Effect of empagliflozin on ectopic fat stores and myocardial energetics in type 2 diabetes: the EMPACEF study
Empagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that has demonstrated cardiovascular and renal protection in patients with type 2 diabetes (T2D). We hypothesized that empaglifozin (EMPA) co... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - March 1, 2021 Category: Cardiology Authors: B. Gaborit, P. Ancel, A. E. Abdullah, F. Maurice, I. Abdesselam, A. Calen, A. Soghomonian, M. Houssays, I. Varlet, M. Eisinger, A. Lasbleiz, F. Peiretti, C. E. Bornet, Y. Lefur, L. Pini, S. Rapacchi & hellip; Tags: Original investigation Source Type: research

Risk for recurrent cardiovascular disease events among patients with diabetes and chronic kidney disease
Adults who have experienced multiple cardiovascular disease (CVD) events have a very high risk for additional events. Diabetes and chronic kidney disease (CKD) are each associated with an increased risk for re... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - March 1, 2021 Category: Cardiology Authors: Demetria Hubbard, Lisandro D. Colantonio, Robert S. Rosenson, Todd M. Brown, Elizabeth A. Jackson, Lei Huang, Kate K. Orroth, Stephanie Reading, Mark Woodward, Vera Bittner, Orlando M. Gutierrez, Monika M. Safford, Michael E. Farkouh and Paul Muntner Tags: Original investigation Source Type: research

Traditional and non-traditional risk factors for peripheral artery disease development/progression in patients with type 2 diabetes: the Rio de Janeiro type 2 diabetes cohort study
The prognostic importance of non-traditional risk factors for peripheral artery disease (PAD) development/progression is scarcely studied in diabetes. We investigated if carotid intima-media thickness (CIMT) a... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 27, 2021 Category: Cardiology Authors: Claudia R. L. Cardoso, Juliana V. Melo, Thain á R. M. Santos, Nathalie C. Leite and Gil F. Salles Tags: Original investigation Source Type: research

MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics
The epidemic of diabetes mellitus (DM) necessitates the development of novel therapeutic and preventative strategies to attenuate complications of this debilitating disease. Diabetic cardiomyopathy (DCM) is a ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 27, 2021 Category: Cardiology Authors: Daniel Jakubik, Alex Fitas, Ceren Eyileten, Joanna Jarosz-Popek, Anna Nowak, Pamela Czajka, Zofia Wicik, Harald Sourij, Jolanta M. Siller-Matula, Salvatore De Rosa and Marek Postula Tags: Review Source Type: research

Clinical and metabolomic predictors of regression to normoglycemia in a population at intermediate cardiometabolic risk
Impaired fasting glucose (IFG) is a prevalent and potentially reversible intermediate stage leading to type 2 diabetes that increases risk for cardiometabolic complications. The identification of clinical and ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 27, 2021 Category: Cardiology Authors: Magdalena del Roc ío Sevilla-González, Jordi Merino, Hortensia Moreno-Macias, Rosalba Rojas-Martínez, Donají Verónica Gómez-Velasco and Alisa K. Manning Tags: Original investigation Source Type: research

Thromboembolism, bleeding and vascular death in nonvalvular atrial fibrillation patients with type 2 diabetes receiving rivaroxaban or warfarin
Diabetes increases a patient ’s risk of developing atrial fibrillation by 49%. Patients with nonvalvular atrial fibrillation are at a fivefold increased risk of stroke and die more frequently from vascular caus... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 26, 2021 Category: Cardiology Authors: Craig I. Coleman, Olivia S. Costa, Christopher W. Brescia, Burcu Vardar, Khaled Abdelgawwad and Nitesh Sood Tags: Original investigation Source Type: research

Correction to: Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet ‑induced obese rats
An amendment to this paper has been published and can be accessed via the original article. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 26, 2021 Category: Cardiology Authors: Judith van Haare, M. Eline Kooi, Jurgen W. G. E. van Teeffelen, Hans Vink, Jos Slenter, Hanneke Cobelens, Gustav J. Strijkers, Dennis Koehn, Mark J. Post and Marc van Bilsen Tags: Correction Source Type: research

