Senescent cells in human adipose tissue: A cross-sectional study
Obesity (Silver Spring). 2021 Jun 10. doi: 10.1002/oby.23202. Online ahead of print.ABSTRACTOBJECTIVE: Adipose tissue (AT) senescence is associated with AT dysfunction in rodents, but little is known about human AT senescence. The study goal was to define the distribution of senescent cells in two subcutaneous depots and understand relationships with adiposity and inflammation.METHODS: Sixty-three volunteers (48 females) underwent abdominal and femoral subcutaneous fat biopsies. Fat cell size, senescent cells using senescence-associated β-galactosidase staining per 100 nucleated cells (percentage), and mRNA expression...
Source: Obesity - June 11, 2021 Category: Eating Disorders & Weight Management Authors: Ana Elena Espinosa De Ycaza Esben S øndergaard Maria Morgan-Bathke Barbara Gisella Carranza Leon Kelli A Lytle Paola Ramos James L Kirkland Tamar Tchkonia Michael D Jensen Source Type: research

Obesity, Inflammatory and Thrombotic Markers, and Major Clinical Outcomes in Critically Ill Patients with COVID-19 in the US
CONCLUSIONS: In critically ill patients with COVID-19, higher BMI was not associated with death or thrombotic events but was associated with a greater risk of ARDS and AKI-RRT. The lack of an association between BMI and circulating biomarkers raises into question the paradigm that obesity contributes to poor outcomes in critically ill patients with COVID-19 by upregulating systemic inflammatory and prothrombotic pathways.PMID:34109768 | DOI:10.1002/oby.23245 (Source: Obesity)
Source: Obesity - June 10, 2021 Category: Eating Disorders & Weight Management Authors: Allon N Friedman John Guirguis Raj Kapoor Shruti Gupta David E Leaf Lava R Timsina STOP-COVID Investigators Source Type: research

Patient-provider discussions of bariatric surgery and subsequent weight changes and receipt of bariatric surgery
Obesity (Silver Spring). 2021 Jun 10. doi: 10.1002/oby.23183. Online ahead of print.ABSTRACTOBJECTIVE: The purpose of this study was to determine whether patients who discuss bariatric surgery with their providers are more likely to undergo the procedure and to lose weight.METHODS: A retrospective cohort study of adults with BMI ≥ 35 kg/m2 treated between 2000 and 2015 was conducted to analyze the relationship between a discussion of bariatric surgery in the first year after study entry and weight changes (primary outcome) and receipt of bariatric surgery (secondary outcome) over 2 years after study entry. Natural langu...
Source: Obesity - June 10, 2021 Category: Eating Disorders & Weight Management Authors: Lee-Shing Chang Shervin Malmasi Naoshi Hosomura Huabing Zhang C Justin Brown Victor J Lei Alexa Rubin Clara Ting Kimhouy Tong Maria Shubina Alexander Turchin Source Type: research

Intergenerational Educational Attainment and Cardiometabolic Health in Latino Individuals Living in the United States
CONCLUSIONS: IEA strongly patterns cardiometabolic health among Hispanic/Latino individuals living in the United States, suggesting that promotion of higher education is associated with reductions in obesity and MetS, potentially benefitting future generations of this population.PMID:34096684 | DOI:10.1002/oby.23156 (Source: Obesity)
Source: Obesity - June 7, 2021 Category: Eating Disorders & Weight Management Authors: Emma G Crenshaw Lindsay Fern ández-Rhodes Chantel L Martin Penny Gordon-Larsen Mary N Haan Allison E Aiello Source Type: research

Intergenerational Educational Attainment and Cardiometabolic Health in Latino Individuals Living in the United States
CONCLUSIONS: IEA strongly patterns cardiometabolic health among Hispanic/Latino individuals living in the United States, suggesting that promotion of higher education is associated with reductions in obesity and MetS, potentially benefitting future generations of this population.PMID:34096684 | DOI:10.1002/oby.23156 (Source: Obesity)
Source: Obesity - June 7, 2021 Category: Eating Disorders & Weight Management Authors: Emma G Crenshaw Lindsay Fern ández-Rhodes Chantel L Martin Penny Gordon-Larsen Mary N Haan Allison E Aiello Source Type: research

