Novel treatment from a botanical formulation Si-Miao-Yong-an decoction inhibits vasa vasorum angiogenesis and stabilizes atherosclerosis plaques via the Wnt1/ β-catenin signalling pathway
CONCLUSIONS: SMYA has a protective effect against AS, which may be related to its anti-VV angiogenesis in plaques, suggesting that SMYA has the potential as a novel botanical formulation in the treatment of AS.PMID:37651108 | DOI:10.1080/13880209.2023.2249061 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 31, 2023 Category: Drugs & Pharmacology Authors: Zhongwen Qi Zhipeng Yan Ke Zhu Yueyao Wang Yajie Fan Tingting Li Junping Zhang Source Type: research
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1
CONCLUSION: Our findings indicate that EGCG promotes intestinal epithelial cell proliferation and barrier function after I/R injury in vitro and in vivo via activation of Nurr1.PMID:37621064 | PMC:PMC10461505 | DOI:10.1080/13880209.2023.2245445 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jiacheng Gao Yuhang Wang Zirui Jia Jiaming Xue Tingting Zhou Guo Zu Source Type: research
Protective effect and mechanism of styrax on ischemic stroke rats: metabonomic insights by UPLC-Q/TOF-MS analysis
CONCLUSION: Styrax treatment could ameliorate ischemic-stroke rats by intervening with energy metabolism and glutamine metabolism. This can help us understand the mechanism of styrax, inspiring more clinical application and promotion.PMID:37621078 | PMC:PMC10461497 | DOI:10.1080/13880209.2023.2246501 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Fei Mu Rui Lin Xueyan Lu Meina Zhao Jiaxin Zhao Shaojie Huang Chao Guo Yue Guan Haiyue Zhang Miaomiao Xi Jingwen Wang Haifeng Tang Source Type: research
Tormentic acid, a triterpenoid isolated from the fruits of < em > Chaenomeles speciose < /em > , protected indomethacin-induced gastric mucosal lesion via modulating miR-139 and the CXCR4/CXCL12/PLC/PKC/Rho a/MLC pathway
CONCLUSIONS: TA may have potential use as a clinical drug candidate for gastric mucosal lesion treatment.PMID:37623313 | PMC:PMC10461523 | DOI:10.1080/13880209.2023.2249526 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jun-Yu He Jie Li Yuan-Yuan Zhang Hai-Bo He Yu-Min He Dao-Xiang Xu Xiao Wang Hao-Yang Wu Ji-Hong Zhang Hasan Jahid Akter Sadia Hui-Fan Yu Jun-Zhi Wang Kun Zou Source Type: research
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1
CONCLUSION: Our findings indicate that EGCG promotes intestinal epithelial cell proliferation and barrier function after I/R injury in vitro and in vivo via activation of Nurr1.PMID:37621064 | PMC:PMC10461505 | DOI:10.1080/13880209.2023.2245445 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jiacheng Gao Yuhang Wang Zirui Jia Jiaming Xue Tingting Zhou Guo Zu Source Type: research
Protective effect and mechanism of styrax on ischemic stroke rats: metabonomic insights by UPLC-Q/TOF-MS analysis
CONCLUSION: Styrax treatment could ameliorate ischemic-stroke rats by intervening with energy metabolism and glutamine metabolism. This can help us understand the mechanism of styrax, inspiring more clinical application and promotion.PMID:37621078 | PMC:PMC10461497 | DOI:10.1080/13880209.2023.2246501 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Fei Mu Rui Lin Xueyan Lu Meina Zhao Jiaxin Zhao Shaojie Huang Chao Guo Yue Guan Haiyue Zhang Miaomiao Xi Jingwen Wang Haifeng Tang Source Type: research
Tormentic acid, a triterpenoid isolated from the fruits of < em > Chaenomeles speciose < /em > , protected indomethacin-induced gastric mucosal lesion via modulating miR-139 and the CXCR4/CXCL12/PLC/PKC/Rho a/MLC pathway
CONCLUSIONS: TA may have potential use as a clinical drug candidate for gastric mucosal lesion treatment.PMID:37623313 | PMC:PMC10461523 | DOI:10.1080/13880209.2023.2249526 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jun-Yu He Jie Li Yuan-Yuan Zhang Hai-Bo He Yu-Min He Dao-Xiang Xu Xiao Wang Hao-Yang Wu Ji-Hong Zhang Hasan Jahid Akter Sadia Hui-Fan Yu Jun-Zhi Wang Kun Zou Source Type: research
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1
