These Antidepressants Are Most Effective, Study Says

Millions of people take antidepressants for depression. But there’s long been debate over just how effective the medications actually are. On Wednesday, a large new study provides evidence that antidepressants are more effective than placebo at treating acute depression in adults. The study, published in the journal The Lancet, looked at the published data from 522 randomized controlled trials testing 21 different types of antidepressants. The study authors also reached out to pharmaceutical companies and study authors for additional unpublished study data. All told, the data collection included 116,477 men and women, ages 18 and older, who had depression and who were treated for at least eight weeks. The researchers found that every type of antidepressant they studied was more effective at lessening symptoms of depression over time than placebo. They considered a drug “effective” if it reduced depression symptoms by 50% or more. The researchers expected to find that some antidepressants would prove to be better than placebo, but they were surprised that every drug was more effective, says lead study author Dr. Andrea Cipriani of the University of Oxford in the UK. “We were open to any result,” he says. “This is why we can say this is the final answer to the controversy.” MORE: A New Hope For Depression Though researchers found that every drug was more effective than placebo, some were more effective than others. The most effective w...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime Mental Health/Psychology Source Type: news

Related Links:

Condition:   Postpartum Depression Intervention:   Behavioral: Group Interpersonal Psychotherapy Sponsors:   McMaster University;   Hamilton Academic Health Sciences Organization Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Anxiety Depression Intervention:   Behavioral: Psychotherapy Sponsor:   NYU Langone Health Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Postpartum Depression Intervention:   Behavioral: Group Interpersonal Psychotherapy Sponsors:   McMaster University;   Hamilton Academic Health Sciences Organization Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Anxiety Depression Intervention:   Behavioral: Psychotherapy Sponsor:   NYU Langone Health Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
BackgroundDuring the COVID-19 pandemic, the Working Group “Prevention and Integrative Oncology” (PRIO) in the German Cancer Society has initiated flash interviews and surveys. One of these stated increasing rates of fears and mental stress of tumor patients. Now we aimed to analyze whether tumor patients did perceive changes in their attitudes and behaviors related to their relationships, awareness of nature and quietness, interest in spiritual issues, or feelings of worries and isolation. A further point of interest was how these perceived changes could be predicted, either by meaning in life, spirituality as ...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
In today’s show, Gabe talks with Robert Kolker, author of the New York Times bestselling — and Oprah’s book club pick — book Hidden Valley Road. This non-fiction biography is the true story of a mid-century American family besieged by schizophrenia. Of their 12 children, 6 struggled with the severe mental disorder.  Join us for the incredible story of the family who became science’s greatest hope in the quest to understand schizophrenia. SUBSCRIBE &REVIEW   Guest information for ‘Robert Kolker- Large Family Schizophrenia’ Podcast Episode Robert Kolker is the...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Family General Interview Schizophrenia The Psych Central Show Source Type: blogs
Treatment recommendations suggest that suicidal ideation will decrease following successful psychotherapy for depression. However, findings from the empirical research are equivocal in this regard. It is possi...
Source: BMC Psychiatry - Category: Psychiatry Authors: Tags: Research article Source Type: research
Suicide is a significant public health priority for older adults, who exhibit the highest suicide rates around the world.1 In this population, functional disability has been identified as a significant factor associated with greater risk and severity of suicide ideation.2 Older adults are most likely to experience functional disability (difficulties carrying out life activities), with about one-third of those age 65 and older, and more than two-thirds of those age 85 and older, experiencing disability.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Brief Report Source Type: research
Conclusion In this so far longest-running clinical trial, methylphenidate treatment was safe and well-tolerated. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Pharmacopsychiatry - Category: Psychiatry Authors: Tags: Original Paper Source Type: research
Authors: Hamilton J, Saxon D, Best E, Glover V, Walters SJ, Kerr IB Abstract A pilot study of cognitive analytic therapy (CAT) plus treatment as usual (TAU), versus TAU in stressed pregnant women with anxiety and depression was undertaken as an essential preliminary to any definitive, randomised controlled trial (RCT). The trial was pragmatic, multicentre, parallel, randomised, controlled, and unblinded. Participants were pregnant woman screened using the Hospital Anxiety and Depression Scale (HADS). Treatment was standard 16 session CAT. Main outcome measures: Spielberger State/Trait Anxiety Inventory (STAI) (prim...
Source: Clinical Psychology and Psychotherapy - Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research
More News: Amitriptyline | Depression | Effexor | Fluoxetine | Health | Lexapro | Men | Mirtazapine | Oxford University | Paroxetine | Paxil | Prozac | Psychology | Psychotherapy | Study | Trazodone | Women