Editorial Board: Mol. Nutr. Food Res. 2'21
Molecular Nutrition& Food Research, Volume 65, Issue 2, January 2021. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 22, 2021 Category: Food Science Tags: Editorial Board Source Type: research

Front Cover: Yellow Tea Stimulates Thermogenesis in Mice through Heterogeneous Browning of Adipose Tissues
Mol. Nutr. Food Res. 2021,65,2000864DOI:10.1002/mnfr.202000864The yellow tea extract (YTE) enhances adaptive thermogenesis and protects mice from high fat diet induced obesity by modulating adipocyte metabolic conversion. In epididymal adipose tissue, YTE prevents white adipocytes hypertrophy and improves mitochondrial biogenesis. In brown adipose tissue, YTE prevents whitening and induces numerous brown ‐like adipocytes. In subcutaneous adipose tissue, YTE prevents white adipocytes hypertrophy and stimuli beige adipocytes. This is reported by Na Xu, Jun Chu, Rongrong Dong, Fengjuan Lu, Xinfeng Zhang, Min Wang, Ying Shen...
Source: Molecular Nutrition and Food Research - January 22, 2021 Category: Food Science Authors: Na Xu, Jun Chu, Rongrong Dong, Fengjuan Lu, Xinfeng Zhang, Min Wang, Ying Shen, Zhongwen Xie, Chi ‐Tang Ho, Chung S. Yang, Yijun Wang, Xiaochun Wan Tags: Front Cover Source Type: research

Protein Isolates from Raw and Cooked Foxtail Millet Attenuate Development of Type 2 Diabetes in Streptozotocin ‐Induced Diabetic Mice
ConclusionBoth raw and cooked foxtail millet protein isolates can exert hypoglycemic effects in diabetic mice through rewiring glucose homeostasis, mitigating diabetes ‐induced gut dysbiosis, and affecting the GLP‐1R/PI3K/AKT pathway. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 22, 2021 Category: Food Science Authors: Yongxia Fu, Ruiyang Yin, Erhu Guo, Ruhong Cheng, Xianmin Diao, Yong Xue, Qun Shen Tags: Food & Function Source Type: research

Anti ‐Inflammatory Effects of Quercetin on High‐Glucose and Pro‐Inflammatory Cytokine Challenged Vascular Endothelial Cell Metabolism
ConclusionQuercetin was shown to alter the balance of HUVEC metabolites towards a less inflamed phenotype, both alone and in the presence of pro ‐inflammatory stimuli. These changes are consistent with the inhibition of particular enzymes involved in purine metabolism by quercetin and its HUVEC metabolites. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 22, 2021 Category: Food Science Authors: Besim Ozyel, Gw énaëlle Le Gall, Paul W. Needs, Paul A. Kroon Tags: Research Article Source Type: research

Milk and Dairy Products Intake is Related to Cognitive Impairment at Baseline in Predimed Plus Trial
ScopeTo examine the association between milk and dairy products intake and the prevalence of cognitive decline among Spanish individuals at high cardiovascular risk.Methods and resultsCross ‐sectional analyses were performed on baseline data from 6744 adults (aged 55–75 years old). Intake of milk and dairy products was estimated using a food frequency questionnaire grouped into quartiles. The risk of developing cognitive impairment was based on the Mini‐Mental State Examination ( MMSE).We found a higher prevalence of cognitive decline in subjects who consumed more grams. Patients with worse MMSE score (10 –...
Source: Molecular Nutrition and Food Research - January 20, 2021 Category: Food Science Authors: Araceli Mu ñoz Garach, Isabel Cornejo‐Pareja, Miguel Ángel Martínez‐González, Monica Bulló, Dolores Corella, Olga Castañer, Dora Romaguera, Jesús Vioque, Ángel M. Alonso‐Gómez, Julia Wärnberg, J. Alfredo Martínez, Luís Serra Tags: Research Article Source Type: research

