HSP22 (HSPB8) positively regulates PGF2 α-induced synthesis of interleukin-6 and vascular endothelial growth factor in osteoblasts
Heat shock protein 22 (HSP22) belongs to class I of the small HSP family that displays ubiquitous expression in osteoblasts. We previously demonstrated that prostaglandin F2 α (PGF2α), a potent bone remodeling ... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 21, 2021 Category: Orthopaedics Authors: Gen Kuroyanagi, Go Sakai, Takanobu Otsuka, Naohiro Yamamoto, Kazuhiko Fujita, Tetsu Kawabata, Rie Matsushima-Nishiwaki, Osamu Kozawa and Haruhiko Tokuda Tags: Research article Source Type: research

Unilateral percutaneous vertebroplasty for osteoporotic lumbar compression fractures: a comparative study between transverse process root-pedicle approach and conventional transpedicular approach
Percutaneous vertebroplasty (PVP) is a routine operation for the treatment of osteoporotic lumbar compression fractures (OLCFs). As is well known, unilateral puncture is a common method. However, with the conv... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 21, 2021 Category: Orthopaedics Authors: Wenwu Zhang, Shenpeng Liu, Xianhua Liu, Xiang Li, Le Wang and Yong Wan Tags: Research article Source Type: research

Effects of exogenous nerve growth factor on the expression of BMP-9 and VEGF in the healing of rabbit mandible fracture with local nerve injury
Mandibular fracture healing is a complex process involving nerves and growth factors. Nerve growth factor (NGF) not only facilitates the maintenance of sympathetic neurite growth but also stimulates other grow... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 21, 2021 Category: Orthopaedics Authors: Sen Yang, Jiao Cheng, Cheng Man, Lian Jiang, Guogeng Long, Wenjun Zhao and Dexin Zheng Tags: Research article Source Type: research

miRNA-128 modulates bone neoplasms cells proliferation and migration through the WNT/ β-catenin and EMT signal pathways
Bone neoplasms present poor prognosis due to recurrence and metastasis. Although the role microRNAs (miRNAs) in inhibiting growth and metastasis of bone neoplasms has been investigated, the underlying potentia... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 20, 2021 Category: Orthopaedics Authors: Yang Li, Xiaotao Long, Ji Wang, Jing Peng and Kai Shen Tags: Research article Source Type: research

Case series and finite element analysis of PFNA combined with cerclage wire for treatment of subtrochanteric fracture of femur
To retrospectively analyze the clinical efficacy of PFNA combined with a cerclage wire in the treatment of 52 patients with unstable subtrochanteric fracture of the femur and to analyze the biomechanical effec... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 20, 2021 Category: Orthopaedics Authors: Xiaowei Huang, Fangxue Zhang and Yong Zhang Tags: Research article Source Type: research

Bioinformatics analysis of miRNA and mRNA expression profiles to reveal the key miRNAs and genes in osteoarthritis
This study aimed to identify the key miRNAs and genes associated with OA progression. (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 19, 2021 Category: Orthopaedics Authors: Pei-yan Huang, Jun-guo Wu, Jun Gu, Tie-qi Zhang, Ling-feng Li, Si-qun Wang and Minghai Wang Tags: Research article Source Type: research

Elevated expression of MMP8 and MMP9 contributes to diabetic osteoarthritis progression in a rat model
Knowledge regarding the pathogenesis of osteoarthritis (OA) is very limited. Previous studies have shown that matrix metalloproteinase (MMP) 8 and MMP9 were upregulated in patients with diabetic OA. However, t... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 19, 2021 Category: Orthopaedics Authors: Simin Luo, Wuji Li, Wenrui Wu and Qiping Shi Tags: Research article Source Type: research

Difference in the early postoperative change of the joint line convergence angle between opening wedge and closed wedge high tibial osteotomies
The purpose of this study was to investigate the correction error associated with soft tissue balance in high tibial osteotomy (HTO) and the difference between opening wedge HTO (OWHTO) and closed wedge HTO (C... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 19, 2021 Category: Orthopaedics Authors: Ken Kumagai, Hiroshi Fujimaki, Shunsuke Yamada, Shuntaro Nejima, Joji Matsubara and Yutaka Inaba Tags: Research article Source Type: research

