Update – Fluoxetine Serious Shortage Protocol extensions
The Department of Health& Social Care (DHSC) has informed us of extensions to the following Serious Shortage Protocols (SSPs). Fluoxetine 40mg capsules The SSP for fluoxetine 40mg capsules is be (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 3, 2020 Category: Drugs & Pharmacology Source Type: news

Effective treatment and prevention of attempted suicide, anxiety and aggressiveness with fluoxetine, despite proven use of androgenic anabolic steroids - Amaral JMX, Padilha MC, Chagas SV, Baker JS, Mullen C, Vieira Neto L, Aquino Neto FR, Cruz MS.
This report includes 30 days of inpatient treatment and a 6-month follow-up. R... (Source: SafetyLit)
Source: SafetyLit - August 21, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Serious shortage protocol (SSP) for fluoxetine - extension
The Department of Health and Social Care (DHSC) issued a Serious Shortage Protocols (SSP) for fluoxetine 40mg capsules. This has been extended to Friday 4 September. Further information on the SSP ca (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - August 11, 2020 Category: Drugs & Pharmacology Source Type: news

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial - AFFINITY Trial Collaboration.
BACKGROUND: Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethni... (Source: SafetyLit)
Source: SafetyLit - July 27, 2020 Category: International Medicine & Public Health Tags: Falls Source Type: news

Serious shortage protocol (SSP) for fluoxetine - extension
The Department of Health and Social Care (DHSC) issued a Serious Shortage Protocols (SSP) for fluoxetine 40mg capsules. This has been extended to Monday 10 August Further information on the SSP can b (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - July 16, 2020 Category: Drugs & Pharmacology Source Type: news

Serious shortage protocol (SSP) for fluoxetine (England) - extension
The Department of Health and Social Care (DHSC) issued a Serious Shortage Protocols (SSP) for fluoxetine 10mg tablets. This has been extended to Friday 11 September 2020. Further information on the S (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - June 2, 2020 Category: Drugs & Pharmacology Source Type: news

Behavioral therapy and fluoxetine treatment in aggressive dogs: a case study - Odore R, Rendini D, Badino P, Gardini G, Cagnotti G, Meucci V, Intorre L, Bellino C, D'Angelo A.
Canine aggression is a major concern, affecting millions of people worldwide, and treatment can be challenging even for skilled veterinarians. Empiric use of fluoxetine is sometimes attempted, although few data regarding long-term effects in aggressive dog... (Source: SafetyLit)
Source: SafetyLit - May 18, 2020 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Fluoxetine Disappoints in Two New Stroke Trials Fluoxetine Disappoints in Two New Stroke Trials
The antidepressant failed to yield improvements in stroke recovery and was associated with an increase in fracture rates in the EFFECTS and AFFINITY studies.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - May 14, 2020 Category: Psychiatry Tags: Neurology & Neurosurgery News Source Type: news

Aurobindo Pharma gets USFDA nod for generic antidepressant tablets
The company has received the final approval from the US Food and Drug Administration (USFDA) to manufacture and market Fluoxetine tablets in the strengths of 10 mg and 20 mg, Aurobindo Pharma said in a filing to BSE. The tablets are generic version of Eli Lilly's Prozac tablets, it added. The product will be launched in April 2020. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - April 9, 2020 Category: Pharmaceuticals Source Type: news

Serious shortage protocol (SSP) for Fluoxetine (England)
The Department of Health and Social Care (DHSC) have decided to issue a Serious Shortage Protocols (SSP)... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - March 12, 2020 Category: Drugs & Pharmacology Source Type: news

Podcast: Selective serotonin reuptake inhibitors for stroke recovery
Stroke is a major cause of death and disability across the world, with many reviews from the Cochrane Stroke Group providing evidence on the effects of treatments and rehabilitation interventions. In November 2019, the Group published their update of their review of selective serotonin reuptake inhibitors and we asked lead author, Gillian Mead from the University of Edinburgh in Scotland, to tell us more.Stroke is a common cause of disability in the community. Although there have been major advances in the care of stroke patients over the last few years, many survivors are still left with physical disability, such as weakn...
Source: Cochrane News and Events - February 26, 2020 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Increased circulatory IL-6 during 8-week fluoxetine treatment is a risk factor for suicidal behaviors in youth - Amitai M, Taler M, Ben-Baruch R, Lebow M, Rotkopf R, Apter A, Fennig S, Weizman A, Chen A.
OBJECTIVE: Selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat anxiety and/or depression in pediatric populations. However, the response rates are low (approximately 50%). Moreover, SSRI use is frequently associated with adverse even... (Source: SafetyLit)
Source: SafetyLit - January 1, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Using antidepressants while pregnant can increase the risk of autism in newborns – study
(Natural News) Pregnant women can add antidepressants to their laundry list of things to avoid during pregnancy. The results of a recent study revealed that babies exposed to the pharmaceutical drug fluoxetine in the womb could develop autistic-like behavior later on. The study, published in the journal Molecular Brain, also identified a potential therapy for the problem,... (Source: NaturalNews.com)
Source: NaturalNews.com - December 3, 2019 Category: Consumer Health News Source Type: news