Intergenerational Educational Attainment and Cardiometabolic Health in Latino Individuals Living in the United States
CONCLUSIONS: IEA strongly patterns cardiometabolic health among Hispanic/Latino individuals living in the United States, suggesting that promotion of higher education is associated with reductions in obesity and MetS, potentially benefitting future generations of this population.PMID:34096684 | DOI:10.1002/oby.23156 (Source: Obesity)
Source: Obesity - June 7, 2021 Category: Eating Disorders & Weight Management Authors: Emma G Crenshaw Lindsay Fern ández-Rhodes Chantel L Martin Penny Gordon-Larsen Mary N Haan Allison E Aiello Source Type: research

Intergenerational Educational Attainment and Cardiometabolic Health in Latino Individuals Living in the United States
CONCLUSIONS: IEA strongly patterns cardiometabolic health among Hispanic/Latino individuals living in the United States, suggesting that promotion of higher education is associated with reductions in obesity and MetS, potentially benefitting future generations of this population.PMID:34096684 | DOI:10.1002/oby.23156 (Source: Obesity)
Source: Obesity - June 7, 2021 Category: Eating Disorders & Weight Management Authors: Emma G Crenshaw Lindsay Fern ández-Rhodes Chantel L Martin Penny Gordon-Larsen Mary N Haan Allison E Aiello Source Type: research

Cardiovascular Disease Risk Factors by BMI and Age in United States Firefighters
CONCLUSIONS: An increasing prevalence of risk factors with older age and higher BMI suggests that preventive strategies should be initiated in younger firefighters and aggressively promoted or mandated throughout firefighters' careers.PMID:34060241 | DOI:10.1002/oby.23175 (Source: Obesity)
Source: Obesity - June 1, 2021 Category: Eating Disorders & Weight Management Authors: Emilie D Bode Kevin C Mathias Donald F Stewart Steven M Moffatt Kepra Jack Denise L Smith Source Type: research

Cardiovascular Disease Risk Factors by BMI and Age in United States Firefighters
CONCLUSIONS: An increasing prevalence of risk factors with older age and higher BMI suggests that preventive strategies should be initiated in younger firefighters and aggressively promoted or mandated throughout firefighters' careers.PMID:34060241 | DOI:10.1002/oby.23175 (Source: Obesity)
Source: Obesity - June 1, 2021 Category: Eating Disorders & Weight Management Authors: Emilie D Bode Kevin C Mathias Donald F Stewart Steven M Moffatt Kepra Jack Denise L Smith Source Type: research

Cardiovascular Disease Risk Factors by BMI and Age in United States Firefighters
CONCLUSIONS: An increasing prevalence of risk factors with older age and higher BMI suggests that preventive strategies should be initiated in younger firefighters and aggressively promoted or mandated throughout firefighters' careers.PMID:34060241 | DOI:10.1002/oby.23175 (Source: Obesity)
Source: Obesity - June 1, 2021 Category: Eating Disorders & Weight Management Authors: Emilie D Bode Kevin C Mathias Donald F Stewart Steven M Moffatt Kepra Jack Denise L Smith Source Type: research

Cardiovascular Disease Risk Factors by BMI and Age in United States Firefighters
CONCLUSIONS: An increasing prevalence of risk factors with older age and higher BMI suggests that preventive strategies should be initiated in younger firefighters and aggressively promoted or mandated throughout firefighters' careers.PMID:34060241 | DOI:10.1002/oby.23175 (Source: Obesity)
Source: Obesity - June 1, 2021 Category: Eating Disorders & Weight Management Authors: Emilie D Bode Kevin C Mathias Donald F Stewart Steven M Moffatt Kepra Jack Denise L Smith Source Type: research

Cardiovascular Disease Risk Factors by BMI and Age in United States Firefighters
CONCLUSIONS: An increasing prevalence of risk factors with older age and higher BMI suggests that preventive strategies should be initiated in younger firefighters and aggressively promoted or mandated throughout firefighters' careers.PMID:34060241 | DOI:10.1002/oby.23175 (Source: Obesity)
Source: Obesity - June 1, 2021 Category: Eating Disorders & Weight Management Authors: Emilie D Bode Kevin C Mathias Donald F Stewart Steven M Moffatt Kepra Jack Denise L Smith Source Type: research

Liver Fat Reduction After Gastric Banding and Associations with Changes in Insulin Sensitivity and β-Cell Function
CONCLUSIONS: Reduction in LFC after gastric banding surgery appears to be an important factor associated with long-term improvements in insulin sensitivity and glycemic profiles in adults with obesity and prediabetes or early type 2 diabetes.PMID:34038037 | DOI:10.1002/oby.23174 (Source: Obesity)
Source: Obesity - May 26, 2021 Category: Eating Disorders & Weight Management Authors: Anny H Xiang Mayra P Martinez Enrique Trigo Kristina M Utzschneider Melanie Cree-Green Silva A Arslanian David A Ehrmann Sonia Caprio Passant H I H Mohamed Darryl H Hwang Namir Katkhouda Krishna S Nayak Thomas A Buchanan RISE Consortium Source Type: research

