Health Technology Assessment: Evaluation of 7 Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Type 2 Diabetes Mellitus
(Source: Risk Management and Healthcare Policy)
Source: Risk Management and Healthcare Policy - April 23, 2024 Category: Health Management Tags: Risk Management and Healthcare Policy Source Type: research

The future burden of type 2 diabetes in Belgium: a microsimulation model
To forecast the annual burden of type 2 diabetes and related socio-demographic disparities in Belgium until 2030. (Source: Population Health Metrics)
Source: Population Health Metrics - April 23, 2024 Category: Epidemiology Authors: Elly Mertens, Junior Ocira, Diana Sagastume, Maria Salve Vasquez, Stefanie Vandevijvere and Jos é L. Peñalvo Tags: Research Source Type: research

Association between area-level walkability and glycated haemoglobin: a Portuguese population-based study
Diabetes poses a substantial disease burden, prompting preventive interventions. Physical inactivity, a major risk factor for type 2 diabetes, can potentially be mitigated by enhancing area-level walkability. ... (Source: BMC Public Health)
Source: BMC Public Health - April 23, 2024 Category: Consumer Health News Authors: Regina S á, Rita Roquette, Andrea Rebecchi, Judite Matias, Jorge Rocha, Maddalena Buffoli, Stefano Capolongo, Ana Isabel Ribeiro, Baltazar Nunes, Carlos Dias and Mafalda Sousa Uva Tags: Research Source Type: research

Association between onychomycosis and ulcerative complications in patients with diabetes: a longitudinal cohort study in Dutch general practice
Conclusions Onychomycosis significantly increased the risk of ulcer development in patients with DM in primary care, independently of other risk factors. In addition, onychomycosis increased the risk of surgeries and infectious complications. These results underscore the importance of giving sufficient attention to onychomycosis in primary care and corresponding guidelines. Early identification of onychomycosis during screening and routine care provides a good opportunity for timely recognition of increased ulcer risk. (Source: BMJ Open)
Source: BMJ Open - April 23, 2024 Category: General Medicine Authors: Watjer, R. M., Heckmans, K. M., Eekhof, J. A., Gummi, L., Quint, K. D., Numans, M. E., Bonten, T. N. Tags: Open access, Diabetes and Endocrinology Source Type: research

Long-Term effects of physical activity on weight loss, metabolic parameter and blood pressure in subjects undergoing bariatric surgery: a 5-year follow-up study.
bariatric surgery stands as an effective intervention for weight loss and improved metabolic control in obesity, although over time there is a proportion of weight regain and type-2-diabetes (T2D) relapse. Aims: to explore the role of physical activity (PA) after surgery and its impact on metabolic parameters during a 5-year follow-up. (Source: American Journal of Surgery)
Source: American Journal of Surgery - April 23, 2024 Category: Surgery Authors: Diego Moriconi, Laura Manca, Eleni Rebelos, Emanuele Guidotti, Linda Bonvicini, Antonio Troilo, Marco Anselmino, Monica Nannipieri Source Type: research

IJERPH, Vol. 21, Pages 522: Navigating Diabetes: Enhancing Self-Management through Education among Diabetic People at the Early Stages of the Disease & mdash;A Systematic Review
IJERPH, Vol. 21, Pages 522: Navigating Diabetes: Enhancing Self-Management through Education among Diabetic People at the Early Stages of the Disease—A Systematic Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph21050522 Authors: Kiçaj Saliaj Çerçizaj Prifti Qirko Rogozea Diabetes self-management education helps to improve health outcomes and qualities of life for diabetic patients. This systematic review examines the effectiveness of several types of diabetes self-management education for patients at the early stages of type 2 diabetes mellitu...
Source: International Journal of Environmental Research and Public Health - April 23, 2024 Category: Environmental Health Authors: Ki çaj Saliaj Çerçizaj Prifti Qirko Rogozea Tags: Systematic Review Source Type: research

Causal relationships of Helicobacter pylori and related gastrointestinal diseases on Type 2 diabetes: Univariable and Multivariable Mendelian randomization
ConclusionOur study found that H. pylori IgG antibody, H. pylori GroEL antibody, gastroduodenal ulcer and chronic gastritis are all related to t T2DM, and blood glucose level and obesity mediate the development of H. pylori GroEL antibody and gastroduodenal ulcer on T2DM, respectively. These findings may inform new prevention and intervention strategies for T2DM. (Source: PLoS One)
Source: PLoS One - April 23, 2024 Category: Biomedical Science Authors: Mei Sun Source Type: research

