Ochratoxin A and related fungi in Brazilian black pepper (Piper nigrum L.)
Publication date: Available online 10 February 2021Source: Food Research InternationalAuthor(s): Adriana Raquel Persson da Silva, Maria Helena Pelegrinelli Fungaro, Josué José Silva, Ligia Manoel Martins, Marta Hiromi Taniwaki, Beatriz Thie Iamanaka (Source: Food Research International)
Source: Food Research International - February 10, 2021 Category: Food Science Source Type: research
Molecules, Vol. 26, Pages 934: Selective Cytotoxicity of Piperine Over Multidrug Resistance Leukemic Cells
ian M. Rumjanek
Multidrug resistance (MDR) is the main challenge in the treatment of chronic myeloid leukemia (CML), and P-glycoprotein (P-gp) overexpression is an important mechanism involved in this resistance process. However, some compounds can selectively affect MDR cells, inducing collateral sensitivity (CS), which may be dependent on P-gp. The aim of this study was to investigate the effect of piperine, a phytochemical from black pepper, on CS induction in CML MDR cells, and the mechanisms involved. The results indicate that piperine induced CS, being more cytotoxic to K562-derived MDR cells (Lucena-1 and FEPS) ...
Source: Molecules - February 10, 2021 Category: Chemistry Authors: Julia Quarti Daianne N. M. Torres Erika Ferreira Raphael S. Vidal Fabiana Casanova Luciana B. Chiarini Eliane Fialho Vivian M. Rumjanek Tags: Article Source Type: research
Molecules, Vol. 26, Pages 732: Combining Normal/Reversed-Phase HPTLC with Univariate Calibration for the Piperine Quantification with Traditional and Ultrasound-Assisted Extracts of Various Food Spices of Piper nigrum L. under Green Analytical Chemistry Viewpoint
z Shakeel
Due to unavailability of sustainable analytical techniques for the quantitation of piperine (PPN) in food and pharmaceutical samples, there was a need to develop a rapid and sensitive sustainable analytical technique for the quantitation of PPN. Therefore, the current research presents a fast and highly sensitive normal/reversed-phase high-performance thin-layer chromatography (HPTLC) technique with classical univariate calibration for the quantitation of PPN in various food spices of black pepper with traditional (TE) and ultrasound-assisted extracts (UBE) of various food spices of Piper nigrum L. under gree...
Source: Molecules - January 31, 2021 Category: Chemistry Authors: Mohammed H. Alqarni Prawez Alam Ahmed I. Foudah Magdy M. Muharram Faiyaz Shakeel Tags: Article Source Type: research
Efficacy of the Co-Administration of Piper Nigrum and Partially Purified Product from Abroma Augusta in Metabolic Syndrome
Abstract (Source: Metabolism - Clinical and Experimental)
Source: Metabolism - Clinical and Experimental - January 29, 2021 Category: Biomedical Science Authors: Maliha Sarfraz Tags: 0144 Source Type: research
Cross infection and molecular characterization of Colletotrichum spp. infecting coffee and black pepper
Publication date: Available online 4 January 2021Source: Physiological and Molecular Plant PathologyAuthor(s): Santoshreddy Machenahalli, Pavankumar Jingade, Ranjini A. P, Madhu S. Giri, Arun Kumar C. Huded, Sudha M, Daivasikamani S, Manoj Kumar Mishra (Source: Physiological and Molecular Plant Pathology)
Source: Physiological and Molecular Plant Pathology - January 6, 2021 Category: Molecular Biology Source Type: research
In vitro α-amylase and α-glucosidase enzyme inhibition and antioxidant activity by capsaicin and piperine from Capsicum chinense and Piper nigrum fruits.
Abstract
In the present study, α-amylase and α-glucosidase inhibitory effect and antioxidant activity of capsaicin and piperine from the ethanolic extract of Capsicum chinense (EECch) and Piper nigrum (EEPn) fruits were investigated. Results revealed that EECch exhibited the highest phenolic (154 mg GAE/100 g of tissue) and flavonoid content (75 mg RtE/100 g of tissue) in comparison with EEPn. The predominant compound detected in EECch and EEPn by GC-EIMS analysis was the capsaicin and piperine, respectively. The capsaicin and piperine showed the highest α-amylase and α-glucosidase inhibitory e...
Source: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes - January 4, 2021 Category: Environmental Health Authors: Magaña-Barajas E, Buitimea-Cantúa GV, Hernández-Morales A, Torres-Pelayo VDR, Vázquez-Martínez J, Buitimea-Cantúa NE Tags: J Environ Sci Health B Source Type: research
Antioxidant, hepatoprotective and antifungal activities of black pepper (Piper nigrum L.) essential oil
Publication date: 1 June 2021Source: Food Chemistry, Volume 346Author(s): Chi Zhang, Jiechang Zhao, Erhunmwunsee Famous, Shenyuan Pan, Xue Peng, Jun Tian (Source: Food Chemistry)
Source: Food Chemistry - January 1, 2021 Category: Food Science Source Type: research
Therapeutic Approach Against 2019-nCoV by Inhibition of the ACE-2 receptor
Drug Res (Stuttg) DOI: 10.1055/a-1337-4462The continued spread of the 2019 novel coronavirus (2019-nCoV) has prompted
global concern. The formal name given to 2019-nCoV by the World Health
Organization is COVID-19, while the International Committee on Taxonomy has
named it severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Due
to this viral attack, nations around the world have issued lockdown
restrictions. Presently, there is no effective way to control the spread of
2019-nCoV, except through social distancing and hygienic activities.
