Syringaresinol Protects against Type 1 Diabetic Cardiomyopathy by Alleviating Inflammation Responses, Cardiac Fibrosis and Oxidative Stress
ConclusionThe results indicated that SYR could be a potential therapeutic agent for the treatment of diabetic cardiomyopathy by inhibiting inflammation, fibrosis and oxidative stress. The signaling pathway of Keap1/Nrf2 and TGF ‐β/Smad could be used as therapeutic targets for diabetic complications.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 30, 2020 Category: Food Science Authors: Guangru Li, Lei Yang, Lifeng Feng, Jiu Yang, Yafei Li, Jiale An, Dihua Li, Yang Xu, Yang Gao, Jing Li, Jie Liu, Liang Yang, Zhi Qi Tags: Research Article Source Type: research

Antibiotic Treatment Reduces the Health Benefits of Soy Protein
ConclusionIn conclusion, the evidence suggests that the health benefits of soy protein are partly dependent of the gut microbiota.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 30, 2020 Category: Food Science Authors: Monica S ánchez‐Tapia, Daniela Moreno‐Vicencio, Guillermo Ordáz‐Nava, Martha Guevara‐Cruz, Omar Granados‐Portillo, Ariana Vargas‐Castillo, Nimbe Torres, Armando R. Tovar Tags: Research Article Source Type: research

Choice of Lipid Emulsion Determines Inflammation of the Gut ‐Liver Axis, Incretin Profile, and Insulin Signaling in a Murine Model of Total Parenteral Nutrition
ConclusionsOV ‐TPN as opposed to IL‐TPN mitigates inflammation in the liver and reduces the negative metabolic effects of hyperinsulinemia and hyperglucagonemia by “re‐sensitizing” the liver and skeletal muscle to insulin.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 30, 2020 Category: Food Science Authors: Phing ‐How Lou, Eliana Lucchinetti, Paulina Wawrzyniak, Yasser Morsy, Marcin Wawrzyniak, Michael Scharl, Stefanie D. Krämer, Gerhard Rogler, Martin Hersberger, Michael Zaugg Tags: Research Article Source Type: research

Methionine Restriction Regulates Cognitive Function in High ‐fat Diet‐fed Mice: Roles of Diurnal Rhythms of SCFAs Producing‐ and Inflammation‐ related Microbes
ConclusionMR could serve as a potential nutritional intervention for attenuating obesity ‐induced cognitive impairments by balancing the circadian rhythm in microbiome‐gut‐brain homeostasis.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 30, 2020 Category: Food Science Authors: Luanfeng Wang, Bo Ren, Yan Hui, Chuanqi Chu, Zhenting Zhao, Yuyu Zhang, Beita Zhao, Renjie Shi, Junli Ren, Xiaoshuang Dai, Zhigang Liu, Xuebo Liu Tags: Research Article Source Type: research

Propagule Powder of Japanese Yam (Dioscorea Japonica) Reduces High ‐Fat Diet‐Induced Metabolic Stress in Mice Through the Regulation of Hepatic Gene Expression
ConclusionPropagules act to delay the occurrence of hepatic disease by suppressing carbohydrate and fat metabolism disorders in high ‐fat loaded mice.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 30, 2020 Category: Food Science Authors: Fumika Shinozaki, Asuka Kamei, Yuki Watanabe, Akihito Yasuoka, Kousuke Shimada, Kaori Kondo, Soichi Arai, Takashi Kondo, Keiko Abe Tags: Research Article Source Type: research

Long ‐Term Intake of Pork Meat Proteins Altered the Composition of Gut Microbiota and Host‐Derived Proteins in the Gut Contents Of Mice
ConclusionsPork meat protein diets altered the gut microbiota composition and specific gut microbes may have a great impact on protein digestion and absorption by regulating the secretion of digestive proteins from the host. These findings provide a new insight into the associations of long ‐term intake of meat protein diet with gut microbiota and host.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 30, 2020 Category: Food Science Authors: Yunting Xie, Chao Wang, Di Zhao, Changyu Zhou, Chunbao Li Tags: Research Article Source Type: research