Liver Fat Reduction After Gastric Banding and Associations with Changes in Insulin Sensitivity and β-Cell Function
CONCLUSIONS: Reduction in LFC after gastric banding surgery appears to be an important factor associated with long-term improvements in insulin sensitivity and glycemic profiles in adults with obesity and prediabetes or early type 2 diabetes.PMID:34038037 | DOI:10.1002/oby.23174 (Source: Obesity)
Source: Obesity - May 26, 2021 Category: Eating Disorders & Weight Management Authors: Anny H Xiang Mayra P Martinez Enrique Trigo Kristina M Utzschneider Melanie Cree-Green Silva A Arslanian David A Ehrmann Sonia Caprio Passant H I H Mohamed Darryl H Hwang Namir Katkhouda Krishna S Nayak Thomas A Buchanan RISE Consortium Source Type: research

Liver Fat Reduction After Gastric Banding and Associations with Changes in Insulin Sensitivity and β-Cell Function
CONCLUSIONS: Reduction in LFC after gastric banding surgery appears to be an important factor associated with long-term improvements in insulin sensitivity and glycemic profiles in adults with obesity and prediabetes or early type 2 diabetes.PMID:34038037 | DOI:10.1002/oby.23174 (Source: Obesity)
Source: Obesity - May 26, 2021 Category: Eating Disorders & Weight Management Authors: Anny H Xiang Mayra P Martinez Enrique Trigo Kristina M Utzschneider Melanie Cree-Green Silva A Arslanian David A Ehrmann Sonia Caprio Passant H I H Mohamed Darryl H Hwang Namir Katkhouda Krishna S Nayak Thomas A Buchanan RISE Consortium Source Type: research

Liver Fat Reduction After Gastric Banding and Associations with Changes in Insulin Sensitivity and β-Cell Function
CONCLUSIONS: Reduction in LFC after gastric banding surgery appears to be an important factor associated with long-term improvements in insulin sensitivity and glycemic profiles in adults with obesity and prediabetes or early type 2 diabetes.PMID:34038037 | DOI:10.1002/oby.23174 (Source: Obesity)
Source: Obesity - May 26, 2021 Category: Eating Disorders & Weight Management Authors: Anny H Xiang Mayra P Martinez Enrique Trigo Kristina M Utzschneider Melanie Cree-Green Silva A Arslanian David A Ehrmann Sonia Caprio Passant H I H Mohamed Darryl H Hwang Namir Katkhouda Krishna S Nayak Thomas A Buchanan RISE Consortium Source Type: research

Liver Fat Reduction After Gastric Banding and Associations with Changes in Insulin Sensitivity and β-Cell Function
CONCLUSIONS: Reduction in LFC after gastric banding surgery appears to be an important factor associated with long-term improvements in insulin sensitivity and glycemic profiles in adults with obesity and prediabetes or early type 2 diabetes.PMID:34038037 | DOI:10.1002/oby.23174 (Source: Obesity)
Source: Obesity - May 26, 2021 Category: Eating Disorders & Weight Management Authors: Anny H Xiang Mayra P Martinez Enrique Trigo Kristina M Utzschneider Melanie Cree-Green Silva A Arslanian David A Ehrmann Sonia Caprio Passant H I H Mohamed Darryl H Hwang Namir Katkhouda Krishna S Nayak Thomas A Buchanan RISE Consortium Source Type: research

Epicardial fat inflammation response to COVID-19 therapies
Obesity (Silver Spring). 2021 May 24. doi: 10.1002/oby.23232. Online ahead of print.ABSTRACTOBJECTIVE: Adipose tissue plays a role in the novel coronavirus disease 2019 (COVID-19). Epicardial adipose tissue (EAT), a unique visceral fat, presents with high degree of inflammation in severe COVID-19 disease. Whether and how adipose tissue may respond to the COVID-19 therapies is unknown.METHODS: We retrospectively analyzed the difference in computed tomography (CT) measured EAT and subcutaneous (SAT) attenuation, defined as mean attenuation expressed in Hounsfield units (HU), in 72 patients [mean±SD age was 59.6±...
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Gianluca Iacobellis Alexis Elias Malavazos Sara Basilico Silvia Tresoldi Rocco Francesco Rinaldo Carola Dubini Gloria Capitanio Francesca Serpi Simone Schiaffino Omar Alessandro Oliva Maurizio Cariati Lelio Morricone Stefano Centanni Francesco Sardanelli Source Type: research

