Pesticide residue analysis in different spice samples by automatic µSPE clean-up workflow determination using LC-MS/MS
In this study, sample extracts from spice matrices (paprika/curry/turmeric/dry chilli/black pepper) were cleaned up by an automated µSPE clean-up method for multi-residue analysis of pesticides using LC-MS/MS. The automated µSPE clean-up method involves pre-filled cartridges containing various sorbent materials suitable for numerous co-extractives and the automated clean-up process was carried out using an autosampler. The regulatory limit for pesticides in spices varies with type, with a low MRL of 0.05 mg kg-1 or higher for 99% of the analytes. At spiking concentrations of 0.05 and 0.1 mg kg-1, good recoveries between ...
Source: Analytical and Bioanalytical Chemistry - September 12, 2023 Category: Chemistry Authors: Lorena Manzano-S ánchez Suganthi Angappan Jos é Antonio Martínez Ana Del Real Aguilera Amadeo Rodr íguez Fernández-Alba Source Type: research

Molecules, Vol. 28, Pages 6569: Bioactive Properties, Bioavailability Profiles, and Clinical Evidence of the Potential Benefits of Black Pepper (Piper nigrum) and Red Pepper (Capsicum annum) against Diverse Metabolic Complications
Jeanine L. Marnewick Albertus K. Basson Luca Tiano The consumption of food-derived products, including the regular intake of pepper, is increasingly evaluated for its potential benefits in protecting against diverse metabolic complications. The current study made use of prominent electronic databases including PubMed, Google Scholar, and Scopus to retrieve clinical evidence linking the intake of black and red pepper with the amelioration of metabolic complications. The findings summarize evidence supporting the beneficial effects of black pepper (Piper nigrum L.), including its active ingredient, piperine, in impro...
Source: Molecules - September 11, 2023 Category: Chemistry Authors: Phiwayinkosi V. Dludla Ilenia Cirilli Fabio Marcheggiani Sonia Silvestri Patrick Orlando Ndivhuwo Muvhulawa Marakiya T. Moetlediwa Bongani B. Nkambule Sithandiwe E. Mazibuko-Mbeje Nokulunga Hlengwa Sidney Hanser Duduzile Ndwandwe Jeanine L. Marnewick Albe Tags: Review Source Type: research

Terpenoids as Human Neutrophil Elastase (HNE) Inhibitors: a comprehensive review of Natural Anti-inflammatory Isoprenoids
Chembiochem. 2023 Aug 29:e202300346. doi: 10.1002/cbic.202300346. Online ahead of print.ABSTRACTHuman neutrophil elastase (HNE) is an enzyme that plays key role in the body's inflammatory response. It has been linked to a number of diseases such as chronic obstructive pulmonary disease (COPD), emphysema, and cystic fibrosis. As potential treatments for these diseases, HNE inhibitors are of great interest. Metabolites derived from plants, particularly terpenoids such as β-caryophyllene found in black pepper and other plants, and geraniol present in several essential oils, are recognized as significant sources of inhibitors...
Source: Chembiochem - August 29, 2023 Category: Biochemistry Authors: Muhammad Imran Tousif Mamona Nazir Naheed Riaz Muhammad Saleem Saba Tauseef Sheikh Muhammad Azam Mirza Arfan Yawer Gokhan Zengin Source Type: research

Terpenoids as Human Neutrophil Elastase (HNE) Inhibitors: a comprehensive review of Natural Anti-inflammatory Isoprenoids
Chembiochem. 2023 Aug 29:e202300346. doi: 10.1002/cbic.202300346. Online ahead of print.ABSTRACTHuman neutrophil elastase (HNE) is an enzyme that plays key role in the body's inflammatory response. It has been linked to a number of diseases such as chronic obstructive pulmonary disease (COPD), emphysema, and cystic fibrosis. As potential treatments for these diseases, HNE inhibitors are of great interest. Metabolites derived from plants, particularly terpenoids such as β-caryophyllene found in black pepper and other plants, and geraniol present in several essential oils, are recognized as significant sources of inhibitors...
Source: Chembiochem - August 29, 2023 Category: Biochemistry Authors: Muhammad Imran Tousif Mamona Nazir Naheed Riaz Muhammad Saleem Saba Tauseef Sheikh Muhammad Azam Mirza Arfan Yawer Gokhan Zengin Source Type: research

Radioprotective effect of piperine, as a major component of black pepper, against radiation-induced colon injury: biochemical and histological studies
CONCLUSION: Based on this study, it is concluded that piperine, at low dose, with its antioxidant properties, could reduce the colon damage caused by radiation.PMID:37489775 | DOI:10.2174/1874471016666230725112319 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - July 25, 2023 Category: Radiology Authors: Asal Safarbalou Fatemeh Ebrahimi Fereshteh Talebpour Amiri Seyed Jalal Hosseinimehr Source Type: research