Active microscopic colitis precipitated by fluoxetine
We present the case of a patient diagnosed with active microscopic colitis in relation to taking fluoxetine at high doses.PMID:38634864 | DOI:10.17235/reed.2024.10336/2024 (Source: Revista Espanola de Enfermedades Digestivas)
Source: Revista Espanola de Enfermedades Digestivas - April 18, 2024 Category: Gastroenterology Authors: Flor M Fern ández-Gordón Sánchez Celia G ómez Labrador Luis Wong Becerra Bairon Alfoso Paz Fern ández Ana Patricia Mart ínez Aguilar Carlos Casta ño-Milla Source Type: research
Psychotropic Management in Cotard Syndrome: Case Reports Supporting Dual Medication Management
Case Rep Psychiatry. 2024 Apr 9;2024:7630713. doi: 10.1155/2024/7630713. eCollection 2024.ABSTRACTCotard syndrome is a rare presentation where patients present with nihilistic thoughts of dying or already being dead. These delusions manifest from either a medical or psychiatric etiology and can be difficult to treat. Recently Couto and Gonçalves purposed that treatment should include an atypical antipsychotic alone or in combination with either a mood stabilizer or antidepressant. Here the authors advocate for a more specific but well-known psychotropic regimen, namely the combination of olanzapine and fluoxetine. We cond...
Source: Case Reports in Psychiatry - April 18, 2024 Category: Psychiatry Authors: Adam J Fusick Chemar Davis Steven Gunther Cory Klippel Gregory Sullivan Source Type: research
Effectiveness of Antidepressants in Combination with Psychotherapy
This study reports the remission rates for the 14 most commonly prescribed single antidepressants (amitriptyline, bupropion, citalopram, desvenlafaxine, doxepin, duloxetine, escitalopram, fluoxetine, mirtazapine, nortriptyline, paroxetine, sertraline, trazodone, and venlafaxine) and a category named "Other" (other antidepressants/combination of antidepressants). The study used robust LASSO regressions to identify factors that affected remission rate and clinicians' selection of antidepressants. The selection bias in observational data was removed through stratification. We organized the data into 16,770 subgroups, of at le...
Source: Journal of Mental Health Policy and Economics - April 18, 2024 Category: Psychiatry Authors: Farrokh Alemi Tulay G Soylu Mary Cannon Conor McCandless Source Type: research
Psychotropic Management in Cotard Syndrome: Case Reports Supporting Dual Medication Management
Case Rep Psychiatry. 2024 Apr 9;2024:7630713. doi: 10.1155/2024/7630713. eCollection 2024.ABSTRACTCotard syndrome is a rare presentation where patients present with nihilistic thoughts of dying or already being dead. These delusions manifest from either a medical or psychiatric etiology and can be difficult to treat. Recently Couto and Gonçalves purposed that treatment should include an atypical antipsychotic alone or in combination with either a mood stabilizer or antidepressant. Here the authors advocate for a more specific but well-known psychotropic regimen, namely the combination of olanzapine and fluoxetine. We cond...
Source: Case Reports in Psychiatry - April 18, 2024 Category: Psychiatry Authors: Adam J Fusick Chemar Davis Steven Gunther Cory Klippel Gregory Sullivan Source Type: research
Active microscopic colitis precipitated by fluoxetine
We present the case of a patient diagnosed with active microscopic colitis in relation to taking fluoxetine at high doses.PMID:38634864 | DOI:10.17235/reed.2024.10336/2024 (Source: Revista Espanola de Enfermedades Digestivas)
Source: Revista Espanola de Enfermedades Digestivas - April 18, 2024 Category: Gastroenterology Authors: Flor M Fern ández-Gordón Sánchez Celia G ómez Labrador Luis Wong Becerra Bairon Alfoso Paz Fern ández Ana Patricia Mart ínez Aguilar Carlos Casta ño-Milla Source Type: research
Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study
Conclusions
Infants exposed to SSRIs have increased risks of delayed adaptation in a type and dose-dependent relationship, pointing toward a causal relationship. (Source: Archives of Disease in Childhood - Fetal and Neonatal Edition)
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - April 18, 2024 Category: Perinatology & Neonatology Authors: Cornet, M.-C., Wu, Y. W., Forquer, H., Avalos, L. A., Sriram, A., Scheffler, A. W., Newman, T. B., Kuzniewicz, M. W. Tags: Open access Original research Source Type: research
Impact of chronic fluoxetine exposure on zebrafish: from fatty acid profile to behavior
Chemosphere. 2024 Apr 12:142026. doi: 10.1016/j.chemosphere.2024.142026. Online ahead of print.ABSTRACTThe consumption of antidepressants, such as fluoxetine, has increased over the years and, as a result, they are increasingly found in aquatic systems. Given the increasing use of zebrafish as an animal model in toxicological studies, this work proposed to evaluate the effects of chronic exposure, for 21 days, to fluoxetine at environmentally relevant concentrations (1, 10, 100, and 1000 ng/L). The behavioral tests performed did not reveal significant effects of fluoxetine. However, oxidative stress and changes in energy m...
Source: Chemosphere - April 14, 2024 Category: Chemistry Authors: Bruno Pinto Daniela Correia Tiago Conde Melissa Faria Miguel Oliveira Maria do Ros ário Domingues In ês Domingues Source Type: research
Impact of chronic fluoxetine exposure on zebrafish: from fatty acid profile to behavior
Chemosphere. 2024 Apr 12:142026. doi: 10.1016/j.chemosphere.2024.142026. Online ahead of print.ABSTRACTThe consumption of antidepressants, such as fluoxetine, has increased over the years and, as a result, they are increasingly found in aquatic systems. Given the increasing use of zebrafish as an animal model in toxicological studies, this work proposed to evaluate the effects of chronic exposure, for 21 days, to fluoxetine at environmentally relevant concentrations (1, 10, 100, and 1000 ng/L). The behavioral tests performed did not reveal significant effects of fluoxetine. However, oxidative stress and changes in energy m...