Sitting Time, Type, and Context Among Long-Term Weight-Loss Maintainers
CONCLUSIONS: Weight-loss maintainers reported less time sitting than weight-stable individuals with obesity. Future research should test the efficacy of targeting sitting time to help promote long-term weight-loss maintenance.PMID:34029443 | DOI:10.1002/oby.23148 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: James Roake Suzanne Phelan Noemi Alarcon Sarah K Keadle Chad D Rethorst Gary D Foster Source Type: research

Eating and Exercise-Related Correlates of Weight Stigma: A Multinational Investigation
CONCLUSIONS: Study findings document uniform health-related correlates of weight stigma within a multinational context and underscore the need for global initiatives to curtail weight stigma in order to support population health.PMID:34029444 | DOI:10.1002/oby.23168 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Leah M Lessard Rebecca M Puhl Mary S Himmelstein Rebecca L Pearl Gary D Foster Source Type: research

The Triple Health Threat of Diabetes, Obesity, and Cancer-Epidemiology, Disparities, Mechanisms, and Interventions
This report provides an overview of the symposium and describes key research gaps and pressing questions in need of answers to advance the field. The collective burden of obesity, diabetes, and cancer represents one of the largest public health challenges of the century. Although the symposium was titled "hitting a triple," it was recognized that being able to disrupt the linkages among obesity, diabetes, and cancer would be a "grand slam" for public health and medicine.PMID:34029445 | DOI:10.1002/oby.23161 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Justin C Brown Tiffany L Carson Henry J Thompson Tanya Agurs-Collins Source Type: research

Metabolomic Profiles of Shift Workers and Day Workers: A Cross-Sectional Study
Obesity (Silver Spring). 2021 Jun;29(6):1074-1082. doi: 10.1002/oby.23164.ABSTRACTOBJECTIVE: The purpose of this study was to characterize the metabolomic profiles of shift workers and day workers and to discover the effect of shift work on workers' metabolic health.METHODS: A total of 824 participants aged 25 to 55 years were recruited, and 485 (275 shift workers and 210 day workers) completed the study. The mean age of the shift workers was 37.32 (5.53) years old, and that of day workers was 36.50 (7.83) years old. Serum and salivary samples were collected for the detection of key biochemical indicators (melatonin, chole...
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Xinru Huang Xiaoyi Chen Shiyu Zhao Jiaojiao Hou Li Huang Jie Xu Wei Wang Mengting He Ouxi Shen Jie Zhang Source Type: research

Obesity and Cancer Risk in White and Black Adults: A Prospective Cohort Study
CONCLUSIONS: In this diverse cohort of adults, participant race and sex modified the prognostic associations of anthropometric measures of obesity and cancer risk.PMID:34029447 | DOI:10.1002/oby.23163 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Justin C Brown Shengping Yang Emily F Mire Xiaocheng Wu Lucio Miele Augusto Ochoa Jovanny Zabaleta Peter T Katzmarzyk Source Type: research

Prolonged Glucagon Infusion Does Not Affect Energy Expenditure in Individuals with Overweight/Obesity: A Randomized Trial
Obesity (Silver Spring). 2021 Jun;29(6):1003-1013. doi: 10.1002/oby.23141.ABSTRACTOBJECTIVE: The aim of this study was to determine the effects of prolonged (72 hours) glucagon administration at a low dose (LD) (12.5 ng/kg/min) and high dose (HD) (25 ng/kg/min) on energy expenditure (EE) in healthy individuals with overweight or obesity.METHODS: Thirty-one healthy participants with overweight or obesity (BMI of 27-45 kg/m2 , 26-55 years old, 23 females) were randomized into LD, HD, or placebo groups and underwent 72-hour intravenous infusion of glucagon. Whole-room calorimetry was used to assess EE and substrate use during...
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Katie L Whytock Elvis A Carnero Rick B Vega Joachim Tillner Christopher Bock Karthik Chivukula Fanchao Yi Christian Meyer Steven R Smith Lauren M Sparks Source Type: research

Neonatal and Adolescent Adipocytokines as Predictors of Adiposity and Cardiometabolic Risk in Adolescence
CONCLUSIONS: In this cohort, changes in leptin concentrations and adiponectin/leptin ratios over childhood were associated with adiposity and cardiometabolic risk scores, indicating that adipocytokine concentrations are potential biomarkers for predicting excess adiposity and cardiometabolic risk in adolescence.PMID:34029449 | DOI:10.1002/oby.23160 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Catherine O Buck Nan Li Charles B Eaton Karl T Kelsey Kim M Cecil Heidi J Kalkwarf Kimberly Yolton Bruce P Lanphear Aimin Chen Joseph M Braun Source Type: research

