A Unifying Perspective in Blunting the Limited Oral Bioavailability of Curcumin: A Succinct Look
CONCLUSION: In light of current challenges, the major concern pertaining to poor systemic bioavailability of curcumin, its improvement especially in combination with piperine, and necessity of additional research in this setting are together described in this review. Besides, the recent advances on the potential therapeutic rationale and efficacy of curcumin-piperine combination, a promising duo, against various pathologic conditions are delineated.PMID:36017834 | DOI:10.2174/1389200223666220825101212 (Source: Current Drug Metabolism)
Source: Current Drug Metabolism - August 26, 2022 Category: Drugs & Pharmacology Authors: Pitchai Balakumar Taha Alqahtani Ali Alqahtani R Sulochana Lakshmiraj Gurfateh Singh Mani Rupeshkumar A Thangathirupathi Karupiah Sundram Source Type: research
Clinical Evaluation of a Novel Tablet Formulation of Traditional Thai Polyherbal Medicine Named Nawametho in Comparison with Its Decoction in the Treatment of Hyperlipidemia
Evid Based Complement Alternat Med. 2022 Aug 3;2022:2530266. doi: 10.1155/2022/2530266. eCollection 2022.ABSTRACTIn the traditional medical system in Thailand, medicinal plants and polyherbal medicines have been prescribed as lipid-lowering agents, including Nawametho decoction. This polyherbal formulation is described in the Worayokasan scripture. It consists of nine medicinal plants (Aegle marmelos (L.), Carthamus tinctorius L., Hibiscus sabdariffa Linn., Phyllanthus emblica L., Piper longum L., Piper nigrum L., Terminalia bellirica (Gaertn.) Roxb., Terminalia chebula Retz., and Zingiber officinale Roscoe). Apart from it...
Source: Evidence-based Complementary and Alternative Medicine - August 15, 2022 Category: Complementary Medicine Authors: Patcharawalai Jaisamut Channong Tohlang Subhaphorn Wanna Acharaporn Thanakun Thawatchai Srisuwan Surasak Limsuwan Wissava Rattanachai Jarinee Suwannachot Sasitorn Chusri Source Type: research
Development of mouse model for oral allergy syndrome to identify IgE cross-reactive pollen and food allergens: ragweed pollen cross-reacts with fennel and black pepper
In conclusion, we developed mouse model of OAS to identify IgE cross-reactive pollen and food allergens, which will help understand the pathogenesis of OAS/PFAS. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - July 25, 2022 Category: Allergy & Immunology Source Type: research
Expression profiling of immune genes associated with black pepper ( < em > Piper nigrum < /em > ) powder supplementation in the diets of broiler chickens
Anim Biotechnol. 2022 Jun 22:1-7. doi: 10.1080/10495398.2022.2088551. Online ahead of print.ABSTRACTThe present study was conducted on three hundred commercial broiler chicks with the aim to evaluate the effect of black pepper supplementation on expression of TLR gene where the negative control (T1) group was given basal diet without antibiotic and in the control group (T2) basal diet with antibiotic was fed, third (T3), fourth (T4), fifth (T5) and sixth (T6) groups were supplemented with black pepper powder (BPP) at levels 0.25, 0.5, 0.75 and 1%, respectively in diet. After 42 days, a significant reduction (p < 0.05) i...
Source: Animal Biotechnology - June 22, 2022 Category: Biotechnology Authors: Gunjan Chalana Sajjan Sihag Aman Kumar Ankit Magotra Source Type: research
Evaluation of < em > In Vitro < /em > Antiprotease Activity of Selected Traditional Medicinal Herbs in Dentistry and Its In Silico PASS Prediction
CONCLUSION: Hence, our results show the importance of traditional plants Azadirachta indica, Terminalia chebula, green tea, and Piper nigrum to control oral disease conditions. As they show significant protease inhibition activity, hence, the active ingredient could act as a potential anti-inflammatory agent and further help to prevent or control oral disease conditions such as gingivitis and periodontitis.PMID:35707383 | PMC:PMC9192215 | DOI:10.1155/2022/5870443 (Source: Biomed Res)
Source: Biomed Res - June 16, 2022 Category: Research Authors: Ali A Assiry Shaeesta Khaleelahmed Bhavikatti Fahad A Althobaiti Roshan Noor Mohamed Mohmed Isaqali Karobari Source Type: research
Evaluation of < em > In Vitro < /em > Antiprotease Activity of Selected Traditional Medicinal Herbs in Dentistry and Its In Silico PASS Prediction
CONCLUSION: Hence, our results show the importance of traditional plants Azadirachta indica, Terminalia chebula, green tea, and Piper nigrum to control oral disease conditions. As they show significant protease inhibition activity, hence, the active ingredient could act as a potential anti-inflammatory agent and further help to prevent or control oral disease conditions such as gingivitis and periodontitis.PMID:35707383 | PMC:PMC9192215 | DOI:10.1155/2022/5870443 (Source: Biomed Res)
Source: Biomed Res - June 16, 2022 Category: Research Authors: Ali A Assiry Shaeesta Khaleelahmed Bhavikatti Fahad A Althobaiti Roshan Noor Mohamed Mohmed Isaqali Karobari Source Type: research
In vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from hospitalized patients with CDI
