Elucidating the role of < em > Rhodiola rosea < /em > L. in sepsis-induced acute lung injury via network pharmacology: emphasis on inflammatory response, oxidative stress, and the PI3K-AKT pathway
CONCLUSION: This study provides foundational knowledge of the effective components, potential targets, and molecular mechanisms of RR against ALI, which could be critical for developing targeted therapeutic strategies for sepsis-induced ALI.PMID:38445620 | PMC:PMC10919309 | DOI:10.1080/13880209.2024.2319117 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - March 6, 2024 Category: Drugs & Pharmacology Authors: Lu Jiang Dongdong Yang Zhuoyi Zhang Liying Xu Qingyu Jiang Yixin Tong Lanzhi Zheng Source Type: research

Elucidating the role of < em > Rhodiola rosea < /em > L. in sepsis-induced acute lung injury via network pharmacology: emphasis on inflammatory response, oxidative stress, and the PI3K-AKT pathway
CONCLUSION: This study provides foundational knowledge of the effective components, potential targets, and molecular mechanisms of RR against ALI, which could be critical for developing targeted therapeutic strategies for sepsis-induced ALI.PMID:38445620 | DOI:10.1080/13880209.2024.2319117 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - March 6, 2024 Category: Drugs & Pharmacology Authors: Lu Jiang Dongdong Yang Zhuoyi Zhang Liying Xu Qingyu Jiang Yixin Tong Lanzhi Zheng Source Type: research

Statement of Retraction: Pristimerin inhibits neuronal inflammation and protects cognitive function in mice with sepsis-induced brain injuries by regulating PI3K/Akt  signalling
Pharm Biol. 2024 Dec;62(1):269. doi: 10.1080/13880209.2024.2323353. Epub 2024 Mar 5.NO ABSTRACTPMID:38441034 | DOI:10.1080/13880209.2024.2323353 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - March 5, 2024 Category: Drugs & Pharmacology Source Type: research

Correction
Pharm Biol. 2024 Dec;62(1):270-271. doi: 10.1080/13880209.2024.2323905. Epub 2024 Feb 29.NO ABSTRACTPMID:38421938 | PMC:PMC10906113 | DOI:10.1080/13880209.2024.2323905 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - February 29, 2024 Category: Drugs & Pharmacology Source Type: research

Correction
Pharm Biol. 2024 Dec;62(1):270-271. doi: 10.1080/13880209.2024.2323905. Epub 2024 Feb 29.NO ABSTRACTPMID:38421938 | DOI:10.1080/13880209.2024.2323905 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - February 29, 2024 Category: Drugs & Pharmacology Source Type: research

Notoginsenoside R1 improves intestinal microvascular functioning in sepsis by targeting Drp1-mediated mitochondrial quality imbalance
CONCLUSIONS: Drp1-mediated mitochondrial quality imbalance is a potential therapeutic target for sepsis. Small molecule natural drugs like NGR1 targeting Drp1 may offer new directions for organ protection following sepsis. Future research should focus on clinical trials to evaluate NGR1's efficacy across various patient populations, potentially leading to novel treatments for sepsis.PMID:38389274 | PMC:PMC10896147 | DOI:10.1080/13880209.2024.2318349 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - February 23, 2024 Category: Drugs & Pharmacology Authors: Dongyao Hou Ruixue Liu Shuai Hao Yong Dou Guizhen Chen Liangming Liu Tao Li Yunxing Cao He Huang Chenyang Duan Source Type: research