Epicardial fat inflammation response to COVID-19 therapies
Obesity (Silver Spring). 2021 May 24. doi: 10.1002/oby.23232. Online ahead of print.ABSTRACTOBJECTIVE: Adipose tissue plays a role in the novel coronavirus disease 2019 (COVID-19). Epicardial adipose tissue (EAT), a unique visceral fat, presents with high degree of inflammation in severe COVID-19 disease. Whether and how adipose tissue may respond to the COVID-19 therapies is unknown.METHODS: We retrospectively analyzed the difference in computed tomography (CT) measured EAT and subcutaneous (SAT) attenuation, defined as mean attenuation expressed in Hounsfield units (HU), in 72 patients [mean±SD age was 59.6±...
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Gianluca Iacobellis Alexis Elias Malavazos Sara Basilico Silvia Tresoldi Rocco Francesco Rinaldo Carola Dubini Gloria Capitanio Francesca Serpi Simone Schiaffino Omar Alessandro Oliva Maurizio Cariati Lelio Morricone Stefano Centanni Francesco Sardanelli Source Type: research

Sitting Time, Type, and Context Among Long-Term Weight-Loss Maintainers
CONCLUSIONS: Weight-loss maintainers reported less time sitting than weight-stable individuals with obesity. Future research should test the efficacy of targeting sitting time to help promote long-term weight-loss maintenance.PMID:34029443 | DOI:10.1002/oby.23148 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: James Roake Suzanne Phelan Noemi Alarcon Sarah K Keadle Chad D Rethorst Gary D Foster Source Type: research

Eating and Exercise-Related Correlates of Weight Stigma: A Multinational Investigation
CONCLUSIONS: Study findings document uniform health-related correlates of weight stigma within a multinational context and underscore the need for global initiatives to curtail weight stigma in order to support population health.PMID:34029444 | DOI:10.1002/oby.23168 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Leah M Lessard Rebecca M Puhl Mary S Himmelstein Rebecca L Pearl Gary D Foster Source Type: research

The Triple Health Threat of Diabetes, Obesity, and Cancer-Epidemiology, Disparities, Mechanisms, and Interventions
This report provides an overview of the symposium and describes key research gaps and pressing questions in need of answers to advance the field. The collective burden of obesity, diabetes, and cancer represents one of the largest public health challenges of the century. Although the symposium was titled "hitting a triple," it was recognized that being able to disrupt the linkages among obesity, diabetes, and cancer would be a "grand slam" for public health and medicine.PMID:34029445 | DOI:10.1002/oby.23161 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Justin C Brown Tiffany L Carson Henry J Thompson Tanya Agurs-Collins Source Type: research

Metabolomic Profiles of Shift Workers and Day Workers: A Cross-Sectional Study
Obesity (Silver Spring). 2021 Jun;29(6):1074-1082. doi: 10.1002/oby.23164.ABSTRACTOBJECTIVE: The purpose of this study was to characterize the metabolomic profiles of shift workers and day workers and to discover the effect of shift work on workers' metabolic health.METHODS: A total of 824 participants aged 25 to 55 years were recruited, and 485 (275 shift workers and 210 day workers) completed the study. The mean age of the shift workers was 37.32 (5.53) years old, and that of day workers was 36.50 (7.83) years old. Serum and salivary samples were collected for the detection of key biochemical indicators (melatonin, chole...
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Xinru Huang Xiaoyi Chen Shiyu Zhao Jiaojiao Hou Li Huang Jie Xu Wei Wang Mengting He Ouxi Shen Jie Zhang Source Type: research

Obesity and Cancer Risk in White and Black Adults: A Prospective Cohort Study
CONCLUSIONS: In this diverse cohort of adults, participant race and sex modified the prognostic associations of anthropometric measures of obesity and cancer risk.PMID:34029447 | DOI:10.1002/oby.23163 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Justin C Brown Shengping Yang Emily F Mire Xiaocheng Wu Lucio Miele Augusto Ochoa Jovanny Zabaleta Peter T Katzmarzyk Source Type: research

