Treatment with onion bulb extract both prevents and reverses allergic inflammation in a murine model of asthma
CONCLUSION: Our data show that OBE is an effective anti-inflammatory agent with both therapeutic and preventative anti-asthma effects. These findings imply that onion/OBE may be used as an adjunct therapeutic agent in established asthma and/or to prevent development of allergic asthma. However, further studies to identify the active constituents, and demonstrate proof-of-concept in humans are needed.PMID:38584568 | PMC:PMC11003327 | DOI:10.1080/13880209.2024.2335187 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - April 8, 2024 Category: Drugs & Pharmacology Authors: Ahmed Z El-Hashim Maitham A Khajah Khaled Y Orabi Sowmya Balakrishnan Hanan G Sary Ahmad M Barakat Source Type: research
Treatment with onion bulb extract both prevents and reverses allergic inflammation in a murine model of asthma
CONCLUSION: Our data show that OBE is an effective anti-inflammatory agent with both therapeutic and preventative anti-asthma effects. These findings imply that onion/OBE may be used as an adjunct therapeutic agent in established asthma and/or to prevent development of allergic asthma. However, further studies to identify the active constituents, and demonstrate proof-of-concept in humans are needed.PMID:38584568 | DOI:10.1080/13880209.2024.2335187 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - April 8, 2024 Category: Drugs & Pharmacology Authors: Ahmed Z El-Hashim Maitham A Khajah Khaled Y Orabi Sowmya Balakrishnan Hanan G Sary Ahmad M Barakat Source Type: research
Babaodan overcomes cisplatin resistance in cholangiocarcinoma via inhibiting YAP1
CONCLUSION: This study provides a scientific basis for BBD clinical application and provides a new direction for BBD biological mechanism research.PMID:38571483 | PMC:PMC10997361 | DOI:10.1080/13880209.2024.2331060 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - April 4, 2024 Category: Drugs & Pharmacology Authors: Jiong Li Xiangjun Ma Faying Xu Yuanliang Yan Weiqing Chen Source Type: research
Babaodan overcomes cisplatin resistance in cholangiocarcinoma via inhibiting YAP1
CONCLUSION: This study provides a scientific basis for BBD clinical application and provides a new direction for BBD biological mechanism research.PMID:38571483 | DOI:10.1080/13880209.2024.2331060 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - April 4, 2024 Category: Drugs & Pharmacology Authors: Jiong Li Xiangjun Ma Faying Xu Yuanliang Yan Weiqing Chen Source Type: research
Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification
CONCLUSION: THSWD mitigates hyperpigmentation by targeting ALB, IL6, and MAPK3. This study paves the way for clinical applications of THSWD as a novel treatment for hyperpigmentation and offers new targeted therapeutic strategies.PMID:38555860 | DOI:10.1080/13880209.2024.2330609 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - March 31, 2024 Category: Drugs & Pharmacology Authors: Jun Chen Wenyi Ye Source Type: research
