Steele, Elaine M. Urbina, Wojciech M. Mazur, Philip R. Khoury, Sherif F. Nagueh, Justin T. Tretter and Tarek Alsaied Tags: Original investigation Source Type: research

Cardiometabolic multimorbidity is associated with a worse Covid-19 prognosis than individual cardiometabolic risk factors: a multicentre retrospective study (CoViDiab II)
Cardiometabolic disorders may worsen Covid-19 outcomes. We investigated features and Covid-19 outcomes for patients with or without diabetes, and with or without cardiometabolic multimorbidity. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 1, 2020 Category: Cardiology Authors: Ernesto Maddaloni, Luca D ’Onofrio, Francesco Alessandri, Carmen Mignogna, Gaetano Leto, Giuseppe Pascarella, Ivano Mezzaroma, Miriam Lichtner, Paolo Pozzilli, Felice Eugenio Agrò, Monica Rocco, Francesco Pugliese, Andrea Lenzi, Rury R. Holman, Claudio Tags: Original investigation Source Type: research

Effects of semaglutide on risk of cardiovascular events across a continuum of cardiovascular risk: combined post hoc analysis of the SUSTAIN and PIONEER trials
Semaglutide is a glucagon-like peptide-1 (GLP-1) analog treatment for type 2 diabetes (T2D) available in subcutaneous (s.c.) and oral formulations. Two cardiovascular (CV) outcomes trials showed that in subjec... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 30, 2020 Category: Cardiology Authors: Mansoor Husain, Stephen C. Bain, Anders Gaarsdal Holst, Thomas Mark, S øren Rasmussen and Ildiko Lingvay Tags: Original investigation Source Type: research

Chronic kidney disease and undiagnosed atrial fibrillation in individuals with diabetes
Diabetes is an independent risk factor for atrial fibrillation (AF), which is associated with increases in mortality and morbidity, as well as a diminished quality of life. Renal involvement in diabetes is com... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 30, 2020 Category: Cardiology Authors: Nam Ju Heo, Sang Youl Rhee, Jill Waalen and Steven Steinhubl Tags: Original investigation Source Type: research

Fibroblast growth factor-23 is associated with imaging markers of diabetic cardiomyopathy and anti-diabetic therapeutics
The biomarker fibroblast growth factor-23 (FGF-23) has been associated with increased cardiovascular morbidity and mortality in both patients with and without type 2 diabetes. The aim of this study was to eval... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 30, 2020 Category: Cardiology Authors: Martin H. S ørensen, Annemie S. Bojer, Niklas R. Jørgensen, David A. Broadbent, Sven Plein, Per L. Madsen and Peter Gæde Tags: Original investigation Source Type: research

Characterization of left ventricular myocardial sodium-glucose cotransporter 1 expression in patients with end-stage heart failure
Whereas selective sodium-glucose cotransporter 2 (SGLT2) inhibitors consistently showed cardiovascular protective effects in large outcome trials independent of the presence of type 2 diabetes mellitus (T2DM),... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 30, 2020 Category: Cardiology Authors: Alex Ali Sayour, Attila Ol áh, Mihály Ruppert, Bálint András Barta, Eszter Mária Horváth, Kálmán Benke, Miklós Pólos, István Hartyánszky, Béla Merkely and Tamás Radovits Tags: Original investigation Source Type: research

Major adverse cardiovascular and limb events in patients with diabetes and concomitant peripheral artery disease treated with sodium glucose cotransporter 2 inhibitor versus dipeptidyl peptidase-4 inhibitor
Whether sodium glucose co-transporter 2 inhibitors (SGLT2i) are associated with a lower risk of cardiovascular as well as adverse lower limb events in patients with type-2 diabetes mellitus (T2DM) and concomit... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 30, 2020 Category: Cardiology Authors: Hsin-Fu Lee, Shao-Wei Chen, Jia-Rou Liu, Pei-Ru Li, Lung-Sheng Wu, Shang-Hung Chang, Yung-Hsin Yeh, Chi-Tai Kuo, Yi-Hsin Chan and Lai-Chu See Tags: Original investigation Source Type: research

The impact of triglyceride-glucose index on incident cardiovascular events during 16 years of follow-up: Tehran Lipid and Glucose Study
To investigate whether the Triglyceride-Glucose index (TyG-index) is associated with increased risk of cardiovascular diseases (CVD)/coronary heart disease (CHD). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 29, 2020 Category: Cardiology Authors: Niloofar Barzegar, Maryam Tohidi, Mitra Hasheminia, Fereidoun Azizi and Farzad Hadaegh Tags: Original investigation Source Type: research

Exposure-weighted scoring for metabolic syndrome and the risk of myocardial infarction and stroke: a nationwide population-based study
Metabolic syndrome (MetS) status changes over time, but few studies have investigated the relationship between the extent or duration of exposure to MetS and the risk of cardiovascular disease (CVD). We invest... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 29, 2020 Category: Cardiology Authors: Eun Young Lee, Kyungdo Han, Da Hye Kim, Yong-Moon Park, Hyuk-Sang Kwon, Kun-Ho Yoon, Mee Kyoung Kim and Seung-Hwan Lee Tags: Original investigation Source Type: research