The Human Milk Oligosaccharides 3 ‐FL, LNnT, and LDFT Attenuate TNF‐α Induced Inflammation in Fetal Intestinal Epithelial Cells In Vitro Through Shedding or Interacting with TNF Receptor 1
ConclusionOur findings indicate that specific hMO types attenuate TNF ‐α induced inflammation in fetal gut epithelial cells through TNFR1 in a hMO structure‐dependent fashion suggest possibilities to apply hMOs in management of TNF‐α dependent diseases.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 19, 2021 Category: Food Science Authors: Lianghui Cheng, Chunli Kong, Wenjia Wang, Andre Groeneveld, Arjen Nauta, Matthew R. Groves, Mensiena B.G. Kiewiet, Paul Vos Tags: Research Article Source Type: research

Western Diet Aggravated Carbon Tetrachloride ‐Induced Chronic Liver Injury by Disturbing Gut Microbiota and Bile Acid Metabolism
ConclusionWD accelerates the progression of CLD which was associated with changes in the gut microbiota and BA metabolism.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 18, 2021 Category: Food Science Authors: Liya Yang, Yating Li, Shuting Wang, Xiaoyuan Bian, Xianwan Jiang, Jingjing Wu, Kaicen Wang, Qiangqiang Wang, Jiafeng Xia, Shiman Jiang, Aoxiang Zhuge, Yin Yuan, Shenjie Li, Lanjuan Li Tags: Research Article Source Type: research

Pharmacological Therapy Determines the Gut Microbiota Modulation by a Pomegranate Extract Nutraceutical in Metabolic Syndrome: A Randomized Clinical Trial
ConclusionThe prebiotic effect of PE depended on the medication, mainly on HP ‐treatments. Targeting GM could complement MetS therapy, but the patients’ drug therapy should be considered individually.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 18, 2021 Category: Food Science Authors: Adri án Cortés‐Martín, Carlos Eduardo Iglesias‐Aguirre, Amparo Meoro, María Victoria Selma, Juan Carlos Espín Tags: Research Article Source Type: research

Digestive n ‐6 Lipid Oxidation, a Key Trigger of Vascular Dysfunction and Atherosclerosis in the Western Diet: Protective Effects of Apple Polyphenols
Conclusionn ‐6 lipid oxidation during digestion may be a key factor of vascular impairments. Nevertheless, an antioxidant strategy could limit 4‐HNE formation during digestion and thus durably protect vascular function.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 15, 2021 Category: Food Science Authors: Ga ëtan Bolea, Clotilde Philouze, Mathilde Dubois, Sydney Risdon, Anaïs Humberclaude, Christian Ginies, Anne‐Laure Charles, Bernard Geny, Cyril Reboul, Claire Arnaud, Claire Dufour, Grégory Meyer Tags: Research Article Source Type: research

Black Tea Theaflavin Detoxifies Metabolic Toxins in  the Intestinal Tract of Mice
ConclusionTF has the capacity to remove the endogenous metabolic toxins through oxidation, amination, and MGO conjugation in the intestinal tract, which can potentially explain why TF still generates in vivo efficacy while showing a poor systematic bioavailability. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 12, 2021 Category: Food Science Authors: Shuwei Zhang, Christina Ohland, Christian Jobin, Shengmin Sang Tags: Research Article Source Type: research

Digestion and Transport Across the Intestinal Epithelium Affects the Allergenicity of Ara h 1 and 3 but not of Ara h 2 and 6
ConclusionsDigestion and transport influences the allergenicity of Ara h 1 and 3, but not of Ara h 2 and 6. The influence of digestion and transport on protein allergenicity might explain why current in vitro assays are not predictive for allergenicityThis article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 12, 2021 Category: Food Science Authors: Mark Smits, Irene Nooijen, Frank Redegeld, Aard Jong, Thuy ‐My Le, André Knulst, Geert Houben, Kitty Verhoeckx Tags: Research Article Source Type: research

Diet and Inflammatory Bowel Disease – What Quality Standards Should be Applied in Clinical and Laboratory Studies?
This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 12, 2021 Category: Food Science Authors: Gerhard Rogler, Michael Scharl, Marianne Spalinger, Bahtiyar Yilmaz, Michael Zaugg, Martin Hersberger, Philipp Schreiner, Luc Biedermann, Hans Herfarth Tags: Review Source Type: research

