Open water swimming as a treatment for major depressive disorder - van Tulleken C, Tipton M, Massey H, Harper CM.
A 24-year-old woman with symptoms of major depressive disorder and anxiety had been treated for the condition since the age of 17. Symptoms were resistant to fluoxetine and then citalopram. Following the birth of her daughter, she wanted to be medication-f... (Source: SafetyLit)
Source: SafetyLit - August 24, 2018 Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news

Antidepressant restores youthful flexibility to aging inhibitory neurons in mice
(Picower Institute at MIT) Inhibitory neurons in the aging brain show reduced growth and plasticity, likely contributing to declines in brain function. In a new study in mice researchers at the Picower Institute at MIT show that treatment with fluoxetine restored substantial growth and plasticity. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2018 Category: International Medicine & Public Health Source Type: news

Medical News Today: What is fluoxetine?
Fluoxetine oral capsule is a prescription medication used to treat conditions such as depression, obsessive-compulsive disorder (OCD), eating disorders, and panic attacks. It comes as the brand-name drugs Prozac and Prozac Weekly, and as a generic drug. Learn about side effects, warnings, dosage, and more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 12, 2018 Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

My OCD story: evidence-based medicine to the rescue!
Karen Morley blogs about her experience of seeking help for her Obsessive-Compulsive Disorder (OCD) and how finding and using Cochrane evidence was a turning point. This blog post was originally published onEvidently Cochrane.Without knowing what it was, I had experienced episodes of Obsessive-Compulsive Disorder (OCD) since I was an adolescent, usually when I was particularly stressed. But it was when I was caring full time for my mother, who had multiple conditions including dementia, that I had an unusually distressing episode of contamination-related OCD. When I took to the internet I was amazed to discover that the ob...
Source: Cochrane News and Events - June 27, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

My OCD story: evidence-based medicine to the rescue!
Karen Morley blogs about her experience of seeking help for her Obsessive-Compulsive Disorder (OCD) and how finding and using Cochrane evidence was a turning point. This blog post was originally published onEvidently Cochrane.Without knowing what it was, I had experienced episodes of Obsessive-Compulsive Disorder (OCD) since I was an adolescent, usually when I was particularly stressed. But it was when I was caring full time for my mother, who had multiple conditions including dementia, that I had an unusually distressing episode of contamination-related OCD. When I took to the internet I was amazed to discover that the ob...
Source: Cochrane News and Events - June 27, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

The Drugs That Changed Our Minds by Lauren Slater – review
Twenty years after hailing antidepressants in her memoir Prozac Diary, a now jaded, sceptical Lauren Slater revisits the psychopharmacological industry – with uneven resultsInProzac Diary (1998), Lauren Slater wrote powerfully of the way fluoxetine had transformed her previously chaotic life. While the author recorded a handful of negative side-effects – a profound loss of libido, for instance – the reader was left with the sense that Prozac had pieced back together the shards of Slater’s existence. In some ways,The Drugs That Changed Our Minds is a sequel to that book. Slater is now in her mid-50s, recently divorc...
Source: Guardian Unlimited Science - April 1, 2018 Category: Science Authors: Alex Preston Tags: Autobiography and memoir Science and nature Books Medical research Depression Society Culture Source Type: news

Antidepressants do work – but children need someone to talk to
Young people in mental distress need – and deserve – faster access to support services, as well as pillsNearly a decade ago I found myself perched on the edge of a hard chair in a dark doctor ’s office. I was 13 and struggling a lot with self harm, body image, and the simple task of keeping myself alive. Shuffling my feet and wondering how I ended up here, I remember not fully understanding what was happening when I was handed a little green prescription for Fluoxetine – an antidepre ssant drug often better known as Prozac.Back then, my frame of reference for mental illness was pretty minimal. All I knew was that I...
Source: Guardian Unlimited Science - March 4, 2018 Category: Science Authors: Alice Gibbs Tags: Depression Mental health Psychiatry Society Drugs Science Source Type: news

