Effect of Nutrition and Behavior Modification Program (NBMP) on maternal and neonatal outcomes among hyperglycemic mothers
CONCLUSIONS: The study's conclusions draw attention to the possible roles that maternal wellness, physical activity, and diet may have in reducing risks for both hyperglycemic mothers and their newborns. The NBMP resulted in higher adherence to lifestyle changes. Further research on a larger sample of hyperglycemic mothers is recommended to expand the generalizability of the findings.PMID:38639514 | DOI:10.26355/eurrev_202404_35903 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 19, 2024 Category: Drugs & Pharmacology Authors: P Premalatha H M A Maha H A Shadia V Krishnaraju K Prabahar N T Mathar Mohideen V Vinoth Prabhu B Prema R M Mashat E L Sampayan A E Hala A A Z Marwa G Kandasamy R Ahmed M A Mervat Source Type: research

Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Systematic Review and Network Meta-analysis for the American College of Physicians
CONCLUSION: In adults with T2DM, SGLT2 inhibitors and GLP1 agonists (but not DPP4 inhibitors, insulin, or tirzepatide) reduce all-cause mortality and MACE compared with usual care. SGLT2 inhibitors reduce CKD progression and heart failure hospitalization and GLP1 agonists reduce stroke compared with usual care. Serious adverse events and severe hypoglycemia are less frequent with SGLT2 inhibitors and GLP1 agonists than with insulin or SU.PRIMARY FUNDING SOURCE: American College of Physicians. (PROSPERO: CRD42022322129).PMID:38639549 | DOI:10.7326/M23-1490 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 19, 2024 Category: Internal Medicine Authors: Tyler Drake Adrienne Landsteiner Lisa Langsetmo Roderick MacDonald Maylen Anthony Caleb Kalinowski Kristen Ullman Charles J Billington Anjum Kaka Shahnaz Sultan Timothy J Wilt Source Type: research

Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Clinical Guideline From the American College of Physicians
Ann Intern Med. 2024 Apr 19. doi: 10.7326/M23-2788. Online ahead of print.ABSTRACTDESCRIPTION: The American College of Physicians (ACP) developed this clinical guideline to update recommendations on newer pharmacologic treatments of type 2 diabetes. This clinical guideline is based on the best available evidence for effectiveness, comparative benefits and harms, consideration of patients' values and preferences, and costs.METHODS: This clinical guideline is based on a systematic review of the effectiveness and harms of newer pharmacologic treatments of type 2 diabetes, including glucagon-like peptide-1 (GLP-1) agonists, a ...
Source: Annals of Internal Medicine - April 19, 2024 Category: Internal Medicine Authors: Amir Qaseem Adam J Obley Tatyana Shamliyan Lauri A Hicks Curtis S Harrod Carolyn J Crandall Clinical Guidelines Committee of the American College of Physicians Source Type: research

Pharmacologic Treatments in Adults With Type 2 Diabetes: Cost-Effectiveness and Comorbidity Considerations
Ann Intern Med. 2024 Apr 19. doi: 10.7326/M24-0861. Online ahead of print.NO ABSTRACTPMID:38639544 | DOI:10.7326/M24-0861 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 19, 2024 Category: Internal Medicine Authors: Fatima Z Syed Source Type: research

Annals Video Summary - Newer Pharmacologic Treatments in Adults With Type 2 Diabetes
Ann Intern Med. 2024 Apr 19:eM231554. doi: 10.7326/M23-1554. Online ahead of print.NO ABSTRACTPMID:38639543 | DOI:10.7326/M23-1554 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 19, 2024 Category: Internal Medicine Source Type: research

Visual Guideline - Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Visual Clinical Guideline From the American College of Physicians
Ann Intern Med. 2024 Apr 19:eM240803. doi: 10.7326/M24-0803. Online ahead of print.ABSTRACTThe purpose of this visual clinical guideline is to provide a visual summary of ACP's clinical guideline, "Newer Pharmacologic Treatments in Adults With Type 2 Diabetes." In addition, this visual clinical guideline features an interactive data visualization of findings associated with ACP's clinical recommendations for this topic.PMID:38639540 | DOI:10.7326/M24-0803 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 19, 2024 Category: Internal Medicine Source Type: research

Cost-Effectiveness of Newer Pharmacologic Treatments in Adults With Type 2 Diabetes: A Systematic Review of Cost-Effectiveness Studies for the American College of Physicians
CONCLUSION: Glucagon-like peptide-1 agonists and SGLT2i are of low value as first-line therapy but may be of intermediate value when added to metformin or other background therapy compared with adding nothing. Other drugs and comparisons are of low or uncertain value. Results are sensitive to drug effectiveness and cost assumptions.PRIMARY FUNDING SOURCE: American College of Physicians. (PROSPERO: CRD42022382315).PMID:38639547 | DOI:10.7326/M23-1492 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 19, 2024 Category: Internal Medicine Authors: John T Schousboe Adrienne Landsteiner Tyler Drake Shahnaz Sultan Lisa Langsetmo Anjum Kaka Maylen Anthony Charles J Billington Caleb Kalinowski Kristen Ullman Timothy J Wilt Source Type: research