Poplar Propolis Ethanolic Extract Reduces Body Weight Gain and Glucose Metabolism Disruption in High ‐fat Diet‐fed Mice
ConclusionPPEE supplementation may represent an interesting preventive strategy to tackle the onset of obesity and associated metabolic disorders.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 30, 2020 Category: Food Science Authors: Nicolas Cardinault, Franck Tourniaire, Julien Astier, Charl ène Couturier, Estelle Perrin, Julie Dalifard, Eva Seipelt, Lourdes Mounien, Claire Letullier, Lauriane Bonnet, Esma Karkeni, Naïma Delbah, Stéphane Georgé, Jean‐François Land Tags: Research Article Source Type: research

Inflammatory Diseases and Vitamin E —What Do We Know and Where Do We Go?
Inflammatory diseases are a significant global burden, with the multiprotein complex NLRP3 being conducted as a key player. Vitamin E is considered the most effective nutritional antioxidant, with additional anti ‐inflammatory properties. Thus, vitamin E is a promising dietary therapeutic agent. This review gives an overview on the interactions of vitamin E and inflammatory diseases and involved cellular pathways. AbstractInflammation ‐driven diseases and related comorbidities, such as the metabolic syndrome, obesity, fatty liver disease, and cardiovascular diseases cause significant global burden. There is a growing b...
Source: Molecular Nutrition and Food Research - July 29, 2020 Category: Food Science Authors: Maria Wallert, Lisa B örmel, Stefan Lorkowski Tags: Review Source Type: research

Food Processing does not Abolish the Allergenicity of the Carrot Allergen Dau c 1: Influence of pH, Temperature and the Food Matrix
ConclusionsPatients allergic to carrots should avoid processed carrot containing foodstuff because heating or pH treatment do not completely abolish the allergenicity of Dau  c 1.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 25, 2020 Category: Food Science Authors: Thessa Jacob, Lothar Vogel, Andreas Reuter, Andrea Wangorsch, Carolin Kring, Vera Mahler, Birgitta M. W öhrl Tags: Research Article Source Type: research

Front Cover: Prenatal High ‐Salt Diet–Induced Metabolic Disorders via Decreasing Peroxisome Proliferator–Activated Receptor Gamma Coactivator 1α in Adult Male Rat Offspring
Mol. Nutr. Food Res. 2020,64,https://doi.org/10.1002/mnfr.2020001962000196DOI:10.1002/mnfr.202000196Maternal high ‐salt diet during gestation markedly down‐regulated the expression of PGC‐1α in skeletal muscle of adult offspring, which led to impaired mitochondrial function and reduced Glut4 levels, which ultimately contributed to metabolic disorders. These findings enhance the understanding of metabolic dysfunction development of fetal origins. This is reported by Yanping Liu, Chunli Yang, Xueqin Feng, Linglu Qi, Jun Guo, Dan Zhu, Phung N. Thai, Yingying Zhang, Pengjie Zhang, Miao Sun, Juanxiu Lv, Lubo Zhang, ...
Source: Molecular Nutrition and Food Research - July 21, 2020 Category: Food Science Authors: Yanping Liu, Chunli Yang, Xueqin Feng, Linglu Qi, Jun Guo, Dan Zhu, Phung N. Thai, Yingying Zhang, Pengjie Zhang, Miao Sun, Juanxiu Lv, Lubo Zhang, Zhice Xu, Xiyuan Lu Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 14'20
Molecular Nutrition& Food Research, Volume 64, Issue 14, July 2020. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 21, 2020 Category: Food Science Tags: Editorial Board Source Type: research

Inflammatory Diseases and Vitamin E – What Do We Know and Where Do We Go?
This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 21, 2020 Category: Food Science Authors: Maria Wallert, Lisa B örmel, Stefan Lorkowski Tags: Review Source Type: research

miRNA/Target Gene Profile of Endothelial Cells Treated with Human Triglyceride ‐Rich Lipoproteins Obtained after a High‐Fat Meal with Extra‐Virgin Olive Oil or Sunflower Oil
ConclusionsEVOO ‐derived TRLs seem to produce a more atheroprotective profile than SO‐derived TRLs. This study provides alternative mechanisms on the protective role of EVOO against the atherogenic process through miRNA regulation in endothelial cells.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 14, 2020 Category: Food Science Authors: Concepci ón Santiago‐Fernandez, Flores Martin‐Reyes, Rocío Bautista, Mónica Tome, Josefa Gómez‐Maldonado, Carolina Gutierrez‐Repiso, Francisco J. Tinahones, Eduardo Garcia‐Fuentes, Lourdes Garrido‐Sánchez Tags: Research Article Source Type: research