Prolonged Glucagon Infusion Does Not Affect Energy Expenditure in Individuals with Overweight/Obesity: A Randomized Trial
Obesity (Silver Spring). 2021 Jun;29(6):1003-1013. doi: 10.1002/oby.23141.ABSTRACTOBJECTIVE: The aim of this study was to determine the effects of prolonged (72 hours) glucagon administration at a low dose (LD) (12.5 ng/kg/min) and high dose (HD) (25 ng/kg/min) on energy expenditure (EE) in healthy individuals with overweight or obesity.METHODS: Thirty-one healthy participants with overweight or obesity (BMI of 27-45 kg/m2 , 26-55 years old, 23 females) were randomized into LD, HD, or placebo groups and underwent 72-hour intravenous infusion of glucagon. Whole-room calorimetry was used to assess EE and substrate use during...
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Katie L Whytock Elvis A Carnero Rick B Vega Joachim Tillner Christopher Bock Karthik Chivukula Fanchao Yi Christian Meyer Steven R Smith Lauren M Sparks Source Type: research

Neonatal and Adolescent Adipocytokines as Predictors of Adiposity and Cardiometabolic Risk in Adolescence
CONCLUSIONS: In this cohort, changes in leptin concentrations and adiponectin/leptin ratios over childhood were associated with adiposity and cardiometabolic risk scores, indicating that adipocytokine concentrations are potential biomarkers for predicting excess adiposity and cardiometabolic risk in adolescence.PMID:34029449 | DOI:10.1002/oby.23160 (Source: Obesity)
Source: Obesity - May 24, 2021 Category: Eating Disorders & Weight Management Authors: Catherine O Buck Nan Li Charles B Eaton Karl T Kelsey Kim M Cecil Heidi J Kalkwarf Kimberly Yolton Bruce P Lanphear Aimin Chen Joseph M Braun Source Type: research

Mid-Arm Muscle and Subcutaneous Fat Associated with All-Cause Mortality Independent of BMI: A Prospective Cohort Study
CONCLUSIONS: Mid-arm muscle and subcutaneous fat were inversely associated with all-cause mortality, independent of BMI, beyond the elderly population. Mid-arm muscle and subcutaneous fat made comparable contributions to and had positive joint effects on all-cause mortality.PMID:34021531 | DOI:10.1002/oby.23179 (Source: Obesity)
Source: Obesity - May 22, 2021 Category: Eating Disorders & Weight Management Authors: Liyun He Na Yang Jialu Wang Jingyue Huang Wei Li Lingling Xu Fan Ping Yuxiu Li Huabing Zhang Source Type: research

Mid-Arm Muscle and Subcutaneous Fat Associated with All-Cause Mortality Independent of BMI: A Prospective Cohort Study
CONCLUSIONS: Mid-arm muscle and subcutaneous fat were inversely associated with all-cause mortality, independent of BMI, beyond the elderly population. Mid-arm muscle and subcutaneous fat made comparable contributions to and had positive joint effects on all-cause mortality.PMID:34021531 | DOI:10.1002/oby.23179 (Source: Obesity)
Source: Obesity - May 22, 2021 Category: Eating Disorders & Weight Management Authors: Liyun He Na Yang Jialu Wang Jingyue Huang Wei Li Lingling Xu Fan Ping Yuxiu Li Huabing Zhang Source Type: research

Mid-Arm Muscle and Subcutaneous Fat Associated with All-Cause Mortality Independent of BMI: A Prospective Cohort Study
CONCLUSIONS: Mid-arm muscle and subcutaneous fat were inversely associated with all-cause mortality, independent of BMI, beyond the elderly population. Mid-arm muscle and subcutaneous fat made comparable contributions to and had positive joint effects on all-cause mortality.PMID:34021531 | DOI:10.1002/oby.23179 (Source: Obesity)
Source: Obesity - May 22, 2021 Category: Eating Disorders & Weight Management Authors: Liyun He Na Yang Jialu Wang Jingyue Huang Wei Li Lingling Xu Fan Ping Yuxiu Li Huabing Zhang Source Type: research

Impact of the COVID-19 pandemic on initial weight loss in a digital weight management program: A natural experiment
CONCLUSIONS: Over a 30-week enrollment period, COVID-19 had negative effects on both weight loss and food self-monitoring, but the effects were short-lived. Those participating in evidence-based weight management programs can expect similar levels of initial weight loss as those experienced pre-pandemic.PMID:34009723 | DOI:10.1002/oby.23233 (Source: Obesity)
Source: Obesity - May 19, 2021 Category: Eating Disorders & Weight Management Authors: Tiffany Bullard Adam Medcalf Chad Rethorst Gary D Foster Source Type: research