CONCLUSION: Essential oils of wild oregano, black pepper and garlic are candidates for adjunctive therapeutics in the treatment of CDI. Oregano oil should certainly be preferred due to the lack of selectivity of action in relation to the ribotype, the strength of the produced biofilm and/or antibiotic-susceptibility patterns.PMID:35709937 | DOI:10.1016/j.anaerobe.2022.102604 (Source: Anaerobe)
Source: Anaerobe - June 16, 2022 Category: Microbiology Authors: Ana Aleksi ć Zorica Stojanovi ć-Radić Celine Harmanus EdJ Kuijper Predrag Stojanovi ć Source Type: research
In vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from hospitalized patients with CDI
CONCLUSION: Essential oils of wild oregano, black pepper and garlic are candidates for adjunctive therapeutics in the treatment of CDI. Oregano oil should certainly be preferred due to the lack of selectivity of action in relation to the ribotype, the strength of the produced biofilm and/or antibiotic-susceptibility patterns.PMID:35709937 | DOI:10.1016/j.anaerobe.2022.102604 (Source: Anaerobe)
Source: Anaerobe - June 16, 2022 Category: Microbiology Authors: Ana Aleksi ć Zorica Stojanovi ć-Radić Celine Harmanus EdJ Kuijper Predrag Stojanovi ć Source Type: research
In vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from hospitalized patients with CDI
CONCLUSION: Essential oils of wild oregano, black pepper and garlic are candidates for adjunctive therapeutics in the treatment of CDI. Oregano oil should certainly be preferred due to the lack of selectivity of action in relation to the ribotype, the strength of the produced biofilm and/or antibiotic-susceptibility patterns.PMID:35709937 | DOI:10.1016/j.anaerobe.2022.102604 (Source: Anaerobe)
Source: Anaerobe - June 16, 2022 Category: Microbiology Authors: Ana Aleksi ć Zorica Stojanovi ć-Radić Celine Harmanus EdJ Kuijper Predrag Stojanovi ć Source Type: research
In vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from hospitalized patients with CDI
CONCLUSION: Essential oils of wild oregano, black pepper and garlic are candidates for adjunctive therapeutics in the treatment of CDI. Oregano oil should certainly be preferred due to the lack of selectivity of action in relation to the ribotype, the strength of the produced biofilm and/or antibiotic-susceptibility patterns.PMID:35709937 | DOI:10.1016/j.anaerobe.2022.102604 (Source: Anaerobe)
Source: Anaerobe - June 16, 2022 Category: Microbiology Authors: Ana Aleksi ć Zorica Stojanovi ć-Radić Celine Harmanus EdJ Kuijper Predrag Stojanovi ć Source Type: research
In vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from hospitalized patients with CDI
CONCLUSION: Essential oils of wild oregano, black pepper and garlic are candidates for adjunctive therapeutics in the treatment of CDI. Oregano oil should certainly be preferred due to the lack of selectivity of action in relation to the ribotype, the strength of the produced biofilm and/or antibiotic-susceptibility patterns.PMID:35709937 | DOI:10.1016/j.anaerobe.2022.102604 (Source: Anaerobe)
Source: Anaerobe - June 16, 2022 Category: Microbiology Authors: Ana Aleksi ć Zorica Stojanovi ć-Radić Celine Harmanus EdJ Kuijper Predrag Stojanovi ć Source Type: research
In vitro anti-clostridial action and potential of the spice herbs essential oils to prevent biofilm formation of hypervirulent Clostridioides difficile strains isolated from hospitalized patients with CDI
CONCLUSION: Essential oils of wild oregano, black pepper and garlic are candidates for adjunctive therapeutics in the treatment of CDI. Oregano oil should certainly be preferred due to the lack of selectivity of action in relation to the ribotype, the strength of the produced biofilm and/or antibiotic-susceptibility patterns.PMID:35709937 | DOI:10.1016/j.anaerobe.2022.102604 (Source: Anaerobe)
Source: Anaerobe - June 16, 2022 Category: Microbiology Authors: Ana Aleksi ć Zorica Stojanovi ć-Radić Celine Harmanus EdJ Kuijper Predrag Stojanovi ć Source Type: research
ViphyllinTM, a Standardized Black Pepper Extract Exerts Antihyperglycemic Effect and Improves Sciatic Nerve Conduction in High Fat Diet/Streptozotocin-Induced Diabetic Model Rats
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - June 14, 2022 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Health Risks for a Rural Community in Bokkos, Plateau State, Nigeria, Exposed to Potentially Toxic Elements from an Abandoned Tin Mine
This study was designed to determine the level of Potentially Toxic Elements (PTEs) contamination in pond water, soil, and food crops and assess the health risk of inhabitants in the abandoned tin mining community in Bokkos LGA. Samples of the mining pond water, soil, and selected food crops from farms irrigated with the pond water: bitter leaf (Vernonia amygdalina), pepper (Piper nigrum), okra (Albelmoschus esculentus), maize (Zea mays), sweet potato (Ipomoea batatas), and Irish potato (Solanum tuberosum) were analyzed for each of the eight PTEs (viz. Cu, Cr, Fe, Mn, Ni, Zn, Cd, and Pb) using inductively coupled plasma op...
Source: Archives of Environmental Contamination and Toxicology - June 9, 2022 Category: Environmental Health Authors: Simon Gabriel Mafulul Johannes H Potgieter Ishaya Yohanna Longdet Zebulon S C Okoye Sanja S Potgieter-Vermaak Source Type: research