Amendments to Serious Shortage Protocols for fluoxetine 30mg capsules (England)
The Serious Shortage Protocols (SSP) for fluoxetine 30mg capsules has been varied... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - November 20, 2019 Category: Drugs & Pharmacology Source Type: news

Amendments to Serious Shortage Protocols for fluoxetine 40mg capsules (England)
The Serious Shortage Protocols (SSP) for fluoxetine 40mg capsules ... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - November 8, 2019 Category: Drugs & Pharmacology Source Type: news

Amendments to Serious Shortage Protocols for fluoxetine 30mg and 40mg capsules (England)
The Serious Shortage Protocols (SSP) for fluoxetine 30mg capsules and fluoxetine 40mg capsules are being varied to extend the end date, which was previously 31 October 2019. (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - October 30, 2019 Category: Drugs & Pharmacology Source Type: news

Withdrawal of Serious Shortage Protocol for fluoxetine 10mg capsule (England)
The Department of Health and Social Care (DHSC) has issued information about the withdrawal of Serious Shortage Protocol (SSP) for fluoxetine 10mg. (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - October 25, 2019 Category: Drugs & Pharmacology Source Type: news

Effect of Fluoxetine on Repetitive Behaviors in ASD Youth Unclear
WEDNESDAY, Oct. 23, 2019 -- Treatment with fluoxetine results in significantly lower scores for obsessive compulsive behaviors at 16 weeks among children and adolescents with autism spectrum disorder (ASD), according to a study published in the Oct.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 23, 2019 Category: Pharmaceuticals Source Type: news

What are the effects of fluoxetine treatment in overweight or obese adults?
Fluoxetine is a medicine used for the treatment of depression, which reduces appetite as a side effect. Therefore, it is suspected that fluoxetine could be used as a treatment for overweight or obese people. In this group of people administration of fluoxetine means an off-label treatment which means it is not licensed for treating obesity.The authors identified 19 randomised controlled trials (clinical studies where people are randomly put into one of two or more treatment groups) evaluating mainly women receiving different doses of fluoxetine. A total of 1280 overweight or obese participants received fluoxetine and 936 p...
Source: Cochrane News and Events - October 17, 2019 Category: Information Technology Authors: Katie Abbotts Source Type: news

Featured review: What are the effects of fluoxetine treatment in overweight or obese adults?
Fluoxetine is a medicine used for the treatment of depression, which reduces appetite as a side effect. Therefore, it is suspected that fluoxetine could be used as a treatment for overweight or obese people. In this group of people administration of fluoxetine means an off-label treatment which means it is not licensed for treating obesity.The authors identified 19 randomised controlled trials (clinical studies where people are randomly put into one of two or more treatment groups) evaluating mainly women receiving different doses of fluoxetine. A total of 1280 overweight or obese participants received fluoxetine and 936 p...
Source: Cochrane News and Events - October 17, 2019 Category: Information Technology Authors: Katie Abbotts Source Type: news

Serious shortage protocols (SSPs) for Fluoxetine (England)
The Department of Health and Social Care has agreed the October serious shortage protocols for the following items... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - October 3, 2019 Category: Drugs & Pharmacology Source Type: news

First Serious Shortage Protocols issued
The Government has authorised the first Serious Shortage Protocols (SSP), for the antidepressant fluoxetine, enabling pharmacists in England to supply an alternative strength or pharmaceutical form of (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - October 3, 2019 Category: Drugs & Pharmacology Source Type: news

Drug Supply issues: Provera100mg tablets and fluoxetine capsules
Information from the Department of Health and Social Care (DHSC) regarding the following supply issues... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 20, 2019 Category: Drugs & Pharmacology Source Type: news

Study shows how serotonin and a popular anti-depressant affect the gut ’s microbiota
In this study, we were interested in finding out why they might do so,” said Hsiao, UCLA assistant professor of integrative biology and physiology, and of microbiology, immunology and molecular genetics in the  UCLA College; and of digestive diseases in the David Geffen School of Medicine at UCLA.Hsiao and her research group reported in the journal Cell in 2015 that in mice, a specific mixture of bacteria, consisting mainly of  Turicibacter sanguinis and Clostridia, produces molecules that signal to gut cells to increase production of serotonin. When Hsiao’s team raised mice without the bact...
Source: UCLA Newsroom: Health Sciences - September 6, 2019 Category: Universities & Medical Training Source Type: news