The Triglyceride-Glucose Index is Superior to Homeostasis Model Assessment of Insulin Resistance in predicting Metabolic Syndrome in an Adult Population in the United States
Metabolic syndrome (MetS) defined by a set of cardio-metabolic features is associated with an increased risk for atherosclerotic cardiovascular disease (ASCVD) and type 2 diabetes mellitus (T2DM)[1-3]. Its individual components include an elevated waist circumference [WC], increased triglycerides [TG], low levels of high density lipoprotein cholesterol [HDL-C], elevated fasting glucose and high blood pressure [1 –3]. It is a major global problem with no optimum treatment. (Source: Journal of Clinical Lipidology)
Source: Journal of Clinical Lipidology - April 23, 2024 Category: Lipidology Authors: Beverley Adams-Huet, Rafael Zubir án, Alan T Remaley, Ishwarlal Jialal Tags: Original Research Source Type: research

Association of KLOTHO gene variants with metabolic and renal function parameters in Mexican patients living with type 2 diabetes
ConclusionIn Mexican patients living with type 2 diabetes,KL variant rs9536314 was found associated with low odds of hypo-HDL cholesterol, albuminuria and presence of CKD. Meanwhile the consensus of soluble KLOTHO measurement is reached, genetic variants in theKL gene could be considered as genetic markers for CKD susceptibility in patients at high-risk of vascular complications. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 23, 2024 Category: Endocrinology Source Type: research

Efficacy of comprehensive structured exercise program on claudication pain and quality of life in type 2 diabetes mellitus with peripheral arterial disease
ConclusionIn the present study we found that comprehensive structured exercise program improves the arterial indices, quality of life, walking ability and reduces claudication pain in type 2 diabetes mellitus with peripheral arterial disease. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 23, 2024 Category: Endocrinology Source Type: research

Evaluating the efficacy and safety of weekly Insulin Icodec vs. Daily Insulin Glargine in type 2 Diabetes Mellitus: a systematic review and meta-analysis
ConclusionOnce-weekly Insulin Icodec demonstrates superior glycemic control with a reduced HbA1c compared to Once-Daily Insulin Glargine U100 while maintaining similar safety profiles. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 23, 2024 Category: Endocrinology Source Type: research

Cancers, Vol. 16, Pages 1625: The Use of Glucagon-like Peptide-1 Receptor Agonists in Patients with Type 2 Diabetes Mellitus Does Not Increase the Risk of Pancreatic Cancer: A U.S.-Based Cohort Study
Conclusion: The use of GLP-1 RAs in patients with type 2 diabetes mellitus (T2DM) does not appear to substantially elevate the risk of pancreatic cancer; in fact, it may potentially exert a protective effect. (Source: Cancers)
Source: Cancers - April 23, 2024 Category: Cancer & Oncology Authors: Mark Ayoub Carol Faris Tajana Juranovic Harleen Chela Ebubekir Daglilar Tags: Article Source Type: research

IJERPH, Vol. 21, Pages 517: The Association between Body Mass Index and Glycohemoglobin (HbA1c) in the US Population & rsquo;s Diabetes Status
IJERPH, Vol. 21, Pages 517: The Association between Body Mass Index and Glycohemoglobin (HbA1c) in the US Population’s Diabetes Status International Journal of Environmental Research and Public Health doi: 10.3390/ijerph21050517 Authors: Wenxue Lin Obesity, indicated by Body Mass Index (BMI), is a risk factor for type 2 diabetes. However, its association with glycated hemoglobin (HbA1c), a crucial indicator of blood-sugar control, may vary across different populations and disease statuses. Data from the National Health and Nutrition Examination Survey (NHANES) 2017–2018 were analyzed. Partic...
Source: International Journal of Environmental Research and Public Health - April 23, 2024 Category: Environmental Health Authors: Wenxue Lin Tags: Article Source Type: research

Choroidal vascularity index as a predictor for the development of retinopathy in diabetic patients
ConclusionsCVI tends to be lower in diabetic patients with or without DR compared to healthy controls. Moreover, patients with DR have a lower CVI than those without DR. CVI can be considered an early and sensitive biomarker for the onset of DR. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 22, 2024 Category: Endocrinology Source Type: research

Does gestational diabetes mellitus increase the risk of cardiovascular disease? A Mendelian randomization study
ConclusionWomen with a prior history of GDM face an elevated risk of future CAD. This increased risk of CAD cannot be solely attributed to the subsequent onset of diabetes. Regular CAD risk assessment and primary prevention strategies are of paramount importance for women with a history of GDM. (Source: Journal of Endocrinological Investigation)
Source: Journal of Endocrinological Investigation - April 22, 2024 Category: Endocrinology Source Type: research