Relationship between sarcopenia and fatty liver in middle-aged and elderly patients with type 2 diabetes mellitus
In this study, we investigated the relationship between sarcopenia and fatty liver in middle-aged and elderly patients diagnosed with type 2 diabetes mellitus (T2DM) to provide a theoretical foundation for the... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - April 20, 2024 Category: Orthopaedics Authors: Li Quan, Fang Zhang, Jing Xu, Fei Wang and Yong Fan Tags: Research article Source Type: research

Metabolic and Skeletal Characterization of the KK/Ay Mouse Model —A Polygenic Mutation Model of Obese Type 2 Diabetes
AbstractType 2 diabetes (T2D) increases fracture incidence and fracture-related mortality rates (KK.Cg-Ay/J. The Jackson Laboratory; Available from:https://www.jax.org/strain/002468). While numerous mouse models for T2D exist, few effectively stimulate persistent hyperglycemia in both sexes, and even fewer are suitable for bone studies. Commonly used models like db/db and ob/ob have altered leptin pathways, confounding bone-related findings since leptin regulates bone properties (Fajardo et al. in Journal of Bone and Mineral Research 29(5): 1025 –1040, 2014). The Yellow Kuo Kondo (KK/Ay) mouse, a polygenic mutation model...
Source: Calcified Tissue International - April 20, 2024 Category: Orthopaedics Source Type: research

Real-World Effectiveness of the Gla-300  + Cap + App Program in Adult Users Living with Type 2 Diabetes in Taiwan
ConclusionsUse of digital technology within a connected ecosystem such as Gla-300  + Cap + App program could help people with type 2 diabetes to improve their glycemic condition. (Source: Diabetes Therapy)
Source: Diabetes Therapy - April 20, 2024 Category: Endocrinology Source Type: research

Relationship between indices of insulin resistance and incident type 2 diabetes mellitus in Chinese adults
ConclusionTG/HDL-c, TyG, and TyG –BMI index were all significantly positively associated with higher risk for future T2DM. Baseline TyG–BMI level had high predictive value for the identification of T2DM. (Source: Endocrine)
Source: Endocrine - April 20, 2024 Category: Endocrinology Source Type: research

Urinary sphingolipids in adolescents and young adults with youth-onset diabetes
ConclusionUrinary sphingolipids are elevated in adolescents and young adults with youth-onset diabetes and correlate with ACR. Urinary sphingolipids may therefore represent an early biomarker of DKD.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - April 19, 2024 Category: Urology & Nephrology Source Type: research

Kidney biopsy findings in children with diabetes mellitus
ConclusionsWe confirm that changes better known in adults with either type 1 or type 2 diabetes mellitus can occur in children with type 1 diabetes mellitus: overt diabetic nephropathy either on its own or combined with other conditions and kidney disorders other than diabetic nephropathy.Graphical abstractA higher resolution version of the Graphical abstract is available asSupplementary information (Source: Pediatric Nephrology)
Source: Pediatric Nephrology - April 19, 2024 Category: Urology & Nephrology Source Type: research

Fructooligosaccharides Intake during Pregnancy Improves Metabolic Phenotype of Offspring in High Fat Diet ‐Induced Obese Mice
ConclusionThe findings highlight the link between the maternal gut environment and the developmental origin of metabolic syndrome in offspring. These results open novel research avenues into preemptive therapies for metabolic disorders by targeting the maternal gut microbiota. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 19, 2024 Category: Food Science Authors: Junki Miyamoto, Yuna Ando, Akari Nishida, Mayu Yamano, Shunsuke Suzuki, Hiromi Takada, Ikuo Kimura Tags: Research Article Source Type: research

Effect of Nutrition and Behavior Modification Program (NBMP) on maternal and neonatal outcomes among hyperglycemic mothers
CONCLUSIONS: The study's conclusions draw attention to the possible roles that maternal wellness, physical activity, and diet may have in reducing risks for both hyperglycemic mothers and their newborns. The NBMP resulted in higher adherence to lifestyle changes. Further research on a larger sample of hyperglycemic mothers is recommended to expand the generalizability of the findings.PMID:38639514 | DOI:10.26355/eurrev_202404_35903 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 19, 2024 Category: Drugs & Pharmacology Authors: P Premalatha H M A Maha H A Shadia V Krishnaraju K Prabahar N T Mathar Mohideen V Vinoth Prabhu B Prema R M Mashat E L Sampayan A E Hala A A Z Marwa G Kandasamy R Ahmed M A Mervat Source Type: research

The Role of Left Ventricular Pressure-strain Loop in Evaluating Myocardial Work in Patients with Type 2 Diabetes
CONCLUSION: Pressure-strain loop technology can quantitatively, accurately, and sensitively monitor the variations in left ventricular myocardial contractile function of patients with T2D and detect subclinical cardiac injury at an early disease stage.PMID:38639632 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 19, 2024 Category: Complementary Medicine Authors: Xiaoxiao Yin Chao Sun Ruoling Han Juanjuan Li Yue Wen Source Type: research