Prevalence and associated risk factors of resistant hypertension among Chinese hypertensive patients in primary care setting
CONCLUSION: The prevalence of RHT among Chinese hypertensive patients in primary care setting of Hong Kong is 7.43%. RHT is more common in male patients, patients with longer duration of hypertension, concomitant T2DM and CHF. Clinicians should be vigilant when managing these groups of patients and provide aggressive treatment and close monitoring.PMID:38641566 | PMC:PMC11027357 | DOI:10.1186/s12875-024-02366-9 (Source: Primary Care)
Source: Primary Care - April 19, 2024 Category: Primary Care Authors: Kilpatrick Kiupak Chan Lapkin Chiang Clarence Chuenming Choi Yimchu Li Catherine Xiarui Chen Source Type: research

Effect of Nutrition and Behavior Modification Program (NBMP) on maternal and neonatal outcomes among hyperglycemic mothers
CONCLUSIONS: The study's conclusions draw attention to the possible roles that maternal wellness, physical activity, and diet may have in reducing risks for both hyperglycemic mothers and their newborns. The NBMP resulted in higher adherence to lifestyle changes. Further research on a larger sample of hyperglycemic mothers is recommended to expand the generalizability of the findings.PMID:38639514 | DOI:10.26355/eurrev_202404_35903 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 19, 2024 Category: Drugs & Pharmacology Authors: P Premalatha H M A Maha H A Shadia V Krishnaraju K Prabahar N T Mathar Mohideen V Vinoth Prabhu B Prema R M Mashat E L Sampayan A E Hala A A Z Marwa G Kandasamy R Ahmed M A Mervat Source Type: research

The Role of Left Ventricular Pressure-strain Loop in Evaluating Myocardial Work in Patients with Type 2 Diabetes
CONCLUSION: Pressure-strain loop technology can quantitatively, accurately, and sensitively monitor the variations in left ventricular myocardial contractile function of patients with T2D and detect subclinical cardiac injury at an early disease stage.PMID:38639632 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 19, 2024 Category: Complementary Medicine Authors: Xiaoxiao Yin Chao Sun Ruoling Han Juanjuan Li Yue Wen Source Type: research

The Role of Left Ventricular Pressure-strain Loop in Evaluating Myocardial Work in Patients with Type 2 Diabetes
CONCLUSION: Pressure-strain loop technology can quantitatively, accurately, and sensitively monitor the variations in left ventricular myocardial contractile function of patients with T2D and detect subclinical cardiac injury at an early disease stage.PMID:38639632 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 19, 2024 Category: Complementary Medicine Authors: Xiaoxiao Yin Chao Sun Ruoling Han Juanjuan Li Yue Wen Source Type: research

Blockbuster Obesity Drugs Have Potential New Uses
This Medical News story examines other potential uses of GLP-1 receptor agonists, the popular type 2 diabetes and weight-loss drugs. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research

Diabetic kidney disease screening status and related factors: a cross-sectional study of patients with type 2 diabetes in six provinces in China
To understand the awareness and practice of diabetic kidney disease (DKD) or nephropathy screening among community-based patients with type 2 diabetes in six provinces and cities in China, and to analyse the r... (Source: BMC Health Services Research)
Source: BMC Health Services Research - April 19, 2024 Category: General Medicine Authors: Zhang Xia, Xuechun Luo, Yanzhi Wang, Tingling Xu, Jianqun Dong, Wei Jiang and Yingying Jiang Tags: Research Source Type: research

Undiagnosed type 2 diabetes is common – intensified screening of established risk groups is imperative in Sweden: the SDPP cohort
Undiagnosed type 2 diabetes (T2D) is a global problem. Current strategies for diagnosis in Sweden include screening individuals within primary healthcare who are of high risk, such as those with hypertension, ... (Source: BMC Medicine)
Source: BMC Medicine - April 19, 2024 Category: Internal Medicine Authors: Hrafnhildur Gudjonsdottir, Per Tynelius, Nouha Saleh Stattin, Diego Yacam án Méndez, Anton Lager and Boel Brynedal Tags: Research article Source Type: research

The causality between Type 2 diabetes and breast cancer: a bidirectional two-sample Mendelian randomization study
Future Oncology, Ahead of Print. (Source: Future Oncology)
Source: Future Oncology - April 19, 2024 Category: Cancer & Oncology Authors: Lihan Zhang Shuochuan Liu Guangxing Yue Hong Niu Mengjin Hu Yuling Zheng Jingwen Tang Source Type: research