Malalignment and distal contact of short tapered stems could be associated with postoperative thigh pain in primary total hip arthroplasty
Short tapered stem placement has been extensively employed in total hip arthroplasty (THA). Suboptimal fixation tends to cause postoperative complications, such as thigh pain. However, it remains unclear wheth... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 19, 2021 Category: Orthopaedics Authors: Zhijie Chen, Bin Li, Kaizhe Chen, Jianmin Feng, Yi Wang, Zhihong Liu and Chuan He Tags: Research article Source Type: research

Combined antegrade femur lengthening and distal deformity correction: a case series
This study aims to report a new technique for simultaneous limb lengthening and acute distal femoral ... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 15, 2021 Category: Orthopaedics Authors: Achraf Jardaly and Shawn R. Gilbert Tags: Research article Source Type: research

The efficacy and safety of high-dose tranexamic acid in adolescent idiopathic scoliosis: a meta-analysis
This study aimed to evaluate the efficacy and safety of using high-dose intravenous tranexamic acid (TXA) to reduce blood loss in idiopathic scoliosis surgery. (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 14, 2021 Category: Orthopaedics Authors: Indra K. Shrestha, Tian-Yi Ruan, Lan Lin, Miao Tan, Xue-Qing Na, Qi-Cai Qu, Jian-Chun Chen, Yong-Yu Si and Jian-Ping Tao Tags: Research article Source Type: research

Treatment of femoral neck fractures: sliding hip screw or cannulated screws? A meta-analysis
Femoral neck fractures are still unsolved problems nowadays; sliding hip screw (SHS) and cannulated compression screw (CCS) are the most commonly used devices. We evaluated the clinical outcomes and complicati... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 14, 2021 Category: Orthopaedics Authors: Yutong Xia, Wendong Zhang, Zhen Zhang, Jingcheng Wang and Lianqi Yan Tags: Systematic review Source Type: research

Low expression of miR-142-3p promotes intervertebral disk degeneration
Intervertebral disk degeneration (IDD) is a degenerative disease characterized by cytoplasm loss and extracellular matrix degradation. Numerous evidence reported that miRNAs participated in IDD development. Ne... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 14, 2021 Category: Orthopaedics Authors: Jianmin Xue, Baoyang Hu, Wenhua Xing, Feng Li, Zhi Huang, Wenkai Zheng, Bo Wang, Yong Zhu and Xuejun Yang Tags: Research article Source Type: research

Proliferation ability of particulated juvenile allograft cartilage
Particulated juvenile allograft cartilage (PJAC) has a good short-term clinical efficacy in repairing articular cartilage defects, but the proliferation ability of PJAC and the biological characteristics of tr... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 14, 2021 Category: Orthopaedics Authors: Changgui Zhang, Xingyu Zhao, Yunong Ao, Jin Cao, Liu Yang and Xiaojun Duan Tags: Research article Source Type: research

A guideline for screw fixation of coracoid process base fracture by 3D simulation
This study was performed to simulate th... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 14, 2021 Category: Orthopaedics Authors: Zhongye Sun, Hao Li, Bei Wang, Jun Yan, Liren Han, Shizhang Han, Xiaofei Yang and Bei Zhao Tags: Research article Source Type: research

Circular RNA circ_0081001 knockdown enhances methotrexate sensitivity in osteosarcoma cells by regulating miR-494-3p/TGM2 axis
Circular RNAs (circRNAs) have been shown to participate in the chemoresistance and tumorigenesis of multiple cancers. The purpose of this research was to investigate the function of circ_0081001 in methotrexat... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 13, 2021 Category: Orthopaedics Authors: Wei Wei, Liefeng Ji, Wanli Duan and Jiang Zhu Tags: Research article Source Type: research

Nerve growth factor-chondroitin sulfate/hydroxyapatite-coating composite implant induces early osseointegration and nerve regeneration of peri-implant tissues in Beagle dogs
Osseointegration is the premise of the chewing function of dental implant. Nerve growth factor (NGF), as a neurotrophic factor, can induce bone healing. However, the influence of NGF-chondroitin sulfate (CS)/h... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 13, 2021 Category: Orthopaedics Authors: Jun Ye, Bo Huang and Ping Gong Tags: Research article Source Type: research

