Association of KLOTHO gene variants with metabolic and renal function parameters in Mexican patients living with type 2 diabetes

ConclusionIn Mexican patients living with type 2 diabetes,KL variant rs9536314 was found associated with low odds of hypo-HDL cholesterol, albuminuria and presence of CKD. Meanwhile the consensus of soluble KLOTHO measurement is reached, genetic variants in theKL gene could be considered as genetic markers for CKD susceptibility in patients at high-risk of vascular complications.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research