Activation of the cardiac non-neuronal cholinergic system prevents the development of diabetes-associated cardiovascular complications
Acetylcholine (ACh) plays a crucial role in the function of the heart. Recent evidence suggests that cardiomyocytes possess a non-neuronal cholinergic system (NNCS) that comprises of choline acetyltransferase ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 22, 2021 Category: Cardiology Authors: Eng Leng Saw, James T. Pearson, Daryl O. Schwenke, Pujika Emani Munasinghe, Hirotsugu Tsuchimochi, Shruti Rawal, Sean Coffey, Philip Davis, Richard Bunton, Isabelle Van Hout, Yuko Kai, Michael J. A. Williams, Yoshihiko Kakinuma, Martin Fronius and Rajesh Tags: Original investigation Source Type: research

Correction to: Early impairment of coronary microvascular perfusion capacity in rats on a high fat diet
An amendment to this paper has been published and can be accessed via the original article. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 22, 2021 Category: Cardiology Authors: Judith van Haare, M. Eline Kooi, Hans Vink, Mark J. Post, Jurgen W. G. E. van Teeffelen, Jos Slenter, Chantal Munts, Hanneke Cobelens, Gustav J. Strijkers, Dennis Koehn and Marc van Bilsen Tags: Correction Source Type: research

Diabetic phenotype and prognosis of patients with heart failure and preserved ejection fraction in a real life cohort
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome, with several underlying etiologic and pathophysiologic factors. The presence of diabetes might identify an important phenotyp... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 19, 2021 Category: Cardiology Authors: Sibille Lejeune, Clotilde Roy, Alisson Slimani, Agn ès Pasquet, David Vancraeynest, Jean-Louis Vanoverschelde, Bernhard L. Gerber, Christophe Beauloye and Anne-Catherine Pouleur Tags: Original investigation Source Type: research

Prognostic value of soluble suppression of tumorigenesis-2 (sST2) for cardiovascular events in coronary artery disease patients with and without diabetes mellitus
Soluble suppression of tumorigenesis-2 (sST2) is implicated in myocardial overload and has long been recognized as an inflammatory marker related to heart failure and acute coronary syndrome, but data on the p... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 19, 2021 Category: Cardiology Authors: Man Li, Lei Duan, Yulun Cai, Benchuan Hao, Jianqiao Chen, Huiying Li and Hongbin Liu Tags: Original investigation Source Type: research

Triglyceride-glucose index and the risk of stroke and its subtypes in the general population: an 11-year follow-up
Triglyceride-glucose (TyG) index was recently suggested to be a reliable surrogate marker of insulin resistance. We aim to investigate the associations between baseline and long-term TyG index with subsequent ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 18, 2021 Category: Cardiology Authors: Anxin Wang, Guangyao Wang, Qian Liu, Yingting Zuo, Shuohua Chen, Boni Tao, Xue Tian, Penglian Wang, Xia Meng, Shouling Wu, Yongjun Wang and Yilong Wang Tags: Original investigation Source Type: research

Plasma fibrin clot properties and cardiovascular mortality in patients with type 2 diabetes: a long ‐term follow‐up study
Patients with type 2 diabetes mellitus (T2DM) are at high risk of cardiovascular mortality, but the mechanisms behind this remain unclear. Prothrombotic fibrin clot properties have been shown in T2DM and cardi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 18, 2021 Category: Cardiology Authors: Agata Hanna Bryk, Ma łgorzata Konieczyńska, Maciej Polak, Dariusz Plicner, Maciej Bochenek and Anetta Undas Tags: Original investigation Source Type: research

Role of Canagliflozin on function of CD34+ve endothelial progenitor cells (EPC) in patients with type 2 diabetes
Endothelial progenitor cells (EPCs) has been shown to be dysfunctional in both type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) leading to poor regeneration of endothelium and renal perfusion. ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 13, 2021 Category: Cardiology Authors: Seshagiri Rao Nandula, Nabanita Kundu, Hassan B. Awal, Beda Brichacek, Mona Fakhri, Nikhila Aimalla, Adrian Elzarki, Richard L. Amdur and Sabyasachi Sen Tags: Original investigation Source Type: research