Utilisation of distally based sural fasciocutaneous flaps in lower extremity reconstruction: a single-centre experience with 88 paediatric patients
No large series have analysed distally based sural fasciocutaneous (DBSF) flaps in paediatric patients. The aims of this study were to assess the reliability and analyse the potential risk factors for these fl... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 13, 2021 Category: Orthopaedics Authors: Zhaobiao Luo, Jiangdong Ni, Guohua Lv, Jianwei Wei, Lihong Liu, Ping Peng and Zhonggen Dong Tags: Research article Source Type: research

Distribution of the T12 erector spinal muscle plane block in the dorsal region guided by ultrasound
This study aimed to explore the distribution of the erector spinal muscle plane block of the thoracic 12 vertebral body (T12) in the dorsal region guided by ultrasound. (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 12, 2021 Category: Orthopaedics Authors: Jin-Feng Zhang, Wei-Wei Zhang, Jia Wang, Hao Guo and Ting Wang Tags: Research article Source Type: research

Influence of SCA on clinical outcomes and cervical alignment after laminoplasty in patients with multilevel cervical spondylotic myelopathy
To study the impact of changes in spino-cranial angle (SCA) on sagittal alignment and to investigate the relationship between SCA and Neck Disability Index (NDI) scores after laminoplasty (LP) (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 12, 2021 Category: Orthopaedics Authors: Zheng Wang, Zhi-Wei Wang, Xi-Wen Fan, Zhen Liu, Jia-Yuan Sun, Wen-Yuan Ding and Da-Long Yang Tags: Research article Source Type: research

miR-107 affects cartilage matrix degradation in the pathogenesis of knee osteoarthritis by regulating caspase-1
This study aimed to investigate whether miR-107 could regulate KOA through pyroptosis to affect collagen protein secreted by cho... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 11, 2021 Category: Orthopaedics Authors: Jiatian Qian, Peiliang Fu, Shiao Li, Xiang Li, Yancheng Chen and Zhenen Lin Tags: Research article Source Type: research

What is the impact of infrapopliteal endovascular intervention on free flap survival in diabetic foot reconstruction?
The combination of endovascular intervention and microvascular free flap transfer has been effectively used for chronic ischemic wounds of lower limb. The aim of this study was to determine the influence of an... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 11, 2021 Category: Orthopaedics Authors: Duy Quang Thai, Dong Hwan Lee, Woo Beom Lee, Hyung Min Hahn and Il Jae Lee Tags: Research article Source Type: research

Total hip arthroplasty through the direct anterior approach with and without the use of a traction table: a matched-control, retrospective, single-surgeon study
Hip surgeons performing total hip arthroplasty (THA) through the direct anterior approach (DAA) commonly use a traction table to facilitate exposure. Even though performing THA through DAA without a traction t... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 11, 2021 Category: Orthopaedics Authors: Diane Wernly, Julien Wegrzyn, Geoffroi Lallemand, Jaad Mahlouly, Christophe Tissot and Alexander Antoniadis Tags: Research article Source Type: research

Comparison of postoperative effectiveness of less invasive short external rotator sparing approach versus standard posterior approach for total hip arthroplasty
Most of the studies assessing the corrective posterior total hip arthroplasty (THA) mainly focused on the mini-incision approach. Studies exploring the short external rotator sparing approach are rare. Therefo... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 11, 2021 Category: Orthopaedics Authors: Tianbao Wang, Yongwei Zhou, Xiaofei Li, Siqi Gao and Qining Yang Tags: Research article Source Type: research

Cephalo-medullary nailing versus dynamic hip screw with trochanteric stabilisation plate for the treatment of unstable per-trochanteric hip fractures: a meta-analysis
The use of cephalo-medullary nails (CMN) is a widely accepted management option for the treatment of unstable per-trochanteric hip fractures. A growing body of literature has reported good functional and radio... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 11, 2021 Category: Orthopaedics Authors: Amr Selim, Nikhil Ponugoti, Ali Zain Naqvi and Henry Magill Tags: Systematic review Source Type: research