Back Cover: β‐1,3/1,6‐Glucans and Immunity: State of the Art and Future Directions
Mol. Nutr. Food Res. 2020,65,1901071DOI:10.1002/mnfr.201901071Dietary stressors, including saturated fats and sugars, generate endogenous stress signals that reconfigure host metabolism towards a glycolytic pro ‐inflammatory state. Conversely, exercise, unsaturated fats, and dietary antioxidants direct metabolism towards oxidative phosphorylation and lower reactive oxygen species. This metabolic environment promotes resolution of inflammation. Cellular receptors like TLR4 and the NLRP3 inflammasome sense metabolic stressors and re‐program macrophages. This is reported by Elena De Marco Castro, Philip C. Calder, and Hel...
Source: Molecular Nutrition and Food Research - January 9, 2021 Category: Food Science Authors: Elena De Marco Castro, Philip C. Calder, Helen M. Roche Tags: Back Cover Source Type: research

Front Cover: Dietary Fiber from Oat and Rye Brans Ameliorate Western Diet –Induced Body Weight Gain and Hepatic Inflammation by the Modulation of Short‐Chain Fatty Acids, Bile Acids, and Tryptophan Metabolism
Mol. Nutr. Food Res. 2021,65,1900580DOI:10.1002/mnfr.201900580Addition of oat or rye fiber to a western diet changes gut microbiota and its metabolites which hold signalling capacity to reduce body weight gain through improved gut integrity and alleviated liver inflammation. The authors observed these changes to be associated with increased SCFA synthesis, diversion of tryptophan metabolism from serotonin to indole production and altered BA metabolism. This is reported by Zuzanna Maria Kundi, Jetty Chung ‐Yung Lee, Jussi Pihlajamäki, Chi Bun Chan, Kin Sum Leung, Stephanie Sik Yu So, Emilia Nordlund, Marjukka Kolehma...
Source: Molecular Nutrition and Food Research - January 9, 2021 Category: Food Science Authors: Zuzanna Maria Kundi, Jetty Chung ‐Yung Lee, Jussi Pihlajamäki, Chi Bun Chan, Kin Sum Leung, Stephanie Sik Yu So, Emilia Nordlund, Marjukka Kolehmainen, Hani El‐Nezami Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 1'21
Molecular Nutrition& Food Research, Volume 65, Issue 1, January 2021. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 9, 2021 Category: Food Science Tags: Editorial Board Source Type: research

Metabolism and Inflammation: New Synergies and Insights
Molecular Nutrition& Food Research, Volume 65, Issue 1, January 2021. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - January 9, 2021 Category: Food Science Authors: Helen M. Roche Tags: Guest ‐Editorial Source Type: research

Black Tea Theaflavin Detoxifies Metabolic Toxins in the Intestinal Tract of Mice
ConclusionTF has the capacity to remove the endogenous metabolic toxins through oxidation, amination, and MGO conjugation in the intestinal tract, which could potentially explain why TF still generates in vivo efficacy while showing a poor systematic bioavailability.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 31, 2020 Category: Food Science Authors: Shuwei Zhang, Christina Ohland, Christian Jobin, Shengmin Sang Tags: Research Article Source Type: research

Lactucopicrin Inhibits Cytoplasmic Dynein ‐Mediated NF‐κB Activation in Inflammated Macrophages and Alleviates Atherogenesis in Apolipoprotein E‐Deficient Mice
ConclusionDietary lactucopicrin inhibits atherogenesis in mice likely by its anti ‐inflammatory property. These findings suggest that dietary supplementation with lactucopicrin is a promising strategy to inhibit atherosclerotic cardiovascular disease.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 30, 2020 Category: Food Science Authors: Luanying He, Hui Weng, Qing Li, Guojun Shi, Xiuping Liu, Yushi Du, Jiakun Zheng, Wenhua Ling, Dongliang Wang Tags: Research Article Source Type: research