Impact of the COVID-19 pandemic on initial weight loss in a digital weight management program: A natural experiment
CONCLUSIONS: Over a 30-week enrollment period, COVID-19 had negative effects on both weight loss and food self-monitoring, but the effects were short-lived. Those participating in evidence-based weight management programs can expect similar levels of initial weight loss as those experienced pre-pandemic.PMID:34009723 | DOI:10.1002/oby.23233 (Source: Obesity)
Source: Obesity - May 19, 2021 Category: Eating Disorders & Weight Management Authors: Tiffany Bullard Adam Medcalf Chad Rethorst Gary D Foster Source Type: research

Impact of the COVID-19 pandemic on initial weight loss in a digital weight management program: A natural experiment
CONCLUSIONS: Over a 30-week enrollment period, COVID-19 had negative effects on both weight loss and food self-monitoring, but the effects were short-lived. Those participating in evidence-based weight management programs can expect similar levels of initial weight loss as those experienced pre-pandemic.PMID:34009723 | DOI:10.1002/oby.23233 (Source: Obesity)
Source: Obesity - May 19, 2021 Category: Eating Disorders & Weight Management Authors: Tiffany Bullard Adam Medcalf Chad Rethorst Gary D Foster Source Type: research

Human Brown Adipose Tissue-A Decade Later
Obesity (Silver Spring). 2021 May 17. doi: 10.1002/oby.23166. Online ahead of print.NO ABSTRACTPMID:34002540 | DOI:10.1002/oby.23166 (Source: Obesity)
Source: Obesity - May 18, 2021 Category: Eating Disorders & Weight Management Authors: Wouter D van Marken Lichtenbelt Source Type: research

Impact of Energy Turnover on the Regulation of Energy and Macronutrient Balance
Obesity (Silver Spring). 2021 May 17. doi: 10.1002/oby.23133. Online ahead of print.ABSTRACTEnergy turnover, defined as the average daily total metabolic rate, can be normalized for basal metabolic rate in order to compare physical activity level between individuals, whereas normalization of energy turnover for energy intake (energy flux) allows investigation of its impact on regulation of energy partitioning independent of energy balance. Appetite sensations better correspond to energy requirements at a high compared with a low energy turnover. Adaptation of energy intake to habitual energy turnover may, however, contribu...
Source: Obesity - May 18, 2021 Category: Eating Disorders & Weight Management Authors: Anja Bosy-Westphal Franziska A H ägele Manfred J M üller Source Type: research

Human Brown Adipose Tissue-A Decade Later
Obesity (Silver Spring). 2021 May 17. doi: 10.1002/oby.23166. Online ahead of print.NO ABSTRACTPMID:34002540 | DOI:10.1002/oby.23166 (Source: Obesity)
Source: Obesity - May 18, 2021 Category: Eating Disorders & Weight Management Authors: Wouter D van Marken Lichtenbelt Source Type: research

Impact of Energy Turnover on the Regulation of Energy and Macronutrient Balance
Obesity (Silver Spring). 2021 May 17. doi: 10.1002/oby.23133. Online ahead of print.ABSTRACTEnergy turnover, defined as the average daily total metabolic rate, can be normalized for basal metabolic rate in order to compare physical activity level between individuals, whereas normalization of energy turnover for energy intake (energy flux) allows investigation of its impact on regulation of energy partitioning independent of energy balance. Appetite sensations better correspond to energy requirements at a high compared with a low energy turnover. Adaptation of energy intake to habitual energy turnover may, however, contribu...
Source: Obesity - May 18, 2021 Category: Eating Disorders & Weight Management Authors: Anja Bosy-Westphal Franziska A H ägele Manfred J M üller Source Type: research

Association of Visceral Adipose Tissue and Insulin Resistance with Incident Metabolic Syndrome Independent of Obesity Status: The IRAS Family Study
CONCLUSIONS: Differing levels of VAT may be driving metabolic heterogeneity within BMI categories. Both overall and abdominal obesity (VAT) may play a role in the development of MetS. Increased VAT over time contributed additional risk.PMID:33998167 | DOI:10.1002/oby.23177 (Source: Obesity)
Source: Obesity - May 17, 2021 Category: Eating Disorders & Weight Management Authors: Morgana Mongraw-Chaffin Kristen G Hairston Anthony J G Hanley Janet A Tooze Jill M Norris Nicolette D Palmer Donald W Bowden Carlos Lorenzo Yii-Der Ida Chen Lynne E Wagenknecht Source Type: research

