Long non-coding RNA GAS5 promotes cisplatin-chemosensitivity of osteosarcoma cells via microRNA-26b-5p/TP53INP1 axis
Osteosarcoma is a common malignant bone tumor. Cisplatin (DDP) achieves a high response rate in osteosarcoma. Here we aim to study the dysregulation of long non-coding RNA the growth arrest-specific transcript... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - November 22, 2023 Category: Orthopaedics Authors: Guowei Li and Xue Yan Tags: Research article Source Type: research

Effect of 10.6- μm CO2 laser moxibustion on the fastest 15-m walking time in patients with knee osteoarthritis: a double-blind, sham-controlled, multi-site randomized trial
In this study, we investigated the impact of 10.6- μm CO2 laser moxibustion (LM) on the fastest 15-m walking time in individuals suffering from knee osteoarthritis (KOA). (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - November 22, 2023 Category: Orthopaedics Authors: Lusheng Chen, Ling Zhao, Ke Cheng, Lin Lin, Fan Wu and Xueyong Shen Tags: Research article Source Type: research

Exosomal miR-331-3p derived from chemoresistant osteosarcoma cells induces chemoresistance through autophagy
Osteosarcoma is a common malignant bone tumor, and chemotherapy can effectively improve the prognosis. MicroRNA-331 (MiR-331) is associated with poor cancer outcomes. However, the role of miR-331 in osteosarco... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - November 22, 2023 Category: Orthopaedics Authors: Chenyang Meng, Yun Yang, Wei Feng, Penglei Ma and Rui Bai Tags: Research article Source Type: research

Efficacy and safety of platelet-rich plasma combined with Tai Chi for knee osteoarthritis: study protocol for a placebo-controlled randomized trial
No definitive treatment methods of curative for knee osteoarthritis (KOA). The combined therapies that into account both the biochemical and biomechanical may provide potential opportunities for treat KOA, and... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - November 21, 2023 Category: Orthopaedics Authors: Kun Yang, Yuwu Ding, Haichen Xu, Minghui Lai, Xueping Xu, Xiaoming Yu, Qian Deng and Liming Jiang Tags: Study Protocol Source Type: research

Association of central sensitization, visceral fat, and surgical outcomes in lumbar spinal stenosis
Controversy remains regarding predictors of surgical outcomes for patients with lumbar spinal stenosis (LSS). Pain sensitization may be an underlying mechanism contributing to LSS surgical outcomes. Further, o... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - November 21, 2023 Category: Orthopaedics Authors: Izaya Ogon, Hiroyuki Takashima, Tomonori Morita, Ryunosuke Fukushi, Tsuneo Takebayashi and Atsushi Teramoto Tags: Research article Source Type: research