Analytical and Bioanalytical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Mapping elemental solutes at sub-picogram levels during aqueous corrosion of Al alloys using diffusive gradients in thin films (DGT) with LA-ICP-MS
Anal Bioanal Chem. 2024 Apr 16. doi: 10.1007/s00216-024-05288-8. Online ahead of print.ABSTRACTA novel approach using diffusive gradients in thin films (DGT) with laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) for two-dimensional mapping of elemental solute release at sub-picogram levels during aqueous corrosion of Al alloys is presented. Evaluation of different DGT gels with mixed micro-sized binding phases (polyacrylamide-Chelex-Metsorb, polyurethane (PU)-Chelex-Metsorb, PU-Chelex-Zr(OH)4) demonstrated the superior performance of PU gels due to their tear-proof handling, low shrinkage, and compli...
Source: Analytical and Bioanalytical Chemistry - April 16, 2024 Category: Chemistry Authors: Gulnaz Mukhametzianova Stefan Wagner Magdalena Eskinja Masoud Moshtaghi Gregor Mori Thomas Prohaska Source Type: research

A sensitive fluorescence biosensor based on ligation-transcription and CRISPR/Cas13a-assisted cascade amplification strategies to detect the H1N1 virus
Anal Bioanal Chem. 2024 Apr 13. doi: 10.1007/s00216-024-05269-x. Online ahead of print.ABSTRACTWe propose a sensitive H1N1 virus fluorescence biosensor based on ligation-transcription and CRISPR/Cas13a-assisted cascade amplification strategies. Products are generated via the hybridization of single-stranded DNA (ssDNA) probes containing T7 promoter and crRNA templates to a target RNA sequence using SplintR ligase. This generates large crRNA quantities in the presence of T7 RNA polymerase. At such crRNA quantities, ternary Cas13a, crRNA, and activator complexes are successfully constructed and activate Cas13a to enhance flu...
Source: Analytical and Bioanalytical Chemistry - April 13, 2024 Category: Chemistry Authors: Lulu Xue Shengjun Bu Mengyao Xu Jiaqi Wei Hongyu Zhou Yao Xu Zhuo Hao Zehong Li Jiayu Wan Source Type: research

Tailoring the d-band center on Ru < sub > 1 < /sub > Cu single-atom alloy nanotubes for boosting electrochemical non-enzymatic glucose sensing
Anal Bioanal Chem. 2024 Apr 13. doi: 10.1007/s00216-024-05284-y. Online ahead of print.ABSTRACTThe development of cost-effective and highly efficient electrocatalysts is critical to help electrochemical non-enzymatic sensors achieve high performance. Here, a new class of catalyst, Ru single atoms confined on Cu nanotubes as a single-atom alloy (Ru1Cu NTs), with a unique electronic structure and property, was developed to construct a novel electrochemical non-enzymatic glucose sensor for the first time. The Ru1Cu NTs with a diameter of about 24.0 nm showed a much lower oxidation potential (0.38 V) and 9.0-fold higher respon...
Source: Analytical and Bioanalytical Chemistry - April 13, 2024 Category: Chemistry Authors: Shuang Zhang Yunhao Jiang Wenli Lei Yueming Zhai Juejing Liu Xingyi Lyu Tao Li Xiaofeng Guo Yuanmeng Zhao Changsheng Shan Li Niu Source Type: research

Recent progress on charge transfer engineering in reticular framework for efficient electrochemiluminescence
Anal Bioanal Chem. 2024 Apr 13. doi: 10.1007/s00216-024-05279-9. Online ahead of print.ABSTRACTElectrochemiluminescence (ECL) is a luminescence production technique triggered by electrochemistry, which has emerged as a powerful analytical technique in bioanalysis and clinical diagnosis. During ECL, charge transfer (CT) is an important process between electrochemical excitation and luminescent emission, and dramatically affects the efficiency of exciton generation, playing a pivotal role in the light-emitting properties of nanomaterials. Reticular framework materials with intramolecular/intermolecular interactions offer a p...
Source: Analytical and Bioanalytical Chemistry - April 13, 2024 Category: Chemistry Authors: Xinzhou Huang Qian Sun Jinjin Zhao Guoqiu Wu Yuanjian Zhang Yanfei Shen Source Type: research