Microbiome Transfer Partly Overrides Lack of IL ‐1RI Signaling to Alter Hepatic but not Adipose Tissue Phenotype and Lipid Handling following a High‐Fat Diet Challenge
ConclusionTransfer of SCFA ‐producing microbiota from IL‐1RI−/− mice highlights a new connection between diet, inflammatory signaling, and the gut microbiome, an association that is dependent on the nature of the dietary fat challenge. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 12, 2020 Category: Food Science Authors: Jessica C. Ralston, Kathleen A. J. Mitchelson, Gina M. Lynch, Tam T. T. Tran, Hao Wang, Conall R. Strain, Yvonne M. Lenighan, Elaine B. Kennedy, Catherine Stanton, Fiona C. McGillicuddy, Qiaozhu Su, Paul W. O'Toole, Helen M. Roche Tags: Research Article Source Type: research

Stearidonic ‐Enriched Soybean Oil Modulates Obesity, Glucose Metabolism, and Fatty Acid Profiles Independently of Akkermansia Muciniphila
ConclusionTogether, these findings support the utilization of SDA ‐enriched diets to modulate weight gain, glucose metabolism, and fatty acid profiles of liver and adipose tissue.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 12, 2020 Category: Food Science Authors: Rafael R. Segura Munoz, Truyen Quach, Jo ão C. Gomes‐Neto, Yibo Xian, Pamela A. Pena, Steven Weier, Michael A. Pellizzon, Hatem Kittana, Liz A. Cody, Abby L. Geis, Kari Heck, Robert J. Schmaltz, Laure B. Bindels, Edgar B. Cahoon, Andrew K Tags: Research Article Source Type: research

Caffeine Upregulates Hepatic Sex Hormone ‐Binding Globulin Production by Increasing Adiponectin Through AKT/FOXO1 Pathway in White Adipose Tissue
ConclusionsOur results showed that caffeine upregulates hepatic SHBG expression by increasing adiponectin production through AKT/FOXO1 pathway in the adipose tissue.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 11, 2020 Category: Food Science Authors: Laura Brians ó‐Llort, Lidia Fuertes‐Rioja, Lorena Ramos‐Perez, Cristina Hernandez, Rafael Simó, David M. Selva Tags: Research Article Source Type: research

A Hybrid In Silico/In Vitro Target Fishing Study to Mine Novel Targets of Urolithin A and B: A Step Towards a Better Comprehension of their Estrogenicity
ConclusionsThe work described target fishing as an effective tool to identify unexpected targets of food bioactives detailing the interaction at a molecular level. Specifically, it described, for the first time, 17 β‐hydroxysteroid dehydrogenase as a target of urolithins and highlighted the need of further investigations to widen the understanding of urolithins as estrogen modulators in living organisms.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 8, 2020 Category: Food Science Authors: Luca Dellafiora, Marco Milioli, Angela Falco, Margherita Interlandi, Abdelrahman Mohamed, Martin Frotscher, Benedetta Riccardi, Paola Puccini, Daniele Del Rio, Gianni Galaverna, Chiara Dall'Asta Tags: Research Article Source Type: research

Targeting the Liver ‐Brain Axis with Hop‐Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice
ConclusionThese observations suggest that XN, DXN, and TXN may alleviate obesity ‐induced metabolic and neurocognitive impairments by targeting the liver‐brain axis. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 6, 2020 Category: Food Science Authors: Ines L. Paraiso, Johana S. Revel, Jaewoo Choi, Cristobal L. Miranda, Parnian Lak, Chrissa Kioussi, Gerd Bobe, Adrian F. Gombart, Jacob Raber, Claudia S. Maier, Jan F. Stevens Tags: Research Article Source Type: research