Common variants in MAEA gene contributed the susceptibility to osteoporosis in Han Chinese postmenopausal women
Osteoporosis (OP) is a complex bone metabolism disorder characterized by the loss of bone minerals and an increased risk of bone fracture. A recent study reported the relationship of the macrophage erythroblas... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 10, 2021 Category: Orthopaedics Authors: Xuan Cai, Jun Dong, Teng Lu, Liqiang Zhi and Xijing He Tags: Research article Source Type: research

A novel surgical approach and technique and short-term clinical efficacy for the treatment of proximal humerus fractures with the combined use of medial anatomical locking plate fixation and minimally invasive lateral locking plate fixation
The typical anterolateral approach is widely used to treat proximal humerus fractures with lateral locking fixation. However, lateral fixation cannot completely avoid medial reduction loss and varus deformity ... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 9, 2021 Category: Orthopaedics Authors: Fu Wang, Yan Wang, Jinye Dong, Yu He, Lianxin Li, Fanxiao Liu and Jinlei Dong Tags: Research article Source Type: research

Reliability of circulating fibrinogen in the diagnosis of prosthesis-related infections: a systematic review and meta-analysis
Fibrinogen (FIB) has recently been used as a biomarker to diagnose periprosthetic joint infection (PJI), but its reliability is still questionable. The aim of this study was to investigate the accuracy of FIB ... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 9, 2021 Category: Orthopaedics Authors: Xingyang Zhu, Haitao Zhang, Xiaobo Sun, Yijin Li, Jiahao Li, Yuqing Zeng, Peng Deng, Xinyu Qi, Jinlun Chen, Pengcheng Ye, Wenjun Feng, Jie Li, Jianchun Zeng and Yirong Zeng Tags: Research article Source Type: research

Determining the stability of minimally displaced lateral humeral condyle fractures in children: ultrasound is better than arthrography
Evaluating of the articular cartilage status of the distal humeral epiphysis is difficult. Ultrasound imaging of the elbow is increasingly being used to confirm the integrity of the articular cartilage of mini... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 9, 2021 Category: Orthopaedics Authors: Xing Wu, Xiongtao Li, Shaowei Yang, Si Wang, Jingdong Xia, Xiaoliang Chen and Xiantao Shen Tags: Research article Source Type: research

Mid-term outcomes of the R3 ™ delta ceramic acetabular system in total hip arthroplasty
Whilst bony fixation of hip replacement has stable solutions, there remains controversy over which bearing best optimizes longevity and function. Ceramic-on-ceramic (CoC) bearing combinations are associated wi... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 9, 2021 Category: Orthopaedics Authors: Edward T. Davis, Ville Remes, Petri Virolainen, Peter Gebuhr, Bart Van Backl é, Matthew P. Revell and Branko Kopjar Tags: Research article Source Type: research

Wrist tuberculosis-experience from eighteen cases: a retrospective study
In this study, the clinical manifestations, diagnosis, treatment, and prognosis of 18 ca... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 9, 2021 Category: Orthopaedics Authors: Longfei Zou, Xing Guo, Hao Xue, Denghua Huang, Hui Lv and Meiyun Tan Tags: Research article Source Type: research

Intraoperative anti-inflammatory drugs combined with no drainage after MIS-TLIF in the treatment of recurrent lumbar disc herniation: an RCT
Minimally invasive-transforaminal lumbar interbody fusions (MIS-TLIF), in which the nerve root pain is caused by early postoperative edema reaction, is a common clinical complication. However, there is no effe... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 7, 2021 Category: Orthopaedics Authors: Jinpeng Du, Junsong Yang, Liang Yan, Lequn Shan, Wentao Wang, Yong Fan, Dingjun Hao and Dageng Huang Tags: Research article Source Type: research

Exosomal miR-186 derived from BMSCs promote osteogenesis through hippo signaling pathway in postmenopausal osteoporosis
Postmenopausal osteoporosis (PMO) that results from estrogen withdrawal is the most common primary osteoporosis among older women. However, little is known about the mechanism of PMO, and effective treatment o... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 7, 2021 Category: Orthopaedics Authors: Lu Li, Xin Zhou, Jun-tao Zhang, Ai-feng Liu, Chao Zhang, Jin-chang Han, Xiao-qing Zhang, Si Wu, Xiao-yu Zhang and Fu-quan Lv Tags: Research article Source Type: research

