Identification of Rab7 as an autophagy marker: potential therapeutic approaches and the effect of Qi Teng Xiao Zhuo granule in chronic glomerulonephritis
CONCLUSION: TCM CGN-regulating herbs (QTXZG) can exert therapeutic effects by affecting the Rab7/Pink1/Parkin pathway to promote mitochondrial autophagy. New breakthroughs in targeted Rab7 may eventually enable such applications.PMID:37477949 | PMC:PMC10364565 | DOI:10.1080/13880209.2023.2233998 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - July 21, 2023 Category: Drugs & Pharmacology Authors: Xiujuan Qin Huiyu Chen Xiaoli Zhu Xianjin Xu Jiarong Gao Source Type: research
Identification of Rab7 as an autophagy marker: potential therapeutic approaches and the effect of Qi Teng Xiao Zhuo granule in chronic glomerulonephritis
CONCLUSION: TCM CGN-regulating herbs (QTXZG) can exert therapeutic effects by affecting the Rab7/Pink1/Parkin pathway to promote mitochondrial autophagy. New breakthroughs in targeted Rab7 may eventually enable such applications.PMID:37477949 | DOI:10.1080/13880209.2023.2233998 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - July 21, 2023 Category: Drugs & Pharmacology Authors: Xiujuan Qin Huiyu Chen Xiaoli Zhu Xianjin Xu Jiarong Gao Source Type: research
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation
CONCLUSION: The present study reveals that DMY suppresses EGFR and its downstream pathways by reducing cholesterol to disrupt lipid rafts, thereby inhibiting HCC, which provides a promising candidate drug with low toxicity for the treatment of HCC.PMID:37462387 | PMC:PMC10355694 | DOI:10.1080/13880209.2023.2234000 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - July 18, 2023 Category: Drugs & Pharmacology Authors: Shuo Zhang Ya-Ning Shi Jia Gu Peng He Qi-Di Ai Xu-Dong Zhou Wei Wang Li Qin Source Type: research
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation
CONCLUSION: The present study reveals that DMY suppresses EGFR and its downstream pathways by reducing cholesterol to disrupt lipid rafts, thereby inhibiting HCC, which provides a promising candidate drug with low toxicity for the treatment of HCC.PMID:37462387 | DOI:10.1080/13880209.2023.2234000 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - July 18, 2023 Category: Drugs & Pharmacology Authors: Shuo Zhang Ya-Ning Shi Jia Gu Peng He Qi-Di Ai Xu-Dong Zhou Wei Wang Li Qin Source Type: research
Prevalence, motivation, and associated factors of medicinal herbs consumption in pregnant women from Eastern Mediterranean Regional Office: a systematic review
CONCLUSIONS: The wide variety of herbal products used in this study reflects the traditions and geographic diversity of the region. Despite the importance of literature-based data about the use of herbal medicine, it is necessary to obtain knowledge, attitude, and motivation for herbal consumption among pregnant women.PMID:37452524 | PMC:PMC10351469 | DOI:10.1080/13880209.2023.2229388 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - July 15, 2023 Category: Drugs & Pharmacology Authors: Afaf Bouqoufi Laila Lahlou Fatima Ait El Hadj Mohammed Abdessadek Majdouline Obtel Youssef Khabbal Source Type: research
Prevalence, motivation, and associated factors of medicinal herbs consumption in pregnant women from Eastern Mediterranean Regional Office: a systematic review
CONCLUSIONS: The wide variety of herbal products used in this study reflects the traditions and geographic diversity of the region. Despite the importance of literature-based data about the use of herbal medicine, it is necessary to obtain knowledge, attitude, and motivation for herbal consumption among pregnant women.PMID:37452524 | DOI:10.1080/13880209.2023.2229388 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - July 15, 2023 Category: Drugs & Pharmacology Authors: Afaf Bouqoufi Laila Lahlou Fatima Ait El Hadj Mohammed Abdessadek Majdouline Obtel Youssef Khabbal Source Type: research
Correction
Pharm Biol. 2023 Dec;61(1):1107. doi: 10.1080/13880209.2023.2235925.NO ABSTRACTPMID:37449769 | DOI:10.1080/13880209.2023.2235925 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - July 14, 2023 Category: Drugs & Pharmacology Source Type: research
Effect-enhancing and toxicity-reducing effects of Chaihu Jia Longgu Muli decoction in the treatment of multimorbidity with depression: a systematic review and meta-analysis
CONCLUSIONS: CLMD combined with antidepressants enhances the effect of antidepressants and reduces their adverse reactions, performing a synergistic effect; it may be considered as an effective option in the treatment of MMD.PMID:37439185 | DOI:10.1080/13880209.2023.2228356 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - July 13, 2023 Category: Drugs & Pharmacology Authors: Xurui Jia Jie Chen Ruiou Huang Dawei Wang Xing Wang Source Type: research
Transcriptomic analysis reveals the regulatory mechanism underlying the indirubin-mediated amelioration of dextran sulfate sodium-induced colitis in mice
CONCLUSION: Apart from the well-documented NF-κB signalling pathway, IL-17A, and NLRP3-IL-1β, the suppression of haemoglobin-induced lipid peroxidation could be a previously unknown mechanism of IDR. Our study can help improve its application for UC treatment.PMID:37439220 | DOI:10.1080/13880209.2023.2233565 (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - July 13, 2023 Category: Drugs & Pharmacology Authors: Zhe Liu Jin-Ru Zhang Yong-Xiang Huang Xue-Ying Li Hai-Peng Zhu Rui-Yi Yang Song Chen Source Type: research
