Paeoniflorin suppresses the apoptosis and inflammation of human coronary artery endothelial cells induced by oxidized low-density lipoprotein by regulating the Wnt/ β-catenin pathway

CONCLUSIONS: This study first revealed that PF inhibited ox-LDL-induced HCAECs apoptosis and inflammation via the Wnt/β-catenin pathway and alleviated CAD, suggesting the potential of PF as a drug for CAD treatment.PMID:37674320 | PMC:PMC10486282 | DOI:10.1080/13880209.2023.2220360
Source: Pharmaceutical Biology - Category: Drugs & Pharmacology Authors: Source Type: research