The predictive utility of circulating PCSK9 levels on diabetes mellitus
Increasing data including ours have suggested that proprotein convertase subtilisin/kexin type 9 (PCSK9), a novel regulator of cholesterol metabolism, may also play an important role in the development of type... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 13, 2021 Category: Cardiology Authors: Jia Peng, Cheng-Gang Zhu and Jian-Jun Li Tags: Commentary Source Type: research

SGLT-2 inhibitors and atrial fibrillation in the Food and Drug Administration adverse event reporting system
We examined the association between SGLT2i and AF in the Food an... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 11, 2021 Category: Cardiology Authors: Benedetta Maria Bonora, Emanuel Raschi, Angelo Avogaro and Gian Paolo Fadini Tags: Original investigation Source Type: research

Prognostic significance of diabetes mellitus in patients with atrial fibrillation
There are limited data on the association of diabetes mellitus (DM) and levels of glycated hemoglobin (HbA1c) with outcomes in patients with atrial fibrillation (AF). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 11, 2021 Category: Cardiology Authors: Andreas S. Papazoglou, Anastasios Kartas, Athanasios Samaras, Ioannis Vouloagkas, Eleni Vrana, Dimitrios V. Moysidis, Evangelos Akrivos, Georgios Kotzampasis, Amalia Baroutidou, Anastasios Papanastasiou, Evangelos Liampas, Michail Botis, Efstratios Karagi Tags: Original investigation Source Type: research

Cardiovascular surrogate markers and cardiometabolic therapeutics: a viewpoint learned from clinical trials on dipeptidyl peptidase-4 inhibitors
This study platform... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 11, 2021 Category: Cardiology Authors: Atsushi Tanaka and Koichi Node Tags: Commentary Source Type: research

Treatment strategies in patients with diabetes and three ‐vessel coronary disease: What should we choose?
The recent study demonstrating that percutaneous coronary intervention and coronary artery bypass grafting were associated with a lower risk of death and major adverse cardiac and cerebrovascular events (compo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 11, 2021 Category: Cardiology Authors: Bo Liang and Ning Gu Tags: Commentary Source Type: research

Predictive effect of triglyceride ‑glucose index on clinical events in patients with type 2 diabetes mellitus and acute myocardial infarction: results from an observational cohort study in China
Triglyceride glucose (TyG) index is considered a reliable alternative marker of insulin resistance and an independent predictor of cardiovascular (CV) outcomes. However, the prognostic value of TyG index in pa... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 11, 2021 Category: Cardiology Authors: Yue Zhang, Xiaosong Ding, Bing Hua, Qingbo Liu, Hui Gao, Hui Chen, Xue-Qiao Zhao, Weiping Li and Hongwei Li Tags: Original investigation Source Type: research

Epicardial adipose tissue volume and coronary calcification among people living with diabetes: a cross-sectional study
Epicardial adipose tissue (EAT) has anatomic and functional proximity to the heart and is considered a novel diagnostic marker and therapeutic target in cardiometabolic diseases. The aim of this study was to e... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 5, 2021 Category: Cardiology Authors: Emmanuel Cosson, Minh Tuan Nguyen, Imen Rezgani, Sopio Tatulashvili, Meriem Sal, Narimane Berkane, Lucie Allard, Pierre-Yves Brillet and H élène Bihan Tags: Original investigation Source Type: research

The residual cardiorenal risk in type 2 diabetes
In this commentary, we introduce the concepts of removed and residual risks in conditioning thecardiorenal outlook of patients with type 2 diabetes (T2D). The removed cardiorenal risk represents the risk of pr... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 5, 2021 Category: Cardiology Authors: Dario Giugliano, Maria Ida Maiorino, Giuseppe Bellastella and Katherine Esposito Tags: Commentary Source Type: research

Correction to: Impact of a 2 ‑year trial of nutritional ketosis on indices of cardiovascular disease risk in patients with type 2 diabetes
An amendment to this paper has been published and can be accessed via the original article. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 5, 2021 Category: Cardiology Authors: Shaminie J. Athinarayanan, Sarah J. Hallberg, Amy L. McKenzie, Katharina Lechner, Sarah King, James P. McCarter, Jeff S. Volek, Stephen D. Phinney and Ronald M. Krauss Tags: Correction Source Type: research

