Evaluation of topical methylene blue nanoemulsion for wound healing in diabetic mice
CONCLUSION: This study provides a foundation for the application of MB-NE in the treatment of DW.PMID:37691404 | DOI:10.1080/13880209.2023.2254341 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 11, 2023 Category: Drugs & Pharmacology Authors: Yu Gao Zhounan Jiang Bin Xu Ran Mo Shiyan Li Yanan Jiang Demei Zhao Wangbin Cao Bin Chen Meng Tian Qian Tan Source Type: research
Integrating serum metabolomics and network analysis to explore the antidepressant activity of crocin in rats with chronic unexpected mild stress-induced depression
CONCLUSIONS: This study provides insights into the antidepressant therapeutic effect of crocin and its underlying mechanisms. The findings contribute to a better understanding of the metabolic mechanism involved in the anti-depressant effect of crocin, establishing a strong foundation for future research in this area.PMID:37688460 | PMC:PMC10494758 | DOI:10.1080/13880209.2023.2246531 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 9, 2023 Category: Drugs & Pharmacology Authors: Yan Luo Ziyan Zhong Huan Li Le Wang Dongwei Guo Xuanqi Dong Jian Liu Mingxia Xie Mei Wu Yun Xiang Xi Zhang Pan Meng Source Type: research
Integrating serum metabolomics and network analysis to explore the antidepressant activity of crocin in rats with chronic unexpected mild stress-induced depression
CONCLUSIONS: This study provides insights into the antidepressant therapeutic effect of crocin and its underlying mechanisms. The findings contribute to a better understanding of the metabolic mechanism involved in the anti-depressant effect of crocin, establishing a strong foundation for future research in this area.PMID:37688460 | DOI:10.1080/13880209.2023.2246531 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 9, 2023 Category: Drugs & Pharmacology Authors: Yan Luo Ziyan Zhong Huan Li Le Wang Dongwei Guo Xuanqi Dong Jian Liu Mingxia Xie Mei Wu Yun Xiang Xi Zhang Pan Meng Source Type: research
Paeoniflorin suppresses the apoptosis and inflammation of human coronary artery endothelial cells induced by oxidized low-density lipoprotein by regulating the Wnt/ β-catenin pathway
CONCLUSIONS: This study first revealed that PF inhibited ox-LDL-induced HCAECs apoptosis and inflammation via the Wnt/β-catenin pathway and alleviated CAD, suggesting the potential of PF as a drug for CAD treatment.PMID:37674320 | PMC:PMC10486282 | DOI:10.1080/13880209.2023.2220360 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 7, 2023 Category: Drugs & Pharmacology Authors: Shasha Liu Ying Li Caojie Wu Source Type: research
Mechanism investigation of Duhuo Jisheng pill against rheumatoid arthritis based on a strategy for the integration of network pharmacology, molecular docking and < em > in vivo < /em > experimental verification
CONCLUSIONS: DHJS could alleviate the collagen-induced arthritis (CIA) by the PI3K/AKT/NF-κB signalling pathway.PMID:37674371 | PMC:PMC10486301 | DOI:10.1080/13880209.2023.2252854 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 7, 2023 Category: Drugs & Pharmacology Authors: Ping Xin Xiaoyun Xu Huaxi Zhang Yuezhou Hu Chengjie Deng Shiqin Sun Shuang Liu Xuegang Zhou Hongxing Ma Xiaoliang Li Source Type: research
Extracts of < em > Thesium chinense < /em > inhibit SARS-CoV-2 and inflammation < em > in vitro < /em >
CONCLUSION: T. chinense can be a potential candidate to fight SARS-CoV-2, and is becoming a traditional Chinese medicine candidate for treating COVID-19.PMID:37675874 | PMC:PMC10486283 | DOI:10.1080/13880209.2023.2253841 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 7, 2023 Category: Drugs & Pharmacology Authors: Juncheng Ma Juanru Wei Gang Chen Xiaowei Yan Hechun Sun Ning Li Source Type: research
Paeoniflorin suppresses the apoptosis and inflammation of human coronary artery endothelial cells induced by oxidized low-density lipoprotein by regulating the Wnt/ β-catenin pathway
CONCLUSIONS: This study first revealed that PF inhibited ox-LDL-induced HCAECs apoptosis and inflammation via the Wnt/β-catenin pathway and alleviated CAD, suggesting the potential of PF as a drug for CAD treatment.PMID:37674320 | DOI:10.1080/13880209.2023.2220360 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - September 7, 2023 Category: Drugs & Pharmacology Authors: Shasha Liu Ying Li Caojie Wu Source Type: research