Delivery of Acetate to the Peripheral Blood after Consumption of Foods High in Short ‐Chain Fatty Acids
ConclusionFermented foods and beverages are a natural source of dietary SCFA that acutely deliver SCFA to the blood. If systemic delivery is needed for immunological and metabolic effects to occur, these may be achieved if delivered over a longer period of time.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 29, 2020 Category: Food Science Authors: Paul A. Gill, Alexander Bogatyrev, Menno C. Zelm, Peter R. Gibson, Jane G. Muir Tags: Research Article Source Type: research

Carbohydrate Intake and Hyperlipidemia among Population with High ‐Carbohydrate Diets: The Health Examinees Gem Study
The association between carbohydrate (CHO) intake from low ‐, medium‐, and high‐glycemic index foods and hyperlipidemia among population with a high‐CHO diet is examined. Increasing CHO intake as a replacement for fat is associated with increasing prevalence of high triglyceride and low HDL‐cholesterol and inversely associated with the prevalence of high LDL‐ and total‐cholesterol. ScopeThe association between carbohydrate intake from low ‐, medium‐, and high‐glycemic index (GI) foods and hyperlipidemia among population with a high‐carbohydrate diet is examined.Methods and resultsA total of 93,870 par...
Source: Molecular Nutrition and Food Research - December 28, 2020 Category: Food Science Authors: Woo ‐Kyoung Shin, Sangah Shin, Jong‐koo Lee, Daehee Kang, Jung Eun Lee Tags: Research Article Source Type: research

Hydroxytyrosol Acetate Improves the Cognitive Function of  APP/PS1 Transgenic Mice in ERβ‐dependent Manner
ConclusionsThis study suggests that as the bioactive component of olive oil, HT ‐ac is a promising neuroprotective nutrient that may be used to alleviate AD‐related cognitive dysfunction. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 28, 2020 Category: Food Science Authors: Chuan Qin, Shaoqin Hu, Shuangxi Zhang, Daina Zhao, Yongyao Wang, Hua Li, Yunhua Peng, Le Shi, Xiaohong Xu, Changhe Wang, Jiankang Liu, Ying Cheng, Jiangang Long Tags: Research Article Source Type: research

Flexibility of Gut Microbiota in Ageing Individuals during Dietary Fiber Long ‐chain Inulin Intake
ConclusionsOverall, we show for the first time that the gut microbiota composition is still sensitive to chicory long ‐chain inulin induced changes in an ageing population, although this did not translate into an improved immune response to a HB vaccine.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 28, 2020 Category: Food Science Authors: M. B. G. Kiewiet, M. E. Elderman, S. El Aidy, J.G.M. Burgerhof, H. Visser, E. E. Vaughan, M. M. Faas, P. Vos Tags: Research Article Source Type: research

Punicalagin Prevents Hepatic Steatosis Through Improving Lipid Homeostasis and Inflammation in Liver and Adipose Tissue and Modulating Gut Microbiota in Western diet ‐fed Mice
Conclusions: Our findings suggest that punicalagin improves hepatic steatosis induced by WD, in part through regulating lipid homeostasis and inflammation in liver and adipose tissue and restoring microbiota shift and impaired gut barrier function. Thus, punicalagin could be potentially developed as a potential prevention strategy in combating nonalcoholic fatty liver disease.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 24, 2020 Category: Food Science Authors: Huanhuan Liu, Qiuyao Zhan, Xin Miao, Xiaodong Xia, Gaoji Yang, Xiaoli Peng, Chunhong Yan Tags: Research Article Source Type: research

Back Cover: The Beneficial Effects of Apical Sodium ‐Dependent Bile Acid Transporter Inactivation Depend on Dietary Fat Composition
Mol. Nutr. Food Res. 2020,64,2000750DOI:10.1002/mnfr.202000750Inactivation of the apical sodium bile acid transporter (ASBT) interrupts the enterohepatic circulation of bile acids and subsequently impairs lipid absorption.Asbt−/− mice are protected from obesity, insulin resistance and fatty liver disease when fed a high ‐fat diet rich in saturated but not polyunsaturated fatty acids, highlighting the importance of dietary composition in assessment of treatments targeting bile acid homeostasis. This is reported by Ivo P. van de Peppel, Anuradha Rao, Marleen B. Dommerholt, Laura Bongiovanni, Rachel Thomas, Alai...
Source: Molecular Nutrition and Food Research - December 17, 2020 Category: Food Science Authors: Ivo P. Peppel, Anuradha Rao, Marleen B. Dommerholt, Laura Bongiovanni, Rachel Thomas, Alain Bruin, Saul J. Karpen, Paul A. Dawson, Henkjan J. Verkade, Johan W. Jonker Tags: Back Cover Source Type: research