Are vitamin D and vitamin D receptor levels different in children with developmental dysplasia of the hip?
Developmental dysplasia of the hip (DDH) is a common disorder and associated with significant morbidity of the hip joint. Several risk factors have been identified for DDH. The aim of this study is to investig... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 7, 2021 Category: Orthopaedics Authors: Duran Topak, Muhammet Seyithano ğlu, Fatih Doğar, Ali Aydın Karadeniz, Burak Tanrıverdi, Fırat Ozan and Ökkeş Bilal Tags: Research article Source Type: research

Implants for trochanteric fractures in Norway: the role of the trochanteric stabilizing plate —a study on 20,902 fractures from the Norwegian hip fracture register 2011–2017
The trochanteric stabilizing plate (TSP) is used as an adjunct to the sliding hip screw (SHS) in unstable trochanteric and subtrochanteric fractures. We wanted to describe the choice of implant for trochanteri... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 7, 2021 Category: Orthopaedics Authors: Carl Erik Alm, Frede Frihagen, Eva Dybvik, Kjell Matre, Jan Erik Madsen and Jan-Erik Gjertsen Tags: Research article Source Type: research

Accuracy of intraoperative estimation of femoral stem anteversion in cementless total hip arthroplasty by using a digital protractor and a spirit level
The femoral component anteversion during surgery is traditionally assessed by a visual assessment of the surgeon and has proven to be imprecise. We sought to determine the accuracy of a digital protractor and ... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 7, 2021 Category: Orthopaedics Authors: Anuwat Pongkunakorn, Nawakun Phetpangnga and Narawit Kananai Tags: Research article Source Type: research

Knockdown of long non-coding RNA LEF1-AS1 attenuates apoptosis and inflammatory injury of microglia cells following spinal cord injury
Spinal cord injury (SCI) is associated with health burden both at personal and societal levels. Recent assessments on the role of lncRNAs in SCI regulation have matured. Therefore, to comprehensively explore t... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 6, 2021 Category: Orthopaedics Authors: Sheng-Yu Cui, Wei Zhang, Zhi-Ming Cui, Hong Yi, Da-Wei Xu, Wei Liu and Xin-Hui Zhu Tags: Research article Source Type: research

Intra-articular opening osteotomy combined with lateral ligament reconstruction for varus ankle arthritis
Takakura 3B ankle arthritis is featured as obliteration of ankle space with subchondral bone contact. Among these patients, some have medial distal tibial platform erosion. It is hard to treat this kind of pat... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 6, 2021 Category: Orthopaedics Authors: Yang Xu, Xing-chen Li, Chang-jun Guo and Xiang-yang Xu Tags: Research article Source Type: research

miR-1249-5p regulates the osteogenic differentiation of ADSCs by targeting PDX1
Osteoporosis (OP) is an age-related systemic bone disease. MicroRNAs (miRNAs) are involved in the regulation of osteogenic differentiation. The purpose of this study was to explore the role and mechanism of mi... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 6, 2021 Category: Orthopaedics Authors: Xiao-Mei Yang, Ya-Qi Song, Liang Li, Dong-Ming Liu and Guang-Dong Chen Tags: Research article Source Type: research

The impact of different artificial disc heights during total cervical disc replacement: an in vitro biomechanical study
The principles of choosing an appropriate implant height remain controversial in total cervical disc replacement (TDR). By performing an in vitro biomechanical study and exploring the biomechanical impact of i... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 6, 2021 Category: Orthopaedics Authors: Xiao-Fei Wang, Yang Meng, Hao Liu, Bei-Yu Wang and Ying Hong Tags: Research article Source Type: research

Direct comparison of 3D and 2D cultivation reveals higher osteogenic capacity of elderly osteoblasts in 3D
The aim of this study was the investigation of the osteogenic potential of human osteoblasts of advanced donor age in 2D and 3D culture. (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 6, 2021 Category: Orthopaedics Authors: Stephan Payr, Elizabeth Rosado-Balmayor, Thomas Tiefenboeck, Tim Schuseil, Marina Unger, Claudine Seeliger and Martijn van Griensven Tags: Research article Source Type: research