Front Cover: Anthocyanin ‐Biofortified Colored Wheat Prevents High Fat Diet–Induced Alterations in Mice: Nutrigenomics Studies
Mol. Nutr. Food Res. 2020,64,https://doi.org/10.1002/mnfr.2019009991900999DOI:10.1002/mnfr.201900999In articlehttps://doi.org/10.1002/mnfr.2019009991900999, Kanthi Kiran Kondepudi, Mahendra Bishnoi, Monika Garg, and co ‐workers find that anthocyanin‐biofortified black wheat consumption reduces body weight gain and fat pad size in high‐fat‐diet‐induced obesity mouse models. This occurs by an increase in adipocyte differentiation and fatty acid β‐oxidation and removal of β‐oxidation‐generated free radicals by antioxidant anthocyanins, leading to no ectopic fat deposition in organs like the liver and...
Source: Molecular Nutrition and Food Research - July 3, 2020 Category: Food Science Authors: Saloni Sharma, Pragyanshu Khare, Ashish Kumar, Venkatesh Chunduri, Aman Kumar, Payal Kapoor, Priyanka Mangal, Kanthi Kiran Kondepudi, Mahendra Bishnoi, Monika Garg Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 13'20
Molecular Nutrition& Food Research, Volume 64, Issue 13, July 2020. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 3, 2020 Category: Food Science Tags: Editorial Board Source Type: research

Grape Powder Supplementation Attenuates Prostate Neoplasia Associated with Pten Haploinsufficiency in Mice Fed High ‐Fat Diet
Conclusions: GP diet supplementation could be a beneficial chemopreventive strategy for obesity ‐related inflammation and prostate cancer progression. Monitoring serum miRNAs could facilitate the non‐invasive evaluation of chemoprevention efficacy.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 2, 2020 Category: Food Science Authors: Tanvi Joshi, Ishani Patel, Avinash Kumar, Virginia Donovan, Anait S. Levenson Tags: Research Article Source Type: research

Effects of a Cumulative, Suboptimal Supply of Multiple Trace Elements in Mice: Trace Element Status, Genomic Stability, Inflammation, and Epigenetics
Conclusions: Despite homeostatic regulation of most TEs in response to a low intake, this condition still has substantial effects on health parameters. It appears that the liver and immune system react particularly sensitive towards changes in TE intake. The reduced Fe status might be the primary driver for the observed effects.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 1, 2020 Category: Food Science Authors: Hannah Finke, Nicola Winkelbeiner, Kristina Lossow, Barbara Hertel, Viktoria K. Wandt, Maria Schwarz, Gabriele Pohl, Johannes F. Kopp, Franziska Ebert, Anna P. Kipp, Tanja Schwerdtle Tags: Research Article Source Type: research

Prebiotic Oligofructose Prevents Antibiotic ‐Induced Obesity Risk and Improves Metabolic and Gut Microbiota Profiles in Rat Dams and Offspring
Conclusions: Antibiotic use during pregnancy/lactation increases adiposity and impairs post ‐partum weight loss in dams. Co‐administering prebiotics with antibiotics in rat dams prevented obesity risk in offspring and was associated with altered gut microbiota.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 1, 2020 Category: Food Science Authors: Teja Klancic, Isabelle Laforest ‐Lapointe, Ashley Choo, Jodi E. Nettleton, Faye Chleilat, Erin W. Noye Tuplin, Erna Alukic, Nicole A. Cho, Alissa C. Nicolucci, Marie‐Claire Arrieta, Raylene A. Reimer Tags: Research Article Source Type: research

Long Term Exposure to a Grape Seed Proanthocyanidin Extract Enhances L ‐Cell Differentiation in Intestinal Organoids
ConclusionsThis study shows the potential role of GSPE in promoting enteroendocrine differentiation, effect that is not mediated by EC or GA.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 1, 2020 Category: Food Science Authors: Àngela Casanova‐Martí, Noemi González‐Abuín, Joan Serrano, M Teresa Blay, Ximena Terra, Gary Frost, Montserrat Pinent, Anna Ardévol Tags: Research Article Source Type: research

Fat ‐Shaped Microbiota Affects Lipid Metabolism, Liver Steatosis, and Intestinal Homeostasis in Mice Fed a Low‐Protein Diet
ConclusionThe transplant of HFM in mice fed a low ‐protein diet represents a noxious stimulus for the ileal mucosa and impairs hepatic lipoprotein secretion, favoring the occurrence of hepatic microvesicular steatosis. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 1, 2020 Category: Food Science Authors: Marco Busnelli, Stefano Manzini, Amin Jablaoui, Aur élia Bruneau, Aïcha Kriaa, Catherine Philippe, Francesca Arnaboldi, Alice Colombo, Benedetta Ferrari, Federico Ambrogi, Emmanuelle Maguin, Moez Rhimi, Giulia Chiesa, Philippe Gérard Tags: Research Article Source Type: research