Front Cover: Salted and Unsalted Zh àcài (Brassica juncea var. tumida) Alleviated High‐Fat Diet‐Induced Dyslipidemia by Regulating Gut Microbiota: A Multiomics Study
Mol. Nutr. Food Res. 2020,64,2000798DOI:10.1002/mnfr.202000798Zh àcài, a salting‐processedBrassica juncea var.tumida vegetable, is widely consumed as a pickle. The results of multiomics study suggest that consumption of salted and unsalted Zh àcài may effectively prevent high‐fat‐induced dyslipidemia by regulating gut microbiota. Moverover, the anti‐dyslipidemia effect of unsalted Zhàcài is stronger than that of salted Zhàcài. This is reported by Wenfeng Li, Chunlian Chen, Mengting Chen, Xiangyang Zhang, Qin Ji, Yu Wang, Qiao ran Zheng, Si Tan, Xiaoxv Gao, Yal...
Source: Molecular Nutrition and Food Research - December 17, 2020 Category: Food Science Authors: Wenfeng Li, Chunlian Chen, Mengting Chen, Xiangyang Zhang, Qin Ji, Yu Wang, Qiaoran Zheng, Si Tan, Xiaoxv Gao, Yalong Lu Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 24'20
Molecular Nutrition& Food Research, Volume 64, Issue 24, December 2020. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 17, 2020 Category: Food Science Tags: Editorial Board Source Type: research

Discriminating dietary responses by combining transcriptomics and metabolomics data in nutrition intervention studies
ConclusionThe integration of associated “omics” datasets can help to clarify the subtle signals observed in nutritional interventions. The performance of each integration tool is differently influenced by study design, size of the datasets, and sample size.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 16, 2020 Category: Food Science Authors: Kathryn J Burton ‐Pimentel, Grégory Pimentel, Maria Hughes, Charlotte CJR Michielsen, Attia Fatima, Nathalie Vionnet, Lydia A Afman, Helen M Roche, Lorraine Brennan, Mark Ibberson, Guy Vergères Tags: Research Article Source Type: research

Vitamin D rescues pancreatic β cell dysfunction due to iron overload via elevation of the vitamin D receptor and maintenance of Ca2+ homeostasis
ConclusionsWe showed that functional failure of β cells due to iron accumulation was rescued by 1,25(OH)2D3, and iron overload significantly reduced VDR levels in β cells. These results suggest that iron and vitamin D inversely influence pancreatic β cell function.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 15, 2020 Category: Food Science Authors: Yoo Jeong Lee, Gyu Hee Kim, Jin ‐soo Yoo, Sang Ick Park, Joo Hyun Lim Tags: Research Article Source Type: research

The Beneficial Effects of Red Sun ‐Dried Capsicum annuum L. cv Senise Extract with Antioxidant Properties in Experimental Obesity are Associated with Modulation of the Intestinal Microbiota
ConclusionsThe extract could be considered a new potential approach for the treatment of obesity, complementary to dietary restrictions.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 10, 2020 Category: Food Science Authors: Chiara Sinisgalli, Teresa Vezza, Patricia Diez ‐Echave, Angela Ostuni, Immacolata Faraone, Laura Hidalgo‐Garcia, Daniela Russo, Maria Francesca Armentano, José Garrido‐Mesa, Maria Elena Rodriguez‐Cabezas, Alba Rodríguez Nogales, Luigi Tags: Research Article Source Type: research