CONCLUSION: Our findings indicate that EGCG promotes intestinal epithelial cell proliferation and barrier function after I/R injury in vitro and in vivo via activation of Nurr1.PMID:37621064 | DOI:10.1080/13880209.2023.2245445 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jiacheng Gao Yuhang Wang Zirui Jia Jiaming Xue Tingting Zhou Guo Zu Source Type: research
Protective effect and mechanism of styrax on ischemic stroke rats: metabonomic insights by UPLC-Q/TOF-MS analysis
CONCLUSION: Styrax treatment could ameliorate ischemic-stroke rats by intervening with energy metabolism and glutamine metabolism. This can help us understand the mechanism of styrax, inspiring more clinical application and promotion.PMID:37621078 | DOI:10.1080/13880209.2023.2246501 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Fei Mu Rui Lin Xueyan Lu Meina Zhao Jiaxin Zhao Shaojie Huang Chao Guo Yue Guan Haiyue Zhang Miaomiao Xi Jingwen Wang Haifeng Tang Source Type: research
Tormentic acid, a triterpenoid isolated from the fruits of < em > Chaenomeles speciose < /em > , protected indomethacin-induced gastric mucosal lesion via modulating miR-139 and the CXCR4/CXCL12/PLC/PKC/Rho a/MLC pathway
CONCLUSIONS: TA may have potential use as a clinical drug candidate for gastric mucosal lesion treatment.PMID:37623313 | DOI:10.1080/13880209.2023.2249526 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jun-Yu He Jie Li Yuan-Yuan Zhang Hai-Bo He Yu-Min He Dao-Xiang Xu Xiao Wang Hao-Yang Wu Ji-Hong Zhang Hasan Jahid Akter Sadia Hui-Fan Yu Jun-Zhi Wang Kun Zou Source Type: research
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1
CONCLUSION: Our findings indicate that EGCG promotes intestinal epithelial cell proliferation and barrier function after I/R injury in vitro and in vivo via activation of Nurr1.PMID:37621064 | DOI:10.1080/13880209.2023.2245445 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jiacheng Gao Yuhang Wang Zirui Jia Jiaming Xue Tingting Zhou Guo Zu Source Type: research
Protective effect and mechanism of styrax on ischemic stroke rats: metabonomic insights by UPLC-Q/TOF-MS analysis
CONCLUSION: Styrax treatment could ameliorate ischemic-stroke rats by intervening with energy metabolism and glutamine metabolism. This can help us understand the mechanism of styrax, inspiring more clinical application and promotion.PMID:37621078 | DOI:10.1080/13880209.2023.2246501 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Fei Mu Rui Lin Xueyan Lu Meina Zhao Jiaxin Zhao Shaojie Huang Chao Guo Yue Guan Haiyue Zhang Miaomiao Xi Jingwen Wang Haifeng Tang Source Type: research
Tormentic acid, a triterpenoid isolated from the fruits of < em > Chaenomeles speciose < /em > , protected indomethacin-induced gastric mucosal lesion via modulating miR-139 and the CXCR4/CXCL12/PLC/PKC/Rho a/MLC pathway
CONCLUSIONS: TA may have potential use as a clinical drug candidate for gastric mucosal lesion treatment.PMID:37623313 | DOI:10.1080/13880209.2023.2249526 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jun-Yu He Jie Li Yuan-Yuan Zhang Hai-Bo He Yu-Min He Dao-Xiang Xu Xiao Wang Hao-Yang Wu Ji-Hong Zhang Hasan Jahid Akter Sadia Hui-Fan Yu Jun-Zhi Wang Kun Zou Source Type: research
(-)-Epigallocatechin-3-gallate promotes intestinal epithelial proliferation and barrier function after ischemia/reperfusion injury via activation of Nurr1
CONCLUSION: Our findings indicate that EGCG promotes intestinal epithelial cell proliferation and barrier function after I/R injury in vitro and in vivo via activation of Nurr1.PMID:37621064 | DOI:10.1080/13880209.2023.2245445 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Jiacheng Gao Yuhang Wang Zirui Jia Jiaming Xue Tingting Zhou Guo Zu Source Type: research
Protective effect and mechanism of styrax on ischemic stroke rats: metabonomic insights by UPLC-Q/TOF-MS analysis
CONCLUSION: Styrax treatment could ameliorate ischemic-stroke rats by intervening with energy metabolism and glutamine metabolism. This can help us understand the mechanism of styrax, inspiring more clinical application and promotion.PMID:37621078 | DOI:10.1080/13880209.2023.2246501 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - August 25, 2023 Category: Drugs & Pharmacology Authors: Fei Mu Rui Lin Xueyan Lu Meina Zhao Jiaxin Zhao Shaojie Huang Chao Guo Yue Guan Haiyue Zhang Miaomiao Xi Jingwen Wang Haifeng Tang Source Type: research