Resveratrol Alleviates Endoplasmic Reticulum Stress –Associated Hepatic Steatosis and Injury in Mice Challenged with Tunicamycin
ConclusionRSV may have an auxiliary therapeutic potential to prevent the development of steatosis and its progression to steatohepatitis in the liver by alleviating severe ER stress. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 28, 2020 Category: Food Science Authors: Yanan Chen, Hao Zhang, Yueping Chen, Yuying Zhang, Mingming Shen, Peilu Jia, Shuli Ji, Tian Wang Tags: Research Article Source Type: research

Natural Xanthone α‐Mangostin Inhibits LPS‐Induced Microglial Inflammatory Responses and Memory Impairment by Blocking the TAK1/NF‐κB Signaling Pathway
Conclusionα‐M inhibits microglia‐mediated neuroinflammation and prevents neurotoxicity and memory impairment from inflammatory damage. These results indicate that α‐M has great potential to be used as a nutritional preventive strategy for neuroinflammation‐related neurodegenerative disorders such as Alzheimer's disease. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 28, 2020 Category: Food Science Authors: Huifeng Guan, Jiabing Li, Xiaofang Tan, Shenying Luo, Yangdan Liu, Yiwen Meng, Baichuan Wu, Yan Zhou, Yang Yang, Hongzhuan Chen, Lina Hou, Yu Qiu, Juan Li Tags: Research Article Source Type: research

Scavenger Receptor class B type I is Required for 25 ‐Hydroxycholecalciferol Cellular Uptake and Signaling in Myeloid Cells
ConclusionIn conclusion, SR ‐B1 plays a critical role in vitamin D3 biology, paving the way for novel therapeutic interventions.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 25, 2020 Category: Food Science Authors: Shirley Tenesaca, Marcos Vasquez, Myriam Fernandez ‐Sendin, Claudia Augusta Di Trani, Nuria Ardaiz, Celia Gomar, Doina Cuculescu, Maite Alvarez, Itziar Otano, Ignacio Melero, Pedro Berraondo Tags: Research Article Source Type: research

Front Cover: Ameliorating Activity of Ishige okamurae on the Amyloid Beta –Induced Cognitive Deficits and Neurotoxicity through Regulating ERK, p38 MAPK, and JNK Signaling in Alzheimer's Disease–Like Mice Model
Mol. Nutr. Food Res. 2020,64,https://doi.org/10.1002/mnfr.2019012201901220DOI:10.1002/mnfr.201901220By using an Alzheimer's disease (AD) ‐like mice model, Oh Yun Kwon and Seung Ho Lee demonstrate that oral administration ofIshige okamurae extract (IOE) attenuates amyloid beta peptide –mediated cognitive deficits and neuronal toxicity through inhibition of abnormal activation of mitogen‐activated protein kinase (MAPK). The study, described in articlehttps://doi.org/10.1002/mnfr.2019012201901220, suggests that IOE could be developed as a potential anti ‐AD agent. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 24, 2020 Category: Food Science Authors: Oh Yun Kwon, Seung Ho Lee Tags: Front Cover Source Type: research

Editorial Board: Mol. Nutr. Food Res. 12'20
Molecular Nutrition& Food Research, Volume 64, Issue 12, June 2020. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 24, 2020 Category: Food Science Tags: Editorial Board Source Type: research

Fat ‐Shaped Microbiota Affects Lipid Metabolism, Liver Steatosis and Intestinal Homeostasis in Mice Fed a Low‐Protein Diet
ConclusionThe transplant of HFM in mice fed a low ‐protein diet represents a noxious stimulus for the ileal mucosa and impairs hepatic lipoprotein secretion, favoring the occurrence of hepatic microvesicular steatosis.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 24, 2020 Category: Food Science Authors: Marco Busnelli, Stefano Manzini, Amin Jablaoui, Aur élia Bruneau, Aïcha Kriaa, Catherine Philippe, Francesca Arnaboldi, Alice Colombo, Benedetta Ferrari, Federico Ambrogi, Emmanuelle Maguin, Moez Rhimi, Giulia Chiesa, Philippe Gérard Tags: Research Article Source Type: research