Hydroxytyrosol Acetate Improves the Cognitive Function of APP/PS1 Transgenic Mice in ER β‐dependent Manner
ConclusionsOur study suggests that as the bioactive component of olive oil, HT ‐ac is a promising neuroprotective nutrient that may be used to alleviate AD‐related cognitive dysfunction.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 9, 2020 Category: Food Science Authors: Chuan Qin, Shaoqin Hu, Shuangxi Zhang, Daina Zhao, Yongyao Wang, Hua Li, Yunhua Peng, Le Shi, Xiaohong Xu, Changhe Wang, Jiankang Liu, Ying Cheng, Jiangang Long Tags: Research Article Source Type: research

Urine Metabolites Associated with the Dietary Approaches to Stop Hypertension (DASH) Diet: Results from the DASH ‐Sodium Trial
ConclusionsCandidate biomarkers of the DASH diet identified in serum replicated in urine. Replicated influential metabolites are likely to be objective biomarkers of the DASH diet.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 9, 2020 Category: Food Science Authors: Hyunju Kim, Alice H. Lichtenstein, Kari E. Wong, Lawrence J. Appel, Josef Coresh, Casey M. Rebholz Tags: Research Article Source Type: research

Metabolomic Changes after Coffee Consumption: New Paths on the Block
ConclusionThis information has provided new insights into the metabolic routes by which coffee and coffee ‐related metabolites may exert effects on human health.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 9, 2020 Category: Food Science Authors: Claudia Favari, Laura Righetti, Michele Tassotti, Lee A. Gethings, Daniela Martini, Alice Rosi, Monica Antonini, Josep Rubert, Claudine Manach, Alessandra Dei Cas, Riccardo Bonadonna, Furio Brighenti, Chiara Dall'Asta, Pedro Mena, Daniele De Tags: Research Article Source Type: research

Vitamin A and D Absorption in Adults with Metabolic Syndrome versus Healthy Controls: A Pilot Study Utilizing Targeted and Untargeted LC –MS Lipidomics
Absorption of vitamins A, D, and lipids are investigated in metabolic syndrome (MetS) versus healthy subjects. Vitamin A absorption increases in MetS (trend) and correlates with a subset of phosphocholines. Vitamin D absorption is not different between groups. This warrants investigation of shared vitamin A/phosphocholine enzymes and distinct vitamin A versus D absorption pathways to improve their status in MetS. ScopePersons with metabolic syndrome (MetS) absorb less vitamin E than healthy controls. It is hypothesized that absorption of fat ‐soluble vitamins (FSV) A and D2 would also decrease with MetS status and that t...
Source: Molecular Nutrition and Food Research - December 7, 2020 Category: Food Science Authors: Haley Chatelaine, Priyankar Dey, Xiaokui Mo, Eunice Mah, Richard S. Bruno, Rachel E. Kopec Tags: Research Article Source Type: research

Milk Fat Globule Membrane as A Modulator Of Infant Metabolism and Gut Microbiota: A Formula Supplement Narrowing the Metabolic Differences Between Breast ‐Fed and Formula‐Fed Infants
Conclusion: Supplementing MFGM in a formula reduced some metabolic gaps between formula ‐fed and breastfed infants.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 7, 2020 Category: Food Science Authors: Hanna Lee, Carolyn M. Slupsky, Anne Heckmann, Britt Christensen, Yongmei Peng, Xiaonan Li, Olle Hernell, Bo L önnerdal, Zailing Li Tags: Research Article Source Type: research

Carbohydrate Intake and Hyperlipidaemia Among Population With High ‐Carbohydrate Diets: The Health Examinees Gem Study
ConclusionsIncreasing low ‐quality carbohydrate intake was associated with increasing prevalence of high TGs and low HDL‐cholesterol, especially among individuals who were not obese.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 7, 2020 Category: Food Science Authors: Woo ‐Kyoung Shin, Sangah Shin, Jong‐koo Lee, Daehee Kang, Jung Eun Lee Tags: Research Article Source Type: research

Role of Dietary Micronutrients on Gut Microbial Dysbiosis and Modulation in Inflammatory Bowel Disease
This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 7, 2020 Category: Food Science Authors: Palni Kundra, Carole Rachm ühl, Christophe Lacroix, Annelies Geirnaert Tags: Review Source Type: research