World-class scientists and researchers are trying to develop vaccines and
med...
Source: Drug Research - December 23, 2020 Category: Drugs & Pharmacology Authors: Kumar, Gajendra Kumar, Dharmendra Singh, Netra Pal Tags: Original Article Source Type: research
Near-infrared spectroscopy in quality control of Piper nigrum: A comparison of performance of benchtop and handheld spectrometers.
Abstract
Developing effective ways for controlling the quality of natural products that are sold in high volume worldwide is currently one of the most urgent goals of analytical chemistry. Black pepper (Piper nigrum) is a major spice that constitutes 34% of the global spice market. Black pepper is highly prone to quality variations, arising from alteration of the piperine content. Miniaturized NIR spectroscopy offers a high-throughput, cost-effective and laboratory independent technique for quality control of black pepper. Handheld NIR spectrometers differ in the implemented technology, with impact on thei...
Source: Talanta - December 12, 2020 Category: Chemistry Authors: Mayr S, Beć KB, Grabska J, Schneckenreiter E, Huck CW Tags: Talanta Source Type: research
Drought responsiveness in black pepper (Piper nigrum L.): genes associated and development of a web-genomic resource.
This article is protected by copyright. All rights reserved.
PMID: 33305409 [PubMed - as supplied by publisher] (Source: Physiological Research)
Source: Physiological Research - December 10, 2020 Category: Physiology Authors: Negi A, Johnson George K, Jasrotia RS, Madhavan S, Jaiswal S, Angadi UB, Iquebal MA, Manju KP, Umadevi P, Rai A, Kumar D Tags: Physiol Plant Source Type: research
Cardiovascular protective effect of black pepper (Piper nigrum L.) and its major bioactive constituent piperine
Publication date: Available online 4 December 2020Source: Trends in Food Science & TechnologyAuthor(s): Dongdong Wang, Lu Zhang, Jiansheng Huang, K. Himabindu, Devesh Tewari, Jarosław O. Horbańczuk, Suowen Xu, Zhu Chen, Atanas G. Atanasov (Source: Trends in Food Science and Technology)
Source: Trends in Food Science and Technology - December 4, 2020 Category: Food Science Source Type: research
Re-exploring an Epicentre Spice with Immense Therapeutic Potentials: Black Pepper (Piper nigrum)
Conclusion: The overall review suggests that P. nigrum is not just a commonly utilized spice but also at the same time utilized as a traditional plant with immense therapeutic potentials. The review also suggests that limited work has been reported on the neuropharmacological activity of P. nigrum. So, scientific evaluation of its neuroprotective effect can be a thrust area for the research. (Source: Current Nutrition and Food Science)
Source: Current Nutrition and Food Science - November 29, 2020 Category: Nutrition Source Type: research
Alginate hydrogels: Sustained release system to analyze the effect of traditional excipients on curcumin availability.
Abstract
Curcumin, a molecule of immense pharmacological significance is also known to exhibit poor aqueous solubility and low bioavailability. Different strategies have been adopted to enhance the aqueous solubility of curcumin, but report on the effect of traditional excipients on curcumin solubility still stand in need of. Here, we presented the significance of different traditional excipients used in anti-inflammatory formulations on curcumin solubility. The endeavor has been undertaken with the hypothesis that "traditional formulation used since ages have a scientific basis". To meet the quest we enca...
Source: Bioorganic Chemistry - November 24, 2020 Category: Chemistry Authors: Mor N, Raghav N Tags: Bioorg Chem Source Type: research
A Review of Malaysian Herbal Plants and Their Active Constituents with Potential Therapeutic Applications in Sepsis.
Authors: Liew KY, Hafiz MF, Chong YJ, Harith HH, Israf DA, Tham CL
Abstract
Sepsis refers to organ failure due to uncontrolled body immune responses towards infection. The systemic inflammatory response triggered by pathogen-associated molecular patterns (PAMPs), such as lipopolysaccharide (LPS) from Gram-negative bacteria, is accompanied by the release of various proinflammatory mediators that can lead to organ damage. The progression to septic shock is even more life-threatening due to hypotension. Thus, sepsis is a leading cause of death and morbidity globally. However, current therapies are mainly symp...
Source: Evidence-based Complementary and Alternative Medicine - November 18, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Therapeutic Approach against 2019-nCoV by Inhibition of ACE-2 Receptor
Drug Res (Stuttg) DOI: 10.1055/a-1275-0228The continued spread of 2019-nCoV has prompted widespread concern around the world. WHO formally named COVID-19 and International Committee on Taxonomy called it Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Due to this viral attack, the whole world is in lockdown. Presently, there is no effective way to control it, except social distancing and hygienic activity. World class scientists and researchers are trying to make vaccine and discover the medicine against the control and cure to this deadly viral disease. Our aim to presenting this article is kick-off deadly v...
Source: Drug Research - November 12, 2020 Category: Drugs & Pharmacology Authors: Kumar, Gajendra Kumar, Dharmendra Singh, Netra Pal Tags: Original Article Source Type: research