What Links Maternal Prepregnancy BMI to Early Childhood BMI: A Serial Mediation Analysis
CONCLUSIONS: Maternal GWG, infant birth weight, and the first-6-month ΔWAZ mediated the effects of maternal ppBMI on children's BMI. Interventions targeting these factors can mitigate the risk of childhood obesity.PMID:33991063 | DOI:10.1002/oby.23176 (Source: Obesity)
Source: Obesity - May 15, 2021 Category: Eating Disorders & Weight Management Authors: Yuanyuan Zhang Hong Mei Ke Xu Chunan Li Zhiguo Xia Yafei Tan Shaoping Yang Jianduan Zhang Source Type: research

What Links Maternal Prepregnancy BMI to Early Childhood BMI: A Serial Mediation Analysis
CONCLUSIONS: Maternal GWG, infant birth weight, and the first-6-month ΔWAZ mediated the effects of maternal ppBMI on children's BMI. Interventions targeting these factors can mitigate the risk of childhood obesity.PMID:33991063 | DOI:10.1002/oby.23176 (Source: Obesity)
Source: Obesity - May 15, 2021 Category: Eating Disorders & Weight Management Authors: Yuanyuan Zhang Hong Mei Ke Xu Chunan Li Zhiguo Xia Yafei Tan Shaoping Yang Jianduan Zhang Source Type: research

What Links Maternal Prepregnancy BMI to Early Childhood BMI: A Serial Mediation Analysis
CONCLUSIONS: Maternal GWG, infant birth weight, and the first-6-month ΔWAZ mediated the effects of maternal ppBMI on children's BMI. Interventions targeting these factors can mitigate the risk of childhood obesity.PMID:33991063 | DOI:10.1002/oby.23176 (Source: Obesity)
Source: Obesity - May 15, 2021 Category: Eating Disorders & Weight Management Authors: Yuanyuan Zhang Hong Mei Ke Xu Chunan Li Zhiguo Xia Yafei Tan Shaoping Yang Jianduan Zhang Source Type: research

Does Lifestyle Intervention Improve Health of Adults with Overweight/Obesity and Type 2 Diabetes: Findings from the Look AHEAD Randomized Trial
Obesity (Silver Spring). 2021 May 14. doi: 10.1002/oby.23158. Online ahead of print.ABSTRACTThis paper reviews the main findings from the Action for Health in Diabetes (Look AHEAD) Trial, a randomized trial testing the long-term health effects of intensive lifestyle interventions (ILIs) in 5,145 persons with overweight/obesity and type 2 diabetes. Although the primary outcome originally focused on cardiovascular morbidity and mortality, secondary outcomes included a broad range of health parameters related to diabetes and obesity. As the cohort aged, study outcomes were expanded to include health problems affecting geriatr...
Source: Obesity - May 14, 2021 Category: Eating Disorders & Weight Management Authors: Rena R Wing Look AHEAD Research Group Source Type: research

BMI and pneumonia outcomes in critically ill COVID-19 patients: an international multicenter study
CONCLUSION: In critically ill COVID-19 patients, we observed a linear association between BMI and the need for IMV, independent of other metabolic risk factors, and a non-linear association between BMI and mortality risk. (NCT04391738).PMID:33966355 | DOI:10.1002/oby.23223 (Source: Obesity)
Source: Obesity - May 9, 2021 Category: Eating Disorders & Weight Management Authors: Mikael Chetboun Violeta Raverdy Julien Labreuche Arthur Simonnet Florent Wallet Cyrielle Caussy Massimo Antonelli Antonio Artigas Gemma Goma Ferhat Meziani Julie Helms Eleftherios Mylonakis Mitchell M Levy Markos Kalligeros Nicola Latronico Simone Piva Ch Source Type: research

BMI and pneumonia outcomes in critically ill COVID-19 patients: an international multicenter study
CONCLUSION: In critically ill COVID-19 patients, we observed a linear association between BMI and the need for IMV, independent of other metabolic risk factors, and a non-linear association between BMI and mortality risk. (NCT04391738).PMID:33966355 | DOI:10.1002/oby.23223 (Source: Obesity)
Source: Obesity - May 9, 2021 Category: Eating Disorders & Weight Management Authors: Mikael Chetboun Violeta Raverdy Julien Labreuche Arthur Simonnet Florent Wallet Cyrielle Caussy Massimo Antonelli Antonio Artigas Gemma Goma Ferhat Meziani Julie Helms Eleftherios Mylonakis Mitchell M Levy Markos Kalligeros Nicola Latronico Simone Piva Ch Source Type: research