Integrating serum metabolomics and network analysis to explore the antidepressant activity of crocin in rats with chronic unexpected mild stress-induced  depression

CONCLUSIONS: This study provides insights into the antidepressant therapeutic effect of crocin and its underlying mechanisms. The findings contribute to a better understanding of the metabolic mechanism involved in the anti-depressant effect of crocin, establishing a strong foundation for future research in this area.PMID:37688460 | DOI:10.1080/13880209.2023.2246531

Source: Pharmaceutical Biology - September 9, 2023 Category: Drugs & Pharmacology Authors: Yan Luo Ziyan Zhong Huan Li Le Wang Dongwei Guo Xuanqi Dong Jian Liu Mingxia Xie Mei Wu Yun Xiang Xi Zhang Pan Meng Source Type: research