A Short ‐Term Western Diet Impairs Cholesterol Homeostasis and Key Players of Beta Amyloid Metabolism in Brain of Middle Aged Rats
ConclusionsOverall these data show that a western diet is associated with perturbation of cholesterol homeostasis in middle aged rats, mostly in hippocampus. This might prime molecular events involved in the onset of neurodegenerative diseases.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 24, 2020 Category: Food Science Authors: Maria Stefania Spagnuolo, Valentina Pallottini, Arianna Mazzoli, Lucia Iannotta, Claudia Tonini, Barbara Morone, Marcus St åhlman, Raffaella Crescenzo, Maria Strazzullo, Susanna Iossa, Luisa Cigliano Tags: Research Article Source Type: research

Microbial Products and Metabolites Contributing to Alcohol ‐Related Liver Disease
This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 24, 2020 Category: Food Science Authors: Bei Gao, Atoosa Emami, Shilpa Nath, Bernd Schnabl Tags: Review Source Type: research

Mitochondrial Dysfunction is a Key Pathway that Links Saturated Fat Intake to the Development and Progression of NAFLD
This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 23, 2020 Category: Food Science Authors: Ruth C.R. Meex, Ellen E. Blaak Tags: Review Source Type: research

Prenatal High ‐Salt Diet–Induced Metabolic Disorders via Decreasing Peroxisome Proliferator–Activated Receptor Gamma Coactivator 1α in Adult Male Rat Offspring
ConclusionThese findings suggest that prenatal HS intake induces metabolic disorders via the decreased expression of Ppargc1a in the skeletal muscle of adult offspring, providing novel information concerning the mechanisms and early prevention of metabolic diseases of fetal origins. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 22, 2020 Category: Food Science Authors: Yanping Liu, Chunli Yang, Xueqin Feng, Linglu Qi, Jun Guo, Dan Zhu, Phung N. Thai, Yingying Zhang, Pengjie Zhang, Miao Sun, Juanxiu Lv, Lubo Zhang, Zhice Xu, Xiyuan Lu Tags: Research Article Source Type: research

Discovery of Intake Biomarkers of Lentils, Chickpeas, and White Beans by Untargeted LC –MS Metabolomics in Serum and Urine
ConclusionsThe results of the present untargeted metabolomics work reveals a broad list of metabolites that are candidates for use as biomarkers of pulse intake. Further studies are needed to validate these BFIs and to find the best combinations of them to boost their specificity. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 22, 2020 Category: Food Science Authors: Mar Garcia ‐Aloy, Marynka Ulaszewska, Pietro Franceschi, Sheila Estruel‐Amades, Christoph H. Weinert, Alba Tor‐Roca, Mireia Urpi‐Sarda, Fulvio Mattivi, Cristina Andres‐Lacueva Tags: Research Article Source Type: research

Impact of Phenol ‐Enriched Virgin Olive Oils on the Postprandial Levels of Circulating microRNAs Related to Cardiovascular Disease
ConclusionsDuring the postprandial state, the levels of let ‐7e‐5p decreased with EVOO regardless of polyphenol content suggesting a general response to the fatty acid composition of EVOO or/and the presence of at least 250 mg polyphenol/kg olive oil. Moreover, the miR‐17‐92 cluster increased by low and medium polyphenol content suggesting a role in fatty acid metabolism and nutrient sensing. Thus, modulation of circulating microRNAs levels could be a potential mechanism for the cardiovascular benefits associated with EVOO intake.This article is protected by copyright. All rights reserved (Source: Molecular Nu...
Source: Molecular Nutrition and Food Research - June 20, 2020 Category: Food Science Authors: Lidia Daimiel, V íctor Micó, Rosa M Valls, Anna Pedret, M José Motilva, Laura Rubió, Montse Fitó, Marta Farrás, María‐Isabel Covas, Rosa Solá, José M Ordovás Tags: Research Article Source Type: research