RETRACTED ARTICLE: Percutaneous pedicle screw fixation combined with selective transforaminal endoscopic decompression for the treatment of thoracolumbar burst fracture
The objective of this study was to evaluate the feasibility, safety, efficacy, and indications of percutaneous pedicle screw fixation (PPSF) combined with selective transforaminal endoscopic decompression (TED... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 5, 2021 Category: Orthopaedics Authors: Zhangheng Huang, Yuexin Tong, Zhiyi Fan, Chuan Hu and Chengliang Zhao Tags: Research article Source Type: research

The role of activating transcription factor 6 in hydroxycamptothecin-induced fibroblast autophagy and apoptosis
The over-proliferation of fibroblasts is considered to be the main cause of scar adhesion after joint surgery. Hydroxycamptothecin (HCPT), though as a potent antineoplastic drug, shows preventive effects on sc... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 4, 2021 Category: Orthopaedics Authors: Jin Tao, Hui Chen, Xiaolei Li and Jingcheng Wang Tags: Research article Source Type: research

Retrospective study on effectiveness of Activ L total disc replacement
The effectiveness of lumbar total disc replacement (TDR) with different prostheses for sagittal alignment has been reported previously. However, there are only few reports on Activ L TDR and no specific eviden... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 4, 2021 Category: Orthopaedics Authors: Wenzhi Sun, Peng Wang, Hailiang Hu, Chao Kong, Yong Hai and Shibao Lu Tags: Research article Source Type: research

Brachial-ankle pulse wave velocity is associated with the risk of osteoporosis: a cross-sectional evidence from a Chinese community-based cohort
Association of arterial stiffness and osteoporosis has been well documented in elderly population. However, it is not clear whether they co-progress from the early stages through common mechanisms. The object ... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 4, 2021 Category: Orthopaedics Authors: Kun Tang, Qiao Zhang, Nianchun Peng, Ying Hu, Shujing Xu, Miao Zhang, Rui Wang and Lixin Shi Tags: Research article Source Type: research

Identification of key pathways and hub genes in the myogenic differentiation of pluripotent stem cell: a bioinformatics and experimental study
The regeneration of muscle cells from stem cells is an intricate process, and various genes are included in the process such as myoD, mf5, mf6, etc. The key genes and pathways in the differentiating stages are... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 4, 2021 Category: Orthopaedics Authors: Wenyong Fei, Mingsheng Liu, Yao Zhang, Shichao Cao, Xuanqi Wang, Bin Xie and Jingcheng Wang Tags: Research article Source Type: research

Apoptosis of endplate chondrocytes in cervical kyphosis is associated with chronic forward flexed neck: an in vivo rat bipedal walking model
This study was undertaken to establish a rat bipedal walking model of cervical kyphosis (CK) associated with chronic forward flexed neck and assess the effects of chronic forward flexed neck on endplate chondr... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - January 4, 2021 Category: Orthopaedics Authors: Jinliang Lai, Guanglin Ji, Yuqiao Zhou, Jincai Chen, Min Zhou, Jianwen Mo and Tiansheng Zheng Tags: Research article Source Type: research

Retraction Note: Percutaneous pedicle screw fixation combined with selective transforaminal endoscopic decompression for the treatment of thoracolumbar burst fracture
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13018-020-01946-6. (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - December 30, 2020 Category: Orthopaedics Authors: Zhangheng Huang, Yuexin Tong, Zhiyi Fan, Chuan Hu and Chengliang Zhao Tags: Retraction Note Source Type: research

Correction to: The feasibility of short-segment Schanz screw implanted in an oblique downward direction for the treatment of lumbar 1 burst fracture: a finite element analysis
An amendment to this paper has been published and can be accessed via the original article. (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - December 24, 2020 Category: Orthopaedics Authors: Jifeng Liu, Sheng Yang, Fei Zhou, Jianmin Lu, Chunyang Xia, Huanhuan Wang and Chao Chen Tags: Correction Source Type: research

Incidence and locations of deep venous thrombosis of the lower extremity following surgeries of tibial plateau fractures: a prospective cohort study
To investigate the incidence of deep venous thrombosis (DVT) of the lower extremities following surgeries of tibial plateau fractures. (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - December 14, 2020 Category: Orthopaedics Authors: Junyong Li, Yanbin Zhu, Wei Chen, Kuo Zhao, Junzhe Zhang, Hongyu Meng, Zhucheng Jin, Dandan Ye and Yingze Zhang Tags: Research article Source Type: research