A prospective randomized study comparing effects of empagliflozin to sitagliptin on cardiac fat accumulation, cardiac function, and cardiac metabolism in patients with early-stage type 2 diabetes: the ASSET study
While the cardioprotective benefits of sodium-glucose cotransporter-2 (SGLT2) inhibitors have been established in patients with cardiovascular disease (CVD), their advantages over other anti-diabetic drugs at ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 2, 2021 Category: Cardiology Authors: Shigenori Hiruma, Fumika Shigiyama, Shinji Hisatake, Sunao Mizumura, Nobuyuki Shiraga, Masaaki Hori, Takanori Ikeda, Takahisa Hirose and Naoki Kumashiro Tags: Original investigation Source Type: research

Hyperglycemia, inflammatory response and infarct size in obstructive acute myocardial infarction and MINOCA
Hyperglycemia has been associated with increased inflammatory indexes and larger infarct sizes in patients with obstructive acute myocardial infarction (obs-AMI). In contrast, no studies have explored these co... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 2, 2021 Category: Cardiology Authors: Pasquale Paolisso, Alberto Fo à, Luca Bergamaschi, Francesco Donati, Michele Fabrizio, Chiara Chiti, Francesco Angeli, Sebastiano Toniolo, Andrea Stefanizzi, Matteo Armillotta, Paola Rucci, Gianmarco Iannopollo, Gianni Casella, Cinzia Marrozzini, Nazzare Tags: Original investigation Source Type: research

Performance of the recommended ESC/EASD cardiovascular risk stratification model in comparison to SCORE and NT-proBNP as a single biomarker for risk prediction in type 2 diabetes mellitus
Recently, the European Society of Cardiology (ESC) and European Association for the Society of Diabetes (EASD) introduced a new cardiovascular disease (CVD) risk stratification model to aid further treatment d... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - February 2, 2021 Category: Cardiology Authors: Suriya Prausm üller, Michael Resl, Henrike Arfsten, Georg Spinka, Raphael Wurm, Stephanie Neuhold, Philipp E. Bartko, Georg Goliasch, Guido Strunk, Noemi Pavo, Martin Clodi and Martin Hülsmann Tags: Original investigation Source Type: research

Independent association of atherogenic dyslipidaemia with all ‐cause mortality in individuals with type 2 diabetes and modifying effect of gender: a prospective cohort study
Atherogenic dyslipidaemia has been implicated in the residual risk for cardiovascular morbidity and mortality, which remains despite attainment of LDL cholesterol goals especially in individuals with type 2 di... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 30, 2021 Category: Cardiology Authors: Emanuela Orsi, Giuseppe Penno, Anna Solini, Enzo Bonora, Cecilia Fondelli, Roberto Trevisan, Monica Vedovato, Franco Cavalot, Susanna Morano, Marco G. Baroni, Antonio Nicolucci and Giuseppe Pugliese Tags: Original investigation Source Type: research

Long-term prognosis of chronic total occlusion treated by successful percutaneous coronary intervention in patients with or without diabetes mellitus: a systematic review and meta-analysis
Diabetes mellitus (DM) is highly prevalent among patients undergoing percutaneous coronary intervention (PCI) for chronic total occlusion (CTO). Therefore, the purpose of our study was to investigate the clini... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 30, 2021 Category: Cardiology Authors: Yong Zhu, Shuai Meng, Maolin Chen, Kesen Liu, Ruofei Jia, Hong Li, Huagang Zhu and Zening Jin Tags: Original investigation Source Type: research

Association of metformin monotherapy or combined therapy with cardiovascular risks in patients with type 2 diabetes mellitus
Metformin is a first-line drug in type 2 diabetes mellitus (T2DM) treatment, yet whether metformin may increase all-cause or cardiovascular mortality of T2DM patients remains inconclusive. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 30, 2021 Category: Cardiology Authors: Tian Li, Rui Providencia, Nan Mu, Yue Yin, Mai Chen, Yishi Wang, Manling Liu, Lu Yu, Chunhu Gu and Heng Ma Tags: Original investigation Source Type: research