Fluoxetine Capsules (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 23, 2018 Category: Drugs & Pharmacology Source Type: news

These Antidepressants Are Most Effective, Study Says
Millions of people take antidepressants for depression. But there’s long been debate over just how effective the medications actually are. On Wednesday, a large new study provides evidence that antidepressants are more effective than placebo at treating acute depression in adults. The study, published in the journal The Lancet, looked at the published data from 522 randomized controlled trials testing 21 different types of antidepressants. The study authors also reached out to pharmaceutical companies and study authors for additional unpublished study data. All told, the data collection included 116,477 men and women...
Source: TIME: Health - February 21, 2018 Category: Consumer Health News Authors: Alexandra Sifferlin Tags: Uncategorized healthytime Mental Health/Psychology Source Type: news

Exploring the History & Treatment of PTSD: An Interview with Dr. Paula P. Schnurr
As we celebrate Veterans Day (and Remembrance Day in Canada) and honoring military veterans, many of us think back to World War I but also many other wars throughout history. I recalled the 1980s, when Iran was engaged in an almost decade-long war with Iraq, and millions were killed or injured on both sides. In the West, the older generations may recall World War II and the Vietnam War, while the younger ones remember the more recent wars in Iraq and Afghanistan. We think of the millions who have fought, who have come back with injuries, and those who died serving their countries. But the numbers we rarely think about: How...
Source: Psych Central - November 11, 2017 Category: Psychiatry Authors: Arash Emamzadeh Tags: Interview Medications PTSD Trauma Treatment Combat Trauma Posttraumatic Stress Disorder PSTD Traumatic Experiences veterans Veterans day Source Type: news

Abrogated Freud-1/CC2D1A repression of 5-HT1A autoreceptors induces fluoxetine-resistant anxiety/depression-like behavior - Vahid-Ansari F, Daigle M, Manzini MC, Tanaka KF, Hen R, Geddes SD, B éïque JC, James J, Merali Z, Albert PR.
Freud-1/CC2D1A represses the gene transcription of serotonin-1A (5-HT1A) autoreceptors, which negatively regulate 5-HT tone. To test the role of Freud-1 in vivo, we generated mice with adulthood conditional knockout of Freud-1 in 5-HT neurons (cF1ko). In c... (Source: SafetyLit)
Source: SafetyLit - November 8, 2017 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Olanzapine and Fluoxetine (Symbyax) Capsules (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - September 25, 2017 Category: Drugs & Pharmacology Source Type: news

Antidepressant Plus CBT May Ease Hypochondria Antidepressant Plus CBT May Ease Hypochondria
Fluoxetine may help ease hypochondriasis, and adding cognitive-behavioral therapy (CBT) provides a small incremental benefit, new research shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 12, 2017 Category: Consumer Health News Tags: Psychiatry News Source Type: news

5 things parents should know about eating disorders
Dr. Sara Forman, director of Boston Children’s Hospital’s Outpatient Eating Disorders Program and Dr. Tracy Richmond, director of the PREP weight management program in Adolescent Medicine, share five things parents should know about eating disorders. Kids don’t have to be really thin to have an eating disorder. Not everyone with an eating disorder looks like he or she has an eating disorder. The condition is often hidden in secret habits or obsessions. For example, binge eating and bulimia — or binging and purging — are common eating disorders not necessarily associated with thinness. Eating diso...
Source: Thrive, Children's Hospital Boston - July 7, 2017 Category: Pediatrics Authors: Erin Horan Tags: Mental Health Teen Health anorexia anorexia nervosa bulimia Dr. Sara Forman Dr. Tracy Richmond eating disorder Source Type: news

Analysis examines safety of antidepressant use during pregnancy
Use of fluoxetine -- the most commonly prescribed antidepressant -- during pregnancy is linked with a slightly increased risk of malformations in infants, according to a recent analysis. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 17, 2017 Category: Science Source Type: news