Interindividual Differences in Human in vitro Intestinal Microbial Conversion of Green Tea ( ‐)‐Epigallocatechin‐3‐O‐gallate and Consequences for Activation of Nrf2 Mediated Gene Expression
Conclusions: Given these results and taking the level of formation into account, it is concluded that especially gallic acid and pyrogallol contribute to the EpRE ‐mediated beneficial effects of EGCG. The interindividual differences in their formation may result in interindividual differences in the beneficial effects of EGCG and green tea consumption.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 7, 2020 Category: Food Science Authors: Chen Liu, Jacques Vervoort, Joris den Elzen, Karsten Beekmann, Marta Baccaro, Laura Haan, Ivonne M.C.M. Rietjens Tags: Research Article Source Type: research

Pterostilbene alleviates A β1‐42‐induced cognitive dysfunction via inhibition of oxidative stress by activating Nrf2 signaling pathway
ConclusionThe present study reported that pterostilbene alleviated A β1 ‐42‐induced cognitive dysfunction in mice. The mechanism of pterostilbene can be associated to the inhibition of oxidative stress through the Nrf2 signaling pathway.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 6, 2020 Category: Food Science Authors: Jikai Xu, Jingyu Liu, Qing Li, Yan Mi, Di Zhou, Qingqi Meng, Gang Chen, Ning Li, Yue Hou Tags: Research Article Source Type: research

No Effect of Dietary Fish oil Supplementation on the Recruitment of Brown and Brite Adipocytes in Mice or Humans Under Thermoneutral Conditions
ConclusionThus, our data question the hypothesized potential of n3 ‐polyunsaturated fatty acids as modulators of adipocyte‐based thermogenesis and energy balance regulation.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 4, 2020 Category: Food Science Authors: Stefanie F. Maurer, Sebastian Dieckmann, Jens Lund, Tobias Fromme, Anne Lundby Hess, C écilia Colson6, Louise Kjølbæk, Arne Astrup, Matthew Paul Gillum, Lesli Hingstrup Larsen, Gerhard Liebisch, Ez‐Zoubir Amri, Martin Klingenspor Tags: Research Article Source Type: research

The garlic compound Z ‐ajoene, S‐thiolates COX2 and STAT3 and dampens the inflammatory response in RAW264.7 macrophages
ConclusionThe characterisation ofZ‐ajoene's activity of targeting and covalently modifying STAT3 and COX2, both important regulators of inflammation, may contribute to the health benefits of regular dietary garlic consumption.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 4, 2020 Category: Food Science Authors: Jessica K. Hitchcock, Nonkululeko Mkwanazi, Christopher Barnett, Lisa M. Graham, Arieh A. Katz, Roger Hunter, Georgia Sch äfer, Catherine H. Kaschula Tags: Research Article Source Type: research

Low Maternal Dietary Intake of Choline Regulates Toll ‐Like Receptor 4 Expression Via Histone H3K27me3 in Foetal Mouse Neural Progenitor Cells
ConclusionThese data reveal an epigenetic mechanism for the effect of maternal choline availability on brain development, suggesting a likely intervention for neurodevelopmental diseases.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 3, 2020 Category: Food Science Authors: Xingying Guan, Xuedan Chen, Limeng Dai, Jiming Ma, Qiming Zhang, Song Qu, Yun Bai, Yanyan Wang Tags: Research Article Source Type: research

Front Cover: Improved Glucose Intolerance through a Distinct Mouse Olfactory Receptor 23 ‐Induced Signaling Pathway Mediating Glucose Uptake in Myotubes and Adipocytes
This study evaluates the role of mouse olfactory receptor 23 (MOR23) in the regulation of glucose uptake in myotubes and adipocytes. MOR23 stimulation by the agonist (cedrene) results in increased glucose uptake, which is absent in MOR23 ‐depleted myotubes and adipocytes. These data show that MOR23 is a novel factor for the regulation of glucose uptake and has therapeutic potential for diabetes treatment. This is reported by Wesuk Kang, Kelun Zhang, Tao Tong, and Taesun Park in article1901329. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 2, 2020 Category: Food Science Authors: Wesuk Kang, Kelun Zhang, Tao Tong, Taesun Park Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 23'20
(Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - December 2, 2020 Category: Food Science Tags: Editorial Board Source Type: research