Gluten ‐free Diet in IBD: Time for a Recommendation?
This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 19, 2020 Category: Food Science Authors: Kimberly N. Weaver, Hans Herfarth Tags: Review Source Type: research

Mass Spectrometry –Based Analysis of Urinary Biomarkers for Dietary Tomato Intake
ConclusionsThe dietary intake of tomato juice is conclusively traceable based on urinary excretion of multiple β‐carboline, imidazole, and steroidal alkaloids, and can be determined for up to 48 h after consumption. Furthermore, different intake doses can clearly be distinguished based on their urinary excretion. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 18, 2020 Category: Food Science Authors: Yannick H övelmann, Lea Lewin, Katharina Steinert, Florian Hübner, Hans‐Ulrich Humpf Tags: Research Article Source Type: research

Microbiome Transfer Partly Overrides Lack of IL ‐1RI Signalling to Alter Hepatic but not Adipose Tissue Phenotype and Lipid Handling following a High‐Fat Diet Challenge
ConclusionTransfer of SCFA ‐producing microbiota from IL‐1RI−/− mice highlights a new connection between diet, inflammatory signalling and the gut microbiome, an association that is dependent on the nature of the dietary fat challenge.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 18, 2020 Category: Food Science Authors: Jessica C. Ralston, Kathleen A.J. Mitchelson, Gina M. Lynch, Tam T.T. Tran, Hao Wang, Conall R. Strain, Yvonne M. Lenighan, Elaine B. Kennedy, Catherine Stanton, Fiona C. McGillicuddy, Qiaozhu Su, Paul W. O'Toole, Helen M. Roche Tags: Research Article Source Type: research

Dietary Fiber from Oat and Rye Brans Ameliorate Western Diet –Induced Body Weight Gain and Hepatic Inflammation by the Modulation of Short Chain Fatty Acids, Bile Acids, and Tryptophan Metabolism
ConclusionsBoth brans developed a favorable environment in the gut by altering the composition of microbes and modulating produced metabolites. Changes induced in the gut environment by a fiber ‐enriched diet may explain the amelioration of metabolic disturbances related to WD.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 11, 2020 Category: Food Science Authors: Zuzanna Maria Kundi, Jetty Chung ‐Yung Lee, Jussi Pihlajamäki, Chi Bun Chan, Kin Sum Leung, Stephanie Sik Yu So, Emilia Nordlund, Marjukka Kolehmainen, Hani El‐Nezami Tags: Research Article Source Type: research

Reduction in Circulating Advanced Glycation End Products by Mediterranean Diet is Associated with Increased Likelihood of type 2 Diabetes Remission in Patients with Coronary Heart Disease: From the Cordioprev Study
Conclusions: We have demonstrated that the reduction of serum AGEs levels and the modulation of its metabolism, occurring after the consumption of a Mediterranean diet, might be involved in the molecular mechanism underlying the T2DM remission of newly ‐diagnosed patients with coronary heart disease.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 11, 2020 Category: Food Science Authors: Francisco M. Gutierrez ‐Mariscal, Magdalena P. Cardelo, Silvia la Cruz, Juan F Alcala‐Diaz, Irene Roncero‐Ramos, Ipek Guler, Cristina Vals‐Delgado, Alejandro López‐Moreno, Raul M. Luque, Javier Delgado‐Lista, Pablo Perez‐Martinez, Tags: Research Article Source Type: research

Resveratrol Alleviates Endoplasmic Reticulum Stress ‐Associated Hepatic Steatosis and Injury in Mice Challenged with Tunicamycin
ConclusionRSV may have an auxiliary therapeutic potential to prevent the development of steatosis and its progression to steatohepatitis in the liver by alleviating severe ER stress.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 11, 2020 Category: Food Science Authors: Yanan Chen, Hao Zhang, Yueping Chen, Yuying Zhang, Mingming Shen, Peilu Jia, Shuli Ji, Tian Wang Tags: Research Article Source Type: research

Train to Lose: Innate Immune Memory in Metaflammation
This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 11, 2020 Category: Food Science Authors: Hugo Charles ‐Messance, Frederick J. Sheedy Tags: Review Source Type: research