Heterogeneity of antidiabetic treatment effect on the risk of major adverse cardiovascular events in type 2 diabetes: a systematic review and meta-analysis
We explored whether clinically relevant baseline characteristics of patients with type 2 diabetes can modify the effect of glucagon-like peptide-1 receptor agonists (GLP-1 RA) or sodium-glucose cotransporter-2... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 29, 2020 Category: Cardiology Authors: Elvira D ’Andrea, Aaron S. Kesselheim, Jessica M. Franklin, Emily H. Jung, Spencer Phillips Hey and Elisabetta Patorno Tags: Original investigation Source Type: research

Long-term prognostic utility of low-density lipoprotein (LDL) triglyceride in real-world patients with coronary artery disease and diabetes or prediabetes
Recent guidelines highlighted the association between atherosclerosis and triglyceride-enriched lipoproteins in patients with impaired glucose metabolism. However, evidence from prospective studies for long-te... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 27, 2020 Category: Cardiology Authors: Jing-Lu Jin, Hui-Wen Zhang, Ye-Xuan Cao, Hui-Hui Liu, Qi Hua, Yan-Fang Li, Yan Zhang, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Rui-Xia Xu, Ying Gao, Xiao-Lin Li, Chuan-Jue Cui, Geng Liu, Jing Sun & hellip; Tags: Original investigation Source Type: research

Combination therapy with pemafibrate (K-877) and pitavastatin improves vascular endothelial dysfunction in dahl/salt-sensitive rats fed a high-salt and high-fat diet
Statins suppress the progression of atherosclerosis by reducing low-density lipoprotein (LDL) cholesterol levels. Pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor α modulator, ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 26, 2020 Category: Cardiology Authors: Masatoki Yoshida, Kazufumi Nakamura, Toru Miyoshi, Masashi Yoshida, Megumi Kondo, Kaoru Akazawa, Tomonari Kimura, Hiroaki Ohtsuka, Yuko Ohno, Daiji Miura and Hiroshi Ito Tags: Original investigation Source Type: research

Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial
Metformin has been shown to have both neuroprotective and neurodegenerative effects. The aim of this study was to investigate the effect of metformin in combination with insulin on cardiovascular autonomic neu... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 26, 2020 Category: Cardiology Authors: Christian Stevns Hansen, Louise Lundby-Christiansen, Lise Tarnow, Christian Gluud, Christoffer Hedetoft, Birger Thorsteinsson, Bianca Hemmingsen, Niels Wiinberg, Simone B. Sneppen, S øren S. Lund, Thure Krarup, Sten Madsbad, Thomas Almdal, Bendix Carsten Tags: Original investigation Source Type: research

Diabetes as a risk factor for incident peripheral arterial disease in women compared to men: a systematic review and meta-analysis
Previous meta-analyses have suggested that diabetes confers a greater excess risk of coronary heart disease, stroke, vascular dementia, and heart failure in women compared to men. While the underlying mechanis... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 26, 2020 Category: Cardiology Authors: Alyssa Z. Chase-Vilchez, Isaac H. Y. Chan, Sanne A. E. Peters and Mark Woodward Tags: Review Source Type: research

Impact of long-term glucose variability on coronary atherosclerosis progression in patients with type 2 diabetes: a 2.3 year follow-up study
In this study, we aimed to investigate whether long-term GV has an impact on coronary atherosclerosis progression in patients with type 2 diab... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 25, 2020 Category: Cardiology Authors: Suhua Li, Xixiang Tang, Yanting Luo, Bingyuan Wu, Zhuoshan Huang, Zexiong Li, Long Peng, Yesheng Ling, Jieming Zhu, Junlin Zhong, Jinlai Liu and Yanming Chen Tags: Original investigation Source Type: research

Sortilin levels correlate with major cardiovascular events of diabetic patients with peripheral artery disease following revascularization: a prospective study
Peripheral artery disease (PAD) represents one of the most relevant vascular complications of type 2 diabetes mellitus (T2DM). Moreover, T2DM patients suffering from PAD have an increased risk of major adverse... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 25, 2020 Category: Cardiology Authors: Federico Biscetti, Elisabetta Nardella, Maria Margherita Rando, Andrea Leonardo Cecchini, Nicola Bonadia, Piergiorgio Bruno, Flavia Angelini, Carmine Di Stasi, Andrea Contegiacomo, Angelo Santoliquido, Dario Pitocco, Raffaele Landolfi and Andrea Flex Tags: Original investigation Source Type: research

Effects of empagliflozin versus placebo on cardiac sympathetic activity in acute myocardial infarction patients with type 2 diabetes mellitus: the EMBODY trial
Protection from lethal ventricular arrhythmias leading to sudden cardiac death (SCD) is a crucial challenge after acute myocardial infarction (AMI). Cardiac sympathetic and parasympathetic activity can be noni... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 25, 2020 Category: Cardiology Authors: Wataru Shimizu, Yoshiaki Kubota, Yu Hoshika, Kosuke Mozawa, Shuhei Tara, Yukichi Tokita, Kenji Yodogawa, Yu-ki Iwasaki, Takeshi Yamamoto, Hitoshi Takano, Yayoi Tsukada, Kuniya Asai, Masaaki Miyamoto, Yasushi Miyauchi, Eitaro Kodani, Masahiro Ishikawa & he Tags: Original investigation Source Type: research