Source: Chemosphere - April 14, 2024 Category: Chemistry Authors: Bruno Pinto Daniela Correia Tiago Conde Melissa Faria Miguel Oliveira Maria do Ros ário Domingues In ês Domingues Source Type: research
The oxytocin receptor is essential for the protective effect of pair housing on post-stroke depression in mice
In conclusion, pair housing protects against the development of PSD depending on OXT and OXTR in the brain, with no significant divergence based on sex. These findings provide valuable insights into the potential of social interaction and oxytocin as therapeutic targets for PSD. Further research into the underlying mechanisms of these effects may contribute to the development of novel treatments for PSD.PMID:38614224 | DOI:10.1016/j.exger.2024.112432 (Source: Experimental Gerontology)
Source: Experimental Gerontology - April 13, 2024 Category: Geriatrics Authors: Su-Ting Jiang Shu-Ying Lian Yao-Huan Sun Mei-Bo Pan Bin Wang Hui Wang Jun Hua Yi-Chen Wang Qiu-Ling Wang Yin-Feng Dong Source Type: research
The oxytocin receptor is essential for the protective effect of pair housing on post-stroke depression in mice
In conclusion, pair housing protects against the development of PSD depending on OXT and OXTR in the brain, with no significant divergence based on sex. These findings provide valuable insights into the potential of social interaction and oxytocin as therapeutic targets for PSD. Further research into the underlying mechanisms of these effects may contribute to the development of novel treatments for PSD.PMID:38614224 | DOI:10.1016/j.exger.2024.112432 (Source: Experimental Gerontology)
Source: Experimental Gerontology - April 13, 2024 Category: Geriatrics Authors: Su-Ting Jiang Shu-Ying Lian Yao-Huan Sun Mei-Bo Pan Bin Wang Hui Wang Jun Hua Yi-Chen Wang Qiu-Ling Wang Yin-Feng Dong Source Type: research
The oxytocin receptor is essential for the protective effect of pair housing on post-stroke depression in mice
In conclusion, pair housing protects against the development of PSD depending on OXT and OXTR in the brain, with no significant divergence based on sex. These findings provide valuable insights into the potential of social interaction and oxytocin as therapeutic targets for PSD. Further research into the underlying mechanisms of these effects may contribute to the development of novel treatments for PSD.PMID:38614224 | DOI:10.1016/j.exger.2024.112432 (Source: Experimental Gerontology)
Source: Experimental Gerontology - April 13, 2024 Category: Geriatrics Authors: Su-Ting Jiang Shu-Ying Lian Yao-Huan Sun Mei-Bo Pan Bin Wang Hui Wang Jun Hua Yi-Chen Wang Qiu-Ling Wang Yin-Feng Dong Source Type: research
Cannabidiol Compared to Pharmacological Treatment as Usual for Crack Use Disorder: A Feasibility, Preliminary Efficacy, Parallel, Double-Blind, Randomized Clinical Trial
This study is registered with Universal Trial Number (UTN) code: U1111-1234-0806. Available athttps://ensaiosclinicos.gov.br/rg/RBR-4stgs8 (Effect of cannabidiol in the treatment of crack dependents) (Source: International Journal of Mental Health and Addiction)
Source: International Journal of Mental Health and Addiction - April 8, 2024 Category: Addiction Source Type: research
Parental exposure to antidepressants has lasting effects on offspring? A case study with zebrafish
Chemosphere. 2024 Apr 3:141851. doi: 10.1016/j.chemosphere.2024.141851. Online ahead of print.ABSTRACTFish have common neurotransmitter pathways with humans, exhibiting a significant degree of conservation and homology. Thus, exposure to fluoxetine makes fish potentially susceptible to biochemical and physiological changes, similarly to what is observed in humans. Over the years, several studies demonstrated the potential effects of fluoxetine on different fish species and at different levels of biological organization. However, the effects of parental exposure to unexposed offspring remain largely unknown. The consequence...
Source: Chemosphere - April 5, 2024 Category: Chemistry Authors: Daniela Correia Marina Bellot J úlia Goyenechea Eva Prats Hugo Moro Cristian G ómez-Canela Juliette Bedrossiantz Niki Tagkalidou Carla S S Ferreira Demetrio Rald úa In ês Domingues Melissa Faria Miguel Oliveira Source Type: research
Parental exposure to antidepressants has lasting effects on offspring? A case study with zebrafish
Chemosphere. 2024 Apr 3:141851. doi: 10.1016/j.chemosphere.2024.141851. Online ahead of print.ABSTRACTFish have common neurotransmitter pathways with humans, exhibiting a significant degree of conservation and homology. Thus, exposure to fluoxetine makes fish potentially susceptible to biochemical and physiological changes, similarly to what is observed in humans. Over the years, several studies demonstrated the potential effects of fluoxetine on different fish species and at different levels of biological organization. However, the effects of parental exposure to unexposed offspring remain largely unknown. The consequence...
Source: Chemosphere - April 5, 2024 Category: Chemistry Authors: Daniela Correia Marina Bellot J úlia Goyenechea Eva Prats Hugo Moro Cristian G ómez-Canela Juliette Bedrossiantz Niki Tagkalidou Carla S S Ferreira Demetrio Rald úa In ês Domingues Melissa Faria Miguel Oliveira Source Type: research