An amino-rich polymer-coated magnetic nanomaterial for ultra-rapid separation of phosphorylated peptides in the serum of Parkinson's disease patients
Anal Bioanal Chem. 2024 Apr 12. doi: 10.1007/s00216-024-05287-9. Online ahead of print.ABSTRACTThe elucidation of disease pathogenesis can be achieved by analyzing the low-abundance phosphopeptides in organisms. Herein, we developed a novel and easy-to-prepare polymer-coated nanomaterial. By improving the hydrophilicity and spatial conformation of the material, we effectively enhanced the adsorption of phosphopeptides and demonstrated excellent enrichment properties. The material was able to successfully enrich the phosphopeptides in only 1 min. Meanwhile, the material has high selectivity (1:2000), good loading capacity (...
Source: Analytical and Bioanalytical Chemistry - April 12, 2024 Category: Chemistry Authors: Xiaoya Zhang Bing Wang Yiting Luo Chuan-Fan Ding Yinghua Yan Source Type: research

Python workflow for the selection and identification of marker peptides-proof-of-principle study with heated milk
Anal Bioanal Chem. 2024 Apr 12. doi: 10.1007/s00216-024-05286-w. Online ahead of print.ABSTRACTThe analysis of almost holistic food profiles has developed considerably over the last years. This has also led to larger amounts of data and the ability to obtain more information about health-beneficial and adverse constituents in food than ever before. Especially in the field of proteomics, software is used for evaluation, and these do not provide specific approaches for unique monitoring questions. An additional and more comprehensive way of evaluation can be done with the programming language Python. It offers broad possibil...
Source: Analytical and Bioanalytical Chemistry - April 12, 2024 Category: Chemistry Authors: Gesine Kuhnen Lisa-Carina Class Svenja Badekow Kim Lara Hanisch Sascha Rohn J ürgen Kuballa Source Type: research

The mechanism of intrinsic peroxidase (POD)-like activity of attapulgite
This study serves as a novel reference for the future design and performance optimization of nanozymes that are based on ATP and clay minerals.PMID:38602542 | DOI:10.1007/s00216-024-05280-2 (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - April 11, 2024 Category: Chemistry Authors: Feng Feng Yihe Zhang Xiao Zhang Bin Mu Qi An Peixia Wang Source Type: research

Recent advances in near-infrared I/II persistent luminescent nanoparticles for biosensing and bioimaging in cancer analysis
Anal Bioanal Chem. 2024 Apr 9. doi: 10.1007/s00216-024-05267-z. Online ahead of print.ABSTRACTPhotoluminescent materials (PLNs) are photoluminescent materials that can absorb external excitation light, store it, and slowly release it in the form of light in the dark to achieve long-term luminescence. Developing near-infrared (NIR) PLNs is critical to improving long-afterglow luminescent materials. Because they excite in vitro, NIR-PLNs have the potential to avoid interference from in vivo autofluorescence in biomedical applications. These materials are promising for biosensing and bioimaging applications by exploiting the ...
Source: Analytical and Bioanalytical Chemistry - April 9, 2024 Category: Chemistry Authors: Ming-Hsien Chan Yu-Chan Chang Source Type: research

In-line coupling of capillary-channeled polymer fiber columns with optical absorbance and multi-angle light scattering detection for the isolation and characterization of exosomes
Anal Bioanal Chem. 2024 Apr 9. doi: 10.1007/s00216-024-05283-z. Online ahead of print.ABSTRACTExtracellular vesicles (EVs) have garnered much interest due to their fundamental role in intracellular communication and their potential utility in clinical diagnostics and as biotherapeutic vectors. Of particular relevance is the subset of EVs referred to as exosomes, ranging in size from 30 to 150 nm, which contain incredible amounts of information about their cell of origin, which can be used to track the progress of disease. As a complementary action, exosomes can be engineered with therapeutic cargo to selectively target dis...
Source: Analytical and Bioanalytical Chemistry - April 9, 2024 Category: Chemistry Authors: Sarah K Wysor R Kenneth Marcus Source Type: research