Isolation, characterization and in vitro antioxidant activity screening of pure compound from black pepper (Piper nigrum)
Environ Sci Pollut Res Int. 2022 Mar 8. doi: 10.1007/s11356-022-19403-8. Online ahead of print.ABSTRACTThe present study's aims of isolation, characterization and in vitro antioxidant activity screening of pure compound from Black pepper (Piper nigrum) were investigated. Nowadays, scientific exploration of medicinal plants from natural sources has become the prime concern globally. All the crude drugs that have been isolated from natural plant origin (herbs, root, stem, bark, fruit and flower) have great significance in drug discovery as well as a lead compound to demonstrate great synergistic effect on pharmacology. For t...
Source: Environmental Science and Pollution Research International - March 9, 2022 Category: Environmental Health Authors: Murshida Mollik Md Habibur Rahman Majed Al-Shaeri Ghulam Md Ashraf Athanasios Alexiou Md Abdul Gafur Source Type: research
Protective effects of functional foods against Parkinson's disease: A narrative review on pharmacology, phytochemistry, and molecular mechanisms
Phytother Res. 2022 Mar 4. doi: 10.1002/ptr.7425. Online ahead of print.ABSTRACTIn Persian Medicine (PM), PD (brain-based tremor) is a known CNS disorder with several therapeutic and preventive options. In their medical textbooks and pharmacopeias, Persian great scientists such as Rhazes (854-925 AD), Avicenna (980-1037 AD), and Jorjani (1042-1136 AD), have discussed pharmacological and nutritional strategies for the prevention, slowing progression, and treatment of PD. In the present study, we surveyed plant- and animal-based foods recommended by PM for the prevention and treatment of CNS-related tremors. In vivo and in-v...
Source: Cell Research - March 4, 2022 Category: Cytology Authors: Milad Iranshahy Behjat Javadi Amirhossein Sahebkar Source Type: research
Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity
Curr Opin Pharmacol. 2022 Mar 1;63:102187. doi: 10.1016/j.coph.2022.102187. Online ahead of print.ABSTRACTCardio-oncology is an emerging field that mainly focuses on a series of cardiovascular diseases caused by chemotherapy and radiotherapy. In the history and culture of human nutrition, spices have been emphasized for their wide range of economic and medical applications in addition to being used as a food-flavoring agent and food preservative. Currently, an increasing number of studies have focused on the health benefits of spices in preventing cardiovascular diseases, particularly their antioxidant effects against card...
Source: Current Opinion in Pharmacology - March 4, 2022 Category: Drugs & Pharmacology Authors: Jia Liu Qing Zhang Ting Tao Ling-Yu Wang Jia-Yi Sun Chun-Jie Wu Wen-Jun Zou Source Type: research
Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity
Curr Opin Pharmacol. 2022 Mar 1;63:102187. doi: 10.1016/j.coph.2022.102187. Online ahead of print.ABSTRACTCardio-oncology is an emerging field that mainly focuses on a series of cardiovascular diseases caused by chemotherapy and radiotherapy. In the history and culture of human nutrition, spices have been emphasized for their wide range of economic and medical applications in addition to being used as a food-flavoring agent and food preservative. Currently, an increasing number of studies have focused on the health benefits of spices in preventing cardiovascular diseases, particularly their antioxidant effects against card...
Source: Current Opinion in Pharmacology - March 4, 2022 Category: Drugs & Pharmacology Authors: Jia Liu Qing Zhang Ting Tao Ling-Yu Wang Jia-Yi Sun Chun-Jie Wu Wen-Jun Zou Source Type: research
Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity
Curr Opin Pharmacol. 2022 Mar 1;63:102187. doi: 10.1016/j.coph.2022.102187. Online ahead of print.ABSTRACTCardio-oncology is an emerging field that mainly focuses on a series of cardiovascular diseases caused by chemotherapy and radiotherapy. In the history and culture of human nutrition, spices have been emphasized for their wide range of economic and medical applications in addition to being used as a food-flavoring agent and food preservative. Currently, an increasing number of studies have focused on the health benefits of spices in preventing cardiovascular diseases, particularly their antioxidant effects against card...