Psychotherapy Alone First Line of Treatment for Depressed Youth
Adding fluoxetine to cognitive behavioral therapy did not further reduce depressive symptoms (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - August 12, 2019 Category: Psychiatry Tags: Family Medicine, Pediatrics, Pharmacy, Psychiatry, Journal, Source Type: news

The addition of fluoxetine to cognitive behavioural therapy for youth depression (YoDA-C): a randomised, double-blind, placebo-controlled, multicentre clinical trial - Davey CG, Chanen AM, Hetrick SE, Cotton SM, Ratheesh A, Amminger GP, Koutsogiannis J, Phelan M, Mullen E, Harrison BJ, Rice S, Parker AG, Dean OM, Weller A, Kerr M, Quinn AL, Catania L, Kazantzis N, McGorry PD, Berk M.
BACKGROUND: Medication is commonly used to treat youth depression, but whether medication should be added to cognitive behavioural therapy (CBT) as first-line treatment is unclear. We aimed to examine whether combined treatment with CBT and fluoxetine was ... (Source: SafetyLit)
Source: SafetyLit - August 4, 2019 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

How a popular antidepressant drug could rewire the brain
(American Chemical Society) Prozac ® , the trade name for the drug fluoxetine, was introduced to the US market for the treatment of depression in 1988. Thirty years later, scientists still don't know exactly how the medication exerts its mood-lifting effects. Now, researchers report that, in addition to the drug's known action on serotonin receptors, fluoxetine could rearrange nerve fibers in the hippocampus of mouse brains. They report their results in ACS Chemical Neuroscience. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 10, 2019 Category: International Medicine & Public Health Source Type: news

fluoxetine (Prozac, Sarafem, Prozac Weekly)
Title: fluoxetine (Prozac, Sarafem, Prozac Weekly)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 7/3/2019 12:00:00 AM (Source: MedicineNet Depression General)
Source: MedicineNet Depression General - July 3, 2019 Category: Psychiatry Source Type: news

Zoloft (sertraline) vs. Prozac (fluoxetine)
Title: Zoloft (sertraline) vs. Prozac (fluoxetine)Category: MedicationsCreated: 6/26/2019 12:00:00 AMLast Editorial Review: 6/26/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - June 26, 2019 Category: Drugs & Pharmacology Source Type: news

AMP-Activated Protein Kinase: Potential Target for TNBC AMP-Activated Protein Kinase: Potential Target for TNBC
Metformin, fluoxetine, and other AMPK agonists significantly inhibit TNBC. Will targeted therapy finally become an option for this aggressive disease?Breast Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 26, 2019 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Lupin launches generic antidepressant tablets in US
The company has launched its Fluoxetine tablets USP in the strength of 60mg after having received an approval from the United States Food and Drug Administration. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - April 10, 2019 Category: Pharmaceuticals Source Type: news

A commonly-used antidepressant doesn't improve recovery after stroke
The antidepressant fluoxetine works no better than placebo to reduce disability after a stroke, lowering hopes that had been raised by other smaller studies. After a six month trial including more than 3,000 adult stroke patients recruited at 103 UK hospitals, researchers concluded that fluoxetine should not be used to promote recovery from stroke-related disability, or routinely prescribed to prevent depression after stroke. Several smaller studies and animal trials had found promising results from the use of fluoxetine after stroke. However, this trial of fluoxetine 20mg daily for six months found no improvement in funct...
Source: Current Awareness Service for Health (CASH) - February 18, 2019 Category: Consumer Health News Source Type: news

Effects of Antidepressants Span Three Generations in Fish
Fluoxetine dampened stress responses in zebrafish embryos exposed to the drug--and their descendants. (Source: The Scientist)
Source: The Scientist - December 10, 2018 Category: Science Tags: News & Opinion Source Type: news

New Drug Option Fails for Rare Polio-Like Virus in Kids New Drug Option Fails for Rare Polio-Like Virus in Kids
Despite initial hope, fluoxetine failed to improve outcomes in children with acute flaccid myelitis and in some cases was linked to a worsening of the disorder, which can cause permanent paralysis in children.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 14, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

No Efficacy Signal for Fluoxetine in EV-D68 Acute Flaccid Myelitis
TUESDAY, Nov. 13, 2018 -- The antiviral agent fluoxetine is well tolerated but is not effective for patients with proven or presumptive enterovirus D68-associated acute flaccid myelitis (AFM), according to a study published online Nov. 9 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 13, 2018 Category: Pharmaceuticals Source Type: news