Yellow Tea Stimulates Thermogenesis in Mice Through Heterogeneous Browning of Adipose Tissues
ConclusionDietary YT induces adaptive thermogenesis through increasing mitochondrial biogenesis in EAT, inducing beigeing in SAT and enhancing browning in the BAT.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - November 30, 2020 Category: Food Science Authors: Na Xu, Jun Chu, Rongrong Dong, Fengjuan Lu, Xinfeng Zhang, Min Wang, Ying Shen, Zhongwen Xie, Chi ‐Tang Ho, Chung S. Yang, Yijun Wang, Xiaochun Wan Tags: Research Article Source Type: research

Active Vitamin D3 Treatment Attenuated Bacterial Translocation Via Improving Intestinal Barriers in Cirrhotic Rats
ConclusionCalcitriol treatment attenuated intestinal permeability, reduced bacterial translocation and enriched potentially beneficial gut microbiota in cirrhotic rats that may enable it as a potential therapeutic agent to prevent cirrhotic complications.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - November 30, 2020 Category: Food Science Authors: Pei ‐Chang Lee, Yun‐Chen Hsieh, The‐Ia Huo, Ueng‐Cheng Yang, Chao‐Hsiung Lin, Chung‐Pin Li, Yi‐Hsiang Huang, Ming‐Chih Hou, Han‐Chieh Lin, Kuei‐Chuan Lee Tags: Research Article Source Type: research

Sweetness Perception is not Involved in the Regulation of Blood Glucose after Oral Application of Sucrose and Glucose Solutions in Healthy Male Subjects
ConclusionThe results indicate that the structure of the carbohydrate has a stronger impact on the regulation of blood glucose levels than the perceived sweetness.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - November 29, 2020 Category: Food Science Authors: Verena Gr üneis, Kerstin Schweiger, Claudia Galassi, Corinna M. Karl, Julia Treml, Jakob P. Ley, Jürgen König, Gerhard E. Krammer, Veronika Somoza, Barbara Lieder Tags: Research Article Source Type: research

Catechin ‐Rich Green Tea Extract and the Loss‐of‐TLR4 Signaling Differentially Alter the Hepatic Metabolome in Mice with Nonalcoholic Steatohepatitis
ConclusionGTE limitedly alters the hepatic metabolome consistent with a TLR4 ‐dependent mechanism. This suggests that the anti‐inflammatory activities of GTE and loss‐of‐TLR4 signaling that regulate hepatic metabolism to abrogate NASH are likely due to distinct mechanisms.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - November 28, 2020 Category: Food Science Authors: Geoffrey Y. Sasaki, Jinhui Li, Morgan J. Cichon, Rachel E. Kopec, Richard S. Bruno Tags: Research Article Source Type: research

Suppression of Hippo Pathway by Food Allergen Exacerbates Intestinal Epithelia Instability and Facilitates Hypersensitivity
ConclusionsBoth in vivo and in vitro data demonstrated that the two food allergens suppressed Hippo pathway by downregulating TAZ expression, resulting in intestinal epithelia instability, and finally leading to hypersensitivity reactions. These findings provided potential therapeutic targets and molecular markers for food allergy, and provide dietary guidelines for allergenic individuals.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - November 27, 2020 Category: Food Science Authors: Chong Wang, Wanglei lin, Yanbo Wang, Linglin Fu Tags: Research Article Source Type: research

One Carbon Metabolism and Mammalian Pregnancy Outcomes
This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - November 23, 2020 Category: Food Science Authors: Shuang Cai, Shuang Quan, Guangxin Yang, Qianhong Ye, Meixia Chen, Haitao Yu, Gang Wang, Yuming Wang, Xiangfang Zeng, Shiyan Qiao Tags: Review Source Type: research

Editorial Board: Mol. Nutr. Food Res. 22'20
Molecular Nutrition& Food Research, Volume 64, Issue 22, November 2020. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - November 23, 2020 Category: Food Science Tags: Editorial Board Source Type: research