Source: Current Opinion in Pharmacology - March 4, 2022 Category: Drugs & Pharmacology Authors: Jia Liu Qing Zhang Ting Tao Ling-Yu Wang Jia-Yi Sun Chun-Jie Wu Wen-Jun Zou Source Type: research
< em > Ocimum sanctum < /em > , < em > Zingiber officinale, < /em > and < em > Piper nigrum < /em > extracts and their effects on gut microbiota modulations (prebiotic potential), basal inflammatory markers and lipid levels: oral supplementation study in healthy rats
CONCLUSIONS: The current study could be first of its kind in exploring prebiotic potential of OS, ZO, PN and their effect on native gut bacterial population.PMID:35188051 | DOI:10.1080/13880209.2022.2033797 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - February 21, 2022 Category: Drugs & Pharmacology Authors: Narendra Babu Kondapalli Rajkumar Hemalatha Satyanarayana Uppala Srinivas Reddy Yathapu Shujauddin Mohammed Mullapudi Venkata Surekha Ananthan Rajendran Dinesh Kumar Bharadwaj Source Type: research
< em > Ocimum sanctum < /em > , < em > Zingiber officinale, < /em > and < em > Piper nigrum < /em > extracts and their effects on gut microbiota modulations (prebiotic potential), basal inflammatory markers and lipid levels: oral supplementation study in healthy rats
CONCLUSIONS: The current study could be first of its kind in exploring prebiotic potential of OS, ZO, PN and their effect on native gut bacterial population.PMID:35188051 | PMC:PMC8865113 | DOI:10.1080/13880209.2022.2033797 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - February 21, 2022 Category: Drugs & Pharmacology Authors: Narendra Babu Kondapalli Rajkumar Hemalatha Satyanarayana Uppala Srinivas Reddy Yathapu Shujauddin Mohammed Mullapudi Venkata Surekha Ananthan Rajendran Dinesh Kumar Bharadwaj Source Type: research
Uniform rod and spherical nanocrystalline celluloses from hydrolysis of industrial pepper waste (Piper nigrum L.) using organic acid and inorganic acid
This study highlighted the role of acidity strength for organic acid and inorganic acid in controlling the level of hydrogen bond dissociation and the dissolution of amorphous fragments, which consequently directing the morphology and the physicochemical properties of NCCs.PMID:35157900 | DOI:10.1016/j.ijbiomac.2022.02.045 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - February 14, 2022 Category: Biochemistry Authors: Holilah Holilah Hasliza Bahruji Ratna Ediati Asranudin Asranudin Aishah Abdul Jalil Bambang Piluharto Reva Edra Nugraha Didik Prasetyoko Source Type: research
ViphyllinTM, a Standardized Black Pepper Seed Extract Exerts Antinociceptive Effects in Murine Pain Models via Activation of Cannabinoid Receptor CB2, Peroxisome Proliferator-Activated Receptor-Alpha and TRPV1 Ion Channels
(Source: Journal of Pain Research)
Source: Journal of Pain Research - February 4, 2022 Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
TLC-Based Metabolite Profiling and Bioactivity-Based Scientific Validation for Use of Water Extracts in AYUSH Formulations
Evid Based Complement Alternat Med. 2021 Dec 31;2021:2847440. doi: 10.1155/2021/2847440. eCollection 2021.ABSTRACTWe aimed to develop a chromatographic method for scientific validation of water extract of some important Indian traditional plants used in AYUSH-based formulation as immunomodulator and to evaluate their bioactive potential. Fruits of Phyllanthus emblica L. and Piper nigrum L., stem of Tinospora cordifolia (Willd.) Miers, rhizome of Curcuma longa L., leaves of Ocimum sanctum L. and Achillea millefolium L., roots of Withania somnifera L., and stem bark of Azadirachta indica A. Juss. were coarsely powdered and e...
Source: Evidence-based Complementary and Alternative Medicine - January 10, 2022 Category: Complementary Medicine Authors: Sultan Zahiruddin Abida Parveen Washim Khan Rabea Parveen Sayeed Ahmad Source Type: research
Folic acid-modified photoluminescent dialdehyde carboxymethyl cellulose crosslinked bionanogels for pH-controlled and tumor-targeted co-drug delivery
Int J Biol Macromol. 2022 Jan 7;200:247-262. doi: 10.1016/j.ijbiomac.2022.01.002. Online ahead of print.ABSTRACTThis work aimed to fabricate a new photoluminescent bionanogel with both targeted anticancer drug delivery and bioimaging potentials. Briefly, at first photoluminescent carbon dots (CDs) were synthesized from the low-cost and more available black pepper with traditional medicinal properties. The as-synthesized dialdehyde carboxymethyl cellulose (DCMC) was used as a safe crosslinker for gelatin crosslinking in the presence of CDs (CDs/DCMC-Gel). Eventually, the residual amine functional groups of gelatin were used...
Source: International Journal of Biological Macromolecules - January 10, 2022 Category: Biochemistry Authors: Malihe Pooresmaeil Hassan Namazi Source Type: research