Correction to: Long ‑term outcomes of medical therapy versus successful recanalisation for coronary chronic total occlusions in patients with and without type 2 diabetes mellitus
An amendment to this paper has been published and can be accessed via the original article. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 30, 2021 Category: Cardiology Authors: Lei Guo, Junjie Wang, Huaiyu Ding, Shaoke Meng, Xiaoyan Zhang, Haichen Lv, Lei Zhong, Jian Wu, Jiaying Xu, Xuchen Zhou and Rongchong Huang Tags: Correction Source Type: research

Metabolic syndrome, fatty liver, and artificial intelligence-based epicardial adipose tissue measures predict long-term risk of cardiac events: a prospective study
We sought to evaluate the association of metabolic syndrome (MetS) and computed tomography (CT)-derived cardiometabolic biomarkers (non-alcoholic fatty liver disease [NAFLD] and epicardial adipose tissue [EAT]... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 29, 2021 Category: Cardiology Authors: Andrew Lin, Nathan D. Wong, Aryabod Razipour, Priscilla A. McElhinney, Frederic Commandeur, Sebastien J. Cadet, Heidi Gransar, Xi Chen, Stephanie Cantu, Robert J. H. Miller, Nitesh Nerlekar, Dennis T. L. Wong, Piotr J. Slomka, Alan Rozanski, Balaji K. Tam Tags: Original investigation Source Type: research

Effect of sodium –glucose cotransporter 2 inhibitors on cardiac structure and function in type 2 diabetes mellitus patients with or without chronic heart failure: a meta-analysis
Although the benefits of sodium –glucose cotransporter 2 inhibitors (SGLT2i) on cardiovascular events have been reported in patients with type 2 diabetes mellitus (T2DM) with or without heart failure (HF), the ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 25, 2021 Category: Cardiology Authors: Yi-Wen Yu, Xue-Mei Zhao, Yun-Hong Wang, Qiong Zhou, Yan Huang, Mei Zhai and Jian Zhang Tags: Review Source Type: research

Association of pericardial adipose tissue with left ventricular structure and function: a region ‐specific effect?
This study aimed to determine whether PAT is associated with left ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 25, 2021 Category: Cardiology Authors: Jin-Seok Kim, Seon Won Kim, Jong Seok Lee, Seung Ku Lee, Robert Abbott, Ki Yeol Lee, Hong Euy Lim, Ki-Chul Sung, Goo-Yeong Cho, Kwang Kon Koh, Sun H. Kim, Chol Shin and Seong Hwan Kim Tags: Original investigation Source Type: research

Sex, age, type of diabetes and incidence of atrial fibrillation in patients with diabetes mellitus: a nationwide analysis
There remain uncertainties regarding diabetes mellitus and the incidence of atrial fibrillation (AF), in relation to type of diabetes, and the interactions with sex and age. We investigated whether diabetes co... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 22, 2021 Category: Cardiology Authors: Arnaud Bisson, Alexandre Bodin, Gr égoire Fauchier, Julien Herbert, Denis Angoulvant, Pierre Henri Ducluzeau, Gregory Y. H. Lip and Laurent Fauchier Tags: Original investigation Source Type: research

Impact of insulin resistance on subclinical left ventricular dysfunction in normal weight and overweight/obese japanese subjects in a general community
Insulin resistance carries increased risk of heart failure, although the pathophysiological mechanisms remain unclear. LV global longitudinal strain (LVGLS) assessed by speckle-tracking echocardiography has em... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 21, 2021 Category: Cardiology Authors: Kazutoshi Hirose, Koki Nakanishi, Masao Daimon, Naoko Sawada, Yuriko Yoshida, Kentaro Iwama, Yuko Yamamoto, Jumpei Ishiwata, Megumi Hirokawa, Katsuhiro Koyama, Tomoko Nakao, Hiroyuki Morita, Marco R. Di Tullio, Shunichi Homma and Issei Komuro Tags: Original investigation Source Type: research

Ten-year cardiovascular risk in diabetes patients without obstructive coronary artery disease: a retrospective Western Denmark cohort study
Diabetes patients without obstructive coronary artery disease as assessed by coronary angiography have a low risk of myocardial infarction, but their myocardial infarction risk may still be higher than the gen... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 21, 2021 Category: Cardiology Authors: Kevin Kris Warnakula Olesen, Morten Madsen, Christine Gyldenkerne, Pernille Gro Thrane, Troels Thim, Lisette Okkels Jensen, Hans Erik B øtker, Henrik Toft Sørensen and Michael Maeng Tags: Original investigation Source Type: research