Unconnected Body Accrual of Dietary Lipid and Protein in Rats Fed Diets with Different Lipid and Protein Content
ConclusionsDifferent diets produced substantial changes in the fate of ingested nutrient energy. Dietary lipids were not essential for sustaining increases in body lipid (or adipose tissue) content. Body protein accrual was unrelated to dietary lipids and overall energy intake. Both protein and lipid accrual were more efficient in male than in female rats.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 10, 2020 Category: Food Science Authors: Laia Oliva, Tania Aranda, Mari à Alemany, José‐Antonio Fernández‐López, Xavier Remesar Tags: Research Article Source Type: research

Chronic Stress Potentiates High Fructose –Induced Lipogenesis in Rat Liver and Kidney
ConclusionLiquid high ‐fructose supplementation increases IHTG and VLDL‐TG secretion after the feeding phase, the latter being the result of stimulated hepatic and renal DNL. Chronic stress potentiates the effects of high fructose on fDNL and export of newly synthesized VLDL‐TGs, and decreases fructose‐induced in trahepatic TG accumulation after the feeding phase. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 9, 2020 Category: Food Science Authors: Danijela Vojnovi ć Milutinović, Jelena Brkljačić, Ana Teofilović, Biljana Bursać, Marina Nikolić, Ljupka Gligorovska, Sanja Kovačević, Ana Djordjevic, Frederic Preitner, Luc Tappy, Gordana Matić, Nataša Veličković Tags: Research Article Source Type: research

A Natural Xanthone α‐Mangostin Inhibits LPS‐Induced Microglial Inflammatory Responses and Memory Impairment by Blocking the TAK1/NF‐κB Signaling Pathway
Conclusionα‐M inhibits microglia‐mediated neuroinflammation and prevents neurotoxicity and memory impairment from inflammatory damage. These results indicate that α‐M has great potential to be used as a nutritional preventive strategy for neuroinflammation‐related neurodegenerative disorders such as Alzheimer's disease.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 7, 2020 Category: Food Science Authors: Huifeng Guan, Jiabing Li, Xiaofang Tan, Shenying Luo, Yangdan Liu, Yiwen Meng, Baichuan Wu, Yan Zhou, Yang Yang, Hongzhuan Chen, Lina Hou, Yu Qiu, Juan Li Tags: Research Article Source Type: research

Prenatal High ‐Salt Diet Induced Metabolic Disorders Via Decreasing Peroxisome Proliferator‐Activated Receptor Gamma Coactivator 1α in Adult Male Rat Offspring
ConclusionThese findings suggest that prenatal HS intake induces metabolic disorders via the decreased expression of Ppargc1a in skeletal muscle of adult offspring, providing novel information concerning the mechanisms and early prevention of metabolic diseases of fetal origins.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 7, 2020 Category: Food Science Authors: Yanping Liu, Chunli Yang, Xueqin Feng, Linglu Qi, Jun Guo, Dan Zhu, Phung N. Thai, Yingying Zhang, Pengjie Zhang, Miao Sun, Juanxiu Lv, Lubo Zhang, Zhice Xu, Xiyuan Lu Tags: Research Article Source Type: research

Bone ‐specific Metabolism of Dietary Polyphenols in Resorptive Bone Diseases
ScopeCurcumin prevents bone loss in resorptive bone diseases and inhibits osteoclast formation, a key process driving bone loss. Curcumin circulates as an inactive glucuronide that can be deconjugated in situ by bone's high β‐glucuronidase (GUSB) content, forming the active aglycone. Because curcumin is a common remedy for musculoskeletal disease, effects of microenvironmental changes consequent to skeletal development and/or disease on bone curcumin metabolism were explored.Methods and resultsAcross sexual/skeletal development or between sexes in C57BL/6 mice ingesting curcumin (500  mg/kg), bone curcumin meta...
Source: Molecular Nutrition and Food Research - June 7, 2020 Category: Food Science Authors: Andrew G Kunihiro, Paula B Luis, Jennifer B Frye, Wade Chew, H ‐H. Sherry Chow, Claus Schneider, Janet L Funk Tags: Research Article Source Type: research

Interaction Between Tea Polyphenols and Intestinal Microbiota in Host Metabolic Diseases from the Perspective of the Gut ‐Brain Axis
This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 7, 2020 Category: Food Science Authors: Ruonan Yan, Chi ‐Tang Ho, Xin Zhang Tags: Review Source Type: research