Copper Deficiency Associated with Glycemic Control in Individuals with Type 2 Diabetes Mellitus
Biol Trace Elem Res. 2024 Apr 19. doi: 10.1007/s12011-024-04185-6. Online ahead of print.ABSTRACTAdequate copper (Cu) status has been associated with improved glycemic control, partly because of its role in reducing oxidative stress through superoxide dismutase (SOD) activity. Thus, the aim was to investigate the relationship between plasma Cu concentration and markers associated with glycemic control in individuals with type 2 diabetes mellitus (T2DM). This observational and cross-sectional study was conducted in individuals with T2DM of both sexes, aged between 19 and 59 years. Plasma Cu levels were analyzed using induct...
Source: Biological Trace Element Research - April 19, 2024 Category: Biology Authors: Matheus Menezes-Santos Beatriz da Cruz Santos Ramara Kadija Fonseca Santos Silv ânio Silvério Lopes da Costa Samir Hip ólito Dos Santos Ana Mara de Oliveira E Silva Vivianne de Sousa Rocha Liliane Viana Pires Source Type: research

Effect of Nutrition and Behavior Modification Program (NBMP) on maternal and neonatal outcomes among hyperglycemic mothers
CONCLUSIONS: The study's conclusions draw attention to the possible roles that maternal wellness, physical activity, and diet may have in reducing risks for both hyperglycemic mothers and their newborns. The NBMP resulted in higher adherence to lifestyle changes. Further research on a larger sample of hyperglycemic mothers is recommended to expand the generalizability of the findings.PMID:38639514 | DOI:10.26355/eurrev_202404_35903 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 19, 2024 Category: Drugs & Pharmacology Authors: P Premalatha H M A Maha H A Shadia V Krishnaraju K Prabahar N T Mathar Mohideen V Vinoth Prabhu B Prema R M Mashat E L Sampayan A E Hala A A Z Marwa G Kandasamy R Ahmed M A Mervat Source Type: research

The Role of Left Ventricular Pressure-strain Loop in Evaluating Myocardial Work in Patients with Type 2 Diabetes
CONCLUSION: Pressure-strain loop technology can quantitatively, accurately, and sensitively monitor the variations in left ventricular myocardial contractile function of patients with T2D and detect subclinical cardiac injury at an early disease stage.PMID:38639632 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 19, 2024 Category: Complementary Medicine Authors: Xiaoxiao Yin Chao Sun Ruoling Han Juanjuan Li Yue Wen Source Type: research

Copper Deficiency Associated with Glycemic Control in Individuals with Type 2 Diabetes Mellitus
Biol Trace Elem Res. 2024 Apr 19. doi: 10.1007/s12011-024-04185-6. Online ahead of print.ABSTRACTAdequate copper (Cu) status has been associated with improved glycemic control, partly because of its role in reducing oxidative stress through superoxide dismutase (SOD) activity. Thus, the aim was to investigate the relationship between plasma Cu concentration and markers associated with glycemic control in individuals with type 2 diabetes mellitus (T2DM). This observational and cross-sectional study was conducted in individuals with T2DM of both sexes, aged between 19 and 59 years. Plasma Cu levels were analyzed using induct...
Source: Biological Trace Element Research - April 19, 2024 Category: Biology Authors: Matheus Menezes-Santos Beatriz da Cruz Santos Ramara Kadija Fonseca Santos Silv ânio Silvério Lopes da Costa Samir Hip ólito Dos Santos Ana Mara de Oliveira E Silva Vivianne de Sousa Rocha Liliane Viana Pires Source Type: research

Diagnostic value of serum FNDC5 and triglyceride glucose index in cardiac dysfunction in patients with type 2 diabetes mellitus
Asian J Surg. 2024 Apr 18:S1015-9584(24)00703-6. doi: 10.1016/j.asjsur.2024.04.043. Online ahead of print.NO ABSTRACTPMID:38641535 | DOI:10.1016/j.asjsur.2024.04.043 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 19, 2024 Category: Surgery Authors: Sulin Yang Source Type: research

Effect of Nutrition and Behavior Modification Program (NBMP) on maternal and neonatal outcomes among hyperglycemic mothers
CONCLUSIONS: The study's conclusions draw attention to the possible roles that maternal wellness, physical activity, and diet may have in reducing risks for both hyperglycemic mothers and their newborns. The NBMP resulted in higher adherence to lifestyle changes. Further research on a larger sample of hyperglycemic mothers is recommended to expand the generalizability of the findings.PMID:38639514 | DOI:10.26355/eurrev_202404_35903 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 19, 2024 Category: Drugs & Pharmacology Authors: P Premalatha H M A Maha H A Shadia V Krishnaraju K Prabahar N T Mathar Mohideen V Vinoth Prabhu B Prema R M Mashat E L Sampayan A E Hala A A Z Marwa G Kandasamy R Ahmed M A Mervat Source Type: research