Cumulative burden of metabolic syndrome and its components on the risk of atrial fibrillation: a nationwide population-based study
The metabolic syndrome (MetS) and its components are associated with the development of atrial fibrillation (AF). However, the impact of time-burden of MetS on the risk of AF is unknown. We investigated the ef... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 19, 2021 Category: Cardiology Authors: Hyo-Jeong Ahn, Kyung-Do Han, Eue-Keun Choi, Jin-Hyung Jung, Soonil Kwon, So-Ryoung Lee, Seil Oh and Gregory Y. H. Lip Tags: Original investigation Source Type: research

Cost-effectiveness of GLP-1 receptor agonists versus insulin for the treatment of type 2 diabetes: a real-world study and systematic review
To conduct a real-word-study-based cost-effectiveness analysis of a GLP-1 receptor agonist (GLP-1RA) versus insulin among type 2 diabetes patients requiring intensified injection therapy and a systematic revie... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 19, 2021 Category: Cardiology Authors: Chen-Yi Yang, Ying-Ren Chen, Huang-Tz Ou and Shihchen Kuo Tags: Original investigation Source Type: research

Reduction in cardiovascular mortality following severe hypoglycemia in individuals with type 2 diabetes: the role of a pragmatic and structured intervention
Mortality in individuals with diabetes with severe hypoglycemia requiring ambulance services intervention is high and it is unclear whether this is modifiable. Our aim was to characterise this high-risk group ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 12, 2021 Category: Cardiology Authors: Sam M. Pearson, Beverley Whittam, Kavita Kulavarasalingam, Amelia Mitchell-Gears, Cathyrn James and Ramzi A. Ajjan Tags: Original investigation Source Type: research

Triglyceride –glucose index is associated with the risk of myocardial infarction: an 11-year prospective study in the Kailuan cohort
The triglyceride –glucose (TyG) index, which is a simple surrogate marker of insulin resistance, has been suggested as a contributor of cardiovascular disease. However, evidence on the effect of long-term eleva... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 12, 2021 Category: Cardiology Authors: Xue Tian, Yingting Zuo, Shuohua Chen, Qian Liu, Boni Tao, Shouling Wu and Anxin Wang Tags: Original investigation Source Type: research

Real-world outcomes of different treatment strategies in patients with diabetes and three-vessel coronary disease: a mean follow-up 6.3 years study from China
Patients with diabetes and triple-vessel disease (TVD) are associated with a high risk of events. The choice of treatment strategies remains a subject of discussion. In the real-world, we aim to compare the ou... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 11, 2021 Category: Cardiology Authors: Xueyan Zhao, Lianjun Xu, Lin Jiang, Jian Tian, Yin Zhang, Dong Wang, Kai Sun, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Lei Song and Jinqing Yuan Tags: Original investigation Source Type: research

Sodium –glucose transporter-2 inhibitors for prevention and treatment of cardiorenal complications of type 2 diabetes
Hospitalization for major diabetes complications, including myocardial infarction, stroke, lower-extremity amputation, and end-stage kidney disease, is on the rise and represents a great health burden for pati... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 11, 2021 Category: Cardiology Authors: Dario Giugliano, Miriam Longo, Lorenzo Scappaticcio, Paola Caruso and Katherine Esposito Tags: Review Source Type: research

Dual SGLT-1 and SGLT-2 inhibition improves left atrial dysfunction in HFpEF
Sodium –glucose linked transporter type 2 (SGLT-2) inhibition has been shown to reduce cardiovascular mortality in heart failure independently of glycemic control and prevents the onset of atrial arrhythmias, a... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 7, 2021 Category: Cardiology Authors: David Bode, Lukas Semmler, Paulina Wakula, Niklas Hegemann, Uwe Primessnig, Nicola Beindorff, David Powell, Raphael Dahmen, Hartmut Ruetten, Christian Oeing, Alessio Alogna, Daniel Messroghli, Burkert M. Pieske, Frank R. Heinzel and Felix Hohendanner Tags: Original investigation Source Type: research

Comprehensive elaboration of glycemic variability in diabetic macrovascular and microvascular complications
Diabetes mellitus is the major risk factor for the development of macrovascular and microvascular complications. It is increasingly recognized that glycemic variability (GV), referring to oscillations in blood... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 7, 2021 Category: Cardiology Authors: Bao Sun, Zhiying Luo and Jiecan Zhou Tags: Review Source Type: research

The additive effects of kidney dysfunction on left ventricular function and strain in type 2 diabetes mellitus patients verified by cardiac magnetic resonance imaging
Patients with type 2 diabetes mellitus (T2DM) are susceptible to coexisted with chronic kidney disease (CKD), which may increase cardiovascular mortality in these patients. The present study aimed to verify wh... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 7, 2021 Category: Cardiology Authors: Yi Zhang, Jin Wang, Yan Ren, Wei-feng Yan, Li Jiang, Yuan Li and Zhi-gang Yang Tags: Original investigation Source Type: research

Effects of liraglutide on diastolic function parameters in patients with type 2 diabetes and coronary artery disease: a randomized crossover study
Diastolic dysfunction is highly prevalent in patients with type 2 diabetes mellitus (T2DM) and is associated with overweight, glucose dysregulation and coronary artery disease (CAD). The GLP-1 receptor agonist... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 7, 2021 Category: Cardiology Authors: Preman Kumarathurai, Ahmad Sajadieh, Christian Anholm, Ole P. Kristiansen, Steen B. Haugaard and Olav W. Nielsen Tags: Original investigation Source Type: research

Apabetalone and hospitalization for heart failure in patients following an acute coronary syndrome: a prespecified analysis of the BETonMACE study
Patients with diabetes and acute coronary syndrome (ACS) are at high risk for subsequent heart failure. Apabetalone is a selective inhibitor of bromodomain and extra-terminal (BET) proteins, epigenetic regulat... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 7, 2021 Category: Cardiology Authors: Stephen J. Nicholls, Gregory G. Schwartz, Kevin A. Buhr, Henry N. Ginsberg, Jan O. Johansson, Kamyar Kalantar-Zadeh, Ewelina Kulikowski, Peter P. Toth, Norman Wong, Michael Sweeney and Kausik K. Ray Tags: Original investigation Source Type: research

Association between the Mediterranean lifestyle, metabolic syndrome and mortality: a whole-country cohort in Spain
Evidence is limited about the joint health effects of the Mediterranean lifestyle on cardiometabolic health and mortality. The aim of this study was to evaluate the association of the Mediterranean lifestyle w... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 5, 2021 Category: Cardiology Authors: Mercedes Sotos-Prieto, Rosario Ortol á, Miguel Ruiz-Canela, Esther Garcia-Esquinas, David Martínez-Gómez, Esther Lopez-Garcia, Miguel Ángel Martínez-González and Fernando Rodriguez-Artalejo Tags: Original investigation Source Type: research

Efficacy of dulaglutide on vascular health indexes in subjects with type 2 diabetes: a randomized trial
Recent cardiovascular outcome trials have shown significant reductions in major cardiovascular (CV) events with glucagon-like peptide (GLP)-1 receptor agonists. Additionally, adjunctive surrogates for cardiova... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 4, 2021 Category: Cardiology Authors: Antonino Tuttolomondo, Anna Cirrincione, Alessandra Casuccio, Alessandro Del Cuore, Mario Daidone, Tiziana Di Chiara, Domenico Di Raimondo, Vittoriano Della Corte, Carlo Maida, Irene Simonetta, Stefania Scaglione and Antonio Pinto Tags: Original investigation Source Type: research

Impact of peroxisome proliferator-activated receptor- α on diabetic cardiomyopathy
The prevalence of cardiomyopathy is higher in diabetic patients than those without diabetes. Diabetic cardiomyopathy (DCM) is defined as a clinical condition of abnormal myocardial structure and performance in... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 4, 2021 Category: Cardiology Authors: Lin Wang, Yin Cai, Liguo Jian, Chi Wai Cheung, Liangqing Zhang and Zhengyuan Xia